PANPACIFIC UNIVERSITY NORTH PHILIPPINES Urdaneta City, Pangasinan
Ascending Cholangitis
CASE STUDY (Tarlac Provincial Hospital)
In Partial Fulfillment of the Requirements For General Case Presentation
Submitted by: Tarlac Group (October Rotation)
October 2009
I. PATIENT ASSESSMENT DATA BASE A.
GENERAL DA DATA
1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 10. 11.
B.
Pati Patien ent t’s Name ame: Pat Patie ient nt XYZ XYZ Addr Addres ess s: Ta Tarla rlac Cit City, y, Tarl arlac Age: 42 y/o Sex: Male Birth Date: May 7, 1968 Rank Rank in the Fami Family ly: : Eldes ldest t Nationality: Fi Filipino Civi Civil l Sta Statu tus: s: Marr Marrie ied d (Wi (Wido dowe wer) r) Date Date of Admi Admiss ssio ion: n: Octo Octobe ber r 3, 3, 200 2009 9 Orde Order r of of Admi Admiss ssio ion: n: 4:04 4:04pm pm Attend Attending ing Physic Physician ian: : Dr. Dr. Roedel Roedel Dizon Dizon
CHIEF COMPLAINT
Patient had fever and complaint of epigastric pain prompting immediately his family members to consult. The client was weak and pale in appearance and noted to have facial grimacing. Patient XYZ has been guarding the affected area, furthermore, cold clammy sweat has been observed.
C.
HIST HISTOR ORY Y OF OF PRE PRESE SENT NT ILLN ILLNES ESS S
Patient’s condition started 1 week prior to admission with epigastric pain with on and off fever. He went to to Cagayan Cagayan Valley Valley Medical Medical Center Center for for consult consult on September with a diagnosis diagnosis of dyspepsia dyspepsia. . After After medical medical intervent interventions, ions, patient was then discharg discharged ed and apparently well. Until few hours prior to admission, patient had fever and complaint of right upper quadrant (RUQ) abdominal pain so they immediately went to Tarlac Provincial
Hospital for consult and was admitted. He has been given medications such as Dobutamine and has had his initial laboratory exams.
D.
PAST PAST HEAL HEALTH TH HIST HISTOR ORY Y/STA /STATU TUS S
Patient had chicken pox, measles and mumps when he was a child. However, he and his watche watcher r could could not remembe remember r how old he was when he got them. He verbal verbalize ized d that that his immunization was complete. When he was in grade one, he had a perforating eye injury that caused the blindness of his right eye. E.
FAMILY ASSESSMENT Name
Relation
Age
Sex
Occupation
Educational Attainment
Sergio Maniti
Father
63
Male
none
3rd Year High School
2nd Year High School Imelda Maniti
Mother
---
Female
---High School graduate
Shiela Bimeda
Sister
41
Female
Government Employee
Graduate of Automotive Vocational Course
4th Year Highschool Ambulance
Sergie Maniti
Brother
39
Male
Driver
High School Graduate High School Graduate
Housewife Shirly Macasiog
Sister
36
Female
Housewife Sharon Tanhueco
Sister
26
Female
Service Crew Shalee Jonnales F.
Sister
26
Female
SYSTEM SYSTEMS S REVIE REVIEW W – GORDO GORDON’S N’S 11 FUNCT FUNCTION IONAL AL HEAL HEALTH TH PATT PATTERN ERNS S ASSES ASSESSME SMENT NT
1.
Health Perception - Health Management Function
Patient XYZ had stated that being healthy is free from sickness and the absence of disease. He refers to doctors whenever he or one of his family members gets sick. sick. He managed managed his health health by following following medical medical treatment treatment being given given by his health health care care provid providers ers. . In additi addition, on, he percei perceived ved that that he is not totall totally y healthy because his right eye has been blind since on the first grade. 2.
Nutr Nutrit itio ion n – Meta Metabo boli lic c Patt Patter ern n
The client eats thrice a day with adequate amount of food. He has good appetite. His usual daily menu includes meat and vegetables. He drinks 12-15 glasses of water and up to 2 cups of coffee a day. 3.
times times a brownish in use laxatives 4.
Elimination Pattern
He urinates 3-4 times a day with amber-colored urine. He further stated that urinating urinating is not a problem. problem. Defecation Defecation pattern pattern has been reported to be seven week week most most occurr occurring ing in the mornin morning g with with a semi-s semi-soli olid d consi consiste stency ncy and color. No difficulty of defecating has been stated and did not have to and other stool softeners. Acti Activi vit ty – Exe Exercis rcise e Pat Patte ter rn
_0_ Feeding _0_ _0_ Bathing _0_ Be Bed Mo Mobility
_0 _ Dressing _0 _ Toileting _0_ Ho Home Ma Maintenance
_0 _ Grooming _0 _ Cooking
Legend: 0 – Full care I – Requires use of equipment II – Requires assistance or supervision from others III- Requires assistance or supervision from another equipment and a device IV – Dependent; doesn’t participate 5.
Cogn Cognit itiv ive e – Perc Percep eptu tual al Patt Patter ern n
Hearing: Visi Vision on: :
No hearing abnormalities as state by the client His His left left eye func functi tion ons s norma normall lly y and does does not not need need to use eyeg eyegla lass sses es when reading. Sensory Perception: No sensory perceptual abnormalities
Learning Styles: He learns upon doing it by himself. Understands more when there are illustrations 6.
Sleep – Rest P Pa attern
He sleeps 6-8 hours a day. He does not need any relaxation techniques for him to fall asleep easily. He does not have any sleeping difficulty. When travelling, would would request request for the vehicle vehicle to stop if it’s already already time for them to sleep. sleep. Approximately, they would sleep up to 5 hours.
they
7.
Self Self-P -Per erce cept ptio ion n And And Self Self-C -Con once cept pt Patt Patter ern n
He does not consider himself as a burden to his Aunt’s family. He even said that he helps in their daily expenses by giving some of his earnings to them. As a patient, patient, he said it’s normal normal that family family members members take care of him especiall especially y he doesn’t doesn’t have a family family of his own. He considers considers himself himself as simple simple and hardworki hardworking ng person. person. At work, he is the one who cooks for the whole whole crew. crew. He said he is good in cooking. He is also a good mechanic though he wasn’t able to learn how to drive. He said, he is too afraid to drive. 8.
Role Role – Re Relati latio onshi nship p Pat Patte ter rn
He is a good brother and a good son to his parents. He had proven being a responsib responsible le family family member member when he decided decided to work immediately immediately for them after from high school. He is in good terms with his Aunt’s family.
graduating
At work, he is a dependable co-worker. He said, whenever a co-worker needs help, he trie tries s to help help him. him. When When conf confli lict ct aris arises es, , he init initia iate tes s to reso resolv lve e it immediately. 9.
Sexu Sexual alit ity y – Repr Reprod oduc ucti tive ve Patt Patter ern n
He said he is still sexually active, though he does not practice safe sex. He admits that he doesn’t want to use condom. He practices withdrawal method. He is of the circumstances of not practicing safe sex but he said it’s a matter of whatever will happen to him like acquiring sexually transmitted infections.
aware fate 10. 10.
Copi Coping ng – Str Stres ess s Tole Tolera ranc nce e Patt Patter ern n
When he has problems, he solves it by himself. He does not bother other family members to help him solve it especially if it is manageable. Sometimes, he drinks alcohol to cope from his problem. 11. 11.
guidance
G.
Valu Value e – Beli Belief ef Patt Patter ern n
He is a Catholic. He would go to church if there is time. He still believes that God would help him to solve his problems. He prays to ask for assistance and especially when they are travelling.
Here Heredo do-Fami Famili lia al Ill Illness ness
Father (TB, HPN)
Patient XYZ (Ascending Cholangitis)
2nd Child
3rd Child
Mother (Diabetes)
4th Child
5th Child
6th Child
7th Child
H.
DEVELOPMENTAL H HI ISTORY Theorist
Erik Erikson’s Psychosocial Theory
Ag e
40 – 65 y/o Generativity vs. Stagnation
James Fowler’s Stages of Faith Development
for both male and female
for both male and female
Conjunctive Faith Stage (mid-life)
I.
Sex
Patient Description
The patient did not have a child of his own. He was not able to fulfill his role as a parent. He wanted to have a child but unfortunately his wife died. He said he had no luck but was contented with his immediate family. It seems that he is being passive and feels lack of purpose and productivity. The patient verbalized that it is better that he had no family so he could work and travel without worrying about them when he’s away. He added that he don’t have future plans to have his own family. I observed that this might be contradictory to what he really wants. He also said that he wanted to have his own child, therefore, it seems he only want to confine himself to the reality that he might not be able to have his own family at this stage of his life.
PHYSICAL ASSESSMENT A. General Survey
Oxygen
Patient XYZ was was awake, lying on bed, conscious conscious and coherent, coherent, and weak in appear appearanc ance. e. A nasoga nasogastr stric ic tube tube was insert inserted ed at the right right nares nares asepti aseptical cally. ly. inhalation was given regulated @ 3 LPM. An IVF of D sW + 2 ampules of
Dobutamin Dobutamine e was connecting to a
infused infused at his right hand as venoclis venoclisis. is. An IFC has been inserted inserted urine bag inplace.
B. Vital Signs 1st Day
BP: T : RR: CR:
110/80 mm Hg 39.6 °C 32 bpm 100 bpm
2nd Day
3rd Day
120/80 mm Hg 37.8 °C 30 bpm 98 bpm
110/90 mm Hg 37.7 °C 28 bpm 95 bpm
C. Regional Exams
Area Assessed
Techniques Used
Findings
Skin
> color
inspection
> texture > temperature > moisture
palpation palpation palpation
dark-skinned with hyperpigmentations rough and dry warm to touch dry
inspection palpation inspection inspection
pink, not clean slightly rough convex curvature firm
Nails
> > > >
color of nailbed texture shape nail base
Hair
> > > >
color distribution moisture texture
inspection inspection inspection inspection
black evenly distributed oily fine
> eyebrows
inspection
> eyelashes > ability to blink
inspection inspection
> ocular movement > sclera > pupils
inspection inspection inspection
symmetrically aligned, equal movement slightly straight blinks voluntarily eyes move freely (both) icteric (jaundice) round, reactive to light, constricts briefly (L eye)
Eyes
Nose
> symmetry, shape, size and color > mucosa color > nasal septum > sinuses
inspection inspection inspection palpation
symmetrical, smooth, tan pinkish oval and symmetrical nares not tender
Mouth and Throat
> lips
inspection
> sublingual area > tongue > teeth
inspection inspection inspection
slightly brown, symmetrical, dry, icteric (jaundice) pinkish, dry 19 teeth, with dental caries
> throat
inspection palpation
no swelling noted no pain when palpated
auscultation auscultation
100 bpm clear
inspection inspection inspection
symmetrical 32 bpm, tachypneic rapid and shallow
auscultation
vesicular
> contour > texture
inspection palpation
> frequency and character
auscultation
globular mild tenderness on right upper quadrant soft gurgling sound
Cardiovascular
> heart rate > heart sounds Thorax and Lungs
> symmetry > respiratory rate > breathing pattern > lung/breath sounds Abdomen
Upper Extremities
> skin color > size
inspection inspection
> symmetry
inspection
Lower Extremities
dark-skinned equal and appropriate for his body symmetrical
> skin color > size
inspection inspection
> symmetry
inspection
dark-skinned equal and appropriate for his body symmetrical
Neurologic
> level of consciousness
interview inspection,
> behavior and appearance
interview
> mood and affect
inspection, interview inspection, interview
>thought process
II. II.
responds quickly but he needs to ask again the question poor eye contact, does not pay attention to questions and tells his sister to answer quite irritable blunted affect there are questions that pertains to him that he cannot recall
PERS PERSON ONAL AL/ / SOCI SOCIAL AL HIST HISTOR ORY Y
The patient drinks 2 cups of coffee everyday. He could consume a pack of cigarette in one day. He started smoking when he was 25 years old. He can drink 1 bottle of Ginebra almost each day and he drinks more when he is with his co-workers and friends. He spends spends more time time travel travellin ling g becaus because e of the nature nature of his work. They They delive deliver r religious icons and images from Northern Luzon to Central Visayas region. His last travel was in Cagayan. There was limited time for him to socialize or to attend family gatherings.
He is the eldest child in their family. He was only a high school graduate but he decided to work immediately for his family.
III. ENVIRONME ENVIRONMENTAL NTAL HISTORY HISTORY (LIVING/N (LIVING/NEIGH EIGHBORHO BORHOOD/CI OD/CIRCUMS RCUMSTANCE TANCES) S)
The family is not well-off but they can manage to survive and meet their basic needs. He lives with his aunt’s family in a subdivision. The neighborhood is quiet and peaceful. The patient said there are no circumstances that could endanger their lives. There were no incidents of crime or illegal activities in the vicinity. There were no piggeries or poultry that could be a health hazard for them.
IV.
INTRODUCTION Ascending Cholangitis or acute cholangitis is an infection of the bile duct, usually caused by a bacteria ascending fr from om its junction with the duodenum duodenum (first part of the small intestine intestine. . It tends tends to occur if the bile ducts ducts are already already partially partially obstructed obstructed by gallstones.
In 1877, Charcot described cholangitis as a triad of findings of right upper quadrant (RUQ) pain, fever, and jaundice. The Reynolds pentad adds mental status changes and sepsis to the triad. triad. A spectrum spectrum of cholangiti cholangitis s exists, exists, ranging ranging from mild symptoms symptoms to fulminant fulminant overwhelming sepsis. With septic septic shock shock , the the diag diagno nosi sis s can can be missed missed in up to 25% of patients. Consider Consider cholangitis in any patient who appears septic, especially in patients who are elderly, elderly, jaundice jaundiced, d, or who have abdominal abdominal pain. pain. A history history of abdomina abdominal l pain or symptoms of gallbladder colic may be a clue to the diagnosis. Chol Cholan angi giti tis s can can be life life-t -thr hrea eate teni ning ng and and is rega regard rded ed as a medi medica cal l emer emerge genc ncy. y. Characteristic symptoms include include jaundice, fever, abdominal abdominal pain, and and in severe cases, low blood pressure and confusion. Initial treatment with intravenous fluids and antibiotics, but there is often an underlying problem (such as gallstones or narrowing in the bile duct) for
which further tests and treatments may be necessary, usually in the form of endoscopy to relieve obstruction obstruction of the bile duct. Bile duct obstruction, which is usually present in acute cholangitis is generally due to gallstones. gallstones. 10-30% of cases, cases, however, are due to other other caused caused as benign stricturing (narrowing of the bile duct without an underlying tumor), postoperative damage or an altered structure of the bile ducts such as narrowing at the site of an anastomosis (surgical connection) and various tumors ( cancer of the bile duct , gallbladder cancer, cancer , cancer of the ampulla of Vater , pancreatic cancer or cancer of the duodenum ). Cholangitis may also complicate medical procedures involving the bile duct, especially ERCP. To prevent this, it is recomm recommend ended ed that that those those underg undergoin oing g ERCP ERCP for any indica indicatio tion n receiv receive e prophy prophylac lactic tic (preventive) antibiotics.
VI. VI.
ANAT ANATOM OMY Y AND AND PHYS PHYSIO IOLO LOGY GY
Anatomy of the Biliary System:
The biliary system consists of the organs and ducts (bile ducts, gallbladder, and associated structures) that are involved in the production and transportation of bile. The transportation of bile follows this sequence: 1. When the liver cells secrete secrete bile, it is collected collected by a system of ducts that flow flow from the liver through the right and left hepatic ducts. 2. These ducts ultimately ultimately drain into the common common hepatic duct. duct.
3. The common hepatic duct duct then joins with the cystic cystic duct from the gallbladder gallbladder to form the common bile duct, which runs from the liver to the duodenum (the first section of the small intestine). 4. However, not all bile runs runs directly into the duodenum. duodenum. About 50 percent percent of the bile produced by the liver is first stored in the gallbladder, a pear-shaped organ located directly below the liver. 5. Then, when food is eaten, eaten, the gallbladder contracts contracts and releases stored stored bile into the duodenum to help break down the fats. Functions of the Biliary System:
The biliary system's main function includes the following: •
to drain waste products from the liver into the duodenum
•
to help in digestion with the controlled release of bile
Bile is the greenish-yellow greenish-yellow fluid (consisting of waste products, cholesterol, and bile salts) that is secreted by the liver cells to perform two primary functions, including the following: •
to carry away waste
•
to break down fats during digestion
VIII. LABORATORY AND DIAGNOSTIC EXAMINATIONS EXAMINATIONS Date: October 3, 2009 Prothrombin Time (PT)
Patient’s Time 17.1 seconds (done twice)
Normal Values 10-14 seconds
Significance prolonged PT my suggest hepatic disease, deficiencies in fibrinogen, prothrombin, Vit K or
factors V, VII, or X Activated Partial Thromboplastin Time (APTT)
Patient’s Time 52.1 seconds (done twice)
Normal Values 26 - 36 seconds
Significance prolonged APPT my suggest deficiencies in coagulation factors (Vit. K)
Date: October 5, 2009 Blood Chemistry
Results
Normal Values
Significance
BUN
6.89 mmol/L
2.9 – 8.2 mmol/L
within normal range
Creatinine
176.8 µmol/L
53 -106 µmol/L
an increase may suggest renal disease
Hepatic Enzymes
SGOT/AST
Results 7.1 U/L
Date: October 6, 2009
Normal Values 8 – 33 U/L
Significance low levels suggests lack of Vitamin B 6
Whole Abdominal Ultrasound
R MidMid-he hepa pati tic c Leng Length th L MidMid-he hepa pati tic c Leng Length th Common Bile Duct Main Portal Vein Spleen R Kidney L Kidney Prostate Gland •
• • • • •
• •
= = = = = = = =
17.9 17.9 cm cm 12.4 12.4 cm cm 1.5 cm 1.3 cm 8.7 x 3.8 cm 10.2 x 4.9 x 4.7 cm 10.6 x 5.1 x 5.3 cm 2.5 x 2.9 x 3.1 cm (11.6 gms)
The liver is enlarged without focal lesion. Common bile duct and intrahepatic ducts are dilated. Extrahepatic portions portions of the common bile duct are obscured by bowel gas. Markedly distended gallbladder is noted Gallbladder is adequately distended without intraluminal echoes or wall thickening Pancreas cannot be properly evaluated due to presence of bowel gas Spleen is unremarkable Both Both kidney kidneys s are within within normal normal size size config configura uratio tion, n, parenc parenchym hymal al echopa echopatte ttern, rn, and cortical thickness. No focal lesion, ectasis, or lithiasis noted Prostate gland is normal in size without calcifications Urinary bladder is underfilled with note of foley catheter
Impression: Hepatomegaly with biliary obstruction Markedly distended gallbladder vs. bowel loop Underfilled urinary bladder
Date: October 7, 2009
Results
Blood Chemistry
Total Bilirubin
47.5
Direct Bilirubin
17
Normal Values 2 - 21 mmol/L
<5 µmol/L
Significance increased values may suggest hepatitis, biliary stricture
increased values may suggest biliary obstruction
(B1) increased values may suggest hepatic damage Indirect Bilirubin
Electrolytes
Sodium
Potassium
30.5
Results 152.4 mmol/L
2.90 mmol/L
2 – 17 µmol/L
Normal Values 136 - 142 mmol/L
3.8 – 5.0 mmol/L
Significance increased values may suggest impaired renal function
decreased values may suggest gastrointestinal gastrointestinal and renal disorders
Chloride
Hematology
121.7 mg/L
Results
95 – 103 mg/L
Normal Values
Blood Type
Type O+
WBC
17.6 G/L
4.1 – 10.9 G/L
RBC
3.68 T/L
4.2 – 6.30 T/L
increased values may suggest severe dehydration or complete renal shutdown
Significance
-increased values may suggest infection -decreased values may suggest anemia -decreased values may suggest
HGB
112 g/L
120 – 180 g/L
anemia, recent hemorrhage or fluid retention -decreased values may suggest anemia, hemodilution
HCT
360 L/L
370 – 510 L/L -decreased values may suggest
Platelet
66 g/L
140 – 440 G/L
immune disorders, Vit B 12 deficiencies
XI.
DRUG STUDY Generic Name: Cefuroxime Dosage: 750 mg IVP q 8° Indication: it is used as an anti-infective agent for urinary tract infections and severe
infections
Mechanism of Action
Inhibits bacterial cell wall synthesis, rendering cell wall osmotically unstable, leading to cell death
Side Effects
diarrhea, nausea and vomiting, gas or heartburn
Contraindications
Hypersensitivity to cephalosporins and related antibiotics; pregnancy (category B), lactation
Adverse Reactions
Allergic reactions like skin rash, itching or hives, swelling of the face, lips or tongue, dark urine, difficulty of breathing, irregular heartbeat or chest pain, seizures, unusual bleeding or bruising, white patches or sores inside the mouth
Nursing Considerations •
•
•
•
Generic Name: Metronidazole Dosage: 500 mg IV infusion q 8°
Determine history of hypersensitivi ty reactions to cephalosporins , penicillins, and history of allergies, particularly to drugs, Inspect IM and IV injection sites frequently for signs of phlebitis. Monitor I&O rates and pattern: Monitor for bleeding
Indications: It is used for the treatment of serious infection caused by susceptible
postoperative
anaerobic bacteria in intra-abdominal intra-abdominal infections, skin infections, gyne gyneco colo logi gic c infe infect ctio ions ns, , sept septic icem emia ia, , and and for for preo preope pera rati tive ve prophylaxis
Mechanism of Action
Side Ef E ffects
Contraindications
It binds to bacterial and protozoal DNA to cause loss of helical structure, strand breakage, inhibition of nucleic acid synthesis and cell death.
GI discomfort, anorexia, nausea, furred tongue, dry mouth and unpleasant metallic taste, headache, less frequently vomiting, diarrhea, weakness, dizziness and darkening of the urine. Watery (tearing) eyes if applied near to eye area, transient redness and mild dryness.
Blood dyscrasias. Active CNS diseases. Hypersensitivity to imidazole. Tuberculosis to mucous membranes and certain viral conditions. 1 st trimester of pregnancy. Lactation. Children. Leukopenia. Peripheral neuropathy (long term therapy). Psychiatric disorders.
Adverse Reactions
Convulsive seizures; peripheral neuropathy; rash, pruritus. Burning and skin irritation
Nursing Considerations •
•
•
Obtain baseline information on patient’s infection: fever, wound characteristics, WBC count (>100,000mm3) and regularly assess during treatment. Assess for allergic reactions: rash , urticaria, pruritus. Monitor renal function: urine output, inputoutput ration, polyuria,dysuria , pyuria, BUN and creatinine. Decreasing
and and
•
•
output and increasing BUN, creatinine may indicate nephrotoxicity. Monitor bowel pattern, discontinue drug if severe diarrhea occurs. Assess for over growth of infection: peripheral itching, fever malaise, redness, swelling, drainage, rash and change in cough/sputum.
Generic Name: Paracetamol Dosage: 300mg IVP q 4° for temp ≥ 38.5 °C Indication: To relieve mild to moderate pain due to things such as headache, muscle and
joint pain, backache and period pains. It is also used to bring down a high temperature .
Mechanism of Action
Side Effects
Contraindications
Adverse Reactions
Decrease fever by inhibiting the effect of pyrogens of the hypothalamic heat regulating centers by a hypothalaminc action leading to sweating nd vasodilation relieves pain by inhibiting prostagalandin synthesis in CNS does not have inflammatory action because of its minimal effect
Side effects are rare with paracetamol when it is taken at the recommended doses.
Hypersensitivity to acetaminophen or phenacetin; use with alcohol.
Skin rashes, blood disorders and acute inflammation of the pancreas have occasionally occurred in people taking the drug on a regular basis for a long time. One advantage of paracetamol over aspirin and NSAIDs is that it doesn't irritate the stomach or causing it to bleed, potential Side effects of aspirin and NSAIDs.
Nursing Considerations •
•
•
Assess patients fever or pain: type of pain, location, intensity, duration, temperature, diaphoresis Assess allergic reactions: rash, urticaria; if this occur, drug may have to discontinued Assess hepatotoxicity; dark urine, claycolored stools, yellowing of skin and sclera; itching, abdominal pain, fever, diarrhea if patient is on
long term therapy. •
•
•
Monitor liver and renal function. AST, ALT bilirubin, protime, BUN, CREA Check input and output ratio; decreasing output may indicate renal failures (long-term therapy) Assess for chronic poisoning: rapid, weak pulse; dyspnea: cold, clammy extremities; report immediately to prescriber
Generic Name: Pantoprazole Dosage: 80 mg IV infusion Indications: Gastric acid pump inhibitor Mechanism of Action
Inhibits both basal and stimulated gastric secretions by suppressing the final step in acids production, through the inhibition of the proton pump by binding to and inhibiting hydrogenpotassium adenosine triphosphatase, the enzyme system located at the secretory surface of the gastric
Side Effects
Contraindications
Adverse Reactions
Headache, diarrhea, abdominal pain, rash
Hypersensitivity. Moderate to severe hepatic or renal dysfunction.
Insomnia, flatulence, hyperglycemia
Nursing Considerations
•
•
•
•
•
Assess for underlying condition before therapy and regularly thereafter to monitor drug effectiveness. Assess GI symptoms: epigastric/abdomina l pain, bleeding and anorexia. Monitor for possible druginduced adverse reactions Monitor hepatic enzymes: AST, ALT, alkaline phosphatase during treatment Assess patient and family’s knowledge
parietal cell.
on drug therapy.
Generic: Vitamin K/ Phytomenadione Phytomenadione Dosage: 1 amp IVP q 8° Indication: Used in the treatment and prevention of hemorrhage associated with Vitamin K deficiency Mechanism of Action
Side E ff ffects
Synthetic analog of Vit. K w/c is essential to hepatic synthesis of blood clotting factors II, VII, IX, X.
Hypotension, cyanosis, headache, dizziness, rash. Anaphylactoid reactions; pain, swelling
Contraindications
Pronounced allergic diathesis. Infants<1 yr.
Adverse R ea eactions
Urticaria. Hyperbilirubinemia including kernicterus. In newborns. death after IV injection. Pruritic erythematous plaques at IM injection site.
Nursing C on onsiderations
•
•
•
•
Assess for patients condition before therapy and regularly thereafter to monitor drug effectiveness. Assess for bleeding: bruising, hematouria, black- tarry stools and hematemesis. Monitor for possible drug- induced adverse reactions Assess patient and family’s knowledge on
drug therapy
X.
Iden Identi tifi fied ed Prob Proble lems ms Acco Accord rdin ing g to to Pri Prior orit ity y
1. Ineffective breathing breathing pattern related related to decreased lung expansion expansion secondary to liver liver enlargement
2. Acute pain related to ductal ductal spasm secondary secondary to biliary duct obstruction obstruction 3. Hyperthermia related related to presence presence of disease process
XI. NURSING CARE PLAN Assessment
Nursing Diagnosis
S> “hinahabol ko ang aking hininga” as verbalized by the client O> - rapid and shallow breathing -nasal flaring noted -use of accessory muscles
Vital Signs:
Ineffective breathing pattern related to decreased lung expansion secondary to liver enlargement
Scientific Background The liver is located immediately below the diaphragm which is the major muscle of respiration. Upon enlargement of the liver, it compresses the diaphragm upward thus decreasing lung expansion during inspiration resulting to rapid and
Goals
After 2-3 hours of rendering proper nursing intervention , the client will demonstrate easier respiration and respiratory rate will decrease from 32 bpm to 22 bpm
Interventions
> assess and monitor vital signs
> monitor respiratory status
> place client in sitting/high fowler’s position
> provide adequate ventilation
Rationale
> serve as baseline data
> to note for worsening of tachypnea
> it allows good lung excursion and chest expansion
> to facilitate effective breathing
Evaluation
Goal partially met. After 3 hours of rendering proper nursing intervention, the client demonstrated easier respiration and respiratory rate decreased from 32 bpm to 25 bpm
RR: 32 bpm BP: 110/80 mm Hg
shallow breathing pattern
> ensure O 2 delivery system is applied to the patient
CR: 100 bpm T: 39.6°C
> refer to physician accordingly during tachyneic episodes
> so that appropriate amount of oxygen is continuously delivered
> to assess respiratory status
> explain effects of wearing restrictive clothing
> teach patient appropriate breathing techniques by demonstration emphasizing slow inhalation,
> use of tight or restrictive clothing compromises respiratory excursion
> appropriate breathing techniques are important in maintaining
holding end inspiration for a few seconds and passive inhalation
adequate gas exchange
Assessment
Nursing Diagnosis
S> “masakit ang tiyan ko” as verbalized by the client
O> - facial grimace - with guarding behavior noted - restlessness - pale and weak in appearance - rated pain
as 6/10 in a pain scale of 1-10; 1 as the
Acute pain related to ductal spasm secondary to biliary duct obstruction
Scientific Background As the biliary duct becomes obstructed, the pressure within the bile duct increases thus producing involuntary contraction usually accompanied by pain that may last from seconds to minutes
Goals
After 4 hours of rendering proper
Interventions
> monitor vital signs
nursing intervention , the patient’s level of pain of 7/10 will subside to 3/10
> perform a comprehensive assessment of pain to include location, onset/ duration, quality, severity and precipitating factors
Rationale
> to monitor any changes from the previous to present data. Serve as baseline data
> to assess etiology/ contributing factors
Evaluation
Goal partially met. After 4 hours of rendering proper nursing intervention, the patient’s level of pain subsided from 7/10 to 4/10
lowest and 10 as the highest
> determine possible pathophysiolog ical causes of pain
Vital Signs:
BP: 110/80 mm Hg
> to assess precipitating factors
> perform pain assessment each time pain occurs
RR: 32 bpm CR: 100 bpm T: 39.6°C
> provide comfort measures
> provide calm and quiet environment
> administer analgesics as indicated
> instruct the patient to report pain
> to rule out worsening of underlying condition
> to provide nonpharmacological pain management
> to prevent anxiety
> to maintain acceptable level of pain
> explain cause of pain, if known
> instruct the patient to evaluate and report effectiveness of measures used
> so that immediate relief measures may be instituted
> this will contribute to patient’s understanding to his condition
> it will determine if measures used were not effective to facilitate better interventions
Assessment
Nursing Diagnosis
S> “sobrang init ko” as verbalized by the patient
O> - febrile (39.6 °C) - flushed skin - warm to touch -diaphoretic > pale and weak in appearance
Hyperthermia related to disease process
Scientific Background During inflammation or infection, the area of infection or infection phagocyte releases endogenous pyrogens (fevercausing substance). These will act as receptors in the hypothalamus to cause upward alteration of its temperature set point
Goals
After 1-2 hours of rendering proper
Interventions
> monitor vital signs
nursing intervention , the patient’s temperature will subside from 39.6°C to 37°C or maintain body temperature within normal range (36.5°C – 37.5°C)
> remove excess clothes or blanket
> perform TSB
Rationale
> to monitor any changes from the previous to present data. Serve as baseline data
> to promote heat loss through evaporation
> TSB opens the skin pores therefore facilitating conduction and evaporation of heat from a warm surface to a cool surface
Vital Signs:
> to reduce metabolic
Evaluation
Goal met. After 1-2 hours of rendering proper nursing intervention, the patient’s temperature subsided from 39.6°C to 37.5°C.
BP:
demands
110/80 mm Hg RR: 32 bpm
> to support circulating volume and tissue
CR: 100 bpm T: 39.6°C > provide adequate rest
> administer fluid an electrolyte replacement
> administer medications as indicated
> explain temperature measurements
perfusion
> to treat underlying cause
> this will provide patients knowledge how to assess their temperature; this will provide information on how to prevent or control temperatures especially when they were already
and all treatments
discharged
> provide information regarding normal temperature and control > discuss precipitating factors and preventive measures
XII. ONGOING APPRAISAL October 8, 2009
Patient XYZ’s condition has improved. He is not experiencing abdominal pain. His NGT and IFC were removed. He is already allowed to have general liquids on his diet. Patient Patient is with ongoing Pantoprazole drip. October 9, 2009
The patien patient t is allowe allowed d to Medications are still continued.
have have
soft soft
diet. diet.
Pantop Pantopraz razole ole drip drip
was discon discontin tinued ued. .
October 10, 2009
Patien Patient t is reques requested ted to have have anothe another r abdomi abdominal nal ultras ultrasoun ound d to confir confirm m bile bile duct duct obstruction. If confirmed, the patient may be transferred to surgery ward. October 11, 2009
The patient is not experiencing abdominal pain, fever and shortness of breath. The patient is still for abdominal ultrasound. October 12, 2009
The patient may be transferred to regular ward. The patient is still for abdominal ultrasound for confirmation of common bile duct obstruction. XIII. DISCHARGE PLAN M – Medicine
- advise patient to continue his prescribed medicines E – Environment and Exercise
- maintain a quiet environment to promote relaxation - provide clean and comfortable environment - encourage walking everyday T – Treatment
- continue home medications - advise patient to take multivitamins for increased immunity - teach patient about wound care H – Health Teachings
- provide oral and written instructions about wound care, activity, diet recommendations, recommendations, medications, and follow-ups O – Out-Patient Follow-Up
- patient will be advised to go back to the hospital in a specific date to have a follow-up check-up after discharge D – Diet and Danger Signs
- encourage patient to increase protein intake for tissue repair
at
- advise patient and family members to immediately consult if the patient is experiencing any likely symptoms, or changes that may occur when the patient is home.
VII. PATHOPHYSIOLOGY PATHOPHYSIOLOGY (Ascending Cholangitis)
Biliary tract obstruction (gall stone, neoplasm, or stricture) (Main Factor of Pathogenesis) Elevated Intraluminal Pressure
Walls of biliary tract become distended Occlusion of lymphatic channels then the venous return and arterial supply to the biliary tract becomes undermined Reduced blood supply to the biliary tract
Diminished host antibacterial defenses
Immune System Dysfunction
Decreased oxygenation
Walls of biliary tract starts to break Bacteria gain access to the biliary tree
Bacteria start to multiply
Bacteremia
Invasion of bacteria (E.coli 27%, Klebsiella species 16%, Enterococcus species 15%,Sreptococcus 15%,Sreptococcus species 8%, Enterobacter species 7%, Pseudomonas aeruginosa 7% Retrograde ascend from duodenum or from portal venous blood to the hepatic ducts, biliary canaliculi, hepatic veins and perihepatic lymphatics Charcot’s triad:fever, RUQ
pain,jaundice Reynold’s pentad:altered mental
status, hypotension,RUQ pain, fever and jaundice Unclassical signs:pruritus,
malaise and tacycardia