Faktor-faktor Yang Mempengaruhi Stabilitas Suspensi

TUGAS FARMASETIKA II FAKTOR-FAKTOR YANG MEMPENGARUHI STABILITAS SUSPENSI

Disusun Oleh : Kelomo! " T#i Bu$i H%s&u&i

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BAB I PENDAHULUAN

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.8 Sus Susen ensi si To Toi!% i!%ll

A$%l%h se$i%n >%i# 1%n, men,%n$un, %#&i!el %$%& $%l%m 9en&u! h%lus 1%n &e#$ise#si $%l%m em9%3% >%i# 1%n, $i&unu!%n un&u! en,,un%%n  %$% !uli&8 )8 Sus Susen ensi si &e&e &e&ess &eli &elin, n,%% A$%l%h se$i%n >%i# m%n,%n$un, %#&i!el-%#&i!el h%lus u%n, $i&unu!%n un&u! $i&e&esi %$% &elin,% 9%,i%n lu%#8 "8 Sus Susen ensi si o0& o0&%l %l%m %mi!  i!  A$%l%h A$%l%h se$i%n se$i%n >%i# >%i# s&e#il s&e#il 1%n, 1%n, men0%un men0%un, , %#&i! %#&i!el- el-%#& %#&i!e i!ell s%n,%& s%n,%& h%lus h%lus 1%n, &e#$ie#si $%l%m >%i#n em9%3% un&u! em%!%i%n %$% m%&%8 28 Sus Susen ensi si un&u un&u! ! in ine! e!si si A$%l%h se$i%n >%i# s&e#il 9e#u% susensi se9u! $%l%m me$ium >%i# 1%n, sesu%i $%n &i$%! 9oleh men1m9%& %#um sun&i!u% ;s1i#in,e %9ili&1= se#&% &i$%! $isun&i!!%n se>%#% in&#%en% %&%u !e $%l%m l%#i&%n sin%l8 /8 Susen Susensi si un&u! un&u! ine ine!si !si &e#! &e#!ons ons&i& &i&usi usi A$%l%h se$i%n %$%& !e#in, $en,%n 9%h%n em9%3% 1%n, sesu%i un&u!  mem9en&u! l%#u&%n 1%n, memenuhi semu% e#su1%#%&%n un&u! susensi s&e#il se&el%h en%m9%h%n 9%h%n em9%3% 1%n, sesu%i8 Dise#si !oloi$ $i>i#i!%n s%l%h s%&un1% $en,%n u!u#%n %#&i!el 1%n, &e#l%lu !e>il un&u! $ilih%& $en%n mi!#os!o 9i%s% se$%n, %#&i!el emulsi %&%u susensi 0%#m%si se#% se9u! h%lus 9e#%$% o%$% %n,!%u%n mi!#os!o o&i!8 Se$%n,!%n un&u un&u! ! sus susen ensi si sen$ sen$i# i#ii u!u# u!u#%n %n %#& %#&i! i!el el n1% n1% 9e#% 9e#%$% $% %n&% %n&%## %n,! %n,!%% (2 (2 C '( mi!#ome&e# ;M%#&in Al0#e$ $!! '<<)=8 Se$%n,!%n %$% sisi l%in Kee0e!&i0%n $%l%m $%l% m en,,un%!%n o9%& me#u%!%n s%l%h 0%!&o# en&in, $%l%m men>%%i e0e! &e#%eu&i! hin,,% mem9e#i!%n e0e!  1%n, o&im%l8 E0e!&i0i&%s o9%& s%l%h s%&un1% $%%& $ilih%& $%#i !es&%9il%n o9%& &e#se9u &e#se9u&8 &8 P%$%h% P%$%h%ll s%l%h s%l%h s%&u m%s%l% m%s%l%h h 1%n, 1%n, $ih%$% $ih%$%i i $%l%m $%l%m #oses #oses em9u% em9u%&%n &%n hin, hin,,% ,%

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Oleh Oleh !%#en% !%#en% i&ul%h i&ul%h %$% %$% m%!%l%h m%!%l%h ini ini enuli enuliss %!%n %!%n mem9%h mem9%h%s %s &e#!%i& &e#!%i& 0%!&o#-0%!&o# 1%n, %!%n memen,%#uhi !es&%9il%n $%l%m se$i%n susensi ini8

BAB II PEMBAHASAN

'8 Pen, Pen,e#& e#&i% i%n n Sus Susen ensi si Susensi %$%l%h se$i%%n 1%n, men,%n$un, 9%h%n o9%& $%l%m 9en&u! h%lus 1%n, &i$%! l%#u& &e&%i &e#$ise#si $%l%m >%i#%n8 %& 1%n, &e#$ise#si h%#us h%lus $%n &i$%! 9oleh >e%& men,en$% men,en$% i!% $i!o>o! $i!o>o! e#l%h%n-l%h% e#l%h%n-l%h%n n en$%%n en$%%n h%#is se,e#% &e#$ise#si !em9%li8 Susensi umumn1% men,%n$un, %& &%m9%h%n un&u!  men%min men%min s&%9ili&%sn1 s&%9ili&%sn1% % se9%,%i s&%9ilis%&o# s&%9ilis%&o# $%%& $ie#,un% $ie#,un%!%n !%n 9%h%n-9%h% 9%h%n-9%h%n n $ise9u& se9%,%i emul,%&o# ;oenoes '<<(=8 Susen Susensi si u,% u,% $%%& $%%& $i$e0en $i$e0enisi! isi!%n %n se9%,% se9%,%ii #e%# #e%#%& %& 1%n, 1%n, men,%n men,%n$un $un, ,  %#&i!el o9%& 1%n, &e#9%,i se%#% h%lus ;$i!en%l se9%,%i susensoi$= $ise9%#!%n se>%#% me#%&% $%l%m em9%3% $im%n% o9%& menunu!%n !el%#u&%n 1%n, s%n,%& minimum8 Be9e#%% susensi #esmi $ie#$%,%n,!%n &e#se$i $%l%m 9en&u! si%  %!%i &el%h $ise9%#!%n $%l%m >%i#%n em9%3% $en,%n %&%u &%n% ens&%9il $%n  9%h%n &%m9%h%n 0%#m%se&i! l%inn1% ;Ansel '<*<=8 .8 F%!&o# F%!&o# - F%!&o# F%!&o# 1%n, 1%n, Memen,% Memen,%#uhi #uhi S&%9ili&%s S&%9ili&%s Susen Susensi si S%l%h S%l%h s%&u m%s%l%h m%s%l%h 1%n, 1%n, $ih%$% $ih%$%i i $%l%m $%l%m #oses #oses em9u% em9u%&%n &%n susen susensi si %$%l%h %$%l%h >%#% >%#% meme#l meme#l%m9 %m9%& %& enim9 enim9un% un%n n %#&i! %#&i!el el se#&% se#&% men%, men%,%% homo,e homo,eni& ni&%s %s  %#&i!el8 %#% &e#se9u& me#u%!%n s%l%h s%&u &in$%!%n un&u! men%,% s&%9ili&%s susensi8 Be9e#%% 0%!&o# 1%n, memen,%#uhi memen,%#uhi s&%9ili&%s susensi %$%l%h : %8 U!u U!u#%n #%n %# %#&i &i!e !ell U!u#%n %#&i!el e#%& hu9un,%nn1% $en,%n lu%s en%m%n, %#&i!el &e#se9u& se#&% $%1% &e!%n !e%&%s $%#i >%i#%n susensi i&u8 Hu9un,%n %n&%#% u!u#% !u#%n n

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>8 5uml 5uml%h %h %#& %#&i! i!el el ;!on ;!onsen sen&#% &#%si= si= A%9il% $i$%l%m su%&u #u%n,%n 9e#isi %#&i!el $%l%m uml%h 9es%# m%!% %#&i!el &e#se9u& %!%n sus%h mel%!u!%n ,e#%!!%n 1%n, 9e9%s !%#en% se#in se#in, , &e#%$ &e#%$ii 9en& 9en&u# u#%n %n %n&% %n&%#% #% %#& %#&i! i!el el &e#se &e#se9u 9u&8 &8 Ben& Ben&u# u#%n %n i&u i&u %!%n %!%n men1e9 men1e9%9! %9!%n %n &e#9en& &e#9en&u!n u!n1% 1% en$%% en$%%n n $%#i $%#i %& &e#se9u &e#se9u& & oleh oleh !%#en% !%#en% i&u m%!in 9es%# !onsen&#%si %#&i!el m%!in 9es%# &e#%$in1% en$%%n %#&i!el $%l%m 3%!&u 1%n, sin,!%& ;S1%msuni .((4=8

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