KELOMPOK 1 (Monitoring Biologis)

MONITORIN #IOL #IOLOIS OIS

A N R I M A RI O T U A 1 3 1 00 0 1 4 9 DYA H E KA P U T R I 1 3 1 00 0 2 5 0 E LV A R O S A L I A S Y A H R I A L 1 3 1 0 0 0 6 7 7 F RI SC A I RAWA N 1 31 00 00 54 I LV I L I AN S U R I 131000264  J U N I M A N S A  A L A 1310001!! N A DYA F I T R I H A N D A N I 1 3 1 0 00 4 1 4 N A N A R I" K Y F I T R I A 1 3 1 00 0 0 93 V ERY #A S T I A N 131000211

DEFINISI MONITORIN #IOLOIS

M$%&'$(&%) *&$+$)&, -.-+-/ mengukur dan mengases  ,-' -' &&- -'- '-*$+&'%- .-+- -(&%)-% sekreta, ekskreta, udara ekspirasi atau kombinasi .-(& 8-.-%)%%)-+-,& '&%)-' paparan dan risiko '(/-.-8 kesehatan -%) .&8(*-%.&%)-% '(/-.-8 (:(%,& -%) '8-' ;/&8(, .-% ,+--'-% (-<=

 JENIS MONITORIN #IOLOIS

-= M$%&'$(&%) *&$+$)& : M$%&'$(&%) *&$+$)& .-(& : '$,&-% ;/-+'/ ,(&++-%><= T-% $%&'$(&%) *&$+$)& .-(& : '$,&-% -.-+-/ memprediksi dosis internal %' %&+-& hubungannya  .%)-% mengevaluasi status (&,&$ ,/-'-% kesehatan .-(& &%.&&. -%) '(8-8-( .-% mengidentifkasi tanda eek negati   -&*-' ,-' 8-8-(-% &,-+%- +-&%-% :%),& 8-(=

*= M$%&'$(&%) -*&% M$%&'$(&%) -*&% %' menilai  (&,&$ ,/-'-%= M$%&'$(&%) -*&% '(,*' memonitor paparan .&)%--% %' eksternal .-(& *-/-% &&- %' %)'-/& *(-8- kadar bahan kimia .& .-+- -&( --%-% .-% .-(-= R&,&$ ,/-'-% .-8-' .&8(&(--% ;.&8(.&,&< *(.-,-(-% batas paparan lingkungan &,-+%- Treshold Limit Value (TLV) dan Time Weighted Average (TWA) .-(& ,-' 8-8-(-%=

>= M$%&'$(&%) *&$+$)& 8-8-(-% M$%&'$(&%) *&$+$)& .-(& 8-8-(-% ;M# 8-8-(-%<= M$%&'$(&%) *&$+$)& ,-' 8-8-(-% -.-+-/ pemantauan  ,-' *-/-% -%) %)-.--% penetrasi   .-+- '*/ .%)-% eek sistemik  -%) membahayakan = M$%&'$(&%) *&$+$)& .-(& ,-' 8-8-(-% .-8-' .&8--& %' mengevaluasi (&,&$ ,/-'-%= M$%&'$(&%) *&$+$)& '(,*' dilaksanakan  .%)-% memonitor dosis internal .-(& *-/-% &&- &,-+%- +-/ .$,&, :'&: -%) .&,(-8 $+/ $()-%&,= R&,&$ '(/-.-8 ,/-'-% .&8(.&,& .%)-% *-%.&%)-% nilai observasi dari parameter biologi   .%)-% Biologial Limit Value (BLV) dan!atau Biologial "#posure $nde# (B"$)=

MACAM?MACAM MONITORIN #IOLOIS 1= #&$$%&'$(&%) L$)- #&$$%&'$(&%) +$)- .-8-' .&+--% .%)-% pemeriksaan  ,-' .&- %' menentukan bahan logam= M.&- -%) .&8--& -%'-(.-(-/@(&% -(&%)-% '*/ &-% *&%-'-%) &%('*(-'- .-% '-%--% 8(-&(-%= -= L$)- -%) .-8-' .&'-% 8-.- .-(-/@(&%  C-.& "-' *,& M-%)-%, T*-)- M((& "&% *= L$)- *(-' .& -'$,:( -%) .&'-% 8-.- -(&%)-% *(%)  8-('&+ '&*-+ C-.& A(,% M((&= >= L$)- *(-' .& 8(-&(-% -%) .&'-% 8-.- &-% C/($&  T*-)- T&*-+ "&%= L$)- '(,*' --% %&%)-' -.-(%- -8-*&+- -.- 8%&%)-'-% #OD .& 8(-&(-%= .= L$)- *(-' .& 8(-&(-% -%) .&'-% 8-.- *&%-'-%) &%('*(-'- C/($& C-.& '*-)- '&*-+ >$*-+' %&+= =  T-%--% 8(-&(-% .-% '-%--% .-(-' .-8-' .&8--& ,*-)-& bio indikator lingkungan -%) terkontaminasi $+/ logam berat= P-*(& 8%)>$(-% *,& -%) %)+-(-% *-/-% 8%>-( .-(- +$)- *(-' .-8-' .&.',& 8-.- '-%--% .%)-% -%-+&,&, N'($% A>'&-'&

%$ 2= #&$$%&'$(&%) "-' O()-%& A+-,& -' $()-%& 8-.- **(-8- spesies mamalia (8--% bio indikator  -%) 8$'%,&-+ %' mendeteksi penemaran lingkungan = #*(-8- -' $()-%& -%) .&8--& &%.&-'$( -%'-(- +-&% -= 8(*-/-% %$% 8($'&% ,+:/&.(&+ 8-.- ,+ +&( .-(& '&, ,*-)-& &%.&-'$( '(8-8-( $+/ 8,'&,&.-= *= M%&%)-'%- *&+&(*&% 8-.- '&, %%-% -.-%- 8-8-(-% $+/ T(& N&'($ T$+% ;TNT<= >=  T(.-8-'%- /*%)-% -%'-(- 8%>-(-% +&%)%)-% .%)-% P$+ C/+$(&%-'. #&:%&+ ;PC#< .&$B&% .-% :(-% 8-.- -%,&-= .= T(.-8-'%- .&$B&% :(-% PC# DDE .-% +&%.-% 8-.- '+( *(%) ,*-)-& &%.&-'$( '(>-(%- +&%)%)-% $+/ -' $()-%& = T(-+-,&%- PC# 8,'&,&.- .-% *-/-% -%'($8$)%& 8-.- '*/ &-% ,*-)-& &%.&-'$( '(>-(%- $,&,' 8(-&(-% := M%&%)-'%- -'&'-, M&B. F%>'&$% OB&.-, ;MFO< 8-.- &-% .& ,%)-& -%) '(>-( $+/ *-/-% $()-%& PAH D&$B&% .-% PC#= )= A'&&'-, %$*&$'&  DNA -..>' C'$>/($ P 450 &%.,& .-% $(+ /&.($-(*$% /&.($,&+-, 8-.- &-% .&8--& ,*-)-& *&$-(( 8%>-(-% 8-%'-& $+/ PC# .-% DDT= /= M%)(-%)%$%&'-, 8/'$8+-%'$% .-8-' .&8--& ,*-)-& *&$$%&'$(&%) 8%>-(-% 8,'&,&.- .-+- 8(-&(-%=

3= #&$$%&'$(&%) L&*-/ C-&( A.- **(-8- ,'.& '$,&,&'-, -%) .&8--& %' %&+-& *-%)-% +&*-/ >-&( -%'-(- +-&% 8--&-% *-'(& .-% 8--&-% &%('*(-'-= L&*-/ 8-*(& ('-, -%) %)-%.%) *-/-% &&8'&/ .&+--% ,'.& --& *&$'- -&( &,-+%- &-%= C-(- *-( %' %&+-& -+&'-, -&( +-' -%) '($%'-&%-,& $+/ *-/-% &&- 8'&/ -.-+-/ .%)-% >-(- *&$ -,,- -%'-(- +-&%  & &%/&*&,& 8('*/-% -+)- .-% & +-(- *&$'- -&(= 4= #&$$%&'$(&%) P%>-( U.-(P(*-/-% -*&% -'$,:( $+/ -.-%- *-/-% 8%>-( .-(--% .-8-' 8%)-(/& /&.8-% '-%--%= D-% 8&%, -( .-8-' .&8--& ,*-)-& &%.&-'$( 8%>-(-% -+&:-'& /&.($-(*$%= D%)-% 8(&,--% )-, ($-'$)(- .&'-% *-/- -.-( /&.($-(*$% +*&/ '&%))& 8-.- .-% 8$/$% 8&%, -%) *(( '-=  T-%--% '&%)-' (%.-/ -%'-(- +-&% +&>/% 8-(-+&- ,+>-'- .-8-' ,*-)-& &%.&-'$( 8%>-(-% .-(-= D%)-% .&&-% -- +&>/% .-8-' .&8--& ,*-)-& *&$$%&'$( %' 8%>-( .-(-=

5= #&$$%&'$(&%) A,&.&-,& P(-&(-% -%) 8%-& 8H (%.-/ --% *(,&:-' -,-= K-,--% 8(-&(-% .-8-' .&.',& .%)-% --& *&$-(( *&$'- -%) /&.8 .-+- 8(-&(-% '(,*'= D-+- -.--% 8H (%.-/ ;8HG3< -- +$)- *,& .-% -%)-%, --% '(.',& .-+- 8(-&(-%= E: 8(-&(-% .%)-% 8H (%.-/ +$)- -%) '$,&, .-% D&,,$+ O()-%&> C-(*$% ;DOC< '(/-.-8 /-% -*& --% %*-*-% '(+-*-'%- '-$(:$,- %(%%- .-- '-/-% .-% %(%%- *(-' *-.-% /-% -*&= 6= #&$$%&'$(&%) K,/-'-% M-%,&#&$$%&'$(&%) P* .-% C. 8-.- -%&'- -%) +-/&(-% .&+--% .%)-% 8(&,--% ASI .-% .-(-/= K-(--% &%.,'(& 8'($&&- -%) '(8-8-( .%)-% PAH 8-.8(&,--% (&% .&'-% *&$-(( /&.($,&8(%=

KLASIFIKASI MONITORIN #IOLOIS 1= D'(&%-,& -' &&- -'- '-*$+&, .-+- .&*&$+$)&, -'- .-(- -%) .&/*,-% +-+& 8(%-:-,-% >$%'$/ C-.& .-+- +&( .-% &.% ,('- +-. .-+- '+-%) .& $%&'$( %))%--% %'($ ->'&-'&$% -%-+&,,@?(- $(,>%>= 2= K-%'&-,& : *&$+$)&, -%) *(/*%)-% .%)-% .$,&, &%'(%-+ >$%'$/ ',' -'&&'-, >/$+&%,'(-, .-+- ,( %' %)-,, 8-8-(-% $()-%$8$,8-'= 3= P%)(-% +-/ -' &&- -%) ,>-(- -'&: *(&%'(-,& .%)-% '-()' $()-% .-% %$%?'-()' ;,(($)-'< $++ >$%'$/ ',' &%$+$)& -'- '%& C?MS &,-+ /-,&+ 8%(%-% DNA .-(& >-&(-% '*/=

UJI MONITORIN #IOLOIS -= U& ,+'&:  U%' %)& *-/-% &&- -%) '&.- %)-+-& *&$ '(-%,:$(-,& ,8('& *-/-% &&&% $()-%&> U%' *-/-% &&- $()-%& *&-,-%>8-' .&'-*$+&,&(  +*&/ .-/ +-(' .-+- -&( ,/&%))- .-/ .&+-(-% +-+& (&% -'- 8.= K%'%)-% ,-8+ (&% -.-+- .-/ .&8+-% ,'&-8 ,--' *&-,-%- -/&( (- ,/&:' .-% '-*$+&' .-+- (&% (-%) .&8%)-(/& $+/ 8-8-(-% ,'(%-+ +-&%=

*= U& %$% ,+'&:  U%' &%.&-'$( %$% ,8('&,& .-(& 8-8-(-% *-/-% &&- ,*-)-& >$%'$/  1= P%%'-% '-*$+&' .&-$ 8$,&'&: .& .-+- (&%= U& &%& %' $%&'$(&%) 8-8-(-% -($-'& -&%= 2= A%-+&,&, '/&$ '/( .-+- (&%= U%' $%&'$(&%) *-/-% -(,&$)%&> .-% -%'&)%&> -%) *(,&:-' +'($+& .& '8-' (-= R$$ -.-+- :-'$( $%:$%.&%) -.-%- '/&$ '/( .-+- (&% 3= P%%'-% -'&'-, '-)%& .& .-+- (&%= P%&%)-'-% -'&'-, '-)%& .& .-+- (&%= P%&%)-'-% -'&'-, '-)%& .-+- (&% '.-8-' 8(- 8-*(& -(' 8-*(& *-- .-% -/+& -%-,',& ,('- 8(--' -%) %)+$+- $*-' ,&'$,'-'&= P-.8($$ )- '.8 8%&%)-'-% -'&'-, '-)%&

MEDIA MONITORIN #IOLOIS I%.&-'$( *&$+$)&, -.-+-/ -' &&- .-+- .&- *&$+$)&, -%) (8--% 8'% .-(& -' &&- -%) '(/-.-8%- '%-)(- '(8-8-(= M.&- *&$+$)&, .&&-% .-(-/ +%)-8 8+-,- -&( +&( (&% (-*' )&)& ,, .-(- -+$+, .-% *&$8,& '+-%)= D-(-/ -'- (&% -.-+-/ .&- '(*-& %' 8(+-% $%&'$(&%) *&$+$)&, '(-.-8 8-8-(-%= "-' &&- -'- '-*$+&'%- .-+- '&%- -&( +&( (&%)-' .-% ,*-)-&%- /-%*(&-% )-*-(-% .%)-% +&%)8 ,-%)-' '(*-'-, '%'-%) -.--% 8-8-(-% '(/-.-8 -' '(,*'= P-.- %- (&% .&8--& ,*-)-& .&- %' %)( *-/-% &&- -%$()-%& .-% $()-%& -%) .-/ +-(' .-+- -&(= D-(-/ .&8--& ,*-)-& .&- %' ,*-)&-% *,-( *-/-% &&-%$()-%& .-% $()-%& -%) ,-( .&+--% *&$'(-%,:$(-,& ,.-%)-% .-(- -+$+, .&8--& %' *-/-% -%) .-/ %)-8=

 TUJUAN MONITORIN #IOLOIS S>-(-  '-% .-(& )&-'-% 8-%'--% *&$+$)& -.-+-/ ,-- .%)-% 8-%'--% -*&% -&' %>)-/ '(-.&%- 8-8-(-% *-/-% &&-%) .-8-' %*-*-% )-%))-% ,/-'-% *-& ,>-(- -' -8% ($%&,= P-.- '-/-8 --+ '-%%- &-+-/ %' %)&(-? %)&(- '&%)-'-% %)%-& -' &&- ,&%''&, .-% *-'-% 8-.- -(&%)-% -%,&- .-% >-&(-% ,--' &%& .-% %.&--% .-'- -%) .&)%--% %' 8%)-*&+-% 8',-% %)%-& *'/-% 8%+&'&-% -%) --% .-'-%)=

MANFAAT MONITORIN #IOLOIS #&$$%&'$(&%) %.&--% &%:$(-,& -%) *&,.&)%--% .-+- *(*-)-& >-(-= D-'- &%& *-%' -/-& -' -%- -%) -.- .& +&%)%)-% .-% '&%)-'-% (+-'&: -,&%)?-,&%) *-)-&-%'&%)-'-% &%& *(*-/ ,&(&%) .%)-% -' .-% ,'$( -%- 8-.- 8$8+-,& -%) &+&& 8-8-(-% '&%))& -%) '&.- *&-,- '(/-.-8 ,%-- '('%'= S*-)-& /-,& .-(& 8-/--% &%& %)&% *&,-  1= M%-,&( :'&:-% '-/-8 -%) .&-*&+ %' %)(-%)& 8-8-(-%= 2= M%)&.%'&-,& 8%+&'&-% *-( -%) .&*'/-% 3= M*-%' .$'( %.&-)%$,- .-% %)$*-'& 8-,&% -%) %)&% &+&& 8-8-(-% '&%))& -%) '&.- *&-,'(/-.-8 ,-' -' '('%'=

HAL?HAL YAN DIPERHATIKAN DALAM MONITORIN #IOLOIS #*(-8- :-'$( -%) /-(, .&8(/-'&-% .-+- 8%)(-% ,-' 8-(-'( .-% -' 8%)-*&+-% ,-8+ -.-+-/ S&:-' ,&$?&&- .-(& *-/-% K$%.&,& 8-8-(-% P-(-'( '$,$&%'&  .&,'(&*,& *&$'(-%,:$(-,& .-% +&&%-,& S%,&'&&'-, .-(& '$. -%-+&,&, -%))-% ,/-'-% D$,&, $()-% ;*,-( .$,&, 8-.- $()-%< D$,&, '-()' ;*,-( .$,&, 8-.- ,-,-(-%< •

•

•

•

•

•

•

K'(+-,-%--% ;:-,&*&+&'< $%&'$(&%) *&$+$)&, .&'%'-% $+/ -.-&%8%)'-/-% '%'-%) '$,&$&%'&- .-% '-*$+&, -' -%) '(/-.-8%- $%&'$(&%) *&$+$)&, .&+--% .&8%/&%- 8(,-(-'-% -,8 8(-'&, 8%)-*&+-% ,-8+ .-% -%-+&,&, -%) '&.- (&' -(-' .-% '&.- -/-+ .-8-' .&'(&-%- >-(- 8%)-*&+-% ,-8+ $+/ '%-)- (- ,('- >-(- '(,*' '&.- *-/---% '%-)(-%) *(,-)'-%=

P(,-(-'-% *-)& *(/-,&+-% ;,>>,,< $%&'$(&%) *&$+$)&, %>-8 *(-.--% -' &&- -'- '-*$+&'%- .-+- -(&%)-% >-&(-% '*/ -'- ,(,& -%) >$>$ %' .&-*&+ ,-8+%- -.-%- '$.- -%) -+&. .-% 8(-'&, *-)& .&+--%%- 8%)-*&+-% .-% -%-+&,&, .&- *&$+$)&, ,'(-')& 8%)(-% -%) *-& ,.-%)-% ,-8+ (8(,%'-'&: .-% '(/-.-8 /-,&+ $%&'$(&%) *&$+$)&, .-8-' .&*(&-% &%'(8('-,& -%) *(-('&=

NILAI STANDAR ;IP#< I%., P--%-% #&$+$)&, ;IP#< -.-+-/ 8.$-% %' %&+-& /-,&+ $%&'$(&%) *&$+$)&,= IP# %%-% ++ .-(& .'(&%-% -%) .&$*,(-,& 8-.- $+,& ,8,&% 8(- ,/-' -%) '(8--% *-/-% &&8-.- -.-( -%) ,-- .%)-% 8(- '(%- 8--%-% &%/-+-,& *-/-% &&-= IP# ,>-(- '&.- +-%),%) %))-*-(-% .$,&, 8--%-% *-/-% &&- -%) .&'(&- 8(-= D'(&%-% IP# *&,- *(8- *-/-% &&- &' ,%.&(& -'- /-,&+ '-*$+&, -%,&-= H-,&+ '-*$+&, -%,&- -%) *&-,- .&-.&-% ,8,&% .& -%'-(-%- -.-+-/ (&% .-(-/ .-(- ,/-+-,&= F%),& .-(& IP# -.-+-/ %' *(&-% &%:$(-,& 8-.- -/+& ,/-'-% (- .-+- %.',& .-% %%'-% -*,$(*,& *-/-% &&- +-' 8--%-% +&' ,&,' )-,'($&%','&%-+ .-% &%/-+-,&= S+-&% &' IP# ).&)%--% %' M%&+-& **-% '*/ -&*-' 8--%-% *-/-% &&M($%,'(,& 8--%-% -,- +-+ 8-.- 8%)(-% /-.&(-% 8--%-% +-&% M%.',& -.-%- 8--%-% *-% -(%- -&*-' (M%&+-& *(/-,&+-% 8($)(- $%'($+ '%& .-% 8%))%--% 8(,$%-+ 8($'>'& &8%' 8-.- 8(•

•

•

•

WAKTU PENAM#ILAN SAMPEL W-' 8-(/ ,-' -' &&- )- 8%)-(/& 8(&,--%= E,(,& -' 8-(/%- 8-%-%) -.-+-/ )-*-(-% ,&*-%)-% -' *(,-%)'-% .-+- .-(-/ ,/&%))- ,-8+ .&-*&+ ,-' -+& ,*-(-%) -'=  Y-%) .&-,. .%)-% -' 8-(/ 8-%-%) -.-+-/ .-(& **(-8- *+-% ,-8-& *+-,-% '-/%= C$%'$/%-  '&*-+ ;P*< >-.& ;C.< -&( (-,- ;H)<= P%)-*&+-% ,-8+ %' -' 8-(/ *+-,-% - ,-8-& ,-'?.- *+-% >8 .&+--% 8-.- -/&( 8-,>- ,/&:'= C$%'$/%-  -(,% ;A(< ($& ;C(< $*-+' ;C$< %&+ ;N&<= P%)-*&+-% ,-8+ %' -' 8-(/ +*&/ .-(& ,-' ,-8-& **(-8- - .&-*&+ ,)(- %)&% 8-.- -/&( ,/&:'= C$%'$/%-  ,'&(% *%% ;C6H6< -(*$% $%$,&.;CO< -(*$% .&,+. ;CS2< '(&+$('-%=

 TERIMA KASIH

DAFTAR PUSTAKA •

•

•

/''8@@.(?,8-(-%'$=*+$),8$'=>$=&.@2011@09@*&$ $%&'$(&%)=/'+G1 /''8,@@:-./&+/--'=$(.8(,,=>$@2010@12@23@*&$ $%&'$(&%)?*&$-((?+&%)%)-%@ P=K S-(= Higiene Perusahaan dan Kesehatan Kerja (HIPERKES). J--('-  S-)%) S'$ 2013=