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drugs study
Full description
Drug Study: Ambroxol Dosage and Administration Mucolytic; Adults : 1 Secretolytic prolonged action Ambroxol is used for therapy in capsule once infections of the acute and daily, either in the upper respiratory tract. tract . It chronic morning or clears airways and eases bronchopulmo evening after a Generic cough. nary diseases meal Name: Properties: associated The capsules Ambroxol Ambroxol is used for with abnormal should not be Hydrochlori infections of the upper mucus opened or de respiratory tract. It clears secretion and chewed, but airways and eases cough. impaired swallowed whole Manufactur Preclinically, Preclinically, ambroxol, the mucus with ample liquid. liquid. er: active ingredient of transport. The "carrier Boehringer MUCOSOLVAN, has been tablets" which are -Ingelheim shown to increase occasionally respiratory tract secretion. present in the It enhances pulmonary stools have surfactant production and released the active stimulates ciliary activity. substance during These actions result in their passage improved mucus flow and through the transport (mucociliary (mucociliary digestive system clearance). clearance ). Improvement and are therefore of mucociliary clearance without has been shown in significance. clinical pharmacologic stud MUCOSOLVAN ies. Enhancement of fluid prolonged action secretion and mucociliary capsules are not clearance facilitates suitable for expectoration and eases children under 12 cough. years. Name of Drug Brand Names: Mucosolva n and Mucoangin
Action and Properties
Indications
Contra indications MUCOSOLVA N should not be used in patients known to be hypersensitiv e to ambroxol or other components of the formulation.
Side Effects MUCOSOLVAN is generally well tolerated. Mild upper gastrointestinal side effects (primarily pyrosis, dyspepsia, and occasionally nausea, vomiting) have been reported, principally following parenteral administration. Allergic reactions have occurred rarely, primarily skin rashes. There have been extremely rare case reports of severe acute anaphylactic-type reactions but their relationship to ambroxol is uncertain. Some of these patients have also shown allergic reactions to other substances.
Nursing Consideration Assessment & Drug Effects •Monitor for S&S of aspiration of excesssecretions, excesssecretions, and forbronchospasm(unp redictable);withhold drug and notify physician immediately if eitheroccur. •Lab tests: Monitor ABGs, pulmonary functions and pulse oximetry as indicated. •Have suction apparatus immediately available. Increased volume of respiratory tract fluid may be liberated; suction orendotracheal aspiration may be necessary to establisha nd maintain an open airway. Patient & Family Education •Report difficulty with clearing the airway or any other respiratory distress
