DRUG STUDY Medical Diagnosis: hydrocephalus, status post- shunt insertion Category:
Generic Name: furosemide Brand Name: Lasix Classification: Diuretics Dosage: 5mg(0.5ml)
Indication/ Contraindication INDICATIONS : Edema due due to cardi cardiac ac,, hepatic & renal disease, burns; burns; mild to moderate HTN HTN, hyperte ertens nsiv ivee crisis, acute heart failure, failure, reduced reduced urinary urinary output output due to gestoses, chronic renal renal failure failure,, nephrotic syndrome. syndrome .
: CONTRADICTIONS
Anuria; hepatic coma & Frequency: precoma; severe Every 12 hours. Hold for hypokalemia &/or BP less than 85 systolic hyponatremia; hypovolemia w/ or w/o Route: hypotension. IV Push Hypersensitivity Hypersensitivity to sulfonamides.
Mechanism of Action
Inhibit Inhibit reabsorp reabsorption tion of sodium and water in the ascen ascendin ding g limb limb of the loop of Henle by inte interf rfer erin ing g with with the the chloride binding site of the the 1Na 1Na+, 1K+, 1K+, 2Cl2Clcotr cotran ansp spor ortt syst system em.. Loop Loop diuretic diureticss increase increase the the rate rate of delive delivery ry of tubular fluid and electrolytes to the distal sites sites of hydrog hydrogen en and and potassium ion secretion, whil whilee plas plasma ma volu volume me contr contrac actio tion n increa increases ses aldosterone aldosterone production. production. The increase increased d delivery delivery and and high high aldo aldost ster eron onee levels levels promote promote sodium sodium reabsorption at the distal tubules, tubules, thus increasi increasing ng the the loss loss of pota potass ssiu ium m and hydrogen ions.
Side Effects/ Adverse Effects • low blood pressure, pressure, • dehydration and electrolyte depletion (for example, sodium, potassium). • jaundice, jaundice , • ringing in the ears (tinnitus (tinnitus), ), • sensitivity to light (photophobia), • rash, • pancreatitis, pancreatitis, • nausea, nausea , • diarrhea, diarrhea , abdominal • pain, and dizziness. dizziness . Increased blood sugar and uric acid levels
Nursing Considerations •
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Assess patient’s nderlying condition before starting theraphy. Monitor for renal cardiac,neurologic, cardiac,neurologic, GI manifestations manifestations of hypokalemia. Monitor for CNS, GI, cardiovascular, integumentarym neurologic manifestations of jypocalcemia, Monitor for CNS, hyperactive reflexes, depressed cardiac output,nausea, vomiting, tachycardia Assess fluid volume status(urine,color, status(urine,color, quality and specific gravity) Assess patient tinnitus, or pain