Makalah Patofisiologi Infark Miokard

!%$## !%$ ## 

&%$#$ &'#$%$$& $$# 

%!%# !: 8::7 05,/, %:,3  ,703, -07,9 7,2,9, ,2 /,5,9 203008,,3 2,,, 03,3 :/:31,7 4,7/ :9, /,5:3 2,,, 3 /8:8:3 :39: 20203: 9:,8503:3,35,/,:,5,941844 !,/,08025,9,335:,503:8:3203,25,,39072,,880-08,7-08,73,05,/, /74%,:1$5! 80,: 502-2-3 ,2 !03:8:3 203,/,7 -,, /,,2 503:8:3,3 2,,,2,8-,3,907/,5,90:7,3,32,,80,,79/,38,7,3202-,3:3/,75,7,  502-,.,8,3,9,2,7,5,3/0208025:73,,32,,,3 7,9,503:8:3203:.,5,39072,,88024,2,,,3-072,31,,9-,9, 802:,

!&& 31,7 24,7/ -,8,3, /80-,-,3 40 9742-:8 ,7907 474307%07,/3, 9742-:8 /80-,-,3 40 7:59:7 5, ,3 02:/,3 /:9 40 502-039:,3 9742-:8 /,3 9742-4894,8/,3:,83,24,7/31,7907,39:35,/,,7907,34:8/,3,7,3/,7, 4,907,:8 ,7907 4743,7, -8, :, 9/, 8,25, 2032-:,3 31,7 -, /,07, ,3 /507/,7,,7907,34:890780-:9203/,5,95,84404,907,502-::,7907,33,  ,2:3 /02,3 503/079, /03,3  03/,3, 8007, 203/,5,9 5079443,3 40 ,703,,3,02,9,38,3,993907:9,2,/,,2,2,25079,2,807,3,3/,5:31,947 1,947,32025072:/,907,/3,,39,7,,32074450790384-089,8 3/4308,80, 805:: 9,:3907,7 0- 8073 /902:,3,5,, /03,3 ,/,3, 1,89,8 /,3489. /,3 :39:39 507,,9,3 503,9 ,39:3 474307 ,3 802,3 90780-,7 207,9,02,:,3 /,,2 5034-,9,3  / :39 507,,9,3 ,39:3 474307 390381  -07,8203:7:3,3,3,02,9,3



0138

31,7 4,7/ :9 ,/,, 307488 24,7/ ,-,9 ,7,3 /,7,0 4949 ,39:3 ,3 907,3:, 3 -8, /80-,-,3 9742-:8 ,7907 474307 40 7:59:7 5, ,3 /5072:/, 907,/3,401,9471,947805079507903820744/,3507408907402, 944

%07,/3, 31,7 4,7/ :9 -,8,3, /,703,,3 ,9074807488 502-:: /,7, 4743070748824,7/,:9907,/,-,9503:2-,9,3949,,79074743,7,409742-:8 ,3907-039:5,/,5,,9074807488,39/,89,-:,8073203:97:59:75,5,/, ,7907.474307/03,3890348873,3,9471,947,32025072:/,907,/3,,39,7, ,32074450790384-089,8507408907402, ,-0908 09:8 057-,/,3

,3

30:749 !,941844

31,7 4,7/ ,3 /80-,-,3 9742-:8 ,7907 474307 /,5,9 20303, 03/4,7/:2 8,25, 05,7/:2/80-:9 31,7 97,382:7,3,2:3 -8, :, ,3, 20303, /,07, 8:-03/4,7/,/80-:931,78:-03/4,7/,$090,2039907,/3,8:2-,9,331,78:/, /,5,9 907,/ 5,/, 8:-03/4,7/:2/,3 -, -07,3:9 907:8 7,9,7,9, /,,2  ,2 90, 907,/ 31,797,382:7,07:8,,324,7/ 3 /,7 03/4,7/:20 05,7/:2203,/4259 /,3 70;078-0/,,2,2085:330748824,7/8:/,42595748087024/0324,7/ ,3203,,23:7907:8-07,3:98,25,-0-07,5,23:,9,: -:,3,703,/,07,31,7 20:,8/,3/,07,34331,7203,,2/,9,8 0,,38

0:,3 :9,2, ,/,, 8,9 /,/, ,3 907:9,2, /7,8,,3 / /,07, 89073:2-8, 203,,7 0/,/, 7 ,9,: ,3,30 7,,30 -,: 7 /,3,3,3 /,3 5,/, 03,3!03/079, 20:8,380507990790,3907259/702,8702,8,9,:,/,3,3,80-,,7,8,9/,03, //,/,,,:81,93,/,5,973,39,57,8,8,99:-,8,3,-07,38:30-/,780903,  ,2,7,3,/,:-:3,33,/03,3,919,88079,9/,,3/03,3897,,9,9,:502-07,3 397,9!,/,80:2,503/079,/,5,992-:-07-,,503:9,792,703,9,3,7/403,,  ,39:3

,3488

3,23088 /,3, 307 /,/, ,3 ,2,3, 0- /,7  2039 / /,07, 57047/,7097489073, /,3 203,,7 0 03,3 703,3 ,3,3 /,3 0 -0,,3 39078,5:07#,8, 307 805079 /.0,2/702,8702,890793/-03/,5,/,99079:8:58,:,9,:805079907-,,7,/,3,/,3 7,8,307 9/,,/, /,3 503/079, ,3, 2030: 02,-,3,073,95:835,59,8/,3  507,8,,3,,32,9 !02078,,318 !03/079, 3,25, 8,92:, 5:.,9:9 -,8, /,3 /33%0,3,3 /,7, -8, 933472, ,9,: 703/,,5,9 /902: -:3 ,39:3 0/:, ,3 50., 5,7,/48,7,2, ,45,/,3,/,3 /902:,3 5:8,8 /8309 ,3 9,25, ,9,: 907,-, / /3/3 /,/,  5,/,310747  !,/,907/,5,9,2-,7,3042-,3",35,94488079,507:-,,380203$%% /2,3,907/,5,9$%00;,8$%/05708/,3%907-,,9,2-,7 !02078,,3,-47,947:2 /,3, 5033,9,3 032$%!,9 ,2-,7 5,-, 907/,5,9 /,7  0,,90780-:9/,9,82,,/,3480/,7/,5,9/90,,3 ,3480,3/3 33,!094789/,89,-38:18038474307,:9 !,/, 43/8 3 ,33, /,5,9 -07,38:3 ,2, 909,5  ,3, 202507,9,3 /05708 80203 $% 9,35,/8079, 042-,3 " ,3 5,9448 /,3 9,35,/8079, 5033,9,3 032 808,479,  07 /,/, /83 :2:23, ,2,9 0-,9 /,5,9 203,,7 0 507:9 /,3 5:3:33,/  507107 /,5,9 ,820978 /,3 /,5,9 /902:,3 -83 /,894. /3 / 5,7,89073, 7!,/, 1494 743903/,/,9,25,500-,7,320/,893:2 0,3,38,:7,3.073,-,,3,9,8073,/,17,2,9,0841,98 701:8  07 -07,9,3 /03,3 2,,3,3 /,3 .03/077:3 92-: 5,/, ,9: 9/:7,/,3 ,/,3/902:,334385081

0,3,34,/3/3/,/,  07:2:23,809025,9-079,2-,/03,390,3,3,9,:507:-,,354889:-: 4257088,7,1907:9,2,  07907/,5,95,/,/897-:88,7,190780-:9 0,3,3397,,-/423, 0,3,3,:9,9,:5,370,9989,35,20307:5, !03,9,,8,3,,3 !034-,9,3 /9::,3 :39: 80/,5,9 2:33 202507-, 02-, ,7,3 502-:: 474307 803, 705071:8 /,5,9 203.0, 07:8,,3 24,7/ 0- ,3:9 8079, 203.0, 02,9,3 203/,/, /03,3 202,39,: /,3 2034-,9 ,792, 2,3,/,3, 4-,94-,9 9742-488 ,3 /,5,9 /-07,3 80-0:2 /-,, 0 7:2, 8,9/,5,9 203:7:3,3 ,3, 02,9,3 80-08,7 -,9 ,3 /5,, ,, 89705943,80 /03,3 .,7, 502-07,3  :9, :3989705943,80/,79,3/,,22/089748,/-07,3 397,;03,80,2,,2!07,,9,3,39,7,,3 !07,,9,3390381/,324-8,8 !03/079, -07897,,9 /,3 /-07,3 /09 2,,3,3 :3, 8079, ,3,3 907,: 5,3,8 ,9,: /33,507:/-07,34-,94-,950303,3 03,9,8307 -,95,3:39:3075,/,,/,,247530/488 2;-,9/,,/,/,5,9/,39 20507/30/03,3/48822!705,7,9397,98:-3:,,9,:47, !02-07,3 &39:80/9203,2-,4803,824,7/ !743488 !,/,0584/002,9,3907,/203/,/,/,,2-0-07,5,20398090, 807,3,3,703,9:-,3,,39/,8,25,07:2,8,9479,9,8080:7:,3 78402,9,3907,39:35,/,1,947:8,503/079,7,,9503,9,39:3 474307,/,3,503,9,3,3/,3:,83,31,7479,9,8807,3,3,:93,/03,3 2033,93,:2:702,9,37,7,5,/,:8,/-,,9,:3/,35,/,:8, ,3:9

425,8 %742-402-4820 !07,7/98 30:782,;03970 #03,9,3,7/403 7,/,7/,83:8 -7,8,97:2 ,,,39:3



!&%&!  31,7 4,7/ :9, ,, 307488 24,7/ ,-,9 ,7,3 /,7, 0 4949 ,39:3 ,3 907,3:, 3 -8, /80-,-,3 9742-:8 ,7907 474307 40 7:59:7 5, ,3 /5072:/, 907,/3,401,9471,947805079507903820744/,3507408907402, 31,74,7/,3/80-,-,39742-:8,7907474307/,5,920303,03/4,7/:28,25, 05,7/:2/80-:9

31,7

97,382:7,,2:3

-8,

:,

,3,

20303,

/,07, 

8:-03/4,7/,/80-:931,78:-03/4,7/, ,3489/,731,74,7/:9/,,80-,,-07:9 ,3807/,/,,3,8  - .38244 5,-,907/,5,9/,7/,348990780-:9/,9,82,,/,3480/,7 /,5,9/90,,3 !07,,9,331,74,7/:9 !07,,9,3390381 !02,39,:,3503:9,32:3392-: 073,3,3-0-,3,39:3/03,3 20303,3,3503/079, 203,3,3307802, 203,9:790,3,3/,7,/,3170:038,39:3 02-07,3 #0;,8:,78,8/03,35034-,9,39742-49 %,1,94750393/,,25743488,9: ,!49038907,/3,,792,,3,,9,792,;03970/,3,3,3  -!49038,807,3,3802,0-,: .!49038, 502-:7:,3 ,3:,3 024/3,2 0- ,:-07,39:3 907:9,2, 5,/, :,8 /,07,31,7,/,9,8/,5,9/0;,:,8/03,320,:,3502078,,3:,9  ,39:32439473 502078,,3 00974184404,7/47,2 /03,3 502-0-,3,3 /,3 ,909078,8,39:3

%#!&$% 40/ ,78434,3489 /,3 !034-,9,3 !03,9 ,39:3 0947 ,/, ,:9,8 0/4907,3&3;0789,87,3,$:7,-,,,  499 392,3:030 7,:3,/.:90 4.,7/, 31,7.943,778438 !73.508 41 0/.3090/9435,0  82:/,9 #,39434/:: ,7 ,7/44,:9,8 0/4907,3 &3;0789,8 3/4308,, !7,2434,/ !7,-44!03,9 ,39:3 474307,-&! 2: !03,9 ,39:3 &3,7 #$&/7$409424$:7,-,,, !741/7$,140, 407/:: ,7 2: !03,9 ,,2 / /8 09,,, !0307-9&,,79,,