LAMPIRAN
Gambar 1. struktur proteoglikan
Gambar 2. Syndecan
Gambar 3. Agreccan
Gambar 4. Matriks ekstrasel
Gambar 5. Proteoglikan membran dasar
Gambar 6. Struktur perlekan
Gambar . Struktur agrin
Gambar !. Struktur bamakan
Gambar ". Proteoglikan #enis $yalektan
Gambar 1%. Struktur &ersikan
Gambar 11. Struktur agrekan
Gambar 12. Struktur neurokan
Gambar 13. Struktur bre&ikan
Gambar 14. Proteoglikan #enis S'(Ps )Small 'eucine*(ic$ Proteoglycans+
Gambar 15. Struktur S'(Ps )Small 'eucine*(ic$ Proteoglycans+
Gambar 16. Struktur glukosamin
Gambar 1. ,alur pembentukkan $eksosamin
Gambar 1!. ,alur sintesis glukosamin dan turunannya
Gambar 1". Stuktur kondroitin
Gambar 2%. Pembentukkan prekursor gula nukleotida
Gambar 21. Pembentukkan kondroitin
Gambar 22. Perbedaan tulang )A+ dan tulang ra-an )+
Gambar 23. /omponen tulang ra-an pada sendi
Gambar 24. Penyakit osteoartritis
Gambar 25. 0katan *glikosidat antara GalAc dan Ser
Gambar 26. 0katan *glukosamin antara GlcAc dan nitrogen amida pada Asn
Gambar 2. ,alur sintesis untuk pembentukan P*Gula dan PAPs
Gambar 2!. (ingkasan struktur glikosaminoglikan dan pelekatanya pada protein inti
Gambar 2". Siat tama Glikosaminoglikan
Gambar 3%. Struktur Asam ialuronat
Gambar 31. Asam ialuronat ditulang dan tulang ra-an )/artilago+
Gambar 32. Asam ialuronat di dalam mata
Gambar33. Asam ialuronat di dalam kulit
Gambar 34. iosynt$esis yaluronat
Gambar 35. Skema degradasi A
Gambar 36. Perbedaan biosintesis $eparin sulat7 kondroitin sulat atau glikosaminoglikan dermatan sulat.
Gambar 3. iosintesis eparin8eparan sulat
Gambar 3!. egradasi $eparin8$eparan sulat
Gambar 3". Perbedaan disakarida dermatan sulat
Gambar 4%. egradasi dermatan sulat
Gambar 41. Gambaran ungsi 0doA pada S89S. )A+ peran 0doA pada penyimpanan sitokin gro-t$ actor7 )+ orreliainection7 )9+ at$erosclerosis7 )+ koagulasi7 ):+ P*selectin*dependent leukocyte recruitment7 );+ pengaktian sitokin dan reseptor gro-t$ actor7 dan )G+ pengara$an leukosit ole$ 09AM.
Gambar 42. Struktur /eratan Sulat
Gambar 43. /eratan Sulat 0
Gambar 44. /eratan Sulat 00
DAFTAR PUSTAKA
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