TOXICOLOGIA AINES

UNIVERSIDAD PRIVA PRIVADA DA NORBERT WIENER ESCUELA ACADEMICA PROFESIONAL DE FA FARMACIA RMACIA Y BIOQUIMICA

CURSO: TOXICOLOGIA Y QUIMICA LEGAL PRACTICA Nº9 TEMA: DETERMINACION DE AINES

INTEGRANTES:       

ALVARADO LOPEZ , LESLY CASTRO BOLAÑOS, CINTHIA GALARZA QUINTANA, ALEX GARCIA CHAVEZ, YELSON ORTEGA PONCE, DANY PARES QUISPE, LIZETH SANTA CRUZ OLIVOS, EDGAR

PROFESOR: Dr. JOSE ANTONIO LLAHUILLA QUEA.

SECCIÓN: FB9M

FECHA DE ENTREGA: !"#!$#$

LIMA – PERÚ

201 Importancia de la práctica práctica

TOXI TO XICO COL LOG A Y QU QU MI MICA CA •

Esta práctica es muy importante, porque nos permite identificar mediante reacciones de coloración y la cuantificación de ácido acetilsalicílico por el método de Trinder, de los diferentes tóxicos. Las reacciones de coloración nos ayuda a identificar los salicilatos, pirazolonas y paracetamol además de hidrocaruros.

•

Extraer, Extraer, purificar, purificar, identificar y cuantificar los salicilatos e interpretar toxicoló!icamente su concentración en líquidos ioló!icos. "alorar "alorar su importancia como a!ente tóxico causal cau sal de intoxicaciones, y proponer medidas pre#ención y tratamiento.

$arco teórico% teórico%

Salicilatos L%& &'()*)('+%& &% -r/'*%& *% 0r%0)12'21& '+))-('/'+%r)'&, ''(34&)*'& 5 '+)0)r4+)*'& *%/% r1&6(+'2% 21 (' )7)8)*) 21 (' 1:)/ 1:)/'' *)*(%% *)*(%%;)3 ;)31' 1'&' &' 61 0%&)8) 0%&)8)()+ ()+'' (' &?+1& &?+1&)& )& 21 0r%&+' 0r%&+'3(' 3('2) 2)' '&& 5, /12)'2 /12)'2%r1 %r1&& 21 (' )-('/ )-('/'*) '*). . C%&+)+651 6 3r60% 21 *%/061&+%& 21r)@'2%& 21( *)2% &'()*?()*% '&0)r)'  % *)2% '*1+)(&'()*?()*% <1( -r/'*% /& )/0%r+'+1 21( 3r60%=, 01r% 1 61&+r% 0'?& 1;)&+1 +'/8)4 %+r'& &6&+'*)'& *%/1r*)'():'2'& 0'r' 6&% %r'( % 0'r1+1r'( <'*1+)(&'()*)('+% 21 ()&)', &'()*)('+% &2)*%, &'(&'('+% % *)2% &'()*)(&'()*?()*%, 2) 2)-(6)&'(, 1+*=, '&? *%/% 6' '/0()' @'r)12'2 21 0r10'r'*)%1& +0)*'& ' 8'&1 21 *)2% &'()*?()*% % >61 06121 *%+11r /1+)( &'()*)('+% <'*1)+1 21 36'(+1r)'=, *% ('& >61 &1 7' 21&*r)+% '(36'& )+%;)*'*)%1& 3r'@1&. L' )+%;)*'*) 1&, 7%5 2?', /6*7% /1%& -r1*61+1 >61 *% 0'r'*1+'/%(, r1-(1% 21 ('& '*+6'(1& +121*)'& 1 (' 0r1&*r)0*) 21 '&0)r)' 5 21r)@'2%& <&%8r1 +%2% +r'& 7'81r(%& '&%*)'2% ' &?2r%/1 21 R151=. L' 21&*r)0*) >61 &1 0r1&1+' ' *%+)6'*) 7'*1 r1-1r1*)' '( *)2% '*1+)(&'()*?()*%, 01r% (%& '&01*+%& -'r/'*%*)4+)*%&, *( *(?)*%& 5 +1r'046+)*%& &% +'/8)4 '0()*'8(1& 314r)*'/1+1 '( r1&+% 21 (%& *%/0%1+1& 21 1&+1 3r60%. Historia:

Sauce (Salix alba)

E $ E2'r2 S+%1 0r1&1+ 6 )-%r/1 1 (' R1'( S%*)12'2 21 M12)*)' I3(1&' 2%21 21+'(('8' ('& 0r%0)12'21& +1r'046+)*'& 21 (' *%r+1:' 21( &'6*1 8('*% 61 -%r/'8' *r)&+'(1& 21 &'8%r /65 '/'r3% ' /'r3% >61 &1 (('/ &'()*)'. Edward Stone (1802–1865)

PRACTICA N°10: DETERMINACION DE AINES

1

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2

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3

TOXI TO XICO COL LOG A Y QU QU MI MICA CA

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5

TOXI TO XICO COL LOG A Y QU QU MI MICA CA  

A**) &%8r1 1( *1+r% r1&0)r'+%r)%. D1&'*%0('/)1+% 1 (' -%&-%r)('*) %;)2'+)@'.

13 E,"% E,"%4 4+' +'&% &%(! (! .%*/ .%*/&" &"'' SNC: SNC: A )@1( *1+r% r1&0)r'+%r)% → ↑ FR → 7)01r@1+)('*) *1+r'( 5 '(*'(%&)& r1&0)r'+%r)'. o P'r' *%/01&'r 0H → ↑ 1;*r1*) r1'( 8)*'r8%'+% >61 &1 '*%/0'' 04r2)2' 21 '36', &%2)% 5 0%+'&)% → o 21&7)2r'+'*), 7)0%0%+'&1/)' 7)0%0%+'&1/)' 5 04r2)2' *'0'*)2'2 21 +'/0 21( 0('&/' → '*)2%&)& /1+'8()*'. L' 7)01r@ 7)01r@1+ 1+)(' )('*) *) → 7)0%* 7)0%*'0 '0)' )' → @'&%2)(' @'&%2)('+'*) +'*) 'r+1r)'( 'r+1r)'( 01r)-4r)* 01r)-4r)*'' >61 6+% 6+% 210(1*) 210(1*) @%(6/1 o 0('&/+)*% <21&7)2r'+'*)= <21&7)2r'+'*)= → 7)0%+1&) 1 )&>61/)' +)&6('r < ↑ 0r%26**) *)2% (*+)*% 5 0)r@)*%=. 23 ↑ Pr%26**) *'(%r < ↑ T= 5 ↑ 6+)():'*) 3(6*%&' 3(6*%&' <7)0%3(6*1/)'=, ↓ -(6% 0('&/+)*% r1'( <'*6/6('*) *)2%& )%r3)*%&=, )+1r-1r1*)'& *)*(% 21 r18& *1(6('r, ↓ /1+'8%()&/% ()0?2)*% 5 HC → '*6/6('*) *)2%& %r3)*%& 1&0'*)% 1;+r'*1(6('r → '*)2%&)& /1+'8()*'. 53 A+)'3r13'+1 0('>61+'r)%, ↑ -r'3)()2'2 *'0)('r 5 ↓ -'*+%r VII < ↓ TP=.

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