CHOCOLATE BASED CALCIUM LOZENGES Category: Lozenges
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Solid dosage forms intended to slowly dissolve in the mouth
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Deliver drugs systemically by releasing the drug either bucally or sublingually for absorption
Synonym: Calx Chocolate Lausiae Description of Final Product:
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the lozenges are chocolate-brown in color with a smooth surface.
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The lozenges are round disks with a diameter of 2.5cm, and each appears uniform in size with a depth of 0.5cm
Use/s of calcium in general:
Calcium – as a reducing agent in order to extract metals such as uranium, zirconium and thorium
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Required for the growth and deve lopment of the bones
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Responsible for the rigidity of bones
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Treating and preventing rickets and
Anaesthetics
Demulcent
antibacterial
Kinds of Lozenges:
from syrups of sucrose & other 1. Hard Lozenges – from sugars and/or carbohydrates that are boiled so that the moisture content in the product is 0.51.5%. preparation is similar to candy making
2. Soft Lozenges – from flacored fatty base such as chocolate, PEG base & sugar-acacia base glycerinated gelatin-base 3. Chewable Lozenges – glycerinated chewable oral drug preparation which was made after a candy “gummy worms” or gummy bears” for children was launched
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Method of Preparation 1. Hand Rolling Does not require special calculation and equipment
osteoporosis
Cheese – made using calcium ions to promote the coagulation of milk
important when Cement and mortar – important constructing buildings and other things, are made using calcium
Calcium hydroxide – to determine whether carbon dioxide is present; commonly used in science laboratories
Calcium Tungstate – in bright paints, x-ray studies and fluorescent lights
Calcium Carbonate – to make lime and limestone which are important in the glass industry
Calcium Gluconate – food additive which is also added to vitamin pills
Calcium Sulfate – blackboard chalk
Calcium Hypochlorite – to disinfect pools, bleach, deodorants and fungicide
Calcium Carbonate – antacid to relieve heartburn
Use of Lozenges:
Cepacol – sore sore throat
Nicorette – smoking smoking cessation
Fentanyl – cancer cancer
2. Fusion or Moulding Method used for hard candy, chocolate, gummy gel chewable Require heat, special mould, skills and calculations Dose unit may be determined either by weight or volume or both
Advantages
Disadvantages
Do not require Special calculation Special equipment but a pill roller is useful can be made only by using heat and moulding – hard candy, chocolate, gummy gel, chewable lozenges finished professional appearance when wet made
Preparing and forming requires experience and good techniques
Special moulds are require Hanling some types of base materials requires special skills and experience Caution must be used
