flujo (mL/min)
Eq.
t (min) 0,25
75
0,5
0,75
1
31,25 31,25 31,25 31,25 3 0,9765 7,8125 15,625 31,25
4
1,5 1,5
5
7
31,25
62,5
62,5
62,5
31,25
62,5
62,5
62,5
62,5
62,5
62,5
10 62,5
31,25
39,063 19,531
31,25
31,25
17,578
16,6
15,625
31,25
31,25 78,125
62,5
62,5
62,5
31,25
7,8125 3,9063 1,9531
2
7,8125
15,625
31,25
31,25
31,25 31,25 15,62
15,62
7,8125
1,952
6
31,25
31,25
62,5
62,5
62,5
5
15,625
31,25
31,25
3 1,25
31,25
31,25 31,25
31,25 54,688 46,87 46,88 39,06
10
15
20
46,875 39,063 19,531 17,578
5
46,87 46,87 39,06
5
7
10
15
20
25
10
15
20
25
31,25 23,437 11,719 11,719 4,8828 2,4414 0,9765
4,3945
0,9765
0,4883
0,488
0,4883
0,4883
0,4883
11,719 4,8828
30
35
2,4414 0,9765
B
r
50,4299
-1,4131
-0,9375
30
35
44,0103
-1,572
-0,9007
26,1667
-0,9058
-0,847
39,06 19,531 4,8823 2,4381 1,2205 0,73225 0,4883 0,4883
7
8,30075
31,25 31,25 31,25 15,625 7,8125 1,9531 0,9765 0,9765
16,6 8,30075 4,3945
25
7,8125
0,4883
31,25 46,875 46,87 46,875 46,88 46,88 31,25 23,437
7
0,9765
15,625
0,9765
31,25
2,4381 1,2205
0,9765
0,9765
31,25 31,25
19,531 4,8823
0,488
35
0,73225
62,5
39,06
0,97
30
15,625 7,8125 3,9063 0,9765
62,5
A
3
25
7,8125
Promedio
2
20
15,625 7,8125 3,9063 1,9531
62,5 46,875
62,5
15
1
Promedio 175
3
31,25
Promedio 125
2
30
35
0,7324 0,7324 0,7324
0,7324 0,7324
A,B Y r DE ELIMINACION
Flujo 75 mL/min
A=50,4299
A=44,0103
A=26,1667
B=-1,4131
B=-1,572
B=-0,9058
r=-0,9375
r=-0,9007
r=-0,847
Flujo 125 mL/min ABSORCION A= 4.3833 B= -1.0554 r= -0.9486 ELIMINACION A=44,0103 B=-1,572 r=-0,9007
A= 4.2666 B= -0.3656 r= -0.9682 A=50,4299 B=-1,4131 r=-0,9375
Flujo 175 mL/min A= 3.8030 B= -1.5232 r= -1 A=26,1667 B=-0,9058 r=-0,847
Formula para el calculo del área bajo la curva
ABC0- = ∞
=1
−
Cp2+Cp1 (t2 t1 2
+
Cpúltima ke
masa.tiempo/volumen (mg.min/mL)
