January, 2015 2015 1) Which of the following following is one one of the ankle bones? bones? a) Car Carpals als b) Tarsa ar sals ls c) atel atella la 2) !nta !ntaraar raarticu ticular lar in"ect in"ection ion is in # a) $one b) Joint c) %pine &) hear artt e) ar artter ery y ') Which of the the following organ organs s foun& in the left si&e of the the hu(an bo&y? bo&y? a) i*er b) %p %ple leen en c) +ppen en&i &i &) $la la& &&er -) .ilk allergy allergy is is an a&*erse a&*erse i((une i((une reaction reaction to # a) Ca Calc lciu iu( ( b) ac acto tos se c) ro rote tein in &) /it ita( a(in in e) +( +(in ino o +ci +ci& & 5) When a *agal *agal sti(ulation sti(ulation occurs, occurs, which of these these substances will will be release&? release&? a) opa opa(i (ine ne b) %ero %eroto toni nin n c) !nsulin &) /asopr asopress essin in e) +cetyl +ce tylcho cholin line e ) a(ci a(ciclo*i clo*irr is use& use& in # a) 3erpes 3erp es si( si(ple ple b) wes westt 4ile 4ile *ir *irus us c) $ac $acter teria iall infe infecti ction on &) ungal infection ) +ll of the following following are are a seual6trans(itte seual6trans(itte& & &isease 7cept 7cept # a) Tricho(o richo(onia niasis sis b) 3erpe 3erpes s si( si(pl ple e c) 3erpes 3e rpes 8oster 8ost er &) 9ono 9onorrrhea rhea :) The (ost (ost co((o co((on n 9!T &isor &isor&er &er is # a) 8oli 8olinger nger67lli 67llison son syn&ro syn&ro(e (e b) ep epti tic c ;lce ;lcerr c) 9ast 9astro7soph ro7sophogeal ogeal
age age 1 >f -0
January, 2015 2015 ) or a patient patient taking +cetylsalicyli +cetylsalicylic c +ci& '50 (g, which which of these patients patients is the least to cause gastric blee&ing? @ C37CA ) a) Tak ake e it with foo& b) atie atient nt o*er o*er 0 yea years rs ol& c) Taken 4apro 4aproen en at at the sa(e ti(e 10) a) b) c) &)
+ll of the following following can be taken with or after after foo& 7cept 7cept # %ucral %uc ralfa fate te re&i re&inso nsolon lone e osarta artan n Carba Carba(aB (aBip ipine ine
11) a) b) c) &)
Which of the following (e&ication for treat(ent of glauco(a is taken orally? +cetaB +ce taBola ola(i& (i&e e orB o rBal alo( o(i& i&e e pilo pi loca carp rpin ine e latano lat anopr prost ost
12) a) b) c) &)
Which of of these (e&icatio (e&ications ns cause iris pig(entation pig(entation? ? Carboni Carb onic c anhy&ra anhy&rase se inhibito inhibitors rs rostagla ros taglan&ins n&ins 2 analog +&rener +&r energic gic ant antago agonist nist Choline Chol inergi rgic c ago agonist nist
1') inoleic aci& aci& D inolenic inolenic aci& are are structurally structurally &iEer in in # a) 4u(be 4u(berr of &oubl &ouble e bon& b) %te %tere reoch oche(i e(istr stry y @4F$# The position of the &ouble bon& was not one of the choices ) 1-) a) b) c) &)
Which of the following is not not a sy(pto(s sy(pto(s of
15) a) b) c) &) e)
3Fylori treat(ent 3Fylori treat(ent inclu&e inclu&e all the the following following 7cept 7cept # .etro .et roni& ni&aBo aBole le Clari Cla rithr thro( o(yci ycin n +(o +( oi ici cill llin in Tetra etracycl cycline ine /anco( /anc o(yc ycin in
1) a) b) c) &)
+ll are are use& in treat(ent treat(ent of acute acute gout 7cept # +ceta( +ce ta(ino inophe phen n re& re&ni niso sone ne Cele Celeco coi ib b Colc Colchi hici cine nes s
January, 2015 2015
age age 2 >f -0
January, 2015 2015 ) or a patient patient taking +cetylsalicyli +cetylsalicylic c +ci& '50 (g, which which of these patients patients is the least to cause gastric blee&ing? @ C37CA ) a) Tak ake e it with foo& b) atie atient nt o*er o*er 0 yea years rs ol& c) Taken 4apro 4aproen en at at the sa(e ti(e 10) a) b) c) &)
+ll of the following following can be taken with or after after foo& 7cept 7cept # %ucral %uc ralfa fate te re&i re&inso nsolon lone e osarta artan n Carba Carba(aB (aBip ipine ine
11) a) b) c) &)
Which of the following (e&ication for treat(ent of glauco(a is taken orally? +cetaB +ce taBola ola(i& (i&e e orB o rBal alo( o(i& i&e e pilo pi loca carp rpin ine e latano lat anopr prost ost
12) a) b) c) &)
Which of of these (e&icatio (e&ications ns cause iris pig(entation pig(entation? ? Carboni Carb onic c anhy&ra anhy&rase se inhibito inhibitors rs rostagla ros taglan&ins n&ins 2 analog +&rener +&r energic gic ant antago agonist nist Choline Chol inergi rgic c ago agonist nist
1') inoleic aci& aci& D inolenic inolenic aci& are are structurally structurally &iEer in in # a) 4u(be 4u(berr of &oubl &ouble e bon& b) %te %tere reoch oche(i e(istr stry y @4F$# The position of the &ouble bon& was not one of the choices ) 1-) a) b) c) &)
Which of the following is not not a sy(pto(s sy(pto(s of
15) a) b) c) &) e)
3Fylori treat(ent 3Fylori treat(ent inclu&e inclu&e all the the following following 7cept 7cept # .etro .et roni& ni&aBo aBole le Clari Cla rithr thro( o(yci ycin n +(o +( oi ici cill llin in Tetra etracycl cycline ine /anco( /anc o(yc ycin in
1) a) b) c) &)
+ll are are use& in treat(ent treat(ent of acute acute gout 7cept # +ceta( +ce ta(ino inophe phen n re& re&ni niso sone ne Cele Celeco coi ib b Colc Colchi hici cine nes s
January, 2015 2015
age age 2 >f -0
January, 2015 2015 e) !n&o !n&o(e (eth thac acin in 1) a) b) c) &) e)
ysoso(es are are responsible responsible for for cellular# cellular# rote r otein in for(at for(atio ion n 7nergy 7ner gy pr pro&u o&uctio ction n 7n By(e &iges 7nBy(e &igestion tion Tran ranspor sportt of 4+ er(eability
1:) a) b) c) &)
.itochon&ria is an organ .itochon&ria organelle elle that that responsible responsible for # or( o r(atio ation n of of protei protein n ro&uct ro&u ction ion of +T igest ig estio ion n of en enBy( By(es es Tran ranspor sportati tation on of 4+ 4+
1) Which of the following following enBy(es enBy(es is responsible responsible for phosphorylation phosphorylation of a(ino a(ino aci&s? a) Aina Ai nas se b) yase yase c) 7ste 7sterrase &) %ynt %ynthe heta tase se 20) 3ow (any cis cis &ouble bon& bon& can be foun& foun& in that that structure? structure?
a) b) c) &) e)
0 1 2 ' -
21) .etfor(in .etfor(in is foun& in 2 che(ical che(ical structure structure which are are #
D a) b) c) &)
, what is the relationship in between
these 2 structures? Tauto au to(e (ers rs Con"ug Con"ugate ate aci&Gb aci&Gbase ase oly( oly(or orph phis is( ( %truct %tructur ural al iso(er iso(ers s
22) 22) This This struct structur ure e is?
January, 2015 2015
age age ' >f -0
January, 2015
a) b) c) &)
henothiaBine Tricyclic +nti&epressant $enBo&iaBepines +ntihista(inic
2') a) b) c)
uring the (etabolis( of purine bases which of these co(poun& is for(e&? 3ypoanthine +Bathioprine .ercaptopurine
2-) a) b) c) &) e)
+ patient with high urinary ;robilinogen , that in&icate a &isease in# $la&&er Ai&ney i*er 3eart ancreas
25) >ral /anco(ycin is use& in case of # a) .<%+ b) seu&o(e(braneous colitis cause& by Clostri&iu( &iHcile 2) a) b) c) &) e) 2) a) b) c) &)
Which of these *accines is a&*ise& to pre*ent tra*eller &iarrhea? Cholera *accine 3epatitis + /accine 3epatitis $ /accine
2:) a) b) c) &)
neu(onia6causing bacteria pathogens inclu&e all of the below 7cept # %treptococcus pneu(oniae .oraella catarrhalis $acteroi&es fragilis 3ae(ophilus in=uenBae
2) a) b) c)
Which of the following is a sy(pto( of chronic bronchitis? ro&ucti*e sputu( cough yspenia 4on pro&ucti*e cough
'0) What is the treat(ent of chronic sinusitis? January, 2015
age - >f -0
January, 2015 a) +(oicillin6cla*ulanic aci& b) e*o=oacin c) +Bithro(ycin '1) a) b) c) &)
+ '0 year ol& (an has gonorrhea, what is the appropriate treat(ent? CeIi(e followe& by aBithro(ycin Ceftriaone 4itrofurantoin +(picillin
'2) + 0 years ol& wo(an with gout , which of the following antihypertensi*e agent (ust not be use& # a) 3y&rochlorothiaBi&e b) +C76! c) +<$s &) $6$lockers '') what antihypertensi*e agent use& for (il& to (o&erate hypertensi*e patient with congesti*e heart failure # a) 4ife&ipine b) /erapa(il c) abetolol &) 3y&rochlorothiaBi&e '-) Which of the following cause pneu(onia # !F %treptococcus neu(onaie !!F 3ae(ophilus !n=uenBae !!!F %taphF aureus a) ! >nly b) !!! >nly c) !, !! >nly &) !! , !!! >nly e) +ll answers '5) a) b) c) &)
ipase ele*ation in&icates a &isease in # ancreas i*er 3eart Ai&ney
') a) b) c) &)
atient with a proble( in *al*e of the heart can be &iagnose& by # 7chocar&iogra( 7lectrocar&iogra( $loo& pressure (easure 7ercise 7lectrocar&iogra(
') The &eoygenate& bloo& go to the right atriu( of the heart fro( all the bo&y through # a) ul(onary *ein January, 2015
age 5 >f -0
January, 2015 b) Caroti& artery c) +orta &) %uperior /ena Ca*a ':) a) b) c) &) e)
ehy&ration can cause all 7cept # Thirst iBBiness 3ea&ache 3ypertension ry skin
') a) b) c) &)
re6ecla(psia is characterise& by # 3ypertension 3ypotension 3yperglyce(ia 3ypoglyce(ia
-0) a) b) c) &) e)
-1) a) b) c) &) e)
Which can re&uce car&iac oygen &e(an& without causing *aso&ilatation? +tenolol elo&ipine 4itroglycerine .inoi&il 3y&ralaBine
-2) a) b) c)
Which of the following cause *enous pooling? 4itrates 4ife&ipine igoin
-') a) b) c) &) e)
4+ is nee&e& for # $iotin 4iacin
--) a) b) c) &) e)
Which *ita(in (ay cause =ushing? /ita(in $1 /ita(in $2 /ita(in $' /ita(in $ /ita(in $
January, 2015
age >f -0
January, 2015 -5) Which is true about 4iacin 7cept # a) 4iacin &ose as lipi& lowering agent is so s(all b) 3epatic 7nBy(e ele*ation cause by niacin in tablet for( -) +ll of the following are an appropriate a&*ices for a la&y suEers fro( hot =ash 7cept # a) ight 7ercise b) Take 0F5 (g +spirin c) ight cloths &) ;se fan -) a) b) c) &)
+ll are appropriate a&*ices for hae(orrhoi& patient 7cept # +*oi& taking aci& fruit "uice +*oi& hea*y lifting +*oi& straining +*oi& sitting for long perio&s
-:) a) b) c)
%(oking in pregnancy (ay aEects fetus by # 4euro &isor&er ung not for(e& well !nterrupt >ygen transfer through the placenta
-) what is the property of the &rug that can be foun& in breast tissue with high concentration a) ow .olecular Weight b) ow ipi& %olubility c) 3igh rotein $in&ing &) 3igh +ci&ic pro&uct 50) a) b) c) &)
When a &rug circulating in bloo& D highly perfuse organs, we na(e it # Central Co(part(ent eripheral Co(part(ent 26 Co(part(ent .ulti Co(part(ent
51) a) b) c)
!n en& stage renal failure Calciu( is gi*en to #
52) a) b) c) &)
!nterleukins D T4 are consi&ere& # Cytokines 7nBy(es rostaglan&ins eukotrienes
5') >+T D >CT are consi&ere& # January, 2015
age >f -0
January, 2015 a) Cytokines b) Transporters c) 7nBy(es 5-) a) b) c)
The test to &etect pyrogen in the parenteral preparations is calle& # i(ulus test Coo(bs test %chilling test
55) a) b) c) &) e)
e(yelination is a characteristic for # .ultiple %clerosis iabetic foot
5) a) b) c) &)
What is true about the %ciatic ner*e? @ C37CA ) inner*ate the whole foot inner*ate the 3ips inner*ate the $uttocks large (uscle inner*ate the Kua&riceps
5) estruction of the ra&ial ner*e (ay cause # a) iHculty straightening the elbow b) iHculty (o*ing the shoul&ers 5:) a) b) c) &) e)
9lutathione is (a&e up of 9luta(ate , 9lycine an& # Cysteine ysine +lanaine Tryptophan henylalanine
5) a) b) c) &) e)
!n the 7C9 , /entricular &epolariBation is in&icate& by # Wa*e < !nter*al K<% Co(ple %T %eg(ents KT !nter*al
0) +ngiogenesis (eans # a) or(ation of new bloo& *essels b) or(ation of new bone c) or(ation of new
age : >f -0
January, 2015 cF Thy(us 9lan& &F +&renal Corte b) ineal 9lan& 2) +ll of the following use& in treat(ent of breast cancer 7cept # a) +nstraBole b) etraBole c) Ta(oifen &) $lucta(i&e e) 7e(estane ') e*othyroine is use& in the treat(ent of hypothyroi&is( by # a) +ct as a replace hor(one b) !ncrease con*ersion of T- to T' c) !ncrease synthesis of Thyroin -) Which is true about iabetes? a) 9lucagon D !nsulin ha*e opposite eEect on glucose (etabolis( b) .etfor(in causes hypoglyce(ia c)
age >f -0
January, 2015 ) What is the (echanis( of action of ropylThiouracil in the treat(ent of hyperthyroi&? a) !nhibit the synthesis of T%3 b) !nhibit the synthesis of thyroin c) !ncrease the con*ersion of T' to T0) Which of the following is a sy(pto( of hypothyroi&is(? a) 3eat intolerance b) ry %kin c) Tachycar&ia &) iarrhea e) Weight loss 1) ecrease in +3 (ay cause # a) loy urea b) >ligurea c) olyhagia &) rotein in urine 2) +ll of the following are a sy(pto(s of %eptic shock 7cept # a) e*er b) Tachycar&ia c) !ncrease ;rine /olu(e &) 3ypotension ') Which of the following pro&ucts acts as 56 re&uctase inhibitor? a) inasteri&e b) Ta(sulosin c) raBosin -) Which of the following pro&ucts use& to shrink the siBe of the prostate in $3? a) inasteri&e b) Ta(sulosin c) raBosin 5) +ll of the following are factors that aEect the creatinine clearance 7cept # a) +ge b) 9en&er c) Weight &) seru( creatinine e) ;rine *olu(e ) What is true about a(ino glycosi&e? a) ;se& in the treat(ent of pneu(onia cause& by pseu&o(onas aeruginosa ) What is true about ost +ntibiotic 7Eect? a) The &rug still has the power to pre*ent the growth of (icroorganis(s after &uration of a&(inistration b) +(ino glycosi&es are an ea(ple against anaerobic (icroorganis(s January, 2015
age 10 >f -0
January, 2015 :) Which of the following pro&ucts is suitable for a patient suEer fro( &epression an& neuropathic pain? a) +(itriptyline b) $upropion c) %elegiline &) aroetine e) .irtaBapine ) What is the &uration of treat(ent nee&e& for a patient with a Irst episo&e of (a"or &epression? a) ' (onths b) (onths c) 1 year &) 2 years e) 4o ti(e li(it :0) rug M has a clearance of '00 (lG(in while the nor(al clearance rate is 120(lG(int his in&icate # @ Check ) a) !ncrease 9< an& acti*e ecretion b) !ncrease 9< an& reabsorption c) !ncrease acti*e ecretion &) !ncrease 9< :1) What is the appropriate a&*ice for a patient will use oral corticosteroi& for a (onth? a)
age 11 >f -0
January, 2015 &) 9lucose le*els e) %eru( hosphates :5) .orphine cause respiratory &epression &ue to its action on which receptor # @ Check ) a) .u b) Aappa c) elta &) .u D Aappa e) .u D elta :) +ll of the following cause hyperkale(ia 7cept # a) /o(iting b) %piranolactone c) +<$s &) +C76! e)
' b) !ncrease in C>2 pressure c) ecrease *entilation :) 4aturally occurring progra((e& cell &eath is known as# a) 4ecrosis b) +poptosis c) +trophy &) .itosis e) Cytosis 0) The process by which the neutrophils kill the strange cells in the seru( by engulIng is calle& a) hagocytosis 1) What are the (ost abun&ant white bloo& cells in the bloo&? a) .onocytes b) $asophiles c) 4eutrophils &) latelets e) .acrophages 2) Which is responsible for the (etabolis( of (ercaptopuric aci&? a) CN'+b) 9lucuronic aci& c) 9lutathione % Transferase January, 2015
age 12 >f -0
January, 2015 &) 4+$K! e) $ilirubin ') Which of the following glucourni&e (etabolite is acti*e # a) Co&eine b) igoin c) $eta $locker -) Jaun&ice in newborns is cause& fro( a &eIciency of# a) 9lucose b) ; glucose c) 9lucuronate &) ; glucuronate e) ; glucuronyl transferase 5) +ll of the following agents use& to treat the nausea an& *o(iting cause& after che(otherapy 7cept # a) .etochlopra(i&e b) ea(ethaBone c) >n&ansetrone &) erchloperaBine e) oyla(ine ) Which of the following che(otherapeutic agents acts by inhibit the synthesis an& for(ation of 4+# a) Cisplatin b) 56lurouracil c) /incristine &) 6+spraginase e) 7topsoi&e ) atient with chronic C> an& ha& pneu(onia , before he ha& pneu(onia an& took a(oicillin Cla*ulonate since 2 (onths , what is the e(pirical treat(ent # @ Check ) a) +(oicillin Cla*ulonate b) Clarithro(ycin c) oycycline &) e*o=oacin :) !n Can&i&a we can use all the following agents 7cept # a) luconaBole b) .etroni&aBole c) AetoconaBole &) 4ystatin e) +(photericin $ ) The &rug of choice for treat(ent of athletes foo& is # a) Clotri(aBole January, 2015
age 1' >f -0
January, 2015 b) oly(iin $ c) 9er(ici&in &) $acteriocin 100) Treat(ent of i(petigo in a 10 years patient # a) >ral erythro(ycin b) >ral a(oicillin c) Topical (upricine 101) atient with se*ere ulcerati*e colitis , what will be use& to re&uce re(ission # a) !n=ii(ab b) re&nisone c) +Bathioprine 102)
a) b) c) &)
This structure is foun& in #
Cephalosporins Kuinolone Tetracycline .acroli&es
10') a) b) c) &) e)
Which antibiotic works by inhibiting cell wall synthesis? +(inoglycosi&es Cephalosporins .acroli&es incosa(ines Tetracyclines
10-) a) b) c) &) e)
Which &rug causes &ry (outh? Tiotropiu( ilocarpine +cetylcholine hysostig(ine 4eostig(ine
105) a) b) c) &)
Which of the following gi*e arkinsonis( eEect# aroetine 3aloperi&ol ithiu( CloBapine
10) +cute ystonia cause& by antipsychotics treate& by # a) $enBotropine 10) + phar(acist plans a strategic plan so he &e*elops a %W>T analysis, what &oes the > stan& for in this case? January, 2015
age 1- >f -0
January, 2015 a) >pportunity b) >utco(e c) >b"ecti*es 10:) a) b) c) &) e)
Which is not a sy(pto( of rhinitis
10) What is the &iEerence between ;rinary Tract !nfection D ;nco(plicate& ;rinary Tract !nfection #@? Check ) a) ain sensation &uring urination b) reuency of urination c) ;rgency of urination &) Turbi&ity of urine e) e*er 110) Which of the following herbal re(e&y can be use& in treat(ent of (igraine? a) icorice b) Chrysanthe(u( c) %tF JohnLs wart &) 9ua*a e) 9inkgo 111) a) b) c) &) e)
%u(atriptan is use& in treat(ent of (igraine &ue to its eEect as opa(ine antagonist 53T1bG1& agonist +cetylcholine antagonist 53T1bG1& antagonist opa(ine agonist
112) a) b) c) &) e)
11') Which of the following factors aEect on the passage of a &rug through the stratu( corneu(? a) %olubility b) issolution c) Aa &) artition CoeHcient e) article siBe January, 2015
age 15 >f -0
January, 2015 11-) a) b) c) &) e)
Too (uch pressure n tablet &uring (anufacture causes # Capping a(ination icking %ticking .ottling
115) a) b) c) &)
Which of the following is a water soluble oint(ent base? anoline Nellow wa %o&iu( .onostearate 79 '000 D 79 000 .iture
11) a) b) c) &) e)
%albuta(ol is # $1 +gonist $2 +gonist $ 4on %electi*e agonist $1 +ntagonist $2 +ntagonist
11) a) b) c) &) e)
ilgrasti( use& in patients recei*ing strong che(otherapy to # rotect the( fro( +lopecia
11:) a) b) c) &) e)
Cytochro(e oi&ase D >ygen transport contain# .yosin .yoglobin 3e(e +lbu(in Transferrin
11) Which of the following bloo& co(ponent which are i(portant in &rug bin&ing? a) +lbu(in D / b) +lbu(in D 9lycoprotein c) <$CsD W$Cs 120) 3igh 7traction ratio is present in #@ Check ) a) 3igh Irst pass eEect b) 8ero >r&er c) %econ& >r&er @4F$# 4o Irst or&er a(ong the choices)
January, 2015
age 1 >f -0
January, 2015 121) The Aaplan6.eier euation is applie& for new therapies @such as &ialysis or antineoplastics) to (easure patientsO# a) references b) +&*erse reaction rate c) .ortality rate &) .orbi&ity rate e) %ur*i*al rate 122) What is true about the che(ical structure of !((unoglobulin? @ Check ) a) Contains hea*y an& light chain connecte& by &isulI&e bon& b) Consists of four subunits connecte& together by hy&rogen bon& 12') Which of the following &rugs (ay reuire (onitoring the eye of the patient? a) henytoin b) 3y&roychlorouine c) Caraba(aBepine &) 3aloperi&ol 12-) a) b) c) &)
+ll of the following pro&ucts cause pul(onary Ibrosis 7cept # +(io&arone igoin $leo(ycin $ro(ocriptine
125) What is the best treat(ent of +3 @+ttention eIcit 3yperacti*ity isor&er)# a) .ethylpheni&ate b) +(pheta(ines c)
/enlafaine acts on which receptors # %erotonin opa(ine 4orepinephrine %erotonin D opa(ine %erotonin D 4or epinephrine
12) a) b) c) &)
Which of these (e&ications not to be taken with e*othyroine ?@ Check ) errous gluconate >(epraBole henytoin Carba(aBepine
12:) /ita(in 7 after >i&ation in lipi& bi layer, returns to its re&uce& for( by the action of # a) /ita(in + January, 2015
age 1 >f -0
January, 2015 b) c) &) e)
/ita(in $12 /ita(in C /ita(in A /ita(in
12) /ita(ins are # a) >rganic substances thatFFFFF b) !norganic substances that (ust be taken &aily to act in biological functions c) !norganic substances that act as a cofactor in the enBy(atic reactions 1'0) a) b) c) &)
ysphasia is i(paire& in# %peech Taste yspepsia %(ell
1'1) a) b) c) &) e)
+ patient taking Warfarin, u shoul& (onitor # +ppt !4< $p 3eart rate /ita(in A ConcF
1'2) a) b) c) &)
What is true about Troponin? ;se& to &iagnose Car&iac infarction &iseases oun& in Car&iac an& s(ooth (uscles ;se& to &etect hepatic &iseases ;se& to e*aluate the renal function
1'') a) b) c) &)
What is true about 4icotine
1'-) While using !sotretonin , we shoul& (onitor # a) 3ae(oglobin D ipi& le*el b) ipi& D i*er c) Ai&ney 1'5) a) b) c) &) e)
+ < contains %o&iu( $isulIte which is use& as # +nti6>i&ant ubricant 3u(ectants %olubilising +gent reser*ati*e
1') To increase the solubility of organic salt an& protein by increasing the ion strength this is calle& # January, 2015
age 1: >f -0
January, 2015 a) %alting !n b) %alting >ut c) Co %ol*ency 1') a) b) c) &) e)
Which of the following can be use& to pre*ent /T in a pregnant wo(an? /ita(in A antagonist therapy alteparin 3eparin then Warfarin Warfarin on&aparinu
1':) What is (eant by unctional foo& ?@ Check ) a) Cereals contain (ulti*ita(ins b) Jelly contain (ineral oil c) Tabs or caps for *ita(ins an& (ineral oil 1') a) b) c) &)
Which of the following can be use& in treat(ent of $F fargilis !nfection? .etroni&aBole Clarithro(ycin Tetracycline AetoconaBole
1-0) a) b) c) &) e)
%taphF +ureus can be foun& in colonies in chronic infection of #@ Check ) 7ar 7ye 4ose ingernail %ore
1-1) a) b) c) &)
1-2) + (other of a ' years ol& baby ca(e to the phar(acy with a prescription of +(oicillin to treat otitis (e&ia for her baby but you notice that the &ate of the prescription was ' &ays later, what is the appropriate action you ha*e to follow? a)
rug of choice for the treat(ent of (eningitis in a&ult is # Ceftriaone CeIi(e Cephalein Cefuroi(e
January, 2015
age 1 >f -0
January, 2015 1--) a) b) c) &) e)
The Irst line treat(ent for ain in >steoarthritis is# .orphine !buprofen +ceta(inophen !n&o(ethacin Celecoib
1-5) What is true about Co&on # a) resent in t<4+ b) Consists of ' nucleoti&e bases that epress 1 a(ino aci& c) !tLs a seg(ent of 4+ epress genes 1-) %4 .eans # a) %ingle 4on6oly(orphis( b) Change in one base in 4+ 1-) a) b) c) &)
1-:) a) b) c) &)
The process in which 4+ is con*erte& to (<4+ is calle& Translation Transcription
1-) a) b) c) &) e)
The following is contrain&icate& with celecoib# &yspepsia sulfa allergy prostatic hyperplasia renal i(pair(ent aceta(inophen concurrent use
150) a) b) c) &) e)
!n the 4orthern 3e(isphere the (ost suitable perio& to take =u *accine is # %epte(ber till .i& ece(ber %epte(ber till .i& >ctober >ctober till .i& ece(ber 4o*e(ber till .i& January 4o*e(ber till .i& +pril
.i& .i& .i& .i& .i&
151) a) b) c) &) e)
!n case of 3eparin o*er&ose, what is the correct anti&ote? rota(ine %ulfate /ita(in A Warfarin 4a bicarbonate +tropine
January, 2015
age 20 >f -0
January, 2015 152) a) b) c) &) e) 15') a) b) c) &)
Ta&alaIl is &iEerent fro( %il&enaIl because# sil&enaIl is longer acting Ta&alaIl is shorter acting Ta&alaIl can be use& safely with nitroglycerin Ta&alaIl an& %il&enaIl are both eually acti*e an& ha*e the sa(e &uration Ta&aliIl is (uch longer acting than %il&enaIl The %tea&y6%tate Concentration is a factor of # +;C 3alf life las(a rotein bin&ing ose
15-) $y &i*i&ing the a(ount of the &rug in the bo&y by the concentration of the &rug in the plas(a , we will get # a) /olu(e of istribution b) Clearance
What the (ost sy(bol take the phar(acist attention in
15:)
< %ubstance M 3y&rocortisone 1 Q ++ 25 (g .itte 50 (g What &oes ++ refer to? a) 7ual a(ount of each b) +cceptable a(ount up to c) +ppropriate a(ount up to
15) 250 (g of %ubstance M 50 Q nee&e& to be &ilute& to be 10 Q, how (any (g &iluents shoul& be a&&e&? a) 1000 (g January, 2015
age 21 >f -0
January, 2015 b) 1250 (g c) 50 (g 10) a) b) c) &)
Which of the following preparation (ust be co(pletely steriliBe&? Total arenteral 4utrition >ral %uspension 4asal preparation
11) 3ow (any (ill eui*alent of CaCl2 is foun& in 1000 (g @Ca ato(ic weight -0)? a) 25 b) 50 c) 100 12) + pro&uct with T1G2 P 2 hrF was gi*en as 250 (g e*ery 12 hrF , we notice that that pro&uct is not accu(ulate& in the bo&y because of # a)
ung thro(bus is (ainly &ue to# ibrin latelets C protein <$Cs W$Cs
1-) a) b) c) &) e)
Thali&o(i&e use& to treat # .ultiple here&itary eostosis .ultiple en&ocrine neoplasia .ultiple syste( atrophy .ultiple sclerosis .ultiple (yelo(a
15) a) b) c) &)
.ycophenolate (ofetil is an # +ntifungal +ntihel(inthics +nti +rrhyth(ia !((unosuppressant
1) !f ro&uct + is shown to has +;C of 50 When gi*en as a &ose of 50 (g orally , While ro&uct $ has +;C of 0 when gi*en as a &ose of 100 (g orally , what is the relati*e bioa*ailability of pro&uct $ to ro&uct + ? a) 0F b) 1F1 January, 2015
age 22 >f -0
January, 2015 c) 1 1) !f ro&uct + is gi*en as a &ose of 150 (g shows +;C of 50 with C (a 50 (g D T (a 1hrF D ro&uct $ is gi*en as a &ose of '00 (g shows +;C of 50 with C (a 50 (g D T (a hrF What is true about ro&uct $? a) %ustaine& r&er b) irst >r&er c) %econ& >r&er 1) !n a clinical trial the absolute risk re&uction was 5 Q Then what will nu(ber nee&e& to treat # a) 2 b) 20 c) 200 &) 10 e) 100 10) a) b) c) &) e)
+ll of the following are enBy(e in&ucer 7cept # /alproic +ci&
11) What is the relation of Co&eine to .orphine? a) Co&eine is a pro6&rug of .orphine b) They are functional iso(ers c) They are structural iso(ers 12) a) b) c) &) e) 1') a) b) c) &)
+ll the following &rugs &ecrease the eEects of oral contracepti*es, 7cept #
January, 2015
age 2' >f -0
January, 2015 1-) Which of the following (e&ication (ay cause erectile &ysfunction? a) Corticosteroi& b) +&renergic $locker c) >pioi& &) +C7 !nhibitors 15) Which of the following (e&ication is use& in Congesti*e 3eart ailure an& increase the sur*i*al rate? a) 7nalapril b) igoin c) obuta(ine @4F$# 4o $eta $lockers a(ong the choices) 1) a) b) c) &)
Class ! ant arrhyth(ic pro&ucts act by blocking # 4a Channels Ca Channels otassiu( Channels $eta
1) What is true about Clopi&ogrel? a) !t acts by inhibition of Co6!! b) !t acts by inhibition of TM+2 c) !t acts by antagonise + on its receptors 1:) atient takes age& cheese an& was treate& with .+>6! , he ha& a hypertensi*e crisis because of # a) Tyra(ine b) %erotonin c) 3ista(ine 1) Which of the following (e&ication (ay cause serotonergic syn&ro(e if taken with .+>6! # a) etro(ethorphan b) seu&oephe&rine c) phenylephrine 1:0) a) b) c) &)
Typical antipsychotics act on # opa(ine %erotonin +cetylcholine 4orepinephrine
1:1) a) b) c) &)
Which structure can be for(e& fro( ephe&rine an& pseu&oephe&rine? +(pheta(ine Co&eine .orphine 4iacin
January, 2015
age 2- >f -0
January, 2015 1:2) a) b) c) &) e)
+cetyl %alicylic aci& gets (etaboliBe& into salicylic aci& by# %alicylase 7sterase +(i&ase +cetyltransferase Carboylase
1:') a) b) c) &) e)
Which is use& as local anesthetic for he(orrhoi&s? anolin Witch 3aBel 8inc >i&e 3y&rocortisone ra(oine
1:-) Nou take luticasone inhaler an& also take %albuta(ol inhalerF What instructions (ust your phar(acist tell you regar&ing these two (e&ications? a) Take luticasone, then %albuta(ol then rinseF b) Take %albuta(ol, then luticasone then rinseF c) Take %albuta(ol, rinse, an& then luticasoneF &) Take luticasone, then rinse then take %albuta(ol e) Take %albuta(ol, then luticasoneF 1:5) Why &o we take protein at !/ !n"ection? @ Check ) a) Cause it bin&s faster with the plas(a protein b) To a*oi& Irst pass eEect c) To get a controlle& seru( concentration 1:) a) b) c) &)
.ethylation occurs by the ai& of# %6a&enosine (ethionine 9luta(yl Transferase .onoa(ine >i&ase 7sterase
1:) a) b) c) &) e)
Which *ita(in is foun& only in ani(al6&eri*e& foo&s? /ita(in + /ita(in $1 /ita(in $12 /ita(in /ita(in A
1::) a) b) c) &) e)
Which enBy(e is responsible for the (etabolis( of sil&enaIl? CN1+2 CN2C CN2 CN'+CN'+5
January, 2015
age 25 >f -0
January, 2015 1:) rocess which works by re(o*ing the s(all i(purities fro( plas(a across a se(i6per(eable (e(brane is ter(e&# a) ialysis b) >s(oses c) Concentration 9ra&ient &) ispersion e) iEusion 10) hoto toicity of a (e&ication appears in the for( of # a) ;rticaria b) +llergy c) The skin response rese(bles an eaggerate& sunburn 11) a) b) c) &)
+(orphous for( &iEers fro( crystalline for( as it is # Crystalline !s generally less soluble than a(orphous +(orphous is (ore soluble than Crystalline +(orphous is (ore susceptible to poly(orphis( +(orphous &iEers in the che(ical co(position
12) What is true about the critical (icelle concentration in e(ulsion a) !s &eIne& as surfactant concentration that cause asse(bly b) !t nee&s high a(ount of surfactant when increase lipophilicity 1') a) b) c) &) e)
Which &rugs cause he(orrhagic cystitis# Cyclophospha(i&e /incristine 56lurouracil $leo(ycin .ethotreate
1-) a) b) c) &)
When we a&& a salt to a sol*ent , which is true # !ncrease freeBing point !ncrease *apor pressure !ncrease boiling point ecrease os(otic pressure
15) What is true about aerosol? @ Check ) a) !t can be prepare& for internal an& eternal usage b) !t contains preser*ati*es c) The sa(e Concentration will gi*e the sa(e eEect as oral for( 1) What is (eant by la*igation? 1) +ll of the following instru(ents nee& caution &uring han&ling 7cept # a) %patula b) %yringe c) 4ee&le 1:)
What is true about Coate& Tablets?
January, 2015
age 2 >f -0
January, 2015 !F !!F !!!F a) b) c) &) e)
To protect fro( gastric 3 To (ask the taste To rotect it fro( (oisture in the at(osphere ! >nly !!! >nly ! D !! >nly !! D !!! >nly +ll answers
1) a) b) c) &) e)
To test for a phar(aceuticalOs ability to withstan& abrasion we &o # riability Test Thickness Test 3ar&ness Test issolution Test isintegration Test
200) a) b) c) &) e)
Chro(atography for heat labile substances, all 7cept # Thin ayer Chro(atography 3igh erfor(ance iui& Chro(atography
201) a) b) c) &) e)
olysorbate :0 acts as # %urfactant reser*ati*e 3u(ectants %uspen&ing agent ubricant
202) a) b) c) &) e)
What is true about eutectic (iture? egra&e at roo( te(perature %egregates upon storing iueIes at roo( te(perature Cause 7Eer*escent +bsorb (oisture fro( the at(osphere
20') What is the role of surfactant in suppositories? @ Check ) a) !ncrease water content b) !ncrease contact of suppository with the surroun& c) 7nhance the (elting of the suppository 20-) %e&i(entation rate is &eter(ine& by# a) %tokeLs aw b) ickLs aw c) 4oyes Whitney aw 205) Which of the following (e&ication is use& to treat non6co(plicate& &iaper rash? January, 2015
age 2 >f -0
January, 2015 a) b) c) &)
8inc >i&e Crea( 3y&rocortisone 1 Q +cetyl %alicylic aci& 4ystatin
20) What is true about 7liirs? a) !tLs a sweate& hy&ro alcoholic solution b) !tLs for eternal use only 20) a) b) c) &) e)
What ethics (eans Rpre*ent har(R? $eneIcence 4on6(alfeasance Justice +utono(y /eracity
20:) !f you wai*e the co pay(ent for one of your client because he is a regular custo(er to you an& you &i&nLt &o that with other custo(ers , %o you *iolate # a) $eneIcence b) 4on6(alfeasance c) Justice &) +utono(y e) /eracity 20) a) b) c) &) e)
Cana&aLs health act inclu&es all the following ecept# ;ni*ersality ortability ublic +&(ission +ccessibility %peciality
210) !f you woul& like to search for (ore infor(ation regar&ing entanyl regulation , youLll In& it in # a) %che&ule 3 in + b) %che&ule ! in 4+<+ c) C%+ %che&ules 211) a) b) c) &) e)
Where can you In& infor(ationLs about (e&ication outsi&e Cana&a? .artin&ale C% +3% Therapeutic Choices atient %elf Care
212) Where can you In& the (onograph of a &rug in Cana&a? a) Co(pen&iu( of patient self care pro&ucts b) Therapeutic choice for .inor +li(ents c) Cana&a &rug &atabase January, 2015
age 2: >f -0
January, 2015 @4F$# 4o C% a(ong the choices) 21') Who publish C+<4 @Cana&ian +&*erse TC &) + new anti arrhyth(ic prescription &rug 215) a) b) c) &)
The (ost epensi*e $ur&en on Cana&aOs health insurance# ental >utpatient (e&ication hysician fees 3ospitaliBation
21) + phar(acist want to increase his phar(acy sales , he can &o all 7cept # a) .ake &iscount for prescription ca(e fro( local physician b) .ake arrange(ent with nurse to (ake regular bloo& glucose (onitor 21) + phar(acist want to (ake an oEer for patients who &onLt co*er with pro*ince insurance , %o he (akes it un&er the na(e of &iscount , he &i& 10 cases &uring a (onth , when he calculate it he foun& that # a) !ncrease net proIt b) ecrease net proIt 21:) a) b) c) &) e)
The key sy(pto( of nephrosis# glucose in urine protein in urine %tone in ki&ney !ncrease in urination freuency (inerals in urine
21) !ncrease the risk of blee&ing (ay occur when co(bining clarithro(ycin with # a) +spirin b) Clopi&ogrel c) ipyri&a(ole &) Warfarin e) 3eparin 220) Carbohy&rates store& in the ani(al cells in the for( of # a) 9lycogen b) 9lucose c) actose 221)
%peciIcity (eans #
January, 2015
age 2 >f -0
January, 2015 a) To ha*e negati*e results with people who &onLt ha*e the &isease b) To ha*e positi*e results with people who ha*e the &isease 222) %ensiti*ity (eans # a) To ha*e repro&ucible results 22') a) b) c) &)
The si(plest for( of (o&ern co((unity phar(acy is #@ Check ) %ole proprietorship artnership !ncorporations ranchise
22-) !n an eperi(ent want to know the nu(ber of newly prescribe& >yco&one an& reIll prescription was un&ergo un&er - physicians what is the na(e of the use& test? a) Chi6%uare b) Wilcoon 225) + prescription for co&eine 9i*e 0, ! tab bi& '0 &ays, < P 1F !s this prescription accepte&? a) 4o, because reIlls are not allowe& b) 4o, because part Ill are not allowe& c) Nes, because the total a(ount is clear &) Nes, because the a(ount is easily i&entiIable 22) Which of the following state(ent is of the responsibilities of a regular authoriBe& phar(acy technician? a) 9i*e a counsel for an >TC (e&ication b) 9i*e a counsel for a new prescription c)
age '0 >f -0
January, 2015 b) +lopecia c) Ai&ney stones &) yskinesia 2'0) a) b) c) &) e)
The (ain screening test for colorectal cancers is # $loo& tests ;ltrasoun& scans test ap s(ear ecal occult bloo&
2'1) !n or&er to protect protein when freeBe &rying which shoul& be a&&# a) 3u(ectant b) rotectant c) yoprotectant 2'2) a) b) c) &)
oly*inyl alcohol is use& in ophthal(ic preparations as # /iscosity 7nhancer %olubilising agent reser*ati*e ubricant
2'') + person ca(e to the phar(acy asking for .arihuana to treat his inso(nia, what is the (ost appropriate action? a) +&*ise hi( to (ake application in special access progra( in health Cana&a b) Tell hi( itLs not allowe& to use .arihuana in Cana&a c) Tell hi( that .arihuana is not in&icate& to treat inso(nia an& a&*ise hi( for a suitable treat(ent 2'-) What is (eant by proItability? a) To co*er the costs with a little re*enue for the owner 2'5) a) b) c) &) e)
What is true about phase !! trials? one on ani(als one on s(all healthy hu(an population to test the safety one on s(all &isease hu(an population to test the eHcacy one on large &isease hu(an population to test the eHcacy an& safety one while the (e&ication in the real worl&
2') a) b) c) &) e)
What is true about phase !!! trials? one on ani(als one on s(all healthy hu(an population to test the safety one on s(all &isease hu(an population to test the eHcacy one on large &isease hu(an population to test the eHcacy an& safety one while the (e&ication in the real worl&
2') Which is not a co(ponent of phar(acy6econo(ics? a) !nternational January, 2015
age '1 >f -0
January, 2015 b) ayer c) 3ospital &) %ociety 2':) a) b) c) &) e)
>; (eans #
2') What is true about aralla error? a) osition of eye at all *olu(etric *essels (ust be at the sa(e le*el as the (eniscus 2-0) a) b) c) &)
Which of the following (e&ications cause KT prolongation? lourouinolones +(oicillin igoin 4itrates
2-1) ysphonia is an i(pair(ent in # a) Taste b) /oice c) %(ell 2-2) a) b) c) &)
When a &rug circulating in bloo& D highly perfuse organs, we na(e it Central Co(part(ent eripheral Co(part(ent 26 Co(part(ent .ulti Co(part(ent
2-') the presence of alternating resi&ues of S6@1, -) linke& 46acetyl glucosa(ine an& 46acetyl(ura(ic aci& is foun& in# a) las(a (e(brane b) Cell wall c) Cytoplas( &) .itochon&ria 2--) When you take the Weight, age an& &isease& state of patients, this is co(paring? a) %tatistical *ariable b) $iological *ariable c) Collecti*e *ariable 2-5) !n your phar(acy a technician (a&e a (istake an& ga*e a wrong (e&ication to the patient, when you notice that (istake you calle& the patient an& you knew that he &i&nLt take his &ose, what is the net step? January, 2015
age '2 >f -0
January, 2015 a)
$isphosphonate (echanis( of action# !nhibit osteoclast resorption !nhibit osteoblast resorption ecrease Ca eecration !ncrease Ca absorption
250) a) b) c) &)
Which of the following is a hu(anistic outco(e# &ecrease patient *isits to physician atient satisfaction ecrease in the $loo& pressure of the patient ecrease in $loo& 9lucose le*el of the patient
251) What is the (ini(u( uantity that can be weight on a balance with sensiti*ity reuire(ents of 15 (g of a 5 Q error is per(issible? a) '00 (g b) 00 (g c) 00 (g
January, 2015
age '' >f -0
January, 2015 252) !n a hospital phar(acy, a patient suEers fro( si&e eEects of a (e&ication an& you foun& that the nurse ga*e hi( a wrong &ose of his (e&ication, what is the (ost appropriate action? a) Try to co*er her (istake b)
Counselling for patient taking /!.>/> @naproen U eso(epraBol) rink a lot =ui&s onOt take antaci& while take *i(o*o Take *i(o*o at least '0 (inutes after (eal Take *i(o*o at least '0 (inutes before (eal /i(ono shoul& be taken with (ilk +ll can be &one to an ankle in"ury ecept?
25) Which of these treat +lBhei(erOs &isease? a) $ro(ocriptine b) $enBtropine c)
25:) %tructure of 4+K! an& itLs a (etabolite of # a) +ceta(inophen 25)
This is#
January, 2015
age '- >f -0
January, 2015
a) b) c) &) e)
%ulfaceta(i&e +cetaBola(i&e urose(i&e 3y&rochlorothiaBi&e %pironolactone
20) What is the (echanis( of action of >rlistat? a) !nhibit gastric ipase 21) a) b) c) &)
What is the use of egg6yolk? 7(ulsifying agent 3u(ectant %uspen&ing agent ubricant
22) What is the enBy(e na(e that foun& in *iruses that enables the( to be release& fro( the host cell? a) 4eura(ini&ase 2') a) b) c) &) e)
Two &rugs with eui*alent therapeutic eEects are best co(pare& by# Cost6$eneIt +nalysis Cost67Eecti*eness +nalysis Cost6.ini(iBation +nalysis Cost6;tility +nalysis Willingness To ay
2-) a) b) c) 25) a)
What is the (echanis( of action of %enna as aati*e? %ti(ulate the bowel wall to contract +llow the stool to pass easier through the bowel !ncrease the bulk of the stool which sti(ulate peristalsis .isoprostol is an ea(ple of # 7icosanoi&s
2) What is the (ost appropriate a&*ice to a patient will start e*othyroin? @ Check ) a) Talk it in the (orning to a*oi& inso(nia b) eeling palpitation is an in&icator of o*er&ose 2) The process by which the *irus transfer 4+ fro( one bacteria to another is calle& # a) Trans&uction b) Translation c) Transfor(ation &) Transportation January, 2015
age '5 >f -0
January, 2015 2:) When a phar(aceutical co(pany starts a research for a new (e&ication, it has to protect her rights by (aking registration for # a) ogo b) Copy
< for a (e&ication as follow # %tart F5 (g then 2F5(g $! for 1- &ays Calculate the &ispense& a(ount? a) F5 (g b) 2F5 (g c) 5 (g
22) + pro&uct with T1G2 >ne year, Concentration -00 (g what will be the concentration after ' years? a) 50 (g b) 100 (g c) 150 (g 2') + patient who is ' years ol& eperiencing sore throatF 3is rF prescribe& for hi( # < 8ithro(a 200 (g 1K for 5 ays !n your phar(acy you ha*e 2 bottles of aBithro(ycin suspension 00 (g @200(gG5(l) D 00 (g @200(gG5(l)F What is the best bottle to be &ispense& to Ill this prescription? a) >ne $ottle of aBithro(ycin 00 (g @ 200(gG5(l ) January, 2015
age ' >f -0
