Determinación de Bilirrubina DirectaDescripción completa
Tema: BILIRRUBINA ALUMNA ALUM NA:: CHI CHIP PANA ANA ORDOÑO, ORDOÑO, NILDA
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DEFINICION
C 33 H 36 O6 N4
La bilirrubina es un pigmento biliar de color amarillo anaranjado que resulta de la
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ORIGEN DE LA BILIRRUBINA
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METABOLISMO DE LA BILIRRUBINA
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TRANSPORTE, CONJUGACIÓN, EXCRECIÓN
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DOSAJE DE BILIRRUBINA EN SANGRE Se realiza en el contexto de otras pruebas hepáticas.
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se utiliza para evaluar problemas o alteraciones del
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hígado y vías biliares. En los pacientes con ictericia se mide la bilirrubina
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total la directa y la indirecta. Cuando la fracción conjugada o directa:
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más de un 50% de la bilirrubina total, es que que hay
un problema en la vía biliar por cálculos, inflamación o
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MEDICAMENTOS QUE ALTERAN EL NIVEL DE BILIRRUBINA: Esteroides Antibióticos
• •
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VALORES NORMA NORMALES: LES: Bilirrubina directa (conjugada): hasta 0.2 mg/% ó mg/ml
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HIPERBILIRRUBINEMIA Cuando la cifra de Bilirrubina en la sangre excede de 1mg/dl 1mg/dl
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ICTERICIA PRE HEPÁTICA O HEMOLÍTICA Existe demasiada bilirrubina en sangre para poder ser eliminada.
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ICTERICIA HEPÁTICA O HEPATOCELULAR Se debe al fallo para excretar la Bilirrubina desde el hepatocito al duodeno. Daño del hepatocito que lo hace insuficiente en sus funciones • Defectos de conjugación y •
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Ictericia post hepática u obstructiv obstructivaa
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UROBILINA EN ORINA
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