A34y e arol dwomanpr es ent st ohergener al ph y s i c i anwi t hnons pec i fi cf e v er offi veday s' dur at i on.Shes ay st hatt her ear es wol l en" bumps "i nherr i ght ax i l l ar yr egi onwhi c har epai nf ul .Shec ompl ai nsoff at i gue,l owgr adef ev er , ands omes t omac hpai n.Ph ys i c al e x am r e v eal st enderr i ghtax i l l ar y l y mphadenopat mp h y .Sheal s ohasami norl ac er at i ononherr i ghtf or ear mt hat herc atga v eheraweekago.Sheadmi t st oa5k gwei ghtl os s ,buts a y ss hei s nothungr y . Whatfi ndi ngsar el i k el yt obepr omi nenti fabi ops ywasper f or med ofar i ghtax i l l ar yl y mphnode? mp A.Pr omi nentger mi nal c ent er s B.Eff ac ementoft henodal ar c hi t ec t ur e C.Pr ol i f er at i onofc y t ot ox i cCD8Tc el l s D.At y pi c al l y mphoc mp yt es E.Nu me me r o usb an dc e l l s ec or r ec tans weri sE Thi spat i enti smos tl i k el ys uffer i ngf r om " c at s cr at c hdi s eas e" ,abac t er i al i nf ec t i onc aus edbyBar t onel l ahens el ae.Thi suni l at er al l y mphadenopat mp hyon t hes i deoft hes cr at c hc ombi nedwi t hnons pec i fi ccons t i t ut i onal s ympt omsi s c har ac t er i s t i coft hedi s eas e.Thepat i entt husl i k el yhasex pans i onofger mi nal c ent er s ,whi c har eaggr egat esofBc el l st hatc anoc c uruponant i gen pr es ent at i on. Effac ementofnodal ar c hi t ec t ur ei schar ac t er i s t i cofl y mphoma, mp es pec i al l yHodgki nl ymphoma mai naf emal epat i entoft hi sage. Pr ol i f er at i onofc yt ot ox i cCD8Tc el l scanoc curdur i ngadel ay ed hy per s ens i t i v i t yr eac t i ont oant i genssuc hast uber c ul os i s . At y pi c al l y mphoc y t esar ec har ac t er i s t i ct oi nf ec t i onwi t hEbs t ei nBar rVi r usor
c yt omegal ov i r us . Nume r o usban dc e l l sar emor ec o mmoni na c ut es e pt i ci n f e c t i o nss uc has t h o s
2.A41y ear ol dwomanwi t hnos i gni fi c antmedi c al hi s t or ypr es ent s c ompl ai ni ngoff at i gueandl i ght headednes s .Phy s i c al e xam i snot abl ef or c onj unc t i v al pal l or ,bi l at er al br i s kpat el l arr efl ex es ,s l i ght l yat ax i cgai t ,and i mpai r edpos i t i onandv i br at i ons ens ei nt hef eetbi l at er al l y .Herhemat oc r i ti s 23%.Ser ol ogi cst udi esar epos i t i v ef orant i par i et al c el l ant i bodi es .What woul dy ouex pec tt oseeonper i pher al bl oodsmear ? A.Bur rc el l s B.Hy p er s e gme nt e dn eu t r o phi l s C.Howel l J ol l ybodi es D.Sc hi s t oc yt es E.Spurc el l s Goo dWor k Thec or r ec tans weri sB Thi spat i enthasper ni c i ousanemi a ,aut oi mmuneat t ac konpar i et al c el l s c aus i ngdec r eas edpr oduc t i onofi nt r i ns i cf ac t orandr es ul t antv i t ami nB12 defi c i enc y .B12defi c i enc yc aus esameg al obl as t i canemi a( wi t h hy per s egment edneut r ophi l sonbl oods mear ) ,s t omat i t i s ,gl os si t i s ,and s ubac ut ecombi neddegener at i onofper i pher al ner v esandspi nal c or d( whi c h c anc aus eat ax i a,hy per r efl ex i a,andi mpai r edpos i t i on/ v i br at i ons ens e) .Bur r c el l s( A)ands purc el l s( E)ar et y pesof poi k i l oc y t es -bur rc el l ssugges tr enal di s eas eands purc el l s( ac ant hoc yt es )s ugges tl i v erdi s eas eorl i pi d abnor mal i t i es . Howel l J ol l ybodi es ( C)ar ec l us t er sofDNAwi t hi nRBC c yt opl as mi ndi c at i v eofas pl eni aorhy pos pl eni a. Sc hi s t oc yt es ( D)ar e
f r agment edr edbl oodc el l st hatar es eeni nmi c r oangi opat hi cdi s eas essuc h asdi s s emi nat edi nt r av as c ul arc oagul at i on( DI C) ,t hr ombot i ct hr omboc yt openi c p ur pur a( TTP) ,an dhe mol y t i cu r e mi cs y n dr ome( HUS) . 3. A45y ear ol dmanwi t hahi s t or yofal c ohol i s m dev el opspanc r eat i t i s .What
pat hol ogi cchangeswoul dl i k el ybes eeni nt hi spat i ent ' spanc r eas ? A.Eos i nophi l i cdepos i t si nv as cul arwal l s B.Gr anul omat ousi nfl ammat i onwi t hs omepr es er v a t i onoft i s s ue ar c hi t ec t ur e C.Li quefi ednec r ot i ct i s sue D.Nec r ot i cf atc el l s ,c al c i um s oapf or mat i on,andl i pi dl adenmac r ophages E.Ti s suear c hi t ec t ur ewel l pr es er v ed,wi t hnuc l earc hanges
Thec or r ec tans weri sD Check It!
En z y ma t i cf atnec r os i s i sseeni npanc r eat i t i s ,andi schar ac t er i z ed hi s t ol ogi c al l ybynec r ot i cf atc el l s ,c al c i um s oapf or mat i on,andl i pi dl aden mac r ophages .Thet womos tf r equentc aus esofpanc r eat i t i s a r egal l s t onesandal c ohol . Eos i nophi l i cdepos i t si nv as cul arwal l si sr epr es ent at i v eof fi br i noi dnec r os i s . Gr anul omat ousi nfl ammat i onwi t hs omepr es er v at i onoft i s s uear c hi t ec t ur ei s r epr es ent at i v eof c as eousn ec r os i s .Li quefi ednec r ot i ct i s s uei sr epr es ent at i v e ofl i quef ac t i v enec r os i s .Ti s suear c hi t ec t ur ewel l pr es er v ed,wi t hnuc l ear c hangesi sr epr es ent at i v eof c oagul at i v enec r os i s .
4 .A4 5y e ar o l dma nc a nno tl ea v eh omewi t h ou ta nt ac i d sbe c au s eh eh as hads ev er ehear t bur nwi t hev er ymeal f or10y ear s .Whi c hoft hef ol l owi ngi s l i k el yt obes eenonbi ops yofhi sl oweres ophagus ? A.Co l umn arme t a pl as i a B.Hy per pl as i a C.Hy per t r oph y D.Nor mal es ophageal epi t hel i um E.Squamousmet apl asi a
Thec or r ec tans weri sA Bar r et t ' ses ophagusi sac ompl i c at i onof gas t r oes ophageal r efl ux di s eas e ( GERD) .Thel o wer2 / 3oft hees ophagusi sc ompos edofs t r a t i fi ed s quamousepi t hel i um.Wi t hr epeat edex pos ur et oc aus t i cgas t i cac i d,t i s suei n t hel oweres ophagusi sr epl ac edwi t hc ol umnargl andul arepi t hel i um wi t h gobl etc el l sr es embl i nggl andul arc el l soft hei nt es t i nest hats ec r et emuc i n. Thi spr oc es si scal l edmet apl as i a,i nt hi scas ecol umnar . Hy per pl as i ai sani nc r eas ei nt henumberofc el l si nat i s suer egi on,s uc has endomet r i al hy per pl as i a.Hy per t r ophydes cr i besenl ar gementofex i s t i ngc el l s , s uc hasi nhy per t r ophi cc a r di omy o pat h y .Squamousme t apl as i awoul dno t o c c uri nt h ee s op ha gus ,wh er eep i t he l i um i sn or ma l l ys q ua mo us .Sq uamo us met apl as i ac anoc curi nt hebl adder ,c er v i x ,orl ungs .
5.A46y ear ol dwhi t emal ewi t haf ami l yhi s t or yofes ophageal a den oc ar c i no map r e s ent sc omp l ai n i ngo fhe ar t bu r n .One nd os c op y ,a c r es c ent s hapedar eaofer y t hemat ousmuc os ai ss eent hate x t endsa bo v et he
gas t r oes ophageal j unc t i on.Abi ops yoft hi sar eaofmuc os ai st ak en.What hi s t ol ogi c al f eat ur eswi l l mos tl i k el ybes eenonH&Es t a i n ? A.Col umnarepi t hel i um wi t hgobl etc el l s B.Col umnarepi t hel i um wi t hpar i et al c el l s C.Ker at i ni z edsquamousepi t hel i um D.Nonk er at i ni z eds quamousepi t hel i um E.T r ans i t i onal epi t hel i um Thec or r ec tans weri sA Thi ser y t hemat ousmuc os ai sl i k el yBar r et t ' s esophagus ,ormet apl as i aoft henor mal s quamousepi t hel i um oft hedi s t al es ophagust oc ol umnarepi t hel i um.Thi sus ual l yoc cur si nt hes et t i ngof gas t r oes ophageal r efl ux .Bar r et t ' si sc ons i der edpr emal i gnantf ores ophageal adenoc ar c i noma,butnotf ors quamousc el l c ar c i noma.Gobl e tc el l sar e muc ous s ec r et i ngc el l st hatwi l l eas i l ybes eeni nBar r et t ' sonH&Es t ai n. Par i et al c el l sar enotas soc i at edwi t ht hedev el opmentofBar r et t ' sf ur t her mor e,t heywoul dnoteas i l ybes eenonH&Es t ai n.T r ans i t i onal epi t hel i um i ss eeni nt heur i nar yt r ac t . 6,BASI CS CI ENCE :HI S T OL OGY A65y ear ol dmanwi t hnopas tmedi c al hi s t or ypr es ent sf orhi sannual c hec k up.Heno t ess omei nc r eas eddy s pneaone x er t i onal ongwi t hano v er al l l et har gi cf eel i ngf ort hepas tf ewmont hs .Phy si c al ex am i snor mal wi t ht he ex c ept i onofahemeoc cul tpos i t i v es t ool t es t ,andhei ssubs equent l yf oundt o hav eel ev at edl i v erf unc t i ont es t s .Whi c hoft hef ol l owi ngi st r ue? A.Aper i pher al bl oods mearwi l l s howmi c r oc y t i cer y t hr oc yt es B.ACEAl ev el wi l l beatl eas tt wi c et heupperl i mi tofnor mal C.Aper i pher al bl oods mearwoul ds ho w pol y mor phonuc l earc el l swi t h mor et hanfi v el obesoft henuc l eu s
D.Abi ops yoft hepr i mar yl es i onwi l l s hows i gnet r i ngc el l s E.ACEAl ev el wi l l beundet ec t abl e
BASI CS CI E NCE :HI S T OL OGY
A65y ear ol dmanwi t hnopas tmedi c al hi s t or ypr es ent sf orhi sannual c hec k up.Heno t ess omei nc r eas eddy s pneaone x er t i onal ongwi t hano v er al l l et har gi cf eel i ngf ort hepas tf ewmont hs .Phy si c al ex am i snor mal wi t ht he ex c ept i onofahemeoc cul tpos i t i v es t ool t es t ,andhei ssubs equent l yf oundt o hav eel ev at edl i v erf unc t i ont es t s .Whi c hoft hef ol l owi ngi st r ue? A.Aper i pher al bl oods mearwi l l s howmi c r oc y t i cer y t hr oc yt es B.ACEAl ev el wi l l beatl eas tt wi c et heupperl i mi tofnor mal C.Aper i pher al bl oods mearwoul ds ho w pol y mor phonuc l earc el l swi t h mor et hanfi v el obesoft henuc l eu s D.Abi ops yoft hepr i mar yl es i onwi l l s hows i gnet r i ngc el l s E.ACEAl ev el wi l l beundet ec t abl e
8. A65y ear ol dmanpr es ent swi t hwor s eni ngs y mpt omsofdi ffic ul t yr i s i ng
f r om ac hai r ,s huffli nggai t ,dr ool i ng,t r emoratr es t ,andc ons t i pat i on.Whi c hof t hef ol l owi ngi st hemos tl i k el yfindi ngonex ami nat i onoft i s suei fabr ai nbi ops y wasper f or med? A.Amy l oi dneur i t i cpl aquesi nneoc or t ex B.At y pi c al l y mphoc y t es C.Eos i nophi l i cspher es hapedi nc l us i onsi nc yt opl as m
D.Neur ofi br i l l ar yt angl eswi t hi nneur ons E.Pr ot ei naggr egat i onsandi nt r anuc l eari nc l us i ons
Check It!
Thec or r ec tans weri sC -eos i nophi l i cspher es hapedi nc l us i onsi nc y t opl as m.Thes ear eLewy bodi es andt heyar et hepat hol ogi c al hal l mar kofPar k i ns on' sdi s eas eal ong wi t hdegener at i onofdopami ner gi cneur onsoft hes ubs t ant i ani gr a.I ti s i mpor t antt ofi r s tr ec ogni z et hatt hi spat i ent ' ssy mpt omsar es eeni n Par k i ns on' sdi s eas e. Theot herhi s t ol ogi c al fi ndi ngsar es eeni not herneur ol ogi c al di s eas es . Amy l oi dneur i t i cpl aquesandneur ofi br i l l ar yt angl esar es eeni nAl z hei mer ' s di s eas e.At y pi c al l y mphoc yt esma ybes eeni nav i r al enc ephal i t i ss ec ondar y t oEps t ei nBar rVi r usi nf ec t i on.Pr ot ei naggr egat i onsandi nt r anuc l ear i nc l us i onsar efi ndi ngsi nHunt i ngt on' sChor ea. 10.Afi v emont hol di nf anti sbr oughtt oy ouroffic ewi t hadi s t r es sedmot her . Sh ec o mp l a i nst h athebr ui s e sea s i l ywh enonhi sb ac ka ndar mswh enhei s l ai di nhi sc r i bev er yni ght .Shet hi nk shi sj oi nt sf eel " l oos e"andt hatwhens he pi c k shi m ups hei saf r ai dt hats hema ydi s l oc at ehi sshoul der s .One x am hi s ar msf eat ur eec c hy mos esandc i gar et t epaper l i k es t r et c hmar k sont hes k i n. Whi c hoft hef ol l owi ngi st hel i k el ydef ec tc aus i ngt hi si nf ant ' spr es ent at i on? A.Defi c i enc yofs phi ngomy e l i nas e B.Dy n ei nar md ef e c t C.Faul t ycol l agens ynt hes i sandmi s f ol di ng
D.Fi br i l l i ngenemut at i on E.Gl y c ogenac c umul at i oni nmus c l et i s s ue
Thec or r ec tans weri sC Thi si nf anti sex hi bi t i ngac l as s i c al f or m of Eh l er s Da nl oss y n dr ome , c har ac t er i z edbyhy per ex t ens i bl ej oi nt sands ki nunderphy si ol ogi cl oadi ng, andat endenc yt obl eed,duet oadef ec ti nc ol l agens y nt hes i sandf ol di ng. Sphi ngomy e l i nas edefi c i enc yi sas s oc i at edwi t hNi emannPi c kdi s eas e. Ady nei nar m def ec tr es ul t i ngi ni mmot i l ec i l i ai sf oundi nKar t agener ' s syndr ome. Theaut os omal domi nantfi br i l l i ngenemut at i oni sf oundMar f an' sdi s eas e. Gl y c ogenac c umul at i oni nt hemus c l et i s s ueofi nf ant sandt oddl er scanbe v er i fi edmi c r os copi c al l yi nMc Ar dl e' sdi s eas e,adi s or derofgl y cogens t or age. 11.
Apat hol ogi s ti sper f or mi nganaut ops yont hebr ai nofa42y ear ol d
womanwhodi edi nt hesamewayherf at herandgr andmot herhadwhi ch i nc l udedapr ol ongedc our s eo fdement i a,unc ont r ol l edl i mbmo v ement s ,and moodc hanges .Whati st hepat hol ogi s tmos tl i k el yt ofi ndonaut ops y ? A.Cor t i c al amy l oi dpl aques B.Li ghtc ol or eds us bt ant i ani gr a C.Mul t i pl ei s chemi cl es i ons D.Shr u nk e nh eadoft hec aud at e E.Vac uol esandgl i os i s
Thec or r ec tans weri sD Theage,genet i cpat t er nands y mpt omsi nt hev i gnet t es ugges tt hatt he pat i entdes cr i bedl i k el ys uffer edf r omHunt i ngt on' sd i s eas e.Thepat hol ogi c al fi ndi ngsc har ac t er i s t i cofHunt i ngt on' si nc l udeas hr unk enheadoft hec audat e ( c hoi c eD)anddi l at edv ent r i c l es . Cor t i c al amy l oi dpl aques( Choi c eA)ar et y pi c al fi ndi ngsofAl z hei mer ' s di s eas e,butwoul dbeunl i k el yi na42y earol danddoesnotf ol l owac l ear genet i cpat t er n. Li ghtc ol or eds us bt ant i ani gr a( c hoi c eB)ar ec l as si cfi ndi ngsi nPar k i ns on' s di s eas e,wher eal os sofdopami ner gi cneur onsoc cur s .Par k i ns on' si sunl i k el y t oc aus edement i ai nsuc hay oungpat i ent . Mul t i pl ei s c hemi cl es i ons( Choi c eC)ar ec har ac t er i s t i cofmul t i i nf ar c t d eme nt i a ,wh i c hwo ul db eu nu s ua li nawo ma no f4 2. Vac uol esandgl i os i s( c hoi c eE)ar et y pi c al fi ndi ngsi nCr eut z f el dt J ak ob Di s eas e,whi c hi sgener al l ynotagenet i cdi s eas e. 12.Apat hol ogi s tr ec ei v esanor mal s pec i menr es ec t edf r om apat i ent ' s gas t r oi nt es t i nal t r ac t .Undert hemi c r os cope,s hes eest hatt hemuc os a c ont ai nscol umnarc el l sl ac ki ngv i l l i .Ther ear emanyst r ai ghtandl ongt ubul ar gl ands .Thi ss pec i menmos tl i k el yor i gi nat esf r om whi c hpor t i onoft heGI t r ac t ? A.Esophagus B.Lar gei nt es t i ne C.Phar ynx
D.Smal l I nt es t i ne E.St omach
hec or r ec tans weri sB Thel ar gei nt es t i ne( c hoi c eB)c ont ai nst hec ec um andt hec ol on.I t smuc os ai s c ompos edofc ol umnarc el l sl ac ki ngv i l l i ,andc ont ai nsopeni ngswhi c hgi v e wa yt ot ubul argl andsk nownast hec r y pt sofLi eber k uhn . Themuc os aoft hees ophagus( c hoi c eA)i sc ompos edoft hi c k ,s t r at i fi ed, s quamous ,nonk er at i ni z edepi t hel i um. Thephar y nx( c hoi c eC)c ont ai nsst r at i fi ed,s quamousepi t hel i um,aswel l as c i l i at ed,ps eudos t r at i fi ed,c ol umnarepi t hel i um. I nt es t i nal v i l l i ar et hehal l mar koft hes mal l i nt es t i ne( c hoi c eD) .Theyar e c o mp os e do fo ut g r o wt h soft h emu c ou sme mb r a nei n t ot h el u me n.Cr y p t so f Li eber k uhnar eal s of oundi nt hes mal l i nt es t i ne. Thes t omac h( c hoi c eE)muc os ac ont ai ns i mpl e,c ol umnarc el l s ,butl ac k st he c r y pt sofLi eber k uhn.
13.
Aphy si c i ans ci ent i s ti sc onduc t i nganex per i menti nwhi c hs het r i est o
s t i mul at egr owt hofc ar t i l agei nv i t r o.Shewi s hest ous eas ubs t anc et o s t i mul at ehi s t ogenes i s .Whi c hs ubs t anc ewoul dbebes ts ui t edt oherpur pos es bas edoni t ss t i mul at i onofc ar t i l agegr owt hi nv i v o? A.Cor t i s one B.Es t r ogen
C.Th yr o xi ne D.Vi t ami nA E.Vi t ami nD
Thec or r ec tans weri sC Car t i l agegr owt hi ss t i mul at edbyt hy r ox i ne( Choi c eC) ,t es t os t er oneand g r o wt hho r mo ne . I ti si nhi bi t edbyes t r ogen( Choi c eB)andc or t i s one( Choi c eA) . Vi t ami nA( Choi c eD)andVi t ami nD( Choi c eE)ar ei n v ol v edi nbone mi ner al i z at i on. 14.Ani nf anti sbor npr emat ur el yat32week si nr es pi r at or ydi s t r es s.Ac hes t Xr a ys howss i gnsofneonat al r es pi r at or ydi s t r es ss yndr ome( RDS)andt he i nf anti st r eat edwi t hex ogenoussur f ac t ant .Whi c hoft hef ol l owi ngt y pesof pul monar yc el l smak ess ur f ac t ant ? A.T y peIal v eol arc el l s B.T y peI Ial v eol arc el l s C.Capi l l ar yendot hel i al c el l s D.Cl ar ac el l s E.Ps eudoc ol umnarc i l i at edc el l s
Sur f ac t anti smadeb yt y peI Ial v eol arc el l s ands t or edi nl amel l arbodi eswi t hi n t hes ec el l s .Theyst ar tdev el opi ngaf t er24week sges t at i on,whi c hi soneof t hemaj orr eas onsbi r t hbef or e24week si snotc ompat i bl ewi t hl i f e.T ypeI al v eol arc el l smak eupt hemaj or i t yoft heal v eol ars ur f ac e.Capi l l ar y
endot hel i al c el l ss ec r et eangi ot ens i nc onv er t i ngenz yme( ACE) .Cl ar ac el l sar e mos t l yf oundi nt hepr i mar ybr onc hi ol esandc ont ai nP450enz y mest ode t o xi f y har mf ul c hemi c al si nt hel ungs .Ps eudoc ol umnarc i l i at edc el l sl i net het r ac hea, c r eat i nga" muc oc i l i ar yes cal at or "t oex pel t ox i ns / dus ti nt heupperai r way s.
1.Ano t her wi s eheal t h yKen y anmani spr es c r i bedt r i me t hopr i ms ul f amet hox az ol ef oraur i nar yt r ac ti nf ec t i on.Hepr es ent st ot he emer genc ydepar t mentwi t hj aundi c e,f at i gue,andc onf us i on.Whi c hof t hef ol l owi ngmi ghty ous eei nt heRBCsofaper i pher al s mear ? 2. A.Hei nzbod i es B.Howel l J ol l ybodi es C.Bas ophi l i cs t i ppl i ng D.Au err o ds E.Reeds t er nber gbodi es
Thec or r ec tans weri sA G6PDdefic i ency i sof t enas ympt omat i cunt i l f ac edwi t hanox i dat i v e c hal l enge,s uc hast hedr ugTMPSMX.I tus ual l yoc c ur si npeopl eofc ent r al Af r i c an,Mi ddl eEas t er n,orWes t er nAs i anor i gi n.Thec l as si cfindi ngi nRBCs i sHei nzbodi es( Ans werA) ,whi c har ec ol l ec t i onsofdenat ur edhemogl obi n. Howel l J ol l ybodi esar enuc l earr emnant si nRBCst hatr emai nduet of ai l ur eof s pl eni cseques t r at i oni nSi c k l ec el l di s eas e.Bas ophi l i cs t i ppl i ngr epr es ent s RNAc ol l ec t i onst hatar emos tc l as si c al l yas s oc i at edwi t hl eadpoi s oni ng.Auer r odsar ec l umpsofgr anul armat er i al di agnos t i cofac ut emy el oi dl euk emi a ( AML) .Reeds t er nber gbodi esar et he" o wl e y es "pat hognomoni cf or Hodgki n' sl ymphoma.
16. I ny oungi nf ant saswel l asger i at r i c spat i ent s ," bandemi a"( i nc r eas edband
c el l s )i sas i gnofac ut ebac t er i al i nf ec t i on.Whenabandc el l sdi ffer ent i at es , whi c hoft hef ol l owi ngt y pesofc el l si sapos si bl emat ur ec el l t y pei tc an be c ome? A.Er y t hr oc yt e B.Lymphocyt e C.Neut r ophi l D.Monocy t e E.Pl at el et
hec or r ec tans weri sC My el obl as t sdi ffer ent i at ei nt opr omy el oc yt es ,my el oc yt es ,met amy el oc yt es , t henbandc el l s ,andfi nal l ybr anc hi nt oneut r ophi l s ,eos i nophi l sandbas ophi l s . Thes et y pesofc el l sar eal l k nownasgr anul oc yt es . L y mp ho bl a s t sdi ffer ent i at e i nt oBc el l andTc el l l y mphoc y t es ,aswel l asnat ur al k i l l er c el l s .Mo no bl a s t s d i ffer ent i at ei nt omonoc yt es . Meg ak a r y o bl a s t st ur ni nt o megak ar y oc y t es ,whi c hpr oduc epl at el et s . 17.