Six Weeks Anti-aging program

Your Six-Week Anti-Aging Plan

Rosenberg, M.D. MEET THE AUTHOR: Mark Rosenberg,

Table Of Contents PAGE

Mark Rosenberg, M.D. is director and founder of the “Institute for Anti-Aging” in in South Florida. For the past 15 years he has combined modern medicine with nutrition, exercise and physiology to create a natural program for healthier living. Dr. Mark Rosenberg received his undergraduate degree from the University of Pennsylvania and graduated from Georgetown University School of Medicine. He then completed his residency in emergency medicine in San Antonio, TX at Brooke Army Medical Center, where he won the award of “Teacher and Resident of the Year.” In 1997, Dr. Rosenberg became a diplomat of the American College of Anti-aging Medicine. He has since become a highly sought-after speaker and lectures frequently on topics such as integrative cancer therapy and anti-aging medicine. In 2009, Dr. Rosenberg will be regularly lecturing in Asia, Europe, and the Middle East. Dr. Rosenberg has published a physician’s guide to the treatment of drug toxicities and served as a consultant to several hospitals for the treatment of drug overdoses. In addition to drug research, Dr. Rosenberg is avidly involved in supplement research, and has served as the Chief Science Officer for several supplement companies including VitalMax Vitamins. Dr. Rosenberg has spent much of his time over the past few years studying cancer. He has developed a novel protocol that integrates standard chemotherapeutic regimens with non-toxic natural supplemental regimens. Dr Rosenberg was featured on on Fox News for inducing remission on a patient with cancer that had spread from the lungs, to the liver and spine. Wake Forest University is now currently beginning a study using this protocol.

............................................................. ........................................... ........... HOW AND WHY YOU AGE ............................. The Most Important Medical Discovery Of All Time ....................... .............................................................. ........................................................... ........................... The Cycle of A Cell .............................. Keep Your Homocysteine Level In A Healthy Range.......................

1 1 2 3

RESETTING YOUR BIOLOGICAL CLOCK .............................. ......................................... ........... 5 Eternal Youth .............................. .............................................................. ................................................................ ..................................... ..... 5 Slow The Aging Process ............................... ............................................................... ................................................ ................ 6 ................................................................ .......................................... .......... YOUR YOUTHFUL MIND ................................ .............................................................. ................................................ ................ The Physiology of Stress .............................. .............................................................. ..................................... ..... Attaining Your Mental Clarity Clarity ..............................

8 8 9

........................................................... ........................................................... ........................... 11 MUSCLE IS YOUTH........................... The Closest Thing To An Anti-Aging Pill .............................. .............................................. ................ 12 Forget Wear and Tear Exercise ............................ ............................................................ ..................................... ..... 13

THE ANTI�STRESS HORMONE .............................. .............................................................. ................................ 14 .............................................................. ................................................................ ................................ 15 Declining DHEA.............................. .............................................................. ..................................................... ..................... 15 The Benefits of DHEA .............................. RESTORING MASCULINITY WITH HORMONES ........................... 17 ............................................................ ................................ 18 Restoring Testosterone Naturally ............................ REAL HORMONE REPLACEMENT IN WOMEN .............................. 20 Natural Hormone Replacement ............................... ............................................................... ................................ 21 Herbal Relief for Menopause................................ ................................................................ ..................................... ..... 22 .............................................................. ..................................... ..... 23 REVERSING HUMAN AGING.............................. ................................................... ..................... 23 Why We Call It the Fountain of Youth Youth .............................. .............................................................. .......................................................... .......................... 25 Restore Your Youth ..............................

YOUR 6 WEEK ANTI�AGING P LAN ............................ ...................................................... .......................... Week 1: Take Anti-Aging Vitamins ............................... .................................................... ..................... Week 2: Apply Stress-Reducing Stress-Reducing Techniques............................. .................................. ..... Week 3: Begin Anti-Aging Exercise Routine.............................. ................................... ..... ................................................. ..................... Week 4: Begin To Change Your Diet ............................ ............................................... ................ Week 5: Balance Your Sex Hormones Hormones ............................... Week 6: Regain Youthful Levels of of HGH..........................................

26 26 27 27 28 29 30

Published by: Almark Publishing PO BOX 17108, Bridgep Bridgeport, ort, C 06673 All right reserved. No part of this book may be republished in any form without the permission of Almark Publishing. © Copyright 2008 Warning-Disclaimer: Almark Publishing has written this book to provide Warning-Disclaimer: information in regard to the subject matter covered. It is offered with the understanding that the publisher and the a uthor are not liable for the misconception or misuse of the information provided. Every effort has been made to make this book as complete and accurate as possible. Te purpose of this book i s to educate. Te author and Almark Products Inc. shall have neither liability nor responsibility to any person or entity with respect to any loss, damage, or injury caused or alleged to be caused directly or indirectly by the information contained in this book. Te information presented herein is in no way intended as a substitute for medical counseling. Pregnant Pregnant or nursing women especially should consult their physician for proper nutritional guidelines. Like What You’ve Read Here? … Pass It On!

To Readers, Health and Nutrition Publishers, Editors, Bloggers, Marketers, To and Webmasters: You may pass this report on without charge, as long as you keep this report You report exactly as written and formatted, with no changes, including full attribution to VitalMaxVitamins.com,, as well as corresponding copyrights, and hyperlinks. VitalMaxVitamins.com


•

www.VitalMaxVitamins.com

Published by: Almark Publishing PO BOX 17108, Bridgep Bridgeport, ort, C 06673 All right reserved. No part of this book may be republished in any form without the permission of Almark Publishing. © Copyright 2008 Warning-Disclaimer: Almark Publishing has written this book to provide Warning-Disclaimer: information in regard to the subject matter covered. It is offered with the understanding that the publisher and the a uthor are not liable for the misconception or misuse of the information provided. Every effort has been made to make this book as complete and accurate as possible. Te purpose of this book i s to educate. Te author and Almark Products Inc. shall have neither liability nor responsibility to any person or entity with respect to any loss, damage, or injury caused or alleged to be caused directly or indirectly by the information contained in this book. Te information presented herein is in no way intended as a substitute for medical counseling. Pregnant Pregnant or nursing women especially should consult their physician for proper nutritional guidelines. Like What You’ve Read Here? … Pass It On!

To Readers, Health and Nutrition Publishers, Editors, Bloggers, Marketers, To and Webmasters: You may pass this report on without charge, as long as you keep this report You report exactly as written and formatted, with no changes, including full attribution to VitalMaxVitamins.com,, as well as corresponding copyrights, and hyperlinks. VitalMaxVitamins.com


How And Why You Age Anti-agi Anti -aging ng is the newes newestt and and fastest fastest grow growing ing branc branch h of medicine. When I lecture on Anti-aging, I have learned from the audience to clarify one thing first. Anti-aging is not the same thing as life extension. That would make it anti-death. But aging and death are two different things. Aging is the Aging the proce process ss by whic which h you you gradua gradually lly weak weaken en and and lose function. Anti-aging seeks to understand this process and inter vene to preser preserve ve youthf youthful ul chara character cteristic istics. s. The The recent recently ly discovered genetic control of aging has opened up a whole new world worl d of poss possibil ibilitie ities. s.

The Most Important Medical Discovery Of All Time History may mark the beginning of the 21st century as the time when we finall finallyy unloc unlocked ked the secre secrets ts of agin aging... g... and and learne learned d how how to stop the process. It will change the course of human history. Yourr body You body is con constan stantly tly renewi renewing, ng, rebui rebuildin lding, g, and and repairi repairing ng itself itself throughout your life. With all this constant renewal, you should stay young you ng foreve forever. r. But But you you don’t. don’t. We all all age. age. Even Even newly newly mint minted ed cells cells from an 80-year old are readily recognizable as cells from an aging body. These brand-new cells look and act older than than cells from a younger you nger pers person. on. How How can can this this be? be? In 1990, Natu published a groundbreaking article based Nature re published on something called the telomere . It changed forever our understanding of the aging process. Previous theories of aging, such as free radical damage, glycosylation, collagen cross-linking or other proposed mechanisms, now

1


•


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appear to be simply features of the aging process but not the true cause . To say that we age because of free radical damage is analogous to the FAA announcing that the cause of a plane crash was gravity. Clearly, the force of gravity pulled the plane to the ground. But gravity exerts equal force on every plane in the sky, most of which safely reach their destination. In the same way, our bodies are assaulted by free radicals from the day we are born. We have mechanisms that effectively quench free radicals and correct the damage. We must understand why they stop. The story begins with Leonard Hayflick’s accidental discovery that cells divide about 80 times and then slow down and stop. This is now known as the “Hayflick Limit.” We now now know know why our our cells cells stop divi dividing ding.. It turns turns out that there is a mechanism built into each cell, a sort of clock that limits the number of times a cell can divide. It is controlled by something called a telomere, which is a stretch of DNA that occurs at the end of every chromosome.i

The Cycle of A Cell Most of the cells in your body have the ability to reproduce at will. But, contrary to a century of scientific doctrine, we now know that each daughter cell does not receive a complete copy copy of the parent cell’s DNA. Each time a cell divides, a tiny portion of the DNA, a portion of the telomere at the end of the chromosome is lost. Each new generation of cells have slightly shorter telomeres than their parents. In fact, you can judge the age of a cell by measuring


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2

How And Why You Age Anti-agi Anti -aging ng is the newes newestt and and fastest fastest grow growing ing branc branch h of medicine. When I lecture on Anti-aging, I have learned from the audience to clarify one thing first. Anti-aging is not the same thing as life extension. That would make it anti-death. But aging and death are two different things. Aging is the Aging the proce process ss by whic which h you you gradua gradually lly weak weaken en and and lose function. Anti-aging seeks to understand this process and inter vene to preser preserve ve youthf youthful ul chara character cteristic istics. s. The The recent recently ly discovered genetic control of aging has opened up a whole new world worl d of poss possibil ibilitie ities. s.

The Most Important Medical Discovery Of All Time History may mark the beginning of the 21st century as the time when we finall finallyy unloc unlocked ked the secre secrets ts of agin aging... g... and and learne learned d how how to stop the process. It will change the course of human history. Yourr body You body is con constan stantly tly renewi renewing, ng, rebui rebuildin lding, g, and and repairi repairing ng itself itself throughout your life. With all this constant renewal, you should stay young you ng foreve forever. r. But But you you don’t. don’t. We all all age. age. Even Even newly newly mint minted ed cells cells from an 80-year old are readily recognizable as cells from an aging body. These brand-new cells look and act older than than cells from a younger you nger pers person. on. How How can can this this be? be? In 1990, Natu published a groundbreaking article based Nature re published on something called the telomere . It changed forever our understanding of the aging process. Previous theories of aging, such as free radical damage, glycosylation, collagen cross-linking or other proposed mechanisms, now

1


•


telomeric length. When the telomere gets sufficiently short, the cell enters programmed cell death. So the telomere serves as a counter, or clock, for the cell. But the telomere does more than just tell time. As the telomere shortens, it changes the behavior of the cell. Cells with shorter telomeres begin to slow down. The signals that control hormone output and immune function become weaker. They start to act old. ii

appear to be simply features of the aging process but not the true cause . To say that we age because of free radical damage is analogous to the FAA announcing that the cause of a plane crash was gravity. Clearly, the force of gravity pulled the plane to the ground. But gravity exerts equal force on every plane in the sky, most of which safely reach their destination. In the same way, our bodies are assaulted by free radicals from the day we are born. We have mechanisms that effectively quench free radicals and correct the damage. We must understand why they stop. The story begins with Leonard Hayflick’s accidental discovery that cells divide about 80 times and then slow down and stop. This is now known as the “Hayflick Limit.” We now now know know why our our cells cells stop divi dividing ding.. It turns turns out that there is a mechanism built into each cell, a sort of clock that limits the number of times a cell can divide. It is controlled by something called a telomere, which is a stretch of DNA that occurs at the end of every chromosome.i

The Cycle of A Cell Most of the cells in your body have the ability to reproduce at will. But, contrary to a century of scientific doctrine, we now know that each daughter cell does not receive a complete copy copy of the parent cell’s DNA. Each time a cell divides, a tiny portion of the DNA, a portion of the telomere at the end of the chromosome is lost. Each new generation of cells have slightly shorter telomeres than their parents. In fact, you can judge the age of a cell by measuring


•


2

sive to correct high homocysteine levels with the following nutrient protocol. You can get these nutrients at any health food store. • Vita Vitamin min B12 B12 500 500 mcg mcg • Folic Acid 800 mcg • Vita Vitamin min B6 B6 25 mg • Riboflavin (B2) 25 mg • TMG (trimethylglycine) 500 mg

When Whe n enough enough cell cellss act act old, old, they they creat createe a ripple ripple effe effect. ct. Eventu Eventuall ally, y, the damage progresses to the point that your body can no longer defend itself and succumbs to disease. There are strategies that you can put into play today that will help slo slow w the shor shorteni tening ng of of your your telom telomeres eres,, thus thus slowing slowing the actual aging process.

Keep Your Homocysteine Level In A Healthy Range Homocysteine is an amino acid that accumulates in the tissues. If you have high levels of this dangerous substance in your bloodstream, you greatly increase your risk of heart disease, Alzheimer’s disease, Parkinson’s disease, and impotence. It’s no coincidence that homocysteine levels have been correlated with the most common degenerative diseases of aging. Researchers have discovered that high homocysteine tripled the amount of telomere length that was lost during cell division.iii This is tripling the speed at which your body is aging. There is more reason than ever to closely monitor and correct high homocysteine levels in the blood. Your doctor can measure homocysteine with a simple blood test. It is very easy and inexpen-

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telomeric length. When the telomere gets sufficiently short, the cell enters programmed cell death. So the telomere serves as a counter, or clock, for the cell. But the telomere does more than just tell time. As the telomere shortens, it changes the behavior of the cell. Cells with shorter telomeres begin to slow down. The signals that control hormone output and immune function become weaker. They start to act old. ii

sive to correct high homocysteine levels with the following nutrient protocol. You can get these nutrients at any health food store. • Vita Vitamin min B12 B12 500 500 mcg mcg • Folic Acid 800 mcg • Vita Vitamin min B6 B6 25 mg • Riboflavin (B2) 25 mg • TMG (trimethylglycine) 500 mg

When Whe n enough enough cell cellss act act old, old, they they creat createe a ripple ripple effe effect. ct. Eventu Eventuall ally, y, the damage progresses to the point that your body can no longer defend itself and succumbs to disease. There are strategies that you can put into play today that will help slo slow w the shor shorteni tening ng of of your your telom telomeres eres,, thus thus slowing slowing the actual aging process.

Keep Your Homocysteine Level In A Healthy Range Homocysteine is an amino acid that accumulates in the tissues. If you have high levels of this dangerous substance in your bloodstream, you greatly increase your risk of heart disease, Alzheimer’s disease, Parkinson’s disease, and impotence. It’s no coincidence that homocysteine levels have been correlated with the most common degenerative diseases of aging. Researchers have discovered that high homocysteine tripled the amount of telomere length that was lost during cell division.iii This is tripling the speed at which your body is aging. There is more reason than ever to closely monitor and correct high homocysteine levels in the blood. Your doctor can measure homocysteine with a simple blood test. It is very easy and inexpen-

3


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Resetting Your Biological Clock Many argue that aging is a natural phenomenon that should be accepted as the natural order of things. Aging may be normal, but that doesn’t make it desirable. There can be no doubt that the aging process is the root of serious health problems. We die because we get sick. But we get sick because we get old. New technology that can rebuild the telomere and reset the biological clock now appears tantalizingly close. It turns out that our bodies already hold the answer. We are all born with the capacity to make an enzyme called telomerase. It can rebuild the telomere at each cell division so that the new daughter cells will behave no older than the parent cell. We all have the gene for this enzyme, but the gene is switched off. About a decade ago, a team of American scientists cloned the gene for human telomerase.

Eternal Youth A biotec biotechnol hnology ogy com company pany cal called led Geron Geron Cor Corpora poration tion,, owns owns the the patent for telomerase. It is leading the research on the use of telomerase as an anti-aging therapy. (It is also researching the development of telomerase inhibitors as a cancer treatment. If a cancer cell could have its telomerase turned off, it would grow old and die like a normal cell.) So far, the results of research on telomerase as an anti-aging therapy are extremely encouraging. By inserting a gene for telomerase into aging cells, it is possible to restore the shortened telomeres to lengths more typical of younger cells. Geron has taken cells from old mice and restored their telomeres to youthful lengths. These cells looked and acted in every way like young cells. And now last summer,

5


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•


4

they succeeded in changing a tissue culture of old human skin into youthful skin with telomerase. Imagine if all the cells in your body functioned the way they did when you were thir thirty, ty, you you woul wouldn’t dn’t see the the kind kind of of degener degenerativ ativee conconditions that are characteristic of aging. Your bones and joints would remain strong and your skin supple. Your immune function would remain vigilant and your heart vigorous. Everything we currently associate with aging: heart disease, arthritis, hearing loss, failing eyesight, Alzheimer’s disease and osteoporosis could become as rare in 70-year-olds as they are in 30-yearolds. You simply will not age. But before we can create eternally youthful bodies, we have to consider safety. One major concern is that the stimulation of telomerase could trigger or promote cancer. Abnormal presence of telomerase is seen in the development of cancer. The University of Texas and Geron have both tested telomererestored cells. Cells were monitored for cancer development. The immortalized cells were even exposed to cancer causing proteins to see if they could provoke cancerous behavior. All of the cells were found to be stable and cancer-free. iv The research continues to look positive. It seems that anti-aging therapy via telomerase as an option for humans is drawing nearer. I would be surprised if we don’t see some human applications within 10 years.

Slow The Aging Process But in the meantime, your cells are dividing, your telomeres are shortening and you are getting older.


•


6

Resetting Your Biological Clock Many argue that aging is a natural phenomenon that should be accepted as the natural order of things. Aging may be normal, but that doesn’t make it desirable. There can be no doubt that the aging process is the root of serious health problems. We die because we get sick. But we get sick because we get old. New technology that can rebuild the telomere and reset the biological clock now appears tantalizingly close. It turns out that our bodies already hold the answer. We are all born with the capacity to make an enzyme called telomerase. It can rebuild the telomere at each cell division so that the new daughter cells will behave no older than the parent cell. We all have the gene for this enzyme, but the gene is switched off. About a decade ago, a team of American scientists cloned the gene for human telomerase.

Eternal Youth A biotec biotechnol hnology ogy com company pany cal called led Geron Geron Cor Corpora poration tion,, owns owns the the patent for telomerase. It is leading the research on the use of telomerase as an anti-aging therapy. (It is also researching the development of telomerase inhibitors as a cancer treatment. If a cancer cell could have its telomerase turned off, it would grow old and die like a normal cell.) So far, the results of research on telomerase as an anti-aging therapy are extremely encouraging. By inserting a gene for telomerase into aging cells, it is possible to restore the shortened telomeres to lengths more typical of younger cells. Geron has taken cells from old mice and restored their telomeres to youthful lengths. These cells looked and acted in every way like young cells. And now last summer,

5


•


Fortunately, there are strategies that you can put into play immediately that will help slow the shortening of your telomeres, thus slowing the aging process. • Keep homocysteine in a healthy range • Take Vitamin C The well-known scientist Linus Pauling was the first to claim that vitamin vita min C cou could ld extend extend you yourr life. life. Dr. Dr. Paulin Paulingg took took between between 12,0 12,000 00 and 18,000 mg of vitamin C every day for years and lived to the ripe old age of 93. Pauling’s theory was dismissed until the 1980’s when scientists discovered that antioxidants could protect cells from oxidative damage. The free radical theory of aging became popular. Vitamin Vita min C was foun found d to be be among among the nutri nutrients ents that prot protect ect cell cellss from free radicals. But oxidative damage to cells can be repaired. It is the oxidative damage to telemeres that is not repaired. This results in further shortening of telomeres. This very specific effect of free radical damage helps drive the aging process. In 1998, a Japanese study tested vitamin C’s effect on telomeres. It was found that raising the level of vitamin C in the cells could slow down the loss of telomeres up to 62%. v The Recommended Daily Allowance of 60 mg of Vitamin C per day is not enough to slow telomere loss. And Pauling’s mega-doses aren’t necessary. An effective dose of vitamin C for the purposes of preserving telomeric length is 500-1500 mg, twice a day.

7


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they succeeded in changing a tissue culture of old human skin into youthful skin with telomerase. Imagine if all the cells in your body functioned the way they did when you were thir thirty, ty, you you woul wouldn’t dn’t see the the kind kind of of degener degenerativ ativee conconditions that are characteristic of aging. Your bones and joints would remain strong and your skin supple. Your immune function would remain vigilant and your heart vigorous. Everything we currently associate with aging: heart disease, arthritis, hearing loss, failing eyesight, Alzheimer’s disease and osteoporosis could become as rare in 70-year-olds as they are in 30-yearolds. You simply will not age. But before we can create eternally youthful bodies, we have to consider safety. One major concern is that the stimulation of telomerase could trigger or promote cancer. Abnormal presence of telomerase is seen in the development of cancer. The University of Texas and Geron have both tested telomererestored cells. Cells were monitored for cancer development. The immortalized cells were even exposed to cancer causing proteins to see if they could provoke cancerous behavior. All of the cells were found to be stable and cancer-free. iv The research continues to look positive. It seems that anti-aging therapy via telomerase as an option for humans is drawing nearer. I would be surprised if we don’t see some human applications within 10 years.

Slow The Aging Process But in the meantime, your cells are dividing, your telomeres are shortening and you are getting older.


•


6

Your Yo ur Yo Yout uthf hful ul Mi Mind nd Did you know that too much stress kills brain cells? Research is showing stress to be one of the leading causes of mental deterioration with aging. For most people, effective anti-aging has to address living better as we age not necessarily living longer. We want to retain the independence and abilities of our youth. For a lot of elders, loss of mental capacity is the most frightening symptom of aging. Fortunately, the loss of mental faculties is not inevitable. The most important thing you must do to keep your brain healthy and your mind sharp is avoid excess stress.

The Physiology of Stress Stress has serious physiological effects on the body. When you are stressed, your body produces a hormone called cortisol. In moderate amounts, cortisol is not very harmful. But cortisol is secreted excessively in response to chronic stress. In these larger amounts, cortisol is extremely toxic. Cortisol actually kills and disables your brain cells. Over your life your life span, span, cortiso cortisoll ruins ruins your your brai brains ns “bioc “biochemi hemical cal integ integrity” rity”.. Chronic exposure to cortisol causes the mental haziness, forgetfulness, and confusion that is associated with aging. In anti-aging, most hormonal manipulation involves supporting declining levels. Almost all hormone levels fall as you age. Cortisol is one of the very few exceptions. Cortisol actually rises as you grow older. To regain and keep a youthful mind, you must lower the cortisol levels in your body.


•


8

Fortunately, there are strategies that you can put into play immediately that will help slow the shortening of your telomeres, thus slowing the aging process. • Keep homocysteine in a healthy range • Take Vitamin C The well-known scientist Linus Pauling was the first to claim that vitamin vita min C cou could ld extend extend you yourr life. life. Dr. Dr. Paulin Paulingg took took between between 12,0 12,000 00 and 18,000 mg of vitamin C every day for years and lived to the ripe old age of 93. Pauling’s theory was dismissed until the 1980’s when scientists discovered that antioxidants could protect cells from oxidative damage. The free radical theory of aging became popular. Vitamin Vita min C was foun found d to be be among among the nutri nutrients ents that prot protect ect cell cellss from free radicals. But oxidative damage to cells can be repaired. It is the oxidative damage to telemeres that is not repaired. This results in further shortening of telomeres. This very specific effect of free radical damage helps drive the aging process. In 1998, a Japanese study tested vitamin C’s effect on telomeres. It was found that raising the level of vitamin C in the cells could slow down the loss of telomeres up to 62%. v The Recommended Daily Allowance of 60 mg of Vitamin C per day is not enough to slow telomere loss. And Pauling’s mega-doses aren’t necessary. An effective dose of vitamin C for the purposes of preserving telomeric length is 500-1500 mg, twice a day.

7


•


Attainin Atta ining g Your Your Menta Mentall Clarit Clarity y You can lowe lowerr levels levels of corti cortisol sol in the the body body by by reducin reducingg stress. stress. Here are some simple, but effective ideas to lessen stress:

Your Yo ur Yo Yout uthf hful ul Mi Mind nd Did you know that too much stress kills brain cells? Research is showing stress to be one of the leading causes of mental deterioration with aging. For most people, effective anti-aging has to address living better as we age not necessarily living longer. We want to retain the independence and abilities of our youth. For a lot of elders, loss of mental capacity is the most frightening symptom of aging. Fortunately, the loss of mental faculties is not inevitable. The most important thing you must do to keep your brain healthy and your mind sharp is avoid excess stress.

The Physiology of Stress Stress has serious physiological effects on the body. When you are stressed, your body produces a hormone called cortisol. In moderate amounts, cortisol is not very harmful. But cortisol is secreted excessively in response to chronic stress. In these larger amounts, cortisol is extremely toxic. Cortisol actually kills and disables your brain cells. Over your life your life span, span, cortiso cortisoll ruins ruins your your brai brains ns “bioc “biochemi hemical cal integ integrity” rity”.. Chronic exposure to cortisol causes the mental haziness, forgetfulness, and confusion that is associated with aging. In anti-aging, most hormonal manipulation involves supporting declining levels. Almost all hormone levels fall as you age. Cortisol is one of the very few exceptions. Cortisol actually rises as you grow older. To regain and keep a youthful mind, you must lower the cortisol levels in your body.



8

and mind go hand and hand. With thes thesee techniq techniques, ues, you sho should uld be able able to to reduce reduce your stre stress. ss. This eliminates the number one age associated killer of brain cells. It will help you keep a sharp sharp and and focus focused ed mind mind at at any age.

Use breathing techniques: Breathing techniques can help to calm your body. They aid in releasing stress. Once you learn the techniques, you can do them anywhere. Let it out: Writing down problems or talking about them is also effective stress management. Write down your problem and how you feel about it. You will be surprised at the therapeutic effect.

•

Brain Shrinks With Age 102 100 98 96

Talking through your problems can also help. An understanding friend or a family member can make a good listener. Do your favorite thing: Most people have one thing in life that they like to do most. It is the thing that relaxes you and lets you forg forget et about about you yourr worries worries.. Golfin Golfing, g, painti painting, ng, garde gardening ning,, visitin visitingg a special place, or having a picnic can release your mind of the stress of daily living. Set aside time for your favorite thing and do it more often.

94 92

% 90 E Z 88 I S N 86 I A 84 R B 82

20

40

AGE

60

80

Resource: American Foundation for Aging Research: Neurobiology of Aging Information What Physical Changes Happen to the Brain?

Meditate: Meditation can be very simple. It is a time that you use to focus within yourself. Sit or lie in a comfortable position. Listen to your breathing and follow it. Or repeat a word or short phrase that means something. You can speak it or just think it in a rhythm that is comfortable. Clear your mind of worries, and focus on relaxing.

Take 10 or 15 minutes out of your day to do this. You can even meditate as you lie in bed at night. It will be time well spent. Take care of yourself: Eat a healthy diet and make sure to exercise. Also remember to take your multivitamin. A healthy body

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•


10

Attainin Atta ining g Your Your Menta Mentall Clarit Clarity y You can lowe lowerr levels levels of corti cortisol sol in the the body body by by reducin reducingg stress. stress. Here are some simple, but effective ideas to lessen stress:

and mind go hand and hand. With thes thesee techniq techniques, ues, you sho should uld be able able to to reduce reduce your stre stress. ss. This eliminates the number one age associated killer of brain cells. It will help you keep a sharp sharp and and focus focused ed mind mind at at any age.

Use breathing techniques: Breathing techniques can help to calm your body. They aid in releasing stress. Once you learn the techniques, you can do them anywhere. Let it out: Writing down problems or talking about them is also effective stress management. Write down your problem and how you feel about it. You will be surprised at the therapeutic effect.

Brain Shrinks With Age 102 100 98 96

Talking through your problems can also help. An understanding friend or a family member can make a good listener. Do your favorite thing: Most people have one thing in life that they like to do most. It is the thing that relaxes you and lets you forg forget et about about you yourr worries worries.. Golfin Golfing, g, painti painting, ng, garde gardening ning,, visitin visitingg a special place, or having a picnic can release your mind of the stress of daily living. Set aside time for your favorite thing and do it more often.

94 92

% 90 E Z 88 I S N 86 I A 84 R B 82

20

40

AGE

60

80

Resource: American Foundation for Aging Research: Neurobiology of Aging Information What Physical Changes Happen to the Brain?

Meditate: Meditation can be very simple. It is a time that you use to focus within yourself. Sit or lie in a comfortable position. Listen to your breathing and follow it. Or repeat a word or short phrase that means something. You can speak it or just think it in a rhythm that is comfortable. Clear your mind of worries, and focus on relaxing.

Take 10 or 15 minutes out of your day to do this. You can even meditate as you lie in bed at night. It will be time well spent. Take care of yourself: Eat a healthy diet and make sure to exercise. Also remember to take your multivitamin. A healthy body

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Muscle is Youth

The Closest Thing To An Anti-Aging Pill

Did you know that you are losing about 3 pounds of muscle Most people don’t. They don’t notice because mass per decade? Most the lost muscle is replaced with fat. Today, you will see why you should be concerned over this loss of muscle — and the best way to get it back.

The most powerful tool for building muscle is exercise. The right exercise can reverse just about every change of aging. Each of the following symptoms of aging can be reversed through a specific exercise.

Loss of muscle is interconnected with the mechanisms by which whic h you you age. age. The amo amount unt of of muscle muscle you have is a key key factor factor in the regulation of other metabolic activities. Muscle is important in maintaining each of these body functions: • Supporting bones • Reducing osteoarthritis • Aidi Aiding ng in sexu sexual al heal health th • Thyroid hormone production • Maintaining adrenal production • Controlling metabolic rate • Stimulating human growth hormone • Preventing chronic aches (like back pain) A Finnis Finnish h study study call called, ed, the the Evergre Evergreen en Projec Project, t, is cur currentl rentlyy studystudying the effects of muscle on the aging process. Men and women between the ages of 65 and 94 are participating in the study. The on-going study is proving wide-ranging benefits that go hand in hand with muscle building. The participants with the most muscle are experiencing better mental function, fewer chronic illnesses, and longer life spans. vi

SYMPTOM OF AGING

BENEFIT OF EXERCISE

Increased susceptibility to disease

Improves immune system function

Loss of muscle and increased body fat

Aids in loss of fat fat and builds muscle

Increased risk of a cardiac event (heart attack, stroke)

Lowers blood pressure, improves circulation, lowers cholesterol

Slowing of mental function and alertness

Improves reaction times and mental clarity

Insomnia

Improves quality of sleep

Depression

Relieves stress, improves self-esteem and outlook

Immobility and susceptibility to falls

Improves balance and coordination

10

Resource: Klatz, R. Hormones of Youth 1999

These benefits have been shown to occur regardless of the age of the participants. The Human Nutritional Research Center on Aging at Tufts University studied the effect of muscle building exercise in elders. They were between the ages of 63 and 98. Most required walking walk ing aids aids or or were were in whee wheelch lchairs airs.. Over 10 weeks, a marked increase in muscle strength was reported. The participants also noticed improved stamina and stability. Many participants were able to walk unaided after the muscle building exercise therapy. vii

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Muscle is Youth

The Closest Thing To An Anti-Aging Pill

Did you know that you are losing about 3 pounds of muscle Most people don’t. They don’t notice because mass per decade? Most the lost muscle is replaced with fat. Today, you will see why you should be concerned over this loss of muscle — and the best way to get it back.

The most powerful tool for building muscle is exercise. The right exercise can reverse just about every change of aging. Each of the following symptoms of aging can be reversed through a specific exercise.

Loss of muscle is interconnected with the mechanisms by which whic h you you age. age. The amo amount unt of of muscle muscle you have is a key key factor factor in the regulation of other metabolic activities. Muscle is important in maintaining each of these body functions: • Supporting bones • Reducing osteoarthritis • Aidi Aiding ng in sexu sexual al heal health th • Thyroid hormone production • Maintaining adrenal production • Controlling metabolic rate • Stimulating human growth hormone • Preventing chronic aches (like back pain) A Finnis Finnish h study study call called, ed, the the Evergre Evergreen en Projec Project, t, is cur currentl rentlyy studystudying the effects of muscle on the aging process. Men and women between the ages of 65 and 94 are participating in the study. The on-going study is proving wide-ranging benefits that go hand in hand with muscle building. The participants with the most muscle are experiencing better mental function, fewer chronic illnesses, and longer life spans. vi

SYMPTOM OF AGING

BENEFIT OF EXERCISE

Increased susceptibility to disease

Improves immune system function

Loss of muscle and increased body fat

Aids in loss of fat fat and builds muscle

Increased risk of a cardiac event (heart attack, stroke)

Lowers blood pressure, improves circulation, lowers cholesterol

Slowing of mental function and alertness

Improves reaction times and mental clarity

Insomnia

Improves quality of sleep

Depression

Relieves stress, improves self-esteem and outlook

Immobility and susceptibility to falls

Improves balance and coordination

Resource: Klatz, R. Hormones of Youth 1999

These benefits have been shown to occur regardless of the age of the participants. The Human Nutritional Research Center on Aging at Tufts University studied the effect of muscle building exercise in elders. They were between the ages of 63 and 98. Most required walking walk ing aids aids or or were were in whee wheelch lchairs airs.. Over 10 weeks, a marked increase in muscle strength was reported. The participants also noticed improved stamina and stability. Many participants were able to walk unaided after the muscle building exercise therapy. vii

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Forget Wear and Tear Exercise

The Anti-Stress Hormone

Of all the benefits of exercise, maintaining youthful muscle mass is the most generally health enhancing. This is particularly evident in elders. Building muscle keeps you young.

DHEA is often referred to as the “anti-stress hormone”. DHEA stands for dehydroepiandrosterone. Don’t let that tongue-twisting name bother you, everyone refers to it as DHEA. It is the most abundant product of the adrenal glands. DHEA is the precursor used by yourr body you body in in produ producin cingg sex sex hormo hormones nes lik likee testos testostero terone, ne, estr estroge ogen n and and progesterone. It is produced in large quantities in youth but its production dwindles with age.

Long endurance exercise is a waste of your time when you are trying to lose weight. This applies to anti-aging as well. Long duration exercise causes wear and tear on your body. Your joints become sore. Muscles are fatigued but not given the most effective signal for growth. Here are some strategies from sports training that have proven effective for building muscle in elders as well.

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Most hormones decline with age but cortisol, the stress hormone, actually increases with age. Cortisol then plays havoc on your body. Your body need not worry about long-term maintenance like building your immune system or laying down new bone or muscle when you are running from a lion.

Workk the lar large ge muscl musclee groups groups firs firstt (think (think legs and back back)) 4 Wor 4 Perform strength training exercises only 3 times a week 4 Perform the exercises at high intensity for short duration 4 Progressively increase your work load to stimulate

muscle growth

When Whe n you you are are under under stress stress cor cortiso tisoll tells tells your your body “jus “justt get through the moment, damn tomorrow.” Since it inhibits maintenance and repair, cortisol accelerates aging. It’s like burning your candles at both ends. DHEA is the natural counter to cortisol.

4 Use slow and smooth movements to prevent injury

You secr secrete ete DHEA DHEA when time timess are are good good when when you you are are well well feed, feed, secure and free of stressors. The more DHEA in your body, the less effect stress will have on you. The problem is your adrenal capacity to produce DHEA declines with age. Yet the modern environment stresses your body everyday. Cortisol is overproduced and aging is accelerated. Levels of sex hormones decrease as you age. DHEA boosts the production of sex hormones and creates a slew of health benefits. It is a crucial part of being youthful. Like hormones, DHEA declines with age.

13


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•


14

Forget Wear and Tear Exercise

The Anti-Stress Hormone

Of all the benefits of exercise, maintaining youthful muscle mass is the most generally health enhancing. This is particularly evident in elders. Building muscle keeps you young.

DHEA is often referred to as the “anti-stress hormone”. DHEA stands for dehydroepiandrosterone. Don’t let that tongue-twisting name bother you, everyone refers to it as DHEA. It is the most abundant product of the adrenal glands. DHEA is the precursor used by yourr body you body in in produ producin cingg sex sex hormo hormones nes lik likee testos testostero terone, ne, estr estroge ogen n and and progesterone. It is produced in large quantities in youth but its production dwindles with age.

Long endurance exercise is a waste of your time when you are trying to lose weight. This applies to anti-aging as well. Long duration exercise causes wear and tear on your body. Your joints become sore. Muscles are fatigued but not given the most effective signal for growth. Here are some strategies from sports training that have proven effective for building muscle in elders as well.

Most hormones decline with age but cortisol, the stress hormone, actually increases with age. Cortisol then plays havoc on your body. Your body need not worry about long-term maintenance like building your immune system or laying down new bone or muscle when you are running from a lion.

Workk the lar large ge muscl musclee groups groups firs firstt (think (think legs and back back)) 4 Wor 4 Perform strength training exercises only 3 times a week 4 Perform the exercises at high intensity for short duration 4 Progressively increase your work load to stimulate

muscle growth

When Whe n you you are are under under stress stress cor cortiso tisoll tells tells your your body “jus “justt get through the moment, damn tomorrow.” Since it inhibits maintenance and repair, cortisol accelerates aging. It’s like burning your candles at both ends. DHEA is the natural counter to cortisol.

4 Use slow and smooth movements to prevent injury

You secr secrete ete DHEA DHEA when time timess are are good good when when you you are are well well feed, feed, secure and free of stressors. The more DHEA in your body, the less effect stress will have on you. The problem is your adrenal capacity to produce DHEA declines with age. Yet the modern environment stresses your body everyday. Cortisol is overproduced and aging is accelerated. Levels of sex hormones decrease as you age. DHEA boosts the production of sex hormones and creates a slew of health benefits. It is a crucial part of being youthful. Like hormones, DHEA declines with age.

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Declining DHEA People with DHEA deficiency have been documented to experience: • Shortened life spans • Immune deficiencies • Inflammatory diseases • Cancer • Heart disease • Osteoporosis • Depression • Cognitive decline • Aged appe appeara arance nce


14

People with higher levels of DHEA experience: • Less stress • Enhanced energy • A boost boost in in immune immune syste system m functi function on • Reduced body fat • Increased libido • Sharper memory • Halt in wrinkles and signs of physical aging x

You can lowe lowerr your your corti cortisol sol leve levels ls by by reduci reducing ng stress stress..

Researchers found that those with the highest levels of DHEA performed better on both the cognitive and physical assessments. Study authors admitted that those with higher levels of DHEA seemed younger. viii

The Benefits of DHEA The rate of DHEA decline is surprising. By the time you are 65 years old, you’ll only have about 10% of the DHEA that you had when you were 20.ix


•

You can rais raisee your your level levelss two way ways: s: 1) by reducing levels of Cortisol, and by 2) DHEA supplementation.

A 1998 1998 study study publ publishe ished d in the Journal of the American studied DHEA’s effects on aging. People between Geriatric Society studied the ages of 60 and 80 were tested for DHEA levels. The participants also took cognitive and strength tests.

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I use DHEA at my Institute for Healthy Aging . DHEA therapy has successfully treated many of my patients who suffer from lack of energy, depression, and chronic fatigue syndrome. It is important for you to get your DHEA levels checked. Your doc doctor tor can can perfor perform m the the simple simple test. test. You Youthfu thfull levels levels of of DHEA DHEA for for men range from 400 to 560. For women, levels should range from 350 to 430. After your After your levels levels have been chec checked, ked, you can dete determin rminee optima optimall dosing. A common starting dose is 10 mg daily. DHEA is absorbed well and can can be be taken taken at at any time but best mim mimics ics the the natur natural al daily daily fluctuation when taken first thing in the morning.


•


16

Declining DHEA People with DHEA deficiency have been documented to experience: • Shortened life spans • Immune deficiencies • Inflammatory diseases • Cancer • Heart disease • Osteoporosis • Depression • Cognitive decline • Aged appe appeara arance nce

You can lowe lowerr your your corti cortisol sol leve levels ls by by reduci reducing ng stress stress..

Researchers found that those with the highest levels of DHEA performed better on both the cognitive and physical assessments. Study authors admitted that those with higher levels of DHEA seemed younger. viii

The Benefits of DHEA The rate of DHEA decline is surprising. By the time you are 65 years old, you’ll only have about 10% of the DHEA that you had when you were 20.ix


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Restoring Masculinity with Hormones You have hear heard d that that male male hormon hormones es declin declinee with with age. age. Recent Recent studies are revealing how and why, and their affect on aging. This is important because it gives men the option of reversing the decline, which whic h can can then then affect affect thei theirr aging. aging. The The contr controver oversial sial sub subject ject of femal femalee hormones will be tackled in the next section. We men men have have alway alwayss known known that that our our bodie bodiess dramati dramatical cally ly chang changee as we age. It wasn’t until recently science revealed that nearly all of these changes are intentionally “signaled” to occur by changing hormones. As you you get get older, older, genes turn on and and off, off, partl partlyy accord according ing to to a preprogrammed sequence and partly in response to your environment. Which genes are turned on determine hormone levels and they affect your metabolism and capabilities. They can even affect your physical form. It is the principle reason that you are physically different at 60 than you were at 18. Hormones also affect mood, memory, mental clarity and energy. The most important hormones for male health and masculinity are: • DHEA • Andr Androste ostenedi nedione one • Testosterone We all all know know that that testo testoster sterone one is the the hormon hormonee that that makes makes a man, a man. But this hormone does much more than that. Testosterone helps to control body fat, mood, energy, sexual desire, cognitive function, and aging. Testosterone doesn’t decline all of a sudden like female hormones do at menopause. The decline is gradual but over time,

17


• Less stress • Enhanced energy • A boost boost in in immune immune syste system m functi function on • Reduced body fat • Increased libido • Sharper memory • Halt in wrinkles and signs of physical aging x You can rais raisee your your level levelss two way ways: s: 1) by reducing levels of Cortisol, and by 2) DHEA supplementation.

A 1998 1998 study study publ publishe ished d in the Journal of the American studied DHEA’s effects on aging. People between Geriatric Society studied the ages of 60 and 80 were tested for DHEA levels. The participants also took cognitive and strength tests.

15

People with higher levels of DHEA experience:

•


I use DHEA at my Institute for Healthy Aging . DHEA therapy has successfully treated many of my patients who suffer from lack of energy, depression, and chronic fatigue syndrome. It is important for you to get your DHEA levels checked. Your doc doctor tor can can perfor perform m the the simple simple test. test. You Youthfu thfull levels levels of of DHEA DHEA for for men range from 400 to 560. For women, levels should range from 350 to 430. After your After your levels levels have been chec checked, ked, you can dete determin rminee optima optimall dosing. A common starting dose is 10 mg daily. DHEA is absorbed well and can can be be taken taken at at any time but best mim mimics ics the the natur natural al daily daily fluctuation when taken first thing in the morning.


•


16

just as profo profound. und. Tes Testost tosteron eronee levels levels are are at at their their peak peak in in your your twentwenties. By the time you reach 80, your testosterone levels decrease between 50% and 70%. xi Testosterone can: • Improve sexual performance • Promote libido • Stimulate muscle growth • Increase energy levels • Improve memory, mood and mental clarity • Build stronger bones • Keep urinary and reproductive systems healthy Before tinkering with testosterone, you should consult with your doctor. your doctor. Hav Havee all all of the male male hormo hormones nes liste listed d measur measured ed in your blood. Once you do that, it is possible to boost your own levels of male hormones including testosterone naturally.

Restoring Testosterone Naturally Because you make all of your sex hormones from DHEA, taking a DHEA supplement is often a good place to start. Note: DHEA is a hormone. Hormones always act as “double-edged swords”. Too little or too much can both be bad. Never take any hormone without having blood levels checked. The athletes call androstenedione, “andro”. Andro is the immediate precursor to testosterone. They use it as a sports performance and muscle building aid. It is effective but they don’t measure blood levels and they take too much. If they take too much, the excess is converted to estrogen. With the constant exposure to environmental estrogens, this is the last thing aging men need.


•


18

Restoring Masculinity with Hormones You have hear heard d that that male male hormon hormones es declin declinee with with age. age. Recent Recent studies are revealing how and why, and their affect on aging. This is important because it gives men the option of reversing the decline, which whic h can can then then affect affect thei theirr aging. aging. The The contr controver oversial sial sub subject ject of femal femalee hormones will be tackled in the next section. We men men have have alway alwayss known known that that our our bodie bodiess dramati dramatical cally ly chang changee as we age. It wasn’t until recently science revealed that nearly all of these changes are intentionally “signaled” to occur by changing hormones. As you you get get older, older, genes turn on and and off, off, partl partlyy accord according ing to to a preprogrammed sequence and partly in response to your environment. Which genes are turned on determine hormone levels and they affect your metabolism and capabilities. They can even affect your physical form. It is the principle reason that you are physically different at 60 than you were at 18. Hormones also affect mood, memory, mental clarity and energy. The most important hormones for male health and masculinity are: • DHEA • Andr Androste ostenedi nedione one • Testosterone We all all know know that that testo testoster sterone one is the the hormon hormonee that that makes makes a man, a man. But this hormone does much more than that. Testosterone helps to control body fat, mood, energy, sexual desire, cognitive function, and aging. Testosterone doesn’t decline all of a sudden like female hormones do at menopause. The decline is gradual but over time,

17


•


If you take “andro”, you must have blood levels checked. Research has shown that 5 to 10 mg is all men need to restore youthful levels. For many men, the preferred way to restore testosterone has been with the natural herb Tribulus. Tribulus terrestris has long been used to boost testosterone in Asia. It has been given to men who have weak muscle and sexual problems. It was reintroduced to the world by East German Olympic athletes. Tribulus gently boosts testosterone levels, which explains both its aphrodisiac effect and its sports performance enhancing effect. One study analyzed the effect of Tribulus on healthy men. The men experienced an average 30% increase in testosterone levels xii after just 5 days of oral supplementation. This is about the average rise in testosterone that men will experience. Use a starting dose of 250 mg once a day.

just as profo profound. und. Tes Testost tosteron eronee levels levels are are at at their their peak peak in in your your twentwenties. By the time you reach 80, your testosterone levels decrease between 50% and 70%. xi Testosterone can: • Improve sexual performance • Promote libido • Stimulate muscle growth • Increase energy levels • Improve memory, mood and mental clarity • Build stronger bones • Keep urinary and reproductive systems healthy Before tinkering with testosterone, you should consult with your doctor. your doctor. Hav Havee all all of the male male hormo hormones nes liste listed d measur measured ed in your blood. Once you do that, it is possible to boost your own levels of male hormones including testosterone naturally.

Restoring Testosterone Naturally Because you make all of your sex hormones from DHEA, taking a DHEA supplement is often a good place to start. Note: DHEA is a hormone. Hormones always act as “double-edged swords”. Too little or too much can both be bad. Never take any hormone without having blood levels checked. The athletes call androstenedione, “andro”. Andro is the immediate precursor to testosterone. They use it as a sports performance and muscle building aid. It is effective but they don’t measure blood levels and they take too much. If they take too much, the excess is converted to estrogen. With the constant exposure to environmental estrogens, this is the last thing aging men need.


•


18

Real Hormone Replacement in Women The hottest topic in medicine today is the issue of hormone replacement for women. It is important because your hormone levels decline and cause the changes of aging and menopause. These changes are entirely responsible for osteoporosis and at least partially responsible for the increased risk of heart disease in postmenopausal women. The matter is more popular than ever. Hormone replacement therapy (HRT) has been both praised and bashed in the media. The argument still rages, but no one seems to be focusing on the most important point in interpreting the recent studies. All of the studies about “HRT” that you have heard about recently did not test the effects of hormones. They are all trials of hormone mimicking drugs like synthetic estradiol derivatives and chemical medroxyprogesterone acetate. They are pharmaceutical concoctions made to mimic the effects of estrogen and progesterone respectively. xiii These things are drugs, not hormones. Since they have never been in your body, you are not replacing anything by taking them. Hormones are part of a complex, integrated system of control in nearly all body functions. Introducing an interfering drug into this delicate system was a dangerous experiment. Now, the largest trial done to date showed that they increase cancer risk and instead of decreasing risk risk of heart disease as claimed, they actually increased it. it. For instance, the drug combination in Prempro increased risk of blood clots by 100 %. The bad press about these drugs has given hormones themselves a bad name.

19


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•


20

If you take “andro”, you must have blood levels checked. Research has shown that 5 to 10 mg is all men need to restore youthful levels. For many men, the preferred way to restore testosterone has been with the natural herb Tribulus. Tribulus terrestris has long been used to boost testosterone in Asia. It has been given to men who have weak muscle and sexual problems. It was reintroduced to the world by East German Olympic athletes. Tribulus gently boosts testosterone levels, which explains both its aphrodisiac effect and its sports performance enhancing effect. One study analyzed the effect of Tribulus on healthy men. The men experienced an average 30% increase in testosterone levels xii after just 5 days of oral supplementation. This is about the average rise in testosterone that men will experience. Use a starting dose of 250 mg once a day.

Real Hormone Replacement in Women The hottest topic in medicine today is the issue of hormone replacement for women. It is important because your hormone levels decline and cause the changes of aging and menopause. These changes are entirely responsible for osteoporosis and at least partially responsible for the increased risk of heart disease in postmenopausal women. The matter is more popular than ever. Hormone replacement therapy (HRT) has been both praised and bashed in the media. The argument still rages, but no one seems to be focusing on the most important point in interpreting the recent studies. All of the studies about “HRT” that you have heard about recently did not test the effects of hormones. They are all trials of hormone mimicking drugs like synthetic estradiol derivatives and chemical medroxyprogesterone acetate. They are pharmaceutical concoctions made to mimic the effects of estrogen and progesterone respectively. xiii These things are drugs, not hormones. Since they have never been in your body, you are not replacing anything by taking them. Hormones are part of a complex, integrated system of control in nearly all body functions. Introducing an interfering drug into this delicate system was a dangerous experiment. Now, the largest trial done to date showed that they increase cancer risk and instead of decreasing risk risk of heart disease as claimed, they actually increased it. it. For instance, the drug combination in Prempro increased risk of blood clots by 100 %. The bad press about these drugs has given hormones themselves a bad name.

19


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Natural Hormone Replacement Real hormones are natural by definition. They are in your body as you read this, controlling and directing your physiology. They are the perfect instruments for performing these functions and present no danger to you. Tinkering with them without knowing what you’re doing though, is dangerous. Conventional medicine has insisted that you don’t need to have these hormones measured. Their position is that you can take the one-size-fits-all drugs or not. But hormone levels vary widely and are impossible to guess. Deciphering what to do about declines is complex and different in every woman. No woman should take a hormone without first having her hormone levels tested. If you hav havee problem problematic atic defi deficien ciencies cies,, take take the the real real hormon hormone, e, not not a drug drug substitute.


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20

Herbal Relief for Menopause There are three herbs for easing the symptoms of declining hormones and menopause are: • Dong Quai • Black Cohosh • Chaste Berry Dong Quai is an Asian herb that contains phytoestrogens. Phytoestrogens are estrogens found naturally in plants. Phytoestrogens work by occupying estrogen receptor sites in your body but many women I have treated with low progesterone also benefit from taking Dong Quai. Dong Quai also improves libido in women wome n with with declini declining ng sex sex hormon hormones. es.

500 mg in tablet form, twice a day. Real hormones are available at compounding pharmacists. A compo compoundi unding ng pharma pharmacist cist can prod produce uce a custom custom mixt mixture ure of natural hormones. They work with patients to develop a mixture that is uniquely suited for them. You can learn more about compounding pharmacists by visiting the International Academy of Compounding Pharmacist’s web site at www.iacprx.org at www.iacprx.org.. You will need a prescri prescriptio ption n for for these these natur natural al horm hormones ones.. But there are safe alternatives that gently affect hormone levels available without a prescription. You can find them at health food stores.

Black Cohosh is another plant that contains phytoestrogens. It has been used traditionally by Native Americans to treat menstrual cramping. Black Cohosh also occupies estrogen receptors. It is the best herbal treatment found to treat low estrogen caused mood swings and hot flashes.

250 mg in tablet form, three times a day. is another effective herb for menopausal sympChaste Berry is toms. It works by regulating pituitary hormones, which regulate estrogen, progesterone and testosterone. It is a gentle hormone balancer. Chaste Berry is used to relieve depression, insomnia and hot flashes associated with estrogen and progesterone decline. xiv 300 mg in tablet form once a day.

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Natural Hormone Replacement Real hormones are natural by definition. They are in your body as you read this, controlling and directing your physiology. They are the perfect instruments for performing these functions and present no danger to you. Tinkering with them without knowing what you’re doing though, is dangerous. Conventional medicine has insisted that you don’t need to have these hormones measured. Their position is that you can take the one-size-fits-all drugs or not. But hormone levels vary widely and are impossible to guess. Deciphering what to do about declines is complex and different in every woman. No woman should take a hormone without first having her hormone levels tested. If you hav havee problem problematic atic defi deficien ciencies cies,, take take the the real real hormon hormone, e, not not a drug drug substitute.

Herbal Relief for Menopause There are three herbs for easing the symptoms of declining hormones and menopause are: • Dong Quai • Black Cohosh • Chaste Berry Dong Quai is an Asian herb that contains phytoestrogens. Phytoestrogens are estrogens found naturally in plants. Phytoestrogens work by occupying estrogen receptor sites in your body but many women I have treated with low progesterone also benefit from taking Dong Quai. Dong Quai also improves libido in women wome n with with declini declining ng sex sex hormon hormones. es.

500 mg in tablet form, twice a day. Real hormones are available at compounding pharmacists. A compo compoundi unding ng pharma pharmacist cist can prod produce uce a custom custom mixt mixture ure of natural hormones. They work with patients to develop a mixture that is uniquely suited for them. You can learn more about compounding pharmacists by visiting the International Academy of Compounding Pharmacist’s web site at www.iacprx.org at www.iacprx.org.. You will need a prescri prescriptio ption n for for these these natur natural al horm hormones ones.. But there are safe alternatives that gently affect hormone levels available without a prescription. You can find them at health food stores.

Black Cohosh is another plant that contains phytoestrogens. It has been used traditionally by Native Americans to treat menstrual cramping. Black Cohosh also occupies estrogen receptors. It is the best herbal treatment found to treat low estrogen caused mood swings and hot flashes.

250 mg in tablet form, three times a day. is another effective herb for menopausal sympChaste Berry is toms. It works by regulating pituitary hormones, which regulate estrogen, progesterone and testosterone. It is a gentle hormone balancer. Chaste Berry is used to relieve depression, insomnia and hot flashes associated with estrogen and progesterone decline. xiv 300 mg in tablet form once a day.

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Reversing Human Aging In 1990, Dr. Daniel Rudman accomplished something that had never been done before. He reversed human aging. Wrinkles disappeared. Grey hair began turning black again. Energy levels soared. And seven seventy-y ty-yearear-old oldss had had resurge resurgence nce in sexua sexuall appetit appetite. e. He was investigating the effects of a pituitary protein called human growth hormone on healthy adults. Twelve men, ages 61 to 81 volunteered for the trial. They received injections of human growth hormone for 6 months. As we we age age our our skin skin grows grows thinne thinner, r, we lose mus muscle cle and bone bone and and turn to fat. The men in the study grew thicker skin, developed bigger muscles and denser bones and lost fat. On average, the participants experienced: • 14.4% decrease in fat tissue mass • 8.8 % rise in lean body mass • 7.1% increase in skin thickness • 1.6% rise in bone density When Rudman’ When Rudman’ss study study was was publis published hed in in the New England Journal of Medicine , he wrote: “The effects of six months of human growth hormone on lean body mass and adipose-tissue mass were equivalent in magnitude to the changes incurred during 10 to 20 years of aging.” xv

Why We We Call Call It the the Fount Fountain ain of You Youth th HGH (human growth hormone) is the most powerful weapon in weapon in an anti anti-agi -aging ng physic physician’ ian’ss arsenal arsenal.. Your Your body body produ produces ces high amounts of HGH as a child but the production declines throughout your adult life. This orchestrated decline causes and con23


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22

trols many of the changes of aging. When you reverse the decline of HGH, you reverse many of the consequences of aging. Several other studies have now confirmed Dr. Rudman’s findings. The benefits of HGH include: • Increased energy • Enhanced sexual performance • Muscle gain • Fat loss • Stronger bones • Diminished wrinkles • Improved immune function • Enhanced mood • Decreased cholesterol • Improved vision

Percentage of Patient Improvement with HGH Therapy 80

70

60

50

40

30

20

10

0

S t r e n g t h

S e x D r i v e

E n d u r a n c e

F a t L o s s

E n e r g y

Resource: Cenegenics Medical Institute

HGH is now FDA approved for growth hormone deficient adults but conventional medicine has been on the fence when it comes to HGH. The concern is that we don’t know its effect with long-term use. But the results of a recent 10-year study, which concluded last summer, helped to prove its long-term effectiveness. Researchers analyzed a group of men receiving HGH for ten years. year s. That That group group was com compare pared d to a group group of of men men of the same same age who did not receive HGH. The men receiving HGH had more lean muscle mass, less fat, more energy, and more stable emotional health than the men who did not receive HGH. The benefits seen in the many short-term studies on HGH continued throughout the 10 years, without any negative side effects. The men taking HGH had appeared to turn back the clock, safely. xvi


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Reversing Human Aging In 1990, Dr. Daniel Rudman accomplished something that had never been done before. He reversed human aging. Wrinkles disappeared. Grey hair began turning black again. Energy levels soared. And seven seventy-y ty-yearear-old oldss had had resurge resurgence nce in sexua sexuall appetit appetite. e. He was investigating the effects of a pituitary protein called human growth hormone on healthy adults. Twelve men, ages 61 to 81 volunteered for the trial. They received injections of human growth hormone for 6 months. As we we age age our our skin skin grows grows thinne thinner, r, we lose mus muscle cle and bone bone and and turn to fat. The men in the study grew thicker skin, developed bigger muscles and denser bones and lost fat. On average, the participants experienced: • 14.4% decrease in fat tissue mass • 8.8 % rise in lean body mass • 7.1% increase in skin thickness • 1.6% rise in bone density When Rudman’ When Rudman’ss study study was was publis published hed in in the New England Journal of Medicine , he wrote: “The effects of six months of human growth hormone on lean body mass and adipose-tissue mass were equivalent in magnitude to the changes incurred during 10 to 20 years of aging.” xv

Why We We Call Call It the the Fount Fountain ain of You Youth th HGH (human growth hormone) is the most powerful weapon in weapon in an anti anti-agi -aging ng physic physician’ ian’ss arsenal arsenal.. Your Your body body produ produces ces high amounts of HGH as a child but the production declines throughout your adult life. This orchestrated decline causes and con23


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Restore Your Youth

trols many of the changes of aging. When you reverse the decline of HGH, you reverse many of the consequences of aging. Several other studies have now confirmed Dr. Rudman’s findings. The benefits of HGH include: • Increased energy • Enhanced sexual performance • Muscle gain • Fat loss • Stronger bones • Diminished wrinkles • Improved immune function • Enhanced mood • Decreased cholesterol • Improved vision

Percentage of Patient Improvement with HGH Therapy 80

70

60

50

40

30

20

10

0

S t r e n g t h

S e x D r i v e

E n d u r a n c e

F a t L o s s

Resource: Cenegenics Medical Institute

HGH is now FDA approved for growth hormone deficient adults but conventional medicine has been on the fence when it comes to HGH. The concern is that we don’t know its effect with long-term use. But the results of a recent 10-year study, which concluded last summer, helped to prove its long-term effectiveness. Researchers analyzed a group of men receiving HGH for ten years. year s. That That group group was com compare pared d to a group group of of men men of the same same age who did not receive HGH. The men receiving HGH had more lean muscle mass, less fat, more energy, and more stable emotional health than the men who did not receive HGH. The benefits seen in the many short-term studies on HGH continued throughout the 10 years, without any negative side effects. The men taking HGH had appeared to turn back the clock, safely. xvi


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Now that you have learned techniques, it is time to put them into action.

Eating more protein: When you eat high amounts of protein, yourr HGH you HGH levels levels actu actuall allyy rise. rise. This This is a mild mild elevat elevation, ion, but none the less, it is effective.

Here is the 6-week Anti-Aging program to get you started. You will start with something simple and easy to do. Every week you will add a new Anti-aging technique. Continue with all of the techniques to ensure a healthier and younger you for the year to come.

HGH injections: HGH can only be given through injections.

— WEEK 1 ————————————————

Take Anti-aging vitamins: You can slow the cellular aging process with certain vitamins.

HGH has to be prescribed by a doctor. To be used safely you must have your blood levels checked. And you should only deal with a doctor who is familiar with HGH.

Each time a cell divides, a tiny portion of the DNA, or telomere at the end of the chromosome is lost. When the telomere shortens, the cell acts older. You can slow the shortening of your telomeres, thus slowing the actual aging process.

Once a doctor has established blood levels, patients inject themselves. It now comes in a handy self-injection cartridge without needles. It’s typically used in patients from 35 to 95 years old. Some use it in short cycles like athletes. Others elect more long-term inter vention venti on in the aging aging proc process. ess.

Take homocysteine-lowering supplements. Homocysteine is an amino acid that triples the amount of telomere length lost during cell division.

There have been some remarkable changes. Patients come in flabby and frail, and in a matter of weeks, are strong, healthy and active.

24

Your Yo ur 6 We Week ek An Anti ti-A -Agi ging ng Pl Plan an

I have researched the effectiveness of HGH through my Institute for Health Healthyy Aging. Aging.

Perform strenuous exercises: Strenuous exercise also increases levels of HGH in your body. I’m talking about gut-wrenching exercises here, like heavy squats and dead lifts. This is not a tip for the faint of heart.

E n e r g y

• Vita Vitamin min B12 500 500 mcg mcg • Folic Acid 800 mcg • Vitamin B6 25 mg • Riboflavin (B2) 25 mg • TMG (trimethylglycine) 500 mg Vitamin Vita min C slo slows ws the the loss loss of of telomer telomeres. es. Vitam Vitamin in C also also prev prevents ents damage to telomeres by free radicals. Vitamin Vita min C 100 10000 mg, mg, twice twice a day. day.

25


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•


26

Restore Your Youth

Your Yo ur 6 We Week ek An Anti ti-A -Agi ging ng Pl Plan an

I have researched the effectiveness of HGH through my Institute for Health Healthyy Aging. Aging.

Now that you have learned techniques, it is time to put them into action.

Eating more protein: When you eat high amounts of protein, yourr HGH you HGH levels levels actu actuall allyy rise. rise. This This is a mild mild elevat elevation, ion, but none the less, it is effective.

Here is the 6-week Anti-Aging program to get you started. You will start with something simple and easy to do. Every week you will add a new Anti-aging technique. Continue with all of the techniques to ensure a healthier and younger you for the year to come.

Perform strenuous exercises: Strenuous exercise also increases levels of HGH in your body. I’m talking about gut-wrenching exercises here, like heavy squats and dead lifts. This is not a tip for the faint of heart. HGH injections: HGH can only be given through injections.

— WEEK 1 ————————————————

Take Anti-aging vitamins: You can slow the cellular aging process with certain vitamins.

HGH has to be prescribed by a doctor. To be used safely you must have your blood levels checked. And you should only deal with a doctor who is familiar with HGH.

Each time a cell divides, a tiny portion of the DNA, or telomere at the end of the chromosome is lost. When the telomere shortens, the cell acts older. You can slow the shortening of your telomeres, thus slowing the actual aging process.

Once a doctor has established blood levels, patients inject themselves. It now comes in a handy self-injection cartridge without needles. It’s typically used in patients from 35 to 95 years old. Some use it in short cycles like athletes. Others elect more long-term inter vention venti on in the aging aging proc process. ess.

Take homocysteine-lowering supplements. Homocysteine is an amino acid that triples the amount of telomere length lost during cell division.

There have been some remarkable changes. Patients come in flabby and frail, and in a matter of weeks, are strong, healthy and active.

• Vita Vitamin min B12 500 500 mcg mcg • Folic Acid 800 mcg • Vitamin B6 25 mg • Riboflavin (B2) 25 mg • TMG (trimethylglycine) 500 mg Vitamin Vita min C slo slows ws the the loss loss of of telomer telomeres. es. Vitam Vitamin in C also also prev prevents ents damage to telomeres by free radicals. Vitamin Vita min C 100 10000 mg, mg, twice twice a day. day.

25


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26

4 Progressively increase your work load to stimulate

— WEEK 2 ————————————————

Apply stress-reducing techniques: Your body produces the hormone cortisol under stress. In larger amounts, cortisol is destructive. Cortisol kills brain cells.

You can lowe lowerr cortis cortisol ol by by reducin reducingg stress. stress. Appl Applyy these these simple simple techniques to lower your stress: Breathing techniques: Breathing techniques can help to calm yourr body. you body. Dr. Dr. Andrew Andrew Weil has som somee very very good good breat breathing hing inst instruc ruc-tion tapes. You can learn more by visiting his website at www.DrWeil. com. Let it out: Write down worries or talk about them with a friend, family member, or therapist. Do your favorite thing: Make time to do an activity that relaxes you, such as a hobby, and forget about your worries. Meditate: Meditation can be very simple. It is a time that you use to focu focuss within within yours yourself. elf. Tak Takee 10 or 15 15 minute minutess out out of you yourr day to do this.

— WEEK 3 ————————————————

Begin anti-aging exercise routine: You lose muscle as you age. The amo amount unt of of muscl musclee you you have have is key in the the regula regulation tion of aging. The best way to build youthful muscle is with the right kind of exercise.

muscle growth 4 Use slow and smooth movements to prevent injury

— WEEK 4 ————————————————

Begin to change your diet: Restricting calorie intake is a reliable way to extend life span. It works in every animal model. Caloric restriction slows the rate of cell division. Here are some strategies that will stop you from overeating and help you to work toward lowering your calories.

• Avo Avoid id high high calor calorie ie foods foods • Avo Avoid id eating eating late at night night • Stop eating once you are satisfied (leaving extra food on the plate) • Don’t eat while you are distracted (as when watching watc hing TV) • Try short-term fasting (for about two days at a time) You can foll follow ow a mod modifie ified d version version of calor caloric ic restric restriction tion with short-term fasts. For many, this is more realistic than long-term reduction of calories. Fasting triggers increased production of human growth hormone, one of the most important anti-aging hormones. Fast for one or two days at least once a month. Begin by fasting for one day this week. Drink lots of water while you fast.

Workk the lar large ge muscl musclee groups groups firs firstt (think (think legs and back back)) 4 Wor 4 Perform strength training exercises only 3 times a week 4 Perform the exercises at high intensity for short duration

27


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•


28

4 Progressively increase your work load to stimulate

— WEEK 2 ————————————————

Apply stress-reducing techniques: Your body produces the hormone cortisol under stress. In larger amounts, cortisol is destructive. Cortisol kills brain cells.

You can lowe lowerr cortis cortisol ol by by reducin reducingg stress. stress. Appl Applyy these these simple simple techniques to lower your stress: Breathing techniques: Breathing techniques can help to calm yourr body. you body. Dr. Dr. Andrew Andrew Weil has som somee very very good good breat breathing hing inst instruc ruc-tion tapes. You can learn more by visiting his website at www.DrWeil. com. Let it out: Write down worries or talk about them with a friend, family member, or therapist. Do your favorite thing: Make time to do an activity that relaxes you, such as a hobby, and forget about your worries. Meditate: Meditation can be very simple. It is a time that you use to focu focuss within within yours yourself. elf. Tak Takee 10 or 15 15 minute minutess out out of you yourr day to do this.

— WEEK 3 ————————————————

Begin anti-aging exercise routine: You lose muscle as you age. The amo amount unt of of muscl musclee you you have have is key in the the regula regulation tion of aging. The best way to build youthful muscle is with the right kind of exercise.

muscle growth 4 Use slow and smooth movements to prevent injury

— WEEK 4 ————————————————

Begin to change your diet: Restricting calorie intake is a reliable way to extend life span. It works in every animal model. Caloric restriction slows the rate of cell division. Here are some strategies that will stop you from overeating and help you to work toward lowering your calories.

• Avo Avoid id high high calor calorie ie foods foods • Avo Avoid id eating eating late at night night • Stop eating once you are satisfied (leaving extra food on the plate) • Don’t eat while you are distracted (as when watching watc hing TV) • Try short-term fasting (for about two days at a time) You can foll follow ow a mod modifie ified d version version of calor caloric ic restric restriction tion with short-term fasts. For many, this is more realistic than long-term reduction of calories. Fasting triggers increased production of human growth hormone, one of the most important anti-aging hormones. Fast for one or two days at least once a month. Begin by fasting for one day this week. Drink lots of water while you fast.

Workk the lar large ge muscl musclee groups groups firs firstt (think (think legs and back back)) 4 Wor 4 Perform strength training exercises only 3 times a week 4 Perform the exercises at high intensity for short duration

27


•


— WEEK 5 ————————————————

Balance your sex hormones: Get your hormone levels checked by your doctor. This is as easy as a blood test. Make sure yourr doctor you doctor chec checks: ks:

• Testosterone • Estrogen • DHEA Once you know your hormone levels, make a plan with your doctor to correct any imbalances. Men who need to boost their testosterone can use: DHEA: You make all of your sex hormones from DHEA, taking a DHEA supplement is often a good place to start. DHEA will also help to lower your levels of cortisol. Androstenedione: The athletes call androstenedione “andro”. Like DHEA, it is available over-the-counter at nutrition stores. Andro is the immediate precursor to testosterone.

Women Wom en can can natura naturally lly bal balance ance horm hormones ones::


•


28

They can take the edge off irritating and frustrating menopausal symptoms.

— WEEK 6 ————————————————

Regain Youthful Levels of HGH: HGH (human growth hormone) is the most powerful weapon in an anti-aging physician’s arsenal. Your body produces high amounts of HGH as a child but the production declines throughout your adult life. This orchestrated decline causes and controls many of the changes of aging. Get your levels of HGH checked by your doctor. If it is low, take the following action: Eat more protein: When you eat high amounts of protein, your HGH levels rise. Perform strenuous exercises: Strenuous exercise increases levels of HGH in your body. It must be heavy exercises like squats, leg presses and dead lifts.

Remember for any resolution to work you must follow through. You can do better better than mos mostt just just by getti getting ng starte started. d. Begin Begin with with step step one today.

Dong Quai: It contains phytoestrogens that occupy estrogen receptor sites in your body. It is very effective for gentle treatment of menopausal symptoms like hot flashes. 500 mg in tablet form, twice a day. Black Cohosh: It also contains phytoestrogens. I use it to ease menopausal depression and hot flashes. 250 mg in tablet form, three times a day.

Both of these supplements are available in natural food stores.

29


•



•


30

— WEEK 5 ————————————————

Balance your sex hormones: Get your hormone levels checked by your doctor. This is as easy as a blood test. Make sure yourr doctor you doctor chec checks: ks:

• Testosterone • Estrogen • DHEA Once you know your hormone levels, make a plan with your doctor to correct any imbalances. Men who need to boost their testosterone can use: DHEA: You make all of your sex hormones from DHEA, taking a DHEA supplement is often a good place to start. DHEA will also help to lower your levels of cortisol. Androstenedione: The athletes call androstenedione “andro”. Like DHEA, it is available over-the-counter at nutrition stores. Andro is the immediate precursor to testosterone.

Women Wom en can can natura naturally lly bal balance ance horm hormones ones::

They can take the edge off irritating and frustrating menopausal symptoms.

— WEEK 6 ————————————————

Regain Youthful Levels of HGH: HGH (human growth hormone) is the most powerful weapon in an anti-aging physician’s arsenal. Your body produces high amounts of HGH as a child but the production declines throughout your adult life. This orchestrated decline causes and controls many of the changes of aging. Get your levels of HGH checked by your doctor. If it is low, take the following action: Eat more protein: When you eat high amounts of protein, your HGH levels rise. Perform strenuous exercises: Strenuous exercise increases levels of HGH in your body. It must be heavy exercises like squats, leg presses and dead lifts.

Remember for any resolution to work you must follow through. You can do better better than mos mostt just just by getti getting ng starte started. d. Begin Begin with with step step one today.

Dong Quai: It contains phytoestrogens that occupy estrogen receptor sites in your body. It is very effective for gentle treatment of menopausal symptoms like hot flashes. 500 mg in tablet form, twice a day. Black Cohosh: It also contains phytoestrogens. I use it to ease menopausal depression and hot flashes. 250 mg in tablet form, three times a day.

Both of these supplements are available in natural food stores.


29

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Fossel M “Telomerase and the aging cell: implications for human health” Journal health” Journal of the American Medical Association June Association June 3, 1998, pp. 1732-5 i

Xu et al. “Homocysteine accelerates endothelial cell senescence,” senes cence,” FEBS Letters 2000, vol 470, pp. 20-24. ii

Zglinicki T, “Telomeres influencing the rate of aging.” Annals aging.” Annals of the New York Nov 20, 1998, vol 854, pp. 318-27. Academy of Science Nov iii

Morales CP, et al. “Absence of cancer-associated changes in human fibroblasts immortalized with telomerase.” Nature Genetics 1999; Genetics 1999; vol. 21, pp. 111-118. iv

Furumoto K. et al. “Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress.” Life Science 1998, vol. 63, no. 11 pp. 935-48.

v

Fozard J, et al., Epidemiologists try many ways to show that physical activity is good for seniors health and longevity: review of special issue of the Journal of Aging and Physical Activity: The Evergreen Project. Exp Aging Res 1999; 25: 175-182

vi

Klatz R. Hormones of Youth American Academy of Anti-Aging, Chicago 1999 p. 47-48

vii

viii

ix

Klatz, Hormones of Youth, Chicago 1999 p. 93 p. 93

Ibid. p. 93

Adapted from Regelson W and Colman C, The Super-Hormone Promise, Pocket Books: New York 1996 x

30

Fossel M “Telomerase and the aging cell: implications for human health” Journal health” Journal of the American Medical Association June Association June 3, 1998, pp. 1732-5 i

Xu et al. “Homocysteine accelerates endothelial cell senescence,” senes cence,” FEBS Letters 2000, vol 470, pp. 20-24. ii

Zglinicki T, “Telomeres influencing the rate of aging.” Annals aging.” Annals of the New York Nov 20, 1998, vol 854, pp. 318-27. Academy of Science Nov iii

Morales CP, et al. “Absence of cancer-associated changes in human fibroblasts immortalized with telomerase.” Nature Genetics 1999; Genetics 1999; vol. 21, pp. 111-118. iv

Furumoto K. et al. “Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress.” Life Science 1998, vol. 63, no. 11 pp. 935-48.

v

Fozard J, et al., Epidemiologists try many ways to show that physical activity is good for seniors health and longevity: review of special issue of the Journal of Aging and Physical Activity: The Evergreen Project. Exp Aging Res 1999; 25: 175-182

vi

Klatz R. Hormones of Youth American Academy of Anti-Aging, Chicago 1999 p. 47-48

vii

viii

ix

Klatz, Hormones of Youth, Chicago 1999 p. 93 p. 93

Ibid. p. 93

Adapted from Regelson W and Colman C, The Super-Hormone Promise, Pocket Books: New York 1996 x

Wright J. Maximize Your Vitality and Potency, Smart Publications, CA: 1999 199 9

xi

Muscle and Fitness, 1996 Sept; 140: 224

xii

Wright, J and Morgenthaler J. Natural Hormone Replacement Smart Publications CA: 1997

xiii

xiv

xv

Reiss U. Natural Hormone Balance for Women Pocket Books NY: 2001

Klatz, R. Grow Young with HGH Harper Collins, NY: 1997

Gibney J. et al., The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients J Clin Endrocrinol Metab 1999 Aug; 84(8): 25962602

xvi

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www.VitalMaxVitamins.com www.VitalMaxVitamins.c om

Six Weeks Anti-aging program

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