ANALGESICS/ANTI-PYRETICS DRUGS DOSE PARACETAMOL 10-20 mkdose q4 PO, IV Seizure: 15mkd
PREPARATIONS Drops: 60mg/0.6ml (TEMPRA) 100mg/ml (CALPOL) Syrup: 120mg/5ml AFEBRIN, CALPOL, TEMPRA 250mg/5ml AFEBRIN, CALPOL 6 PLUS, TEMPRA FORTE
IBUPROFEN
5-10mkdose q6-8 2-6 yrs: 5-10 ml 7-12 yrs: 10 ml
Syrup: 100mg/5ml (DOLAN FP)
MEFENAMIC ACID
6.5mkdose q6-8 PO
Syrup: 50mg/5ml Tab: 250mg, 500mg
AMINOPENICILLINS DRUGS DOSE AMOXICILLIN 30-50mkDay q8 PO
AMPICILLIN
50-100mkDay q6 PO Meningitic dose: 200400 mkDay q4-6 IV
CEPHALOSPORINS DRUGS
DOSE
PREPARATIONS Drops: 100mg/ml, 125mg/1.25ml Syrup: 125mg/5ml, 250mg/5ml (AMOXIL, GLAMOX, HIMOX, SUMOXIL) Syrup: 125mg/5ml, 250mg/5ml Cap: 250mg, 500mg Vial: 100, 125 500mg/vial (AMPICIN, AMPEDIA, PENSYN)
PREPARATIONS
1 GENERATION CEPHALEXIN
25-50mkDay q6 PO
Drops: 100mg/ml Syrup: 125mg/5ml, 250mg/5ml (KEFLEX, CEPOREX)
CEPHALOTHIN
80-160mkDay q6 IV
Vial: 1mg vial (KEFLIN)
20-40mkDay q12 PO 75-150mkDay q8 IV, IM
Susp: 125mg/5ml (ZINACEF, ZINNAT) 250mg/5ml (ZINNAT) 250mg, 750mg, 1.5mg/vial Tab: 125mg, 250mg, 500mg
CEFACLOR
40mkDay q8 PO
Susp: 125mg/5ml, (CECLOR)
CEFOXITIN
20-40mkDay q6-12 IV
Vial: 1g/vial (MEFOXIN)
50-100mkDay q12-24 IV Typhoid:75-80mkDay x7d
Vial: 250mg, (ROCEPHIN)
500mg,
1g/vial
CEFOTAXIME
100-200mkDay IV
Vial: 250mg, (CLAFORAN)
500mg,
1g/vial
CEFTAZIDIME
90-150mkDay q8 IV
CEFIXIME
1.5-3mkdose q12 PO
ST
2ND GENERATION CEFUROXIME
3 GENERATION CEFTRIAXONE
250mg/5ml
RD
q6-8
BETA LACTAMASE INHIBITORS DRUGS DOSE AMPICILLIN50-100mkDay q6 IV, SULBACTAM IM (based on Ampicillin) AMOXICILLINCLAVULANIC ACID or COAMOXICLAV
Vial: 250mg, 500mg, 1g/vial (FORTUM) Drops: 20mg/ml Susp: 100mg/5ml Cap: 100mg, 200mg (TERGECEF)
PREPARATIONS Vial: 375mg/vial (250mg Ampicillin) 750mg/vial (500mg Ampicillin)
30-50 mkDay q8 IV, PO (based on Amoxicillin)
Syrup: 156mg/5ml (125mg Amox) 312mg/5ml (250mg Amox) Cap: 375mg tab (250mg Amox) 625mg tab (500mg Amox) Vial: 300mg/vial (250mg Amox) 600mg/vial (500mg Amox) 1.2g/vial (1g Amox)
DOSE 50,000-100,000 UkDay q6 High dose: 150,000200,000 UkDay q6 PO
PREPARATIONS Susp: 125mg/5ml = 200,000 U/5ml 250mg/5ml = 400,000 U/5ml (PENTACILLIN, SUMAPEN)
50,000-100,000 UkDay q6 Meningitic dose: 200,000-400,000 UkDay q6 IV
Vial: 1,000,000 U/vial 5,000,000 U/vial
PENICILLINS DRUGS Penicillin V Phenoxymethylpenicillin
Aqueous Pen G Benzylpenicillin
PENICILLINASE RESISTANT PENICILLINS - skin infxn (10 days duration of tx) DRUGS DOSE PREPARATIONS CLOXACILLIN 75-100mkDay q6 PO Syrup: 125mg/5ml Tab: 250mg, 500mg tab OXACILLIN AMINOGLYCOSIDES
75-100 mkDay q6 IV
Vial: 250mg, 500mg/vial
DRUGS AMIKACIN GENTAMICIN TOBRAMYCIN NETILMICIN
DOSE 15-22.5 mkDay q8 IV, IM 5-8 mkDay q8 IV, IM
PREPARATIONS Vial: 100, 250, 500mg/2ml vial
6-7.5 mkDay q8 IV, IM 2.5 mkdose q8 IV, IM
Vial: 80mg/2ml vial (NEBCIN)
Vial: 80mg/2ml vial (GARAMYCIN)
Vial: 100mg/2ml vial (NETROMYCIN)
MACROLIDES DRUGS ERYTHROMYCIN
DOSE 30-50 mkDay q6 PO
PREPARATIONS ERYCIN, ERYTHROMYCIN: Drops: 100mg/2.5ml Syrup: 200mg/5ml (+ MACROCIN) ILOSONE: Drops: 100mg/ml Syrup: 125mg/5ml, 250mg/5ml ERY-MAX: Susp: 40mg,5ml Tab: 250mg, 500mg
CLARITHROMYCIN
7.5mkdose q12 PO
Susp: 125mg/5ml (KLARICID)
AZITHROMYCIN
10mkDay x3days PO
Susp: 200mg/5ml (ZITHROMAX)
COTRIMOXAZOLE *** don’t give for <6mos if w/G6PD due to risk of bleeding
5-8 mkDay q12 PO (based on TMP mg)
Syrup: 40mg/200mg/5ml (SEPTRIN, BACTRIM, TRIMOCON) Syrup: 80mg/400mg/5ml (SEPTRIN, TRIZOLE, BACTILLE TS) Susp: 45 mg/205mg/5ml (TRIGLOBE) Cap: 160mg/800mg, 80mg/400mg
CHLORAMPHENIC OL
50-100 mkDay q6 IV, PO
TMP mg/SMXmg/ml
ANTI-HISTAMINES DRUGS DOSE HYDROXYZINE 1-2 mkDay q12 PO
Syrup: 125mg/5ml Cap: 250mg, 500mg Vial: 1g/vial
PREPARATIONS Syrup: 2mg/ml Tab: 10mg, 25mg (ITERAX)
DIPHENHYDRAMI NE
5 mkDay q6 PO, IV Anaphylaxis: 1-2 mkdose IM, IV
Tab: 25mg Cap: 50 mg cap Vial: 50mg/ml (BENADRYL)
CETIRIZINE
2-6yrs: 5mg or 10gtts OD 6->12yrs: 1tab OD, 10mg or 20gtts OD
Oral drops: 10mg/ml Tab: 10 mg (VIRLIX, ZYRTEC)
CLEMASTINE
<1yr: 1-2.5ml BID 1-3yrs: ½ - 1tsp BID 6-12yrs: ½ - 1tab or 1 ½ tsp BID >12yrs: 1tab or 2tsp BID
Syrup: 0.5mg/5ml Tab: 1mg (TAVEGYL)
LORATIDINE
2-12yrs: <30kg: 1tsp OD >30kg: 2tsp OD >12yrs: 1tab OD
Syrup: 5mg/5ml Tab: 10mg (CLARITIN, ALLERTA)
CORTICOSTEROID DRUGS BETHAMETHASONE DEXCHLORPHENAMI NE MALEATE
ANTACIDS DRUGS Al(OH)3, Mg(OH)3, SIMETHICONE
AlMg(OH)3 (MAALOX) AlMg(OH)3, dimethicone (MAALOX PLUS)
DOSE 2-6yrs: 1/4tsp TID 6-12yrs: 1/2tab or ½tsp TID >12yrs: 1-2tab QID after meals
DOSE Pedia: 1tsp, taken 1hr & 3hrs after meals & HS Peptic ulcer: 2tabs q4 Hyperacidity: 1-2tabs after meals 2-4tabs 20min-1hr after meals & HS 2-4tsp QID; Max: 16tsp 2-4tab or tsp susp QID after meals & HS
DOSE 1-30mo: 1/4ml QID 4-6mo: 1/2ml QID 7-12mo: 3/4ml QID 1-2yrs: 1ml QID 2-6yrs: 1/2tsp QID 7-12yrs: 1tsp QID
NaCL
PREPARATIONS Chewable tab: (KREMIL-S)
Chewable tab: 200mg/200mg Susp: 200mg/225mg/5ml Chewable tab: 200mg/200mg/25mg Susp: 200mg/225mg/25mg/5ml
PREPARATIONS Drops: 6.25mg/ml Syrup: 12.5mg/ml (DISUDRIN)
0.1mkdose TID-QID 2-4yrs: ¾tsp 4-12yrs: 1tsp >12yrs: 1-2tsp
Drops Pedia syrup Syrup (DIMETAPP)
1-6yrs: 1tsp 6-12yrs: 2tsp >12yrs: 1cap or 1tbsp BID 2-4gtts/nostril TIDQID Spray enough amount in each nostril
Syrup: 1.3mg/16.6mg/5ml Cap: 4mg/20mg (RHINOPRONT)
ANTI-CONVULSANTS DRUGS DOSE PHENOBARBITAL LD: 10-20mg/kg IV MD: 5-8mkDay q12 PO, IV Max: 1-2g
Pedia nasal drops: 0.65% Spray: 0.65% (SALINASE)
PREPARATIONS Grain 1 tab = 65mg Tab: 15, 30, 60, 90mg PhilUSA Vial: 130mg/ml vial
PHENYTOIN
LD: 10-20mg/kg IV MD: 5-8mkDay q12 PO, IV Max: 1g
Susp: 30mg/5ml, 125mg/5ml Vial: 100mg/2ml Cap: 30mg, 100mg (DILANTIN)
DIAZEPAM
0.2-0.5mkdose IV 0.3mkdose RECTAL Max: <5yrs: 5mg >5yrs: 10mg
Tab: 2mg, 5mg, 10mg Vial: 10mg/2ml (VALIUM)
MUCOKINETICS/EXPECTORANTS DRUGS DOSE AMBROXOL 1.2-1.6mkDay Pedia Syrup or syrup: 1-2yrs: 1/2tsp BID 2-6yrs: 1/2tsp TID 6-12yrs: 1tsp BID-TID >12yrs: 1tab/ 1-2tsp TID
PREPARATIONS Infant drops: 7.5mg/ml >6mo: 0.5ml BID 7-12mo: 0.75ml BID 13-14mo: 1ml BID Pedia syrup: 15mg/5ml Syrup: 30mg/5ml (AMBROLEX)
BROMHEXINE
<2yrs: 1.25ml TID 2-6yrs: 2.5ml BID or 4mg tab 6-12yrs: 5ml TID or 4mg tab >12yrs: 10ml TID or 8mg tab
Elixir syrup: 4mg/5ml Tab: 8mg (BISOLVON)
CARBOCISTEINE
1-3mo: 0.5ml TID 3-6mo: 0.75ml 6-12mo: 1ml 2-3yrs: 1/2tsp TID 4-7yrs: 1tsp TID 8-12yrs: 1 ½tsp TID >12yrs: 1 cap TID or 1-2tsp TID
Drops: 40mg/ml Syrup: 200mg/5ml Forte susp: 500mg/5ml Cap: 500mg (SOLMUX)
SALBUTAMOL, CARBOCISTEINE
2-6yrs: 1/2tsp TID 7-12yrs: ½-1tsp TID >12yrs: 1cap or 12tsp
Susp: 2mg/500mg/5ml Cap: 2mg/500ml (SOLMUX BRONCHO)
SALBUTAMOL, GUAIFENESIN
<2-6yrs: 1tsp BID-TID 6-12yrs: 2tsp or 1cap BIDTID >12yrs: 2tsp or 1-2 cap BIDTID
Syrup: 50mg/1mg Cap: 100mg/2mg (VENTOLIN EXPECTORANT)
PENTOXYVERINE
Syrup: 1ml TID 4-6tab/day
Syrup: 7.5mg/5ml Tab: 25mg
ANTI-KOCH’s DRUGS ISONIAZID
DOSE 5-10mkDay OD PO
PREPARATIONS TRISOVIT: 50mg/5ml NICETAL: 100mg/5ml ODINAH: 150mg/5ml COMPRILEX: 200mg/5ml
RIFAMPICIN
10-15mkDay OD PO
RIFAMAX DROPS: 100mg/5ml RIMACTANE, RESIMIN, RIFASIN: 100mg/5ml RIFAMAX, RESIMIN, RIFACIN, RIMACTANE FORTE: 200mg/5ml
PYRAZINAMIDE
15-30mkDay OD PO
250mg/5ml; 500mg tab (PZA-CIBA)
STREPTOMYCIN
20-30mkDay OD IM
1g/vial
ETHAMBUTOL
15-25mkDay OD
Cap: 200mg, 400mg
ANTI-ASTHMA DRUGS SALBUTAMOL
DOSE 0.15-0.30mkdose q6
PREPARATIONS Syrup: 2mg/5ml
PREPARATIONS Syrup: 0.25mg/2mg/5ml Tab: 0.25mg/2mg (CELESTAMINE)
ANTI-SPASMODIC – caution for children <6yrs, NOT used often DRUGS DOSE PREPARATIONS DICYCLOVERINE Infants: 1/2tsp TID Syrup: 10mg/5ml Pedia: 1tsp TID Tab: 10mg Tab: 2-12yrs: 1-2tabs or ½tab 15 min before feeding TIDQID HYOSCINE Pedia: 5mg TID IV Vial: 20mg/ml (BUSCOPAN) N-BUTYLBROMIDE DECONGESTANTS DRUGS PHENYLPROPANOLAMI NE
BROMPHENIRAMINE MALEATE + PHENYLEPHRINE + PHENYLPROPANOLAMI NE CARBINOXAMINE RESINATE, PHENYLPROPANOLAMI NE
PO
Tab: 2mg Nebule: 2.5mg/2.5ml, 5mg/2.5ml
TERBUTALINE
0.075mkdose q6 PO
HYDROCORTISON E
LD: 10-20mg/kg IV MD: 5-8mkdose q6 IV
Syrup: 1.5mg/5ml Nebule: 5mg/2ml (BRICANYL) Vial: 100mg/vial ***give H2 blocker
PREDNISONE
0.5-2mkDay PO x 3 days
Tab: 5mg, 20mg ***give H2 blocker ***taper dose!
EMPIRICAL DOSAGES <6mos 6mos – 2yrs 2 – 6yrs 6 – 9yrs 9 – 12yrs
1/4tsp TID – QID 1/2tsp 1tsp 1 ½tsp 2 tsp
ELEMENTAL IRON:
therapeutically given for 1 month: TD: 6mkDay OD Maintenance given for 2 months: MD: 3mkDay OD
FLUID LIMITATION:
BSA x (400-600) x urine output
ALLOWABLE BLOOD LOSS:
WT x 80 (blood volume) x 0.10
ANC:
NV: 2,000 – 6,000 >6,000: bacterial <2,000: viral <500: immunocompetent
WBC x SEG + STAB
FOR CANDIDIASIS:
Econazole NO3 (PEVARYL) cream 10mg/g Econazole NO3 + Zn Oxide (PEVARYL HP) 10mg/100mg BID x 14-21 days for candidiasis
DOSE (ml) = Wt (kg) x TD x Preparation (inverse) Frequency THERAPEUTIC DOSE = Dose x Preparation x Frequency Wt (kg) *** frequency is not included in the computation of drugs w/ TD of mkdose such as Paracetamol *** for IV meds, preparation is not included in the computation. IV MEDS = mg
