Pharmaceutical Chemistry

WHAT WHA T IS ALUMINUM? ALUMINUM?  

Aluminum is discovered by Hans Oersted at Copenhagen, Denmark in 1825

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!he name is derived "rom the #atin name "or Alum, $Alumen% meaning bitter salt

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&ain group 1' ()))A, or boron group* o" the periodic table

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!hird most abundant element in the earth+s crust (81*

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)n its purest "orm the metal is silvery-.hite, silvery-.hite, light.eight metal and very ductile

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/0cellent conductor o" heat and electricity

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!henards blue test

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Abrasive in industries

O34C/  

Cryolite -(odium he0a"luoroaluminate, 6a₃Al7 ₆*

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Chie" source au0ite ore

PHARMACEUTICAL USES:  

Deodorant

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Analgesics

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9rotectant

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Antidiarrheal

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Antiseptic

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Astringents

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Antiperspirant

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Ad:uvants "or

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Antacids

vaccines

PHARMACOLOGICAL ACTIONS: Aluminum 7oil 

!reatment o" burns

 Adverse /""ects 

 Constipation

!o0icity 

havers disease

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ayer process- essentially re"erring to the re"ining o" bau0ite, the most important aluminum ore, to produce alumina

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Hall-Heroult process- intermediate alumina must be smelted into metallic aluminum

Name of Compounds Aluminum acetate

Common name/s

Fomu!a

uro.s solution Domeboros solution

Al(C2H'O2*'

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Al2(CO'*'

•

• •

Aluminum carbonate

Uses

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Aluminum chloride

AlCl'

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Aluminum hydro0ide

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Ampho:el Cremalin gel

Al(OH* '

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Astringent

treatment o" hypophosphate mia in renal insu""iciency prevent phosphate urinary calculi Astringent Antiseptic

used as an antacid and phosphate binder

Name of Compounds

Common name/s

Aluminum chlorohydrate Aluminum o0ide

Fomu!a Al2(OH*5Cl;2H2O

Uses

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Alumina

Al2O'

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9hosphagel

Al9O<

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Aluminum subacetate

C
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Aluminum sul"ate

Al2(O<*'

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Aluminum phosphate

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deodorant antiperspirant !reatment o" silicosis

used as a gastric antacid, astringent, and soothing agent

astringent used as an astringent solution antiperspirant

Aluminum ilicate (Al2iO5*   >aolin $native hydrated aluminum silicate%  $china clay%  adsorbent and demulcent in diarrhea 

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entonite $native hydrated colloidal aluminum silicates  mineral soap, soap clay  suspending agent 

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9umice $sodium potassium aluminum silicates%  volcanic origin  dental abrasive, denti"rice 

4e"erences 

?arrison posito !he /nvironmental chemistry o" Aluminum pg5=-=2 December 1, 2@@8

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/nvironmental chemistry and !o0icology o" Chemistry December 2, 2@@8

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9etrucci, ?eneral Chemistry, 9rinciples  &odern Applications, by &acmillan 9ublishing Company, 6inth /dition, pg 8B1-8B'

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Aluminum !he Columbia /ncyclopedia th ed 6e. Eork Columbia 39, 2@@B

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Alumina !he Columbia /ncyclopedia th ed 6e. Eork Columbia 39, 2@@B