Papillary Carcinoma (Definition) A malignant epithelial tumour showing evidence of follicular cell differentiation and characterized by distinctive nuclear features
Carcinoma Papilar de Tiroides • Cualquier edad • Poco agresivo • El más frecuente (especuialmente en zonas no bociógenas • Diseminación por vía linfática
Carcinoma Papilar de Tiroides (Pronóstico) • • • •
Edad Tamaño Invasión extratiroidea Metástasis a distancia
Papillary Carcinoma (size variation) • The term Microcarcinoma should be used for a papillary carcinoma , which is incidentally found, and measures 1 cm or less.
Follicular Carcinoma (Definition) A malignant epithelial tumour showing evidence of follicular cell differentiation, lacking the diagnostic nuclear features of papillary carcinoma
Poorly differentiated Carcinoma (Definition) Follicular-cell neoplasms that show limited evidence of structural follicular cell differentiation and occupy both morphologically and behaviourally an intermediate position between the well differentiated follicular and papillary carcinomas and the undifferentiated carcinomas
Poorly differentiated Carcinoma (Histopathology) • Three patterns (insular, trabecular, solid) • Infiltrative pattern of growth, necrosis and obvious vascular invasion • Prognostic significance of minor component is unknown
Undifferentiated (Anaplastic) Carcinoma (Definition) Highly malignant tumours that by standard light microscopy appear wholly or partially composed of undifferentiated cells that exhibit immunohistochemical or ultrastructural features indicating epithelial differentiation
Medullary Thyroid Carcinoma (Definition) A malignant tumour of the thyroid gland showing C-cell differentiation and lacking follicular differentiation.
