Mekanisme Pertahanan Tubuh Tubuh Kelompok 7 Rismauzy Marwan Imas Ajeung P Andreas P Girsang
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Imunitas atau kekebalan adalah sistem mekanisme pada organisme yang melindungi tubuh terhadap pengaruh biologis luar dengan mengidenti!kasi dan membunuh patogen serta sel tumor" #istem ini mendeteksi berbagai ma$am pengaruh biologis luar yang luas% organisme akan melindungi tubuh dari in&eksi% bakteri% 'irus sampai $a$ing parasit% serta menghan$urkan zat(zat asing lain dan memusnahkan mereka dari sel organisme yang sehat dan jaringan
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Tubuh Tubuh manusia manusia mempunyai mempunyai banyak sekali sekali mekanisme mekanisme pertahanan yang terdiri dari berbagai ma$am sistem imun yaitu organ lim&oid *thymus% lien% sumsum tulang+ beserta sistem lim&atiknya" ,antung% hati% ginjal% dan paru(paru juga termasuk dalam mekanisme pertahanan tubuh" #istem lim&atik baru akan dikatakan mengalami gangguan jika mun$ul tonjolan yang membesar dibandingkan keadaan biasanya" -al ini dikarenakan kelenjar lim&e sedang berpasangan melawan kuman yang masuk dalam tubuh"
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Sistem Sistem Kekebalan Tubuh Pada Manusia Mekanisme Imunitas terhadap Antigen yang /erbahaya /eberapa mekanisme pertahanan tubuh dalam mengatasi agen yang berbahaya di lingkungannya yaitu0 1+ Pertahanan !sik dan kimiawi0 kimiawi0 kulit% kulit% sekresi sekresi asam lemak dan asam laktat melalui kelenjar keringat dan sebasea *kelenjar berbentuk kantong ke$il yang terletak di dermis+% sekresi lendir% pergerakan pergerakan silia% sekresi air mata% air liur% urin% asam lambung serta lisozim dalam air mata" 2+ #imbiosis dengan bakteri 3ora normal yang memproduksi memproduksi •
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Respon Imune Innate Respon ini merupakan mekanisme me kanisme pertahanan tubuh non(spesi!k yang men$egah masuk dan menyebarnya mikroorganisme dalam tubuh serta men$egah terjadinya kerusakan jaringan" Ada Ada beberapa komponen innate immunity% yaitu 0 a+ Pemusnahan emusnahan bakteri intraselular intraselular oleh sel poli(mor&onuklear poli(mor&onuklear *PM6+ dan makro&ag" b+ Akti'asi komplemen komplemen melalui jalur alternati&" alternati&" $+ )egranulasi )egranulasi sel mast yang yang melepaskan melepaskan mediator mediator in3amasi" in3amasi" d+ Protein Protein &ase akut0 akut0 (rea$ti'e protein protein *RP+ yang mengikat mengikat mikroorganisme% selanjutnya terjadi akti'asi komplemen melalui jalur klasik yang menyebabkan lisis mikroorganisme" e+ Produksi Produksi inter&eron inter&eron al&a *I86(9+ oleh oleh leukosit dan inter&eron inter&eron beta beta •
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Respon Imunitas #pesi!k /ila mikroorganisme dapat melewati pertahanan nonspesi!k;innate immunity% maka tubuh akan membentuk mekanisme pertahanan yang lebih kompleks dan spesi!k" Mekanisme imunitas ini memerlukan pengenalan terhadap antigen lebih dulu" Mekanisme imunitas spesi!k ini terdiri dari imunitas humoral% yaitu produksi antibodi spesi!k oleh sel lim&osit / *T dependent dan non T dependent+ dan mekanisme ell
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Mekanisme Respon Tubuh terhadap Serangan Mikroba •
Respons tubuh terhadap serangan mikroba dapat terjadi dalam beberapa jenjang tahapan" Tahapan pertama bersi&at
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Imunolog Imunologii Toleransi oleransi Terhadap erhadap Antigen Bakteri •
Toleransi Toleransi adalah properti dari host dimana ada pengurangan imunologis spesi!k dalam respon imun terhadap antigen tertentu" Toleransi ke
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Mekanisme Respon Tubuh terhadap Serangan Bakteri •
/akteri adalah kelompok organisme yang tidak memiliki membran inti" /eberapa kelompok bakteri dikenal sebagai agen penyebab in&eksi dan penyakit" /akteri dapat ditemukan ditemukan di hampir semua tempat seperti di tanah% air% udara% dalam
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Respons Imun Terhadap Bakteri Ekstraselular •
/akteri ekstraselular dapat menimbulkan penyakit melalui
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Imunitas Alamiah terhadap /akteri ?kstraselular •
Respon imun alamiah ala miah terhadap bakteri ekstraselular terutama melalui mekanisme &agositosis oleh neutro!l% monosit serta makro&ag
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Imunitas #pesi!k terhadap /akteri
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Respons Imun terhadap Bakteri
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Imunitas Alamiah terhadap /akteri
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