1. Which Which of of the fol follow lowing ing sta statem tement ents s concer concernin ning g the anti anti-in -infla flamm mmato atory ry effe effect ct of NSAIDs are TRUE? a) Anti-inflammatory effect of NSAIDs results from inhibition of cyclooxygenase cyclooxygenase b) Anti-inflammatory effect of NSAIDs results from inhibition of phospholipase phospholipase A2 and reducing prostaglandin and leukotriene synthesis c) Anti-inflammatory effect of NSAIDs results from induction of cyclooxygenase II expression which results in reducing the amount of an enzyme available to produce prostoglandins d) All of the above above 2.
Which Which of the follo followin wing g NSAI NSAIDs Ds is a sele selecti ctive ve COX-2 COX-2 inhibi inhibitor tor? ? a) Piroxi Piroxicam cam b) Indomethac Indomethacin in c) Celeco Celecoxib xib d) Diclofe Diclofenac nac
3.
Which Which of the follo followin wing g NSAID NSAIDs s is is a nonsel nonselect ective ive COX inhibi inhibitor tor a) Piroxi Piroxicam cam b) Rofeco Rofecoxib xib c) Celeco Celecoxib xib d) All of the above above
4.
The follow following ing statem statement ents s conc concern erning ing aspir aspirin in are true, true, EXCEPT EXCEPT:: a) In contrast to most other NSAIDs, aspirin irreversibly inhibits COX b) Aspirin interferes with the chemical chemical mediators of the kallikrein system system c) Aspirin Aspirin inhibits phospholip phospholipase ase A2 d) Aspirin inhibits tromboxane A2 formation
5.
Indica Indicatio tion n for for aspi aspirin rin admini administr strati ation on are are the the fol follow lowing ing,, EXCEP EXCEPT: T: a) Inflammator Inflammatory y conditions b) Decreasing the incidence of transient transient ischemic attack, unstable angina, coronary artery artery thrombosis with myocardial infarction, and thrombosis after coronary artery bypass grafting c) Relieving severe severe visceral pain( myocardial infarction, cancer pain condition, renal or biliary colic ) d) Reducing elevated elevated body temperature
