Heparin Injection

TRADE NAME : Heparin leo , heparin sodium GENERIC NAME : Heparin

ONSET

20 ± 60 min.

Immediate

CLASSIFICATION: Anticoagulant

PEAK

1 ± 2 hrs

1- 2 h

DURATION

8-12 hrs

INDICATIONS

y

y y

CONTRAINDICATION

y

y y y y

COMMON ROUTES & DOSAGES  NURSING CONSIDERATION/ INTERVENTIONS

IV

Prophylaxis for DVT and PE, tx of arterial embolism, pulmonary embolism, venous thrombosis Prevention of clotting during arterial/heart surgery Anticoagulant for use in blood transfusion and dialysis

Hypersensitivity Severe thrombocytopenia Any uncontrolled bleeding Clinical consideration: consideration: Not intended for IM use. use. CV ± hemorrhage CNS: Fever ,chills, headache GU: Hematurea Anaphylaxis Local irritation at SC site Adult SC 10,000 ± 20,000 unit followed by 8000 ± 10, 000 unit tid IV 10,000 unit followed by 500 ± 10,000 unit 4-6 times /day Usual infusion infusion dose 20,000 ± 40,000 unit/day ASSESS: hx of hypersensitivity, elderly may require decrased dose NDX: Tissue perfusion, ineffective. Trauma, risk for. PLAN/IMPLEMENT: - Administer: By deep SC injection, intermittent IV injection, continuous IV infusion. - Avoid IM (danger of hematoma formation) - Can be mixed with dextrose, dextrose/NaCl, normal saline, invert sugar  - Prepare fresh solutions; avoid storage for >24h - SC: use lower abdomen; change needle after preparation; don¶t aspirate; rotate sites; avoid massaging. - IV : use infusion pump; avoid mixing with other drugs in solution; have protamine sulphate available for OD Monitor: Hepatic, CV, and renal status; signs of hemorrhage in abdominal and 30 m of heparin lumber pain - Treat with protamine sulphate (w/in 30m administration) Patient Education: - report any bleeding/bruising immediately - Avoid smoking and alcohol - Use electric razor/depilatory for hair remobal - Avoid aspirin containing products - Check with physician/pharmacist before taking OTC preparations - Women: avoid breast feeding. Evaluate: Improved blood flow y y

SIDE EFFECTS

SC

y y y

y

y

y