Far Eastern University Institute of Nursing BATCH 2012
Navor, Pros Mervin BSN 223
DRUG STUDY
Name
Diazepam Antenex‡, ApoDiazepam†, Diastat, Diazemuls‡, Diazepam Intensol, Ducene‡, NovoDipam†, PMSDiazepam†, Valium, Vivol†
Dosage
Injection: 5 mg/ml Oral solution: 5 mg/5 ml, 5 mg/ml Rectal gel twin packs: 2.5 mg (pediatric), 5 mg (pediatric), 10 mg, 15 mg (adult), 20 mg (adult) Tablets: 2 mg, 5 mg, 10 mg
Classification
anxiolytic, skeletal muscle relaxant, amnesic, anticonvulsant, sedativehypnotic Therapeutic Action: A benzodiazepine that probably potentiates the effects of GABA, depresses the CNS, and suppresses the spread of seizure activity.
Indication
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Anxiety Acute alcohol withdrawal Before endoscopic procedures Muscle spasm Preoperative sedation Cardioversion Adjunct treatment for seizure disorders Status epilepticus, severe recurrent seizures Patients on stable regimens of antiepileptic drugs who need diazepam intermittently to control bouts of increased seizure activity
Contraindication
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Contraindicated in patients hypersensitive to drug or soy protein; in patients experiencing shock, coma, or acute alcohol intoxication (parenteral form); in pregnant women, especially in first trimester; and in children younger than age 6 months (oral form). Diastat rectal gel is contraindicated in patients with acute angle-closure glaucoma. Use cautiously in patients with liver or renal impairment, depression, or chronic open-angle glaucoma. Use cautiously in elderly and debilitated patients.
Side Effects
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CNS: drowsiness, dysarthria, slurred CV: hypotension, CV collapse, bradycardia. EENT: diplopia, blurred vision, nystagmus. GI: nausea, constipation, diarrhea with rectal form. Hematologic: neutropenia. Hepatic: jaundice. Respiratory: respiratory depression, apnea. Skin: rash. Other: altered libido, physical or psychological dependence, pain, phlebitis at injection site.
Nursing Responsibility •
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Use of this drug may lead to abuse and addiction. Don't withdraw drug abruptly after longterm use; withdrawal symptoms may occur. Alert: Only caregivers who can distinguish the distinct cluster of seizures or events from the patient's ordinary seizure activity, who have been instructed and can give the treatment competently, who understand which seizures may or may not be treated with Monitor periodic hepatic, renal, and hematopoietic function studies in patients receiving repeated or prolonged therapy. Monitor elderly patients for dizziness, ataxia, mental status changes. Patients are at an increased risk for falls.
