Pathology Cell Injury

Pathology – cell injury and adaptation MCQ 1

Irr Irreversib sible ce cell in injury jury is asso assocciate ated with a) Clum Clumpi ping ng of chro chroma mati tin n  b) ndoplasmic swelling c) !educe !educed d o"idat o"idative ive phosp phosphor horyl ylatio ation n d) Profou Profound nd memb membrane rane distur disturban bance ce e) #atty atty chan chang ge

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%ystrophic ca c alcification a) &ccu &ccurs rs in in nor norma mall tissu tissues es  b) Is associated with hypercalcaemia c) Is seen seen in vitamin vitamin % relate related d disea disease se d) &ccurs &ccurs in atherom atheromatou atouss diseas diseasee e) May be a part part of of the mil' mil' al'ali al'ali syn syndro drome me

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!ega !egard rdin ing g meta metast stat atic ic calc calcif ific icat atio ion n whic which h stat statem emen entt is inco incorr rrec ectt a) ffects ffects 'idn 'idneys eys and and lungs lungs more more than than the liver  liver   b) Is seen in organs that have a relatively al'aline compartment c) Is init initiate iated d in the mitoch mitochond ondria ria d) &ccu &ccurs rs in in norm normal al tis tissu sues es e) Is ofte often n seen seen in in the the pulm pulmona onary ry veins veins

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!ega !egard rdin ing g hype hyperp rpla lasi siaa whic which h stat statem emen entt is corr correc ectt a) It is neve neverr seen in the the same same tissue tissue as hypert hypertrop rophy hy  b) it is seen in cardiac muscle in hypo"ic patients c) it is limite limited d to cells cells capable capable of of mitotic mitotic divis division ion d) it is is rarely rarely phys physio iolo logi gicc e) complete complete removal removal of e"cess hormo hormone ne triggers triggers will slow progres progression sion but but not reverse hyperplastic changes

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ischaemic injury a) May be be caused caused by any state state of reduced reduced o"ygen o"ygen delivery delivery  b) Is associated with an efflu" of calcium and sodium c) ,eads ,eads to redued redued gly glycoly colycis cis in the cell cell d) ,eads to cessation cessation of cardiac cardiac muscle muscle contraction contraction in appro" appro" 1+ 1+ minutes minutes of coronary occlusion e) -sually -sually resu results lts in a necro necrotic tic patter pattern n of injury injury

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