ATENEO DE MANILA UNIVERSITY SCHOOL OF SCIENCE AND ENGINEERING Department of Biology Loyola Heights, Quezon City, Philippines 1108 Telephone No. +63(2)426-6001 ext. 5610
Course Number: Bi 149 A Title: Cell & Molecular Biology, Lecture Department: Biology Department, School of Science and Engineering, Ateneo De Manila University School Year/Semester: 2013-2014, 2nd Semester Instructor: Zomesh A. Nath Maini, M.Sc.
A. Course Description This course is an introduction to cell and molecular biology that discusses the structure and function of the different components of the cell at the molecular level as well as the interactions among cells. In addition, the fundamental principles on structure and organization of genes will be examined including gene expression and regulation. B. Number of Units 3 units C. Course Objectives At the end of this course, the students should be able to: differentiate between the prokaryotes and eukaryotes; identify and characterize the different chemical component of the cells; describe the gene structure and organization; understand DNA replication, transcription and translation; describe the structural organization and functions of the cellular constituents; 6. relate structure to function and understand cellular interactions; and 7. appreciate the mechanisms of cellular immunity and carcinogenesis. 1. 2. 3. 4. 5.
D. Course Outline and Timeframe (May change depending on pace)
E.
Week 1-3
Introduction: Syllabus Overview of the Cell Universal features and Evolution of the Cell Prokaryotic and Eukaryotic Cells Cellular Biochemistry Important Biomolecules Cellular Macromolecules
Week 4-6
Exam `1 Cell Physiology: the Cell Membrane Endomembrane Transport Membrane transport Intracellular Compartmentalization Vesicular Traffic
Week 7-9
Exam 2 Bioenergetics Mitochondria Chloroplasts Cell Communication: Signal Transduction Mitosis and Meiosis
Week 10-12
Exam 3 Cell Nucleus and Gene Expression DNA and Chromosome Organization The Central Dogma: Replication, Transcription, Translation Regulation and Gene Expression
Week 13-16
Exam 4 Special Topics Mechanisms of Development Cancer The Immune System
Exam Week
Final Examination
Suggested Readings Alberts B., Bray, D., Lewis J., Raff, M., Roberts, K., Watson, J.D. Molecular Biology of the Cell, th 5 Edition. Garland Publlishing, Inc., NY, London. Lodish, H., Berk, A., Zipursky, L., Matsudaira, P., Baltimore, D., Darnell, J., Molecular Cell th Biology, 4 Edition. W.H. Freeman, NY. th
Karp, G. Cell and Molecular Biology, Concepts and Experiments, 5 Edition, john Wiley and Sons, NY F.
Course Requirements Long Exams Reporting Class Participation Final Examination
G. Grading System 60% 10% 10% 20%
91.5-100 86.5-91.4 79.5-86.4 74.5-79.4 67.5-74.4 59.5-67.4 below-59.4
A B+ B C+ C D F
H. Classroom Policies 1. 2. 3.
4. 5. 6. 7. I.
Students are allowed to cut a maximum 6 lecture sessions. Any cut in excess of the maximum will result in a grade of W (withdrawal from the course without permission). Students who arrive beyond 20 minutes after the start of the session will be marked absent. Three late arrivals (within first 20 minutes of session) will be considered one cut. If the instructor does not arrive within 10 minutes after the official start of class, the class beadle should ask at the Biology Department (SEC-A 105) for an official announcement unless the teacher has already informed the class beadle. All mobile phones are to be turned off or set to silent mode during the class. Cheating is a major offense and shall be dealt with severely. Make-up exams will only be given to students with valid and verifiable reasons. Any other announcements shall be given in class as necessary.
Consultation Hours MW 8:30am-10:30am, SEC-A 105 (Biology Department), or by appointment.
J.
Contact Details Office Line: 426-6001 loc. 5610 to 5611 Mobile: 0917-8966374 Email:
[email protected],
[email protected],
[email protected]
