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PATHWAY HIPERBILIRUBINEMIA
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PATHWAY HIPERBILIRUBINEMIA
PATHWAY mindsetDeskripsi lengkap...
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Dian Sambhara
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PATHWAY HIPERBILIRUBINEMIA (SURIADI & RITA Y, 2001) Eritrosit
Hemoglobin
Hem
Besi/Fe
Globin
Bilirubin indirek
terjadi pd limpha
Makrofag Bilirubin berikatan Darah dengan albumin
terjadi dlm plasma
Melalui hati Bilirubin berikatan dg glukoronat/gula residu bilirubin bilirubin direk diekskresi ke kandung empedu kandung empedu ke duodenum Diekskresi melalui urine & feces Hepar yang belum matang, Eritroblastosis foetalis, sepsis, Penyakit inklusi sitomegalik, Rubela, toksoplasmosis kongenital Hati
terjadi di hati
melalui duktus billiaris
2
Bilirubin direk
Bilirubin bebas Sistemik Otak
Menetap
Letargi, kejang, opistotonus Resti kernikterus
Tidak mau menghisap
Resti kurang cairan
Resti injuri Fototerapi
Resti kerusakan integritas kulit
Gangguan rasa nyaman & aman
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