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Pathophysiology of Appendicitis (Ruptured\) Modifiable Diet: eople !hose !ho se diet is lo! in fi"er and ri#h in refined #ar"ohydrates $nfe#tio ns: Gastrointestinal Gastroint estinal $nfe#tions: infe#tions su#h as Ame"iasis% &a#terial Gastroenteritis% 'umps
Non-modifiable Age: 11-20 yrs old Gender: male (male- female =2:1) Hereditary: tumor formation in the opening of the appendix
Obstruction of the appendix by (fecalith (hardened stool) lymph node tumor foreign ob!ects)
"ncrease in pressure inside the appendix lumen that result to distention of appendix
"mpaired #enous return causing hyperemia (improper O$ and nutrient supply) Normal bacteria found in appendix begin to in#ade (infect) the lining of the %all
"nflammatory Response & body response to the bacterial in#asion in the %all of appendix' "ncreased "mmune complex (disease plus antibody) causes s%elling of tissue resulting to inflammation of appendix * abdominal pain, fever, and increase swelling of appendix . Vomiting and loss of appetite
Pain- located @ RLQ, causing Guarding, Vomiting & loss of appetite
Appende#tomy !ith explore laparotomy
inflammation and infection spread infection spread through the %all of the appendix causing death of tissue' +he appendix ruptures due to increase pressure (Perforation)
Appendectomy pain medications
erforation (formation of a hole in an organ)% fe#al materials exits to peritoneal #aity #ausing formation of a"s#esses (periappendi#eal a"s#ess) $nfe#tion #an spread throughout the a"domen (peritoneal #aity)
&a#terial inasion of eritoneal *aity #ausing inflammation of the mem"rane that lines the a"domen peritoneum (eritonitis) S/S: swelling of the abdomen, severe pain, and weight loss
+epsis (the #ondition or syndrome #aused "y the presen#e of mi#roorganisms or their toxins in the tissue or the "loodstream ) +epte#emia
