Daftar Obat-obatan Untuk Ibu Hamil Dan Menyusui

Lactation Risk Categories

Pregnancy Risk Categories

•

L1 (Paling Aman)

•

A (studi terkontrol menunjukkan tanpa resiko )

•

L2 (Aman)

•

B (tidak ada bukti risiko pada manusia)

•

L3 (Cukup Aman)

•

C (risiko tidak dapat dikesampingkan)

•

L4 (Kemungkinan Barbahaya)

•

D (bukti positif resiko)

•

L5 (Kontra Indikasi)

•

X (dikontraindikasikan untuk Ibu Hamil)

Generi name

!rade "ame

AAP approved?*

Pregnany %atation #isk #isk Category$$ Category $$ Category Category$$ $$

Analgesis (Pain&killers) 'more 'more Aetaminophen

!ylenol

Colhiine

Colhiine

 "efopam

Aupan

 

Approved/dise!i

B

L1

Approved

D

L4

Approved

&

"# 

Approved

&

L2

   

more Non-steroidal anti-inflammatory analgesics (NSAIDs) 'more Aapropaone (a (apaone)

#heumo*

 

+ipyrone ( banned in the ,- . & ,K )

 

Approved

&

"# 

/lufenami aid

&

 

Approved

&

"# 

Ibuprofen

Ad0il1 "uprin1 2otrin1 Pediaprofin

Approved

B (3st1 4nd trim5) D (6rd trim5)

L1

Approved

B (3st1 4nd trim5) D (6rd trim5)

L3

L2

Indomethain

Indoin

 

Ketorola

!oradol1 Aular    

Approved

B (3st1 4nd trim5) D (6rd trim5)

2efenami aid

Ponstan1 Ponstel

Approved

&

"# 

 "apro*en

Anapro*1  "aprosyn1  "apro*en1 Ale0e

Approved

B

L3 L4 (for hroni use)

Phenylbutaone

Butaolidine

Approved

&

"# 

Piro*iam

/eldene

Approved

B

L2

 

   

-uprofen

Profenal

 

Approved

&

"# 

!olmetin

!oletin

 

Approved

C

L3

Approved

B (3st1 4nd trim5) D (6rd trim5)

L3

Approved

C

L3

Approved

B

L2

Approved

B

L2 L3 (if used early  postpartum)

Narcotic analgesics 'more

Butorphanol

-tadol

Codeine

!ylenol 761 78

/entanyl

-ublimae

 

   

2eperidine

+emerol

2ethadone

+olophine

 

Approved

B

L3

2orphine

2orphine

 

Approved

B

L3

Propo*yphene

+ar0oet "1 Propaet1 +ar0on

Approved

C

L2

 

'ontents

 Anesthesia, Anesthetics [more]

Halothane

/luothane

 

Approved

C

L2

%idoaine

9yloaine

 

Approved

C

L2

2ethohe*ital

Bre0ital

Approved

B

L3

!hiopental

Pentothal

Approved

C

L3

   

Antaids1 GI meds

'ontents

Cimetidine (Antaid)

!agamet

 

Approved

B

L2

Cisapride (GI trat stimulant)

Propulsid

 

Approved

C

L2

 

Approved

&

L1

+omperidone (used for nausea . 0omiting1 stimulates 2otilum latation) 'more Antibiotis

'ontents

Amo*iillin

%arotid1 Amo*il

 

Approved

B

L1

Atreonam

Aatam

 

Approved

B

L2

Cefadro*il

,ltraef1 +urief 

Approved

B

L1

Cefaolin

Anef1 Kefol

Approved

B

L1

Cefota*ime

Claforan

 

Approved

B

L2

Cefo*itin

2efo*in

 

Approved

B

L1

Cefproil

Cefil

Approved

C

L1

Ceftaidime

Ceftaidime1

Approved

B

L1

 

 

 

/orta1 !a*idime Ceftria*one

#oephin

Ciproflo*ain 'more

Cipro

Clindamyin

Cleoin

:rythromyin

:&2yin1 :ry& tab1 :#;C1 Ilosone

/lero*ain

&

Gentamiin

Garamyin

Kanamyin

Kebeil1 Kantre*

2o*alatam

2o*am

 "itrofurantoin

2arobid


/lo*in

Peniillin

&

-treptomyin

-treptomyin

-ulbatam

&

-ulfiso*aole

 

Approved

B

L2

Approved

C

L3

Approved

B

L3

Approved

B

L1 L3 early  postnatal

Approved

&

"# 

Approved

C

L2

 

Approved

D

L2

 

Approved

&

"# 

Approved

B

L2

Approved

C

L2

Approved

B

L1

Approved

D

L3

Approved

&

"# 

Gantrisin1 Ao&   Gantrisin

Approved

C

L2

!etrayline

Ahromyin1 -umyin1 !erramyin

Approved

D

L2

!iarillin

!iarillin1 !iar1 !imentin

Approved

B

L1

!rimethoprim=sulfametho*aole

Proloprim1 !rimpe*

Approved

C

L3

   

   

       

 

 

 

Antioagulants

'ontents

Bishydro*youmarin (diumarol)

&

>arfarin

Coumadin1 Pan?arfin

   

Approved

&

"# 

Approved

D

L2

Antion0ulsants

'ontents

Carbamaepine

!egretol1 :pitol  

Approved

C

L2

:thosu*imide

@arontin

Approved

C

L4

2agnesium sulfate

:psom salt

Approved

B

L1

Phenytoin

+ilantin

Approved

D

L2

alproi aid

+epakene1 +epakote

Approved

D

L2

Antifungals

       

'ontents

/luonaole 'more

+ifluan

Ketoonaole

 "ioral -hampoo1  "ioral

 

Approved

C

L2

Approved

C

L2

Antihistamines 'more

'ontents

+e*brompheniramine maleate ?ith d&isoephedrine

&

/e*ofenadine

Allegra

%oratadine

Approved

&

"# 

 

Approved

C

L2

Claritin

 

Approved

B

L1

!erfenadine

-eldane

 

Approved

&

"# 

!riprolidine

Atidil1 Atifed

Approved

C

L1

 

 

Anti0irals

'ontents

Aylo0ir 'more

@o0ira*

Interferon&alpha 'more

Alferon "1 Interferon Alpha

 

Approved

C

L2

Approved

C

L2

Arthritis meds (see also pain meds) Gold salts

'ontents

#idaura1 2yohrysine1 -olganal

Approved

C

Asthma meds (see also steroids)

L5

'ontents

+yphylline

+ilor1 %ufyllin1   +yphylline

Approved

C

L3

!erbutaline

Brianyl1 Brethine

 

Approved

B

L2

!heophylline

Aminophylline1 uibron1 !heo& +ur 

Approved

C

L3

Contraepti0es1 Hormones 'more

'ontents

:stradiol

:stratab1 Permarin1 2enest

Clogestone

&

Contraepti0e pill ?ith estrogen=progesterone

Pre0en1 -easonale1  "orinyl1  "orlestin1
 

Approved

X

L3 (may interfere ?ith milk  prodution)

Approved

&

"# 

X

L3 (may interfere ?ith milk  prodution)

Approved

%e0onorgestrel

 "orplant1 2irena1 Plan B

2edro*yprogesterone

Pro0era1 +epo& Pro0era1 Cyrin

 "orethynodrel

:no0id

Progesterone

Crinone1 Prometrium

 

 

   

Approved

X

L2

Approved

D

L1 L4 (if used first 6 days  postpartum)

Approved

X

L2

Approved

&

L3

Cough meds 'more

'ontents

Codeine

!ylenol 761 78

 "osapine

&

 

 

Approved

C

L3

Approved

&

"# 

+eongestants 'more

Pseudoephedrine

'ontents -udafed1 Halofed1  "o0afed1 Atifed

Approved

C

+iabetes meds

L3 (for aute use) L4 (for hroni use)

'ontents

 Note: Insulin has not been reviewed by the AAP Pregnancy ris! category " #$ %actation ris! category " %& !olbutamide


 

Approved

D

+iarrhea meds

%operamide

L3

'ontents Imodium1 Pepto +iarrhea Control1 2aalo* Antidiarrheal Caplets1 Kaopetate II Caplets1 Immodium Ad0aned

Approved

B

L2

'' Note: Peto-#ismol  *aoectate (bismuth subsalicylate is the active ingredient in both) are not recommended for routine use by nursing moms+ due to the association of salicylates with ,eyes syndrome in children 'more +iuretis Aetaolamide

'ontents +aamide1 +iamo*

Bendroflumethiaide

"aturetin

Chlorothiaide

Hydrodiuril

 

Approved

   

C

L2

Approved

D

L4 (may inhibit latation)

Approved

D

L3

Chlorthalidone

Hygroton

Hydrohlorothiaide

Hydrodiuril1 :sidri*1
-pironolatone

Aldatone

     

Approved

D

L3

Approved

D

L2

Approved

D

L2

Galatagogues (milk supply) 'more +omperidone

'ontents

2otilum

 

Approved

&

Heart1 Blood Pressure meds (Antiarrhythmis1 Antihypertensi0es1 Cardia stimulants)  

'ontents

Antiarrhythmics

+isopyramide

 "orpae1  "apamide

/leainide

!amboor

2e*iletine

2e*itil

Proainamide

Pronestyl1 Proan

uinidine

uinaglute1 uinide*

 

L1

 

Approved

C

L2

Approved

C

L3

 

Approved

B

L2

 

Approved

C

L3

Approved

C

L2

Approved

D

L3 (if used after 6D days)

Approved

C

L3

Approved

C (3st trim5) D (4nd1 6rd trim5)

L2

 

Antihyertensives

Captopril

Capoten

+iltiaem=+iltiaem HC%

Cardiem -r1 +ilaor&9#1 +iltiaem1 Cardiem C+

 

:nalapril=:nalapril 2aleate

asote

Hydralaine

Apresoline

 

Approved

C

L2

%abetalol

!randate1  "ormodyne

 

Approved

C

L2

2ethyldopa

Aldomet

Approved

C

L2

2etoprolol

!oprol 9%1 %opressor 

Approved

B

L3

2ino*idil

%oniten1 2inodyl1 #ogaine

Approved

C

L2 (topially) L3 (orally)

 "adolol

Corgard1  "adolol

Approved

C

L4

 "ifedipine

Adalat1 Proardia

Approved

C

L2

 

   

   

<*prenolol

Apsolo*1 -lo?& !rasior1 !rasior 

Approved

&

"# 

Propranolol

Inderol

Approved

C

L2

-otalol

Betapae

 

Approved

B

L3

!imolol

Bloadren

 

Approved

C

L2

erapamil

Calan1 Isoptin1   Co0era&H-

Approved

C

L2

%ano*in1 %ano*iaps

Approved

C

L2

 

ardiac stimulants +igo*in

 

%a*ati0es 'more

'ontents

Casara=Casara -agrada

&

 

Approved

C

L3

+anthron

&

 

Approved

&

"# 

2agnesium sulfate

:psom salt

Approved

B

L1

-enna

&

Approved

&

L3

 

 

2alaria meds

'ontents

ChloroEuine

Aralen1 "o0o&   hloroEuine

Approved

C

L3

Hydro*yhloroEuine

PlaEuenil

 

Approved

C

L2

Pyrimethamine

+araprim

 

Approved

C

L4

uinine

uinamm

 

Approved

D

L2

2edial !esting 'more

'ontents

+iatrioate

&

 

Approved

&

"# 

/luoresein

&

 

Approved

C

L3

Gadopenteti (Gadolinium)

&

 

Approved

C

L2

Iohe*ol


Approved

B

L2

Iopanoi aid

!elepaEue

 

Approved

D

L2

2etriamide

AmipaEue

 

Approved

B

L2

2etrioate

IsopaEue

Approved

B

L2

 

 

2igraine meds (see also pain meds) 'more -umatriptan

Imitre*

'ontents  

Approved

C

-edati0es 'more

L3

'ontents

Chloral hydrate

AEuahloral1    "ote

Approved

C

L3

2ethyprylon (?ithdra?n from use in ,- . Canada)

&

 

Approved

&

"# 

Bromide

&

 

Approved

D

L5

-eobarbital

-eonal

Approved

D

L3

 

-leep Aids @olpidem=@olpidem !artrate

'ontents Ambien

 

Approved

B

-teroids

L3

'ontents

2ethylprednisolone ' high dosage methylprednisolone

-olu&2edrol1 +epo&2edrol1 2edrol

Approved

C

L2

Prednisolone

&

 

Approved

C

L2

Prednisone

+eltasone1 2etiorten1
Approved

C

L2

!hyroid meds 'more Carbimaole

'ontents &

 

2ethimaole (ati0e metabolite !apaole of arbimaole)

 

Propylthiourail

P!,

!hiourail

&

%e0othyro*ine

-ynthroid1 %e0othroid1 !hyroid1 %e0o& !1 %e0o*yl

   

Approved

D

L3

Approved

D

L3

Approved

D

L2

Approved

&

"# 

Approved

A

L1

!uberulosis meds

'ontents

Cyloserine

-eromyin

 

Approved

C

L3

:thambutol

:thambutol1 2yambutol

 

Approved

B

L2

Isoniaid

I"H1 %aniaid

Approved

C

L3

#ifampin

#ifadin1 #imatane

Approved

C

L2

   

itamins 'more

'ontents

B&3 (thiamin)

&

B&34 (Cyanoobalamin)

&

 

Approved

&

"# 

Approved

A

L1

B&F (pyrido*ine)

&

Approved

A

L2 L4 in high doses (may inhibit latation)

+1 0itamin

Califerol1 +elta&d

Approved

A

L3 (do not o0erdose)

L1

L1

/oli aid

&

 

Approved

A (3st1 4nd trim5) C (6rd trim5)

K&31 0itamin (Phytonadione)

&

 

Approved

C

#ibofla0in=B4 

&

+isetujui

A

2isellaneous

L1

'ontents

Aitretin (Anti&psoriasis)

-oriatane

+isetujui

&

"#  

Alohol=:thanol 'more

&

+isetujui

D

L3

Allopurinol

Zyloprim, Lopurin

+isetujui

C

L2

Antimony

-

+isetujui

&

"# 

Atropine (Antiholinergi1 drying agent)

Belladonna, Atropine

+isetujui

C

L3

Aapropaone=apaone (Antirheumati)

Rheumox

+isetujui

&

L2

Balofen (musle rela*ant)

Lioresal, Atrofen

+isetujui

C

L2

Barbiturate

-

+isetujui

&

"# 

Caffeine 'more

Vivarin, NoDoz, Coffee

+isetujui

B

L2

Carbetoin (Antihemorrhagi)

Duratoin

+isetujui

&

"# 

Chloroform

-

+isetujui

&

"# 

Cisplatin (Anti&aner)

!latinol

+isetujui

D

L4

+apsone (Antileprosy)

Avlosulfon, DD"

C

L4

+isetujui

Hydro*yhloroEuine (Antirheumati1 lupus)

!la#uenil

+isetujui

C

L2

Iodides

-

+isetujui

&

"# 

Iodine

-

+isetujui

&

"# 

Iodine (po0idone&iodine1 eg1 in a 0aginal douhe)

+isetujui

&

"# 

I0ermetin (Antiparasiti)

$etizan

+isetujui

C

L3

 "alidi*i aid (,rinary Anti& infeti0e)

Ne%&ram

+isetujui

B

L4

 "orsteroids

-

+isetujui

&

"# 

Pyridostigmine (2usle stimulant)

$estinon, Re%onol

+isetujui

C

L2

-opolamine (2otion sikness)

'ransderm "ope

+isetujui

C

L3

-ulfapyridine

Da%enan

+isetujui

&

"# 

!imolol (glauoma med)

Bloadren

+isetujui

D

L3

$ Per the AAP Poliy -tatement !he !ransfer of +rugs and ith Breastfeeding   Cation (!able ) +rugs !hat Ha0e Been Assoiated >ith -ignifiant :ffets on -ome "ursing Infants and -hould Be Gi0en to "ursing 2others >ith Caution • •

•

 "# "ot #e0ie?ed5 !his drug has not yet been re0ie?ed by the AAP5

$$ Per .edications/ and .others/ .il!  by !homas Hale1 Ph+ (4DD8 edition)5 Lactation Risk Categories

Pregnancy Risk Categories

•

L1 (Paling Aman)

•

A (studi terkontrol menunjukkan tanpa resiko )

•

L2 (Aman)

•

B (tidak ada bukti risiko pada manusia)

•

L3 (Cukup Aman)

•

C (risiko tidak dapat dikesampingkan)

•

L4 (Kemungkinan Barbahaya)

•

D (bukti positif resiko)

•

L5 (Kontra Indikasi)

•

X (dikontraindikasikan untuk Ibu Hamil)

 "# "ot #e0ie?ed5 !his drug has