Laporan Sindrom Down

c

c c
c  c 
c  c c

cc  c  c c ccc ccccc c

c 
c
cc

   c  
c c  c c c   c cc

 
c cccc  cc  c!c c

c  cc c c
 c c c cc  c cc

cccccccccccccccccccccccccccccccccccccccccccccccc c c
  cc

c c"c cc

c

 c 
c c  c ccc  c


c 
c

cccc c

c
c

cccccccc c

ccccc

c
 c

ccccccccc

cccc c

c   c

cccccccc c

ccccc

c
cc cc

ccccccc

ccccc

c c cc

ccccccc

ccccc

c    c cc

ccccccc

ccccc

c
 c!c""""cc cccccccc ccccc # c c""""c c

ccccc

c$ ccc cc cc

ccccc  c

ccccc

c$ c
"c %c

ccccccc c

ccc #c

c&!c cc""""c cc

ccccc  c

ccc

c

c&c

cccccccc c

ccc c

c' c

cccccccc#c

c

c

(   ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc c c

c #$%&'(%'''$c c c

|   "c))!cc c%!)) c

c c

*  c  c +c  c c  !c +!c &c | 

$"c "c  c !c  c " +c "c  c c , - ! c . c $ + c /,.$0)c .+"c c "c !c  1c c c " 2+c "!c "%c  c !c  "c  c "c !c
  "c 3c /

3c # 0)c $! !c"!c"%c  c ""c c+c" c  "c"c  c "c " c "c  c  c   c "! c "! "+c !!+c""""c c)c c c

.!  c c  "c "c  "  "c +c ! !c

!!+c"c)c4 c( c5 c "c+cc!!c c"c

3c # c "c ! c +"c  c " c !%"c %c  c + "c c  )c ,c c  c %c +c !%"c "c " "c "c

3c # c "+c""c c" c!!  c+c) c c c

6c +c  c  "c "!c "%c  c !c   !"c

+c  c " c c ! c  %1c  "c " 1c  c   "c "1 c c !c  - c +c ! !c  c % "c !- c  c !c """"c  c c !"c !c """"c  c %  c" cc  c ") c c c

." 7))c

c c c c c c

c  c c

c

c

$" c c+ccc"!c ccc c%c +c !"c !c  c +" !c c  )c . c c " c +" !c c !c +" !c 8c "+9c 1c  c  c ! "c !!c  c c !c  "!"c c+" !)c c c

2c cc! c  cccc"!c( ! c  !c

"!c c 'c 6c )c ( c "c c +c !c % "c c  cc!c )c c c

 c $ + 1c "  c + c  c c +c  "c  c !c  c

! c #c + )c .c  1c "  c + c  c c  c | "c .+ "!c+c "c!c c! c ###c+ )c6 c  c"c"  c+ c  cc c$ + c c  c!  c c| "c.+ "!) c cccccccccc. cc  c! "c c !cccc"c+c!c !c "c  c ""c " c 1" ! 1  c " c +c )c: c !c""""c+c+ c cc c !c"c " c +c + c c   "c "c  c +c " c c c !c!c"c " )c c c c c c c cccccccccccccccccccccccccccccccccccccccccccccccccccccccccc cccc c c c c

c

c

c  c c c )   c

c . c c  c "  c " c +c  "c  c     c " c +c  c  " ! c c  +c  "c "c " c c ! "! c +c"cc )c3 c c  c c! !c"c +c !!c  c ! c  c  c  c c  c  c c !!c  c! "c+c!"c !  !c)c 3c  c c +c  c "c !% c  c  "c  c !c "c c  !c+"c c"c c+c% "c% c"+c +"c)c(+ c+c c+c+ cc"c c  !c% "c % c"+c+"c)c c c c c c c c c c c ccc c c c

ccccccccccccccccccccccc

c c

c

c
*
*c  c c c )'+,-(c#$#,.+cc 3"""c  c c + c  c "c c  c c "c c  c +c  )c
!c "c  c  "c  c c !"c  c +c ! "c  "c c c  c +"c "+c!  c )c " c;c c"c cc  c  "c  c  ) c *!c c % c  c c +c  "c  c "!c! "c  !c*  c 1c$  cc* " c&! ) c c <"!c "!c %c !!c +c "c "c  c )c  " c !!c %c ""c  c c c  "c " c  c c c c "c  "c!"c!"c"c cc c  c!  ) c c c

c

c c c c c c c c c

c c

c

c ) c  c

c 0c =c c +c c c !c "c !c + c   "c +c  c !  c !"c   "c "c +c   c  c )c <"!c  c  "c  c " !c   "c c !c+c "c c cc! "c" c"c2c" !c   )c 0c  c  c c %""c   "c !c "c  c  c  "!c!cc c) c c c

&=.=3:c.=2&:$c:>2c , c ccccccccccccccccccccccccccccccccccccccccccccccccc
 c " c+ cc c c #c!cccccccccccccccccccccccccccccccccccccccccccccccc c c ## c c!cccccccccccccccccccc cccccccccccccccccccccccccccc c c ##c

#c!cccccccccccccccccccccccccccccccccccccccccccccccc c c ### c

c!cccccccccccccccccccccccccccccccccccccccccccccccc c ccc  c #c!cccccccccccccccccccccccccccccccccccccccccccccccc c cccc# c c!cccccccccccccccccccccccccccccccccccccccccccccccc c cccc #c c c c "c =c +c !c "c "c   c / c ?0c "+c  c !!c "%c %c + c   "c +c !  c !c "c  c) c c
 c c %c !c c "c "c  c ) c c

c

c c

c

c  c  c c c   cc c

*  c c "c "c c"c" c  )c "c

" c  1c ! c / c c !c ! 0c   "c c !c  c"c )" c  c! c "c !c+c+ cc ")c| ccc!c c c+c"c  c "  c + c c "c  !c  c ! c "c  c "c+c c  !c) c c

*  c  c  c "c +c !c "c " c  c c

 !c +"c ;c c ;c  +c  "c  c " c c !c cc;c "c c"!cc!c )c c

/. c %"c c c   c  c  !c "c  c +c  "c

!0c c c c c c c c c c c

c c

 * c *  c c +c "c c" cc"c c cc !%%)c >  1c  c !c  c  c c  c   c c!c c c!  c c"c c " c c cc % c $  )c    c  c   c c c + c  c "c +c c  !c /c "0c c  c  c   c + c  c +c ! "c c /c "0)c .  c +c c c +c ! "c !c  !c c c "c c  c !%  +c  )cc c

6 c  c  c  "c  c c "/ %! 0c c  c

 c  c c  c  c c "c  c  c cc !  c  c !c  c  c c    / %! 0c c !c  c c  c " c "c !c "c  ) c  c c  c  !"c;c c"c+c ") c c

c    c c . cc% c8* " c &! 9c"c% c+c c"c +c "c"c  c)c=+c+c  !"c;c c"c  c c +c  "). c c % c  c  c  !"c  c c !c )c* " c! c "c c c"c c!c c c+c"!  c c! "!c"cc"c+c  c c  +c c "c )c
c " +c c  c c  c "c  1c

c c " c  c c "" c "c !"c   "c c  c"c+c+ c cc!  " cc c c)cccccccccc c c c c

c c

c

"c *  *  c  c c '(.c/#%.c0.1.+'2c c  )c  c
3c   c c c *!c c  c +c % c  !c """"c  c c %c """"c  c )
 c +c  c "!c  c "" ""c  cc+ c"c+cc c" c")c3+!c  c "c c "c """"c  c c  c ""c ! c c )c "c"c"c+c cccc 1c "c """"c  c c   c   ) c
" c  c """"c  cc%c+ c cc"" ""c c  !cc""c !c )cc 3"""c  c c %c + c %"c +c %c  !c ! c "  c c ")c .  c !c !c "c %c + c " !c +c   c  c !c )c$!c"c%c" !c!) c cc. c  !c """"c  c c %c  c  c " c  c """"c ).  c !c%1"c+ c c c+c  c)c     c  !c c c  c !c +"c "" ""c  c c   c % "c )c
!c  c"" ""c cc c c !c c! "c!!c c""""c )c  c  c !1c! c """"c  cc c  cc )3 c "c %c  c " c c "c c  c  c c  c "c  ").  c !1c c"" ""c cc%c  c"c c )c /c c %"c c c  c  c  c  c  !c     c  c c +ccccc  !"c"1" cc  c0c c c c c

 )c  cc c c .  c  c "1c " c c 1c "" ""c  c c %c + c  c +c "!c c !c c c c "" ""c  )c   c +c  c % c c % c "" ""c  c c  c "c + c % % c +c "c c % c " " c +c ""c "c  )c .  c !1c !"c !c """"c  c c +c + c !c  c )c   c  c  "c  c 8  c 9)c   c  c !c ! c  c !"c c c """"c !c   c  c c !c ! ")c  c  c !1c !"c !c "c %c  c  c c  c """"c  )c /c . c %"c c c  c  c  c  c  !c     c  c c  c!cc c0 c

 )c  c  c 3"""c  c c %c + c  c  !c c "" c c """"c  c +c  )c 3"""c  c c + c "" c +c "c "c  c "" ""c  )c .  c !1c """"c  c c %c + c % c "" c +c "c c %"c c % c "" c c % c "" c "c "c %c ! ) c  c !c !"c "" c "c  c  c "c )/. c %"ccc c c  c c !c     c  cc c c"" 0 c

 )c  cc 3+""c""""c cc+ c!"c+c c!c  ")c 6 c  c ! c +"c "" ""c  c c c !c "c  c """"c  c +c  )c .  c !1c "" ""c  cc%c  c c  !c c"c!c"cc + c  c +c )c 3c  c +"c "c "c !!cc"c"c ""c"c! c"" ""c c+c  )c c c c

cc    c  c c c    c c  c c 

c
!c """"c  c c  c ! "c  !c "!c % "c  "c   "cc"" ""c )c. c " c"c  +c  cc c c c""""c cc!!!!c"c" !c  ")c6 c  c +"c "c "c "! c +c  "c  c !! !!c "c +c ! "c"!c! c""""c c+c  c+c"! cc "!c  ) c

 c c c
!c ! c """"c  c c "c !c  c ""  ""c  )c 3+c !"c  " "c !!c +"c "c ! " c !c  c !c ! c c !c c "" ""c  )c
!c ! c "c %c "c "!  c %c "c  "c  c "" ""c c+c+cc")c6 c  c c "c c""c   c!"c+c   c c") c

 c c  c
!c  c "c%c  !c"!c% " c  "cc""  ""c )c$"c"c !c!"c !" cc  c"c" c "c! c% 1c"c+1cc)c6 c  c "c c"c! "c  c !"c + "c   c c " !c "c !!+c +c "c  c " c ")c 3"""c  c c %c + c  c ! c """"c  )c $"c "!1c  1c +"c !c ! c """"c c+c  cc +c" c +c! "c! c""  ""c  )c 3"""c  c c %c "c + c c   c   "cc"" ""c c+c+c+)c

cccccccccccccccccccccccccccccccccccccccccccc #c

c c

 c c  c)   c  c  c "c " c "" ""c  c 1c "+c "c "!1c% 1c  1cc ! c! "ccc""""c )c 3"""c  )c 3"""c  c c "!c  c +c "c!c!! c""""c cc!"cc ""+c"c!!  !!c "c "c 1c  !c %cc c "+c "c % c 1c   cc !)$"c! "cc ""c ""cc !c"c  cc!!!!c"cc"" c cc%!c") c c

 c c  c   )c 3"""c  c c  c "c + c " c "c 1c "1c  " c 1" 1c !"c "c c !)c 6 c  c  "c  c "c " ! c "c ! "c !c "" ""c  1c !c " c"c  cc  "cc"" ""c )c c

 c c c 3"""c  c c ! "c +c  c c !c  c c"c"! "cc!c)c$"c"c+ cc  c  cc"" ""c )c $"c"c % !cc  c !c c  c c  " +"c  c  c % "c "c "c ! "c  !! )c
c c !c  c "c  c %! c %c "c c "" ""c  1c "c"c c cc  " cc1c% cc c "c  c%! c"c"c") c c c c c c c c

 c c  c  c
"c   c """"c  c c  c !c c   "c c""""c )c $"c! "c!c "cc!c  " c c ).  c !c "c %c  c c  c  " c c c  c c "c c  c !)c
 c "c c "c +c%c! "c ""c "!c1c"c! "c!c "!c c"! ""c   c" cc "c! c"" ""c )c

c  c c   c 3"""c  c c   +c + c  ! c !-!1c "c "c "! c  c  )c (+"c +  1c "c  ""c "! - ! c " )c $"c ! "c c "c c c c !!+c +c  c "c " )c $"c %c "c  %" c  c " c  "c "c "c  c)c$"c%c"c+"c  c  1c !c c c""c% c )c >  1!!c %c "" ""c  c c +c  !c "!-!cc%c -!) c$"c+c+ c ! c  c +c   c c "!c" !c!!+c c1c" 1c%  % cc +"!c " )c .c +c c  c " c "c "c  c ! - c "c """"c  c +c  c "+" c  c  c " "c c+"!)c c c c c c ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc c

c c

 cc c  c c cccccccccc

 c
c c 3"""c" c"c cc  c  c c" !c !!+c  c +c " !c c c  c ! c %!c c )c $ c %!c +c   c  c %!c  )c $ c %!c  c  c c  c % c  !c @!  c .!c  !c /@.0c  !c c c+c" c c!c%!c"  cc")c c c .  c !1c % c %!c  c +c  c  c |!  c .! c  !c /c |.0c  c c c  c !c ! c "  c c ")c $ c %! c  c "c +"c c ! "c !c  c  "!c +c "c c  c  c "  c !c " c  c  c "c %!)c = c  c "c +c " !c"c%!c""c""c!!)c cc .  c !1c  c +c  c  c " !c %! c  c  c !  c "" c /c
!!c !c |!  c Ac
|0c c %c  c %!c  c " c /c +! c  0c  !c !!c +"c ""c B""c  c c !c "c !"c  )c $ c  c  c  !c    c !c ! c )c c cccccccc ccc c c c c ccccccccccccccccccccccccccccccccccccccccccc c c c

c c c

 c

c c $ cc +c   c  cc""c c ""c cc +cc c"c c + c  )c  c !+c  c  c  c +c ! "c !"c /! 01 +c "cc c cc c cc+ c  c cc + c"c!"c c c +c!c "c c"!c!c%!c"c "c! "c!c""c! c+!c c!ccc  )c. c c " c c +c ! "c !"c + !c +c  "c Cc 6 c  Dc "c  c  "c  !c  c +c ! "c  c  c  c "!)c 3 +1c + c "c   c  c  c c  c "c !c !+c  c "  c  c c !+c "c  !c c c !"c c c)c.  c !1c"" ""c  c"" c c c ! c c) c c c c c c

  c c c

c c$ c 6 !   c %c  c  "c !c "" ""c  c c

 !c c ""c B""c ""c c ! )c 3" c c  "c  c #;c  c ""c B""c  c )c 6 c  c +"c "! "! c  c ! ! c " c  c c +c  c +"c  "+c +" !c c /|*'|2*:| =|'c =2.*|(='=*E0))c . c "c %c + c   "c"c cc! c  !c " ) c c

c c c c cccccccccccccccccccccccccccccccccccccccc c c c

 c  c  c ccccccc .! c """"c  c c + c "c +c !c  ): c !1c  c c +"c "" ""c !c ")c !c c  c   c")c*!c c"c %)c.c" +1""  ""c  c c   c "!c  " c c " !c ")c ( c """"c  c "c + c !c c "c ! "! c /c =F0c +c ! "c    c #)c = c +"c "c ! "c !c  " c c  c  ")c
c  "!c  c 1c "c   c  c "  !c  c c "c "c  !c !c "1% c c !c  c "c !c  c c ")c !+c "c  c !c  c   c  c """"c  )c .  c !1c "+c !c  c "c ! c  c 1 " c c c    c %c !c !c ")c 2c "c!c cc "c"c "c  "!c!ccc " !c")c c c
"c " ! c  1c ""c B""c  c c "c + c " c

 c

"c

c

1 "c

1 " c

1 "1!"c "c !c !)c = c  "c "c "c ! "c c c """"c  )c 2c "c   c "c !c  ""c "c """"c % c  c !c  )c 6 c  1c % "c"c!c  c c c" c") c c c c c cccccccccccccccccccccccccccccccccccccccccccccccccc c c c c c c c c

c c  c c c

. c "  c  c  c c !c !"c !c  c )c 2c  c c c ! c !"c "" ""c !c c +c + c  c c  c "c  c "c c   c 1" ! 1c  )c |!c !+c

 c! c"cc!  c!)cc c  cc
c c

$!c $c  c ! c "c  " c ! c c !c  !c "1  "c !c !)c 3!  ! c "c !!c !c   "c  c !c c "c "" ""c  c )c $!c  c cc"c c! c!c!c"" ""c  c  c  " c 1c !"c !!1c !"c " !c c %c c !c c !c )c $   c "! - ! c  c "c  1c ""  ""c  c c !c c "  c c "+" c "c "c !c +!c c c c )"c c !!)c c .  c !1c c !c  ! c """"c  c ! c    c "c !"c c "c  c    c +c !  c  c """"c  c c ! c c c % ! c +c "c !c + "c   c c ")c *c  1c "c !cc"c" !cc+"!ccc c"c c"c)c6 c  1c "!"c"c  c"" ""c  )c* c  c %c  c  "c !%c c  c   c "c c "c c c "c "c  c   c "c !!c +c "c !c !c ! "c!)c ccccccccccccccccccccccccccccccccc /c !!GAA) )A!! A ## #A! " #0c c c c c c c c c

 cc  c c

* c  c  c !"c ""c B""c c  c c  c "c " c c !c  c c !c "+)c .  c !c !! !!c %c c !"c !c  ")c6 c  c"c"c c c c  cccc!c ! "c   c ! c " c  !c "c +c "c ")c $   c "! - ! c  1c """"c c  c c !c ""c  !c " ! c "c  c c  c  c "c  c "c c !cc!c !c c c!c)c: c !1c"c!c   "c"ccc !c c c"c! )c| c!c  c "!c "c """"c  c c )c $"1c "c  c !c !c "c  c  c  )c .  c !)"! - ! c  1c  c " c  c"c%1 cc"c!cc" !c )c c c c c  cc*c c c

* c  c  c % c  c !"c  " c c " ! c  c )c * c  c!!c"c " c" c% "c"! - ! cc" c  1%c  cc"  c c!!c"%cc )c* c  c !"c   c " ! c c  c "" ""c  c c c " c % "c!c c! c% 1c 1c" c%cc !c"%c )c * c c "%c "c c "c  c c "c  c  ""c !c  )  +c ! c  c  c %c  c " c  c !c  %c " c )c c c

c c cccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc c c c c c c c

 cc

 c c

* c!cc  c!c "!"c""!c!!1c "!"c!"c!!cc  c"" cc!c c c!   c!")c.  c !1c "!c"! - ! c  c !c  c c " 1c "c c "  )c 6 c  c  !c  c !c )c * c  c  c  ""c  c c c "c !c +c "c !c !"c "c ! !c  +c ! c 1 c c  +c )=c c  c  % c !c c  c "c !)c
"c  c  !c %c c c +c ! c  c !c """"c" c c) c c c c c c c c c c c c c c c c c c c c cccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc c c c c c c c

›


c

c c

c c


 c c

c

c

c


 c c

c c

c c


 c c

c

c

c

c

c


 c c

c c c c

c c

c

c

c

  ) c c 

c

|!1c$)'1c 1)Hc&!1c|)I)c/##0) V
  
 

c c
     V
  
  )c,  c2 1)c (!1c')1c$F1c$)()1c$ 13)1c( "1c)1Hc* 1c&)Ic/##0)c   c  
     V
  
  G| 5 c !)c2!c5! 1 )   c c c

!!AA" ) !)A# #A# A "  """"")! c !!AA !! c) !)A# #A#A! c  ! )! c !!AA"c ) !)A##A# A!c B"!"  c)! c !!AA")"c!"cc !))+ c !!AA""" ) !)A##c

A! "%)! c

!!GAA)   !)-)+A+" !A3" ""A. ) c !!AA)  )AcA"  !!!c+c !!GAA)  !)AJ+A)!K " c !!GAA)))+AA !A! " J" !A J) c ) "  )A " A. J c  ") )!A)))A  !#)!c ) )AA  A.  
!c c c

c c c

ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc c c