A Manual of Empathogenic Empathogenic Etiquette and Safety By 5HT2Infinity
MDMA is not simply recreational, it is medicinal. It can heal trauma, uplift self-esteem, heighten empathy, deepen relationships and improve outlook on life. As with any substance, there are risks involved. If used improperly, improperly, MDMA’s emotional panacea quickly descends into a into a neurotoxic nightmare. Nonetheless, it is a powerful psychopolitic technology. Here are some basic principles that must be followed if you are to safely employ its full empathogenic capacity. Purity First, you must verify that your material is in fact MDMA, for the black market is a platform for dangerous deception. When introduced into popular culture in in the 90’s, 90’s, MDMA acquired the nickname ‘Ecstasy’. ‘Ecstasy’. In order to facilitate distribution, it was pressed into pills. The purity of the Ecstasy pills quickly came into question as adulterants were added to increase profits, since MDMA synthesis precursors are rare and expensive. The adulterants range from Caffeine to Methamphetamine, PMA and PMMA. The latter ones easily cause fatal serotonin syndrome. The recreational drug community has now coined the term ‘Molly’ to designate pure MDMA powder or crystals in order to distinguish it from impure pills. However, vendors insidiously sell adulterated powder and crystals as ‘Molly’. Today, most ‘Molly’ is a mixture of Methylone and Amphetamines. Methylone Methylone is a slightly less less potent analog analog of MDMA. Whereas Whereas MDMA typically typically requires between 90 – 120mg (~ 1 point) to produce full effects, Methylone requires 170 - 200mg (2 points). In order to compensate f or or Methylone’s relative lack of strength, vendors add vendors add Amphetamines. This combination is highly highly toxic, resulting resulting in 3-4h of uncomfortably uncomfortably stimulating stimulating euphoria followed by a harsh comedown. Thus, for your safety, it is crucial to distinguish MDMA from adulterated ‘Molly’. This ‘Molly’. This can be done with a Marquis reagent, which is easily obtained online. MDMA turns black in a Marquis reagent, whereas Methylone turns yellow. However, MDA (a psychedelic and stimulating MDMA analog) cannot be distinguished from MDMA with this test because it also turns black. For certainty, Simon’s reagent can be used. It turns blue with MDMA and has no reaction with MDA. Know your source! Know your supply! Pharmacology MDMA releases Serotonin, Dopamine and Norepinephrine in decreasing order of magnitude. It attaches to the reuptake transporters responsible for remo ving these neurotransmitters from the synapse, forcing them to instead pump more neurotransmitters into the synapse. This leads to massive increase in empathy (Serotonin), motivation (Dopamine) and wakefulness (Norepinephrine). MDMA also indirectly releases Oxytocin, known colloquially as the ‘love hormone’. Oxytocin is notable for its ability to induce to induce deep emotional connections. It also increases neuroplasticity. In other words, Oxytocin rewires neural circuits, catalyzing positive emotional transformations. However, if used too frequently or in excessive doses, MDMA induces depression and anxiety. This occurs for a variety of reasons: First, excessive use depletes the brain’s reserves of reserves of Serotonin. Second, it induces oxidative damage, causing neurotoxicity. Third, it may increase the expression of the enzyme Monoamine Oxidase (MAO), which is responsible for destroying Serotonin, Dopamine and Norepinephrine. This results in long lasting fatigue, emotional exhaustion and dullness.
Dosage and Frequency of Use MDMA is usually taken in doses of 90 – 125mg, although larger persons or users with tolerance may take up to 200mg to achieve full effects. Dosing has a sweet spot – excessive doses are confusing and unpleasant due to side effects such as jaw clenching, nistagmus (uncontrollable (uncontrollable eye wiggles), urinary retention retention (the cause cause of water poisoning poisoning or hyponatremia), hyponatremia), short term memory memory loss, hypertension (increased blood pressure) and tachycardia (increased heart rate). Therefore it is best to slowly work your way up to your personal sweet spot. Always keep in mind that MDMA gives diminishing returns. This occurs due to Serotonin depletion and desensitization of Serotonin receptors, sometimes producing a permanent tolerance colloquially colloquially referred to as a ‘loss of magic’. The more you use MDMA, the less magic magic you get. Thus, for sake of health and maintenance of positive effects, it should only be used occasionally. You may successfully take MDMA once a year for decades. If used every three months, you may retain the magic for many years. If used monthly, monthly, the magic will subside within 6 months or so. If If used weekly, the magic subsides within weeks, inducing depression. If used twice in one week, the second administration will not produce produce significant effects, effects, because Serotonin Serotonin reserves takes more than a week week to replenish. It is very unreasonable unreasonable to take MDMA more than once within such a short time frame, for you will almost surely experience a crash - intense depression arising 1-2 days after the experience (hence the term ‘suicide Tuesdays’ among frequent MDMA users). users). Administration Methods Methods -
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Oral administration is the most common method, since it produces maximum lasting effects of 4-6 hours. The onset is typically between 30min and 1 hour. Oral administration requires an empty stomach (~3h without food), lest you dilute the effects to the point of dampening the experience. This is the recommended, safe administration method. Nasal administration (insufflation, snorting) leads to a quick onset of 5 – 30 minutes, a more intense peak effect and shorter total duration of approximately 2-3 hours. This route can be very dangerous, since it facilitate overdoses. Avoid.
There can be a strong urge to redose once the effects begin to fade. Generally, redosing after the 2nd hour fails to extend the duration. If you wish to extend the duration by about 1 hour, 25% of the full dose should be taken 1 hour and 30min after the initial ingestion. This will, however, increase the manifestation of side effects. Contraindications and Interactions SSRI’s and Tricyclic Antidepressants: these substances block substances block the effects of MDMA. They outcompete MDMA for the Serotonin transporter, blocking Serotonin release. If you are taking these substances, the only way to successfully administer MDMA is to stop taking them for as long as is necessary for them to exit your bloodstream. If you have been taking SSRI’s for a long time, your Serotonin receptors are already significantly desensitized, resulting in tolerance. It is risky to stop taking SSRI’s for the purpose of taking MDMA . On the other hand, MDMA may provide you with deep deep emotional insight far beyond anything that SSRI’s have to offer. Whereas
SSRI’s mildly muffles sadness, MDMA gives you the power to honestly encounter your most problematic emotions with positivity, so that you may come to terms with them and eventually surpass them. This is why MDMA is the only effective cure for Post-Traumatic Stress Disorder (PTSD). Benzodiazepines: Decrease the stimulating effects of MDMA. Used to counteract overdoses. Antipsychotics: Block Block the effects of MDMA. Pharmaceutical MAOI’s: Danger! MAOI’s: Danger! This interaction causes fatal serotonin syndrome. Amphetamines: Danger! Danger! This interaction interaction will significantly significantly increase increase the side effects of MDMA, and facilitates overdoses. Alcohol: Danger! This interaction will significantly significantly increase the side side effects of MDMA, as well as blunt the positive effects. Cocaine: Blocks the effects of MDMA (outcompetes MDMA for the Serotonin transporter). Cannabis: This interaction is generally quite favorable, for Cannabis is an antioxidant and protects against MDMA’s side effects, side effects, as well as amplifying the positive effects. However, Cannabis and MDMA combined result in significant tachycardia. Viagra: Danger! Results in extreme extreme tachycardia. Mood stabilizers: Danger! Unpredictable interactions. Discontinue any mood stabilizers a couple of days before taking MDMA. Supplementation In order to maximize the positive effects and minimize the negative ones, it is crucial to take a variety of supplements supplements before, during during and after the the experience. All these can can be found online. Antioxidants: -
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Multivitamin: you must take this every day on a full stomach if you take psychoactive substances. Vitamin C: take one gram one hour before taking taking the MDMA, MDMA, one gram during during the experience and one gram after the effects e ffects subside. Green Tea: excellent source of antioxidants. Drink some before and during the experience Curcumin Extract and Resveratrol: these powerful antioxidants should be taken with the meal preceding the experience. They will increase the euphoric effects. Acetyl-L-Carnitine, Alpha Alpha Lipoic Acid and and Ubiquinol: these are the ultimate antioxidants. They ensure you do not permanently damage your nervous system, even in relatively extreme conditions. Take with the meal preceding the experience. Melatonin: 5mg will help you sleep restfully after the experience.
Neurotransmitter Support -
Magnesium: This is essential to avoid jaw clenching. Take 200mg of the Glycinate form 1 hour before the experience. - 5-HTP: This is the precursor to Serotonin. It will help replenish your Serotonin levels after the experience. Take 100mg after drinking some Green Tea, which will aid its absorption. Avoid taking 5-HTP before the experience, for it may may result in serotonin serotonin syndrome. Also avoid taking 5-HTP regularly because it may desensitize your receptors over long periods of time. - L-Dopa: This is the precursor to Dopamine. It will replenish your Dopamine levels after the experience. Take 100mg the day after the experience to decrease fatigue. - SAMe: This will speed up the natural production of neurotransmitters. Take 400mg in the morning on an empty stomach for about one week after the experience. Hydration, Food You must be appropriately fed and hydrated during the the day of the experience. experience. Make sure you drink at least 5-7 glasses of water throughout the day. Do not drink more than 12 glasses, since this may cause hyponatremia (water poisoning due to imbalanced electrolytes). Also make sure you have consumed consumed at least 1500 kcal of protein and carbohydrate. carbohydrate. Avoid fatty foods for they may interfere with MDMA absorption. Sleep If you plan on taking any sort of psychoactive, it is especially important that you are well rested. r ested. This ensures a positive experience. Do not take MDMA if you are sleep deprived, lest you be unable to properly recall the experience. Sleep deprivation also lowers levels of antioxidants in your body, leading to to increased damage damage and lasting side effects. It is also very important to get at least 9 hours of sleep after the experience, so your body has time to recover. Setting MDMA is enormously popular due to its unique ability a bility to enhance dancing, and is therefore stereotypically portrayed as a rave drug. This is merely a recreational approach. Psychiatrists have advocated that it be taken in a calm environment, favoring communication and intimacy. Communicating your feelings is the crux of the healing properties of MDMA, so be among those who can acknowledge acknowledge your feelings feelings and talk about about them openly. openly. Strangers or merely acquaintances usually won’t resonate deeply with your feelings, nor provide you with the feedback that is necessary for the consolidation of long lasting positive resolutions, especially if they are not on MDMA. MDMA is 3,4-Methylenedioxide-N-Methylamphetamine. 3,4-Methylenedioxide-N-Methylamphetamine. What it brings is ecstasy. What it teaches is empathy. The learning depends on you. Happy rolling! -
5HT2Infinity
