DRUG’S NAME
MECHANISM OF ACTION
ADMINISTRATION
INDICATION
CONTRAINDICATION CONTRAINDICATION
ADVERSE EFFECT
NURSING RESPONSIBILITIES
GENERIC NAME: Ranitidine hydrochloride
Competitively inhibits the action of histamine at the H2 receptors of the parietal cells of the stomach, inhibiting basal gastric acid secretion and gastric acid that is stimulated by food, insulin, histamine, cholinergic agonist, gastrin, and pentagastrin.
DOSAGE: 150 mg
*Short term treatment of active duodenal ulcer
*contraindicated with allergy to ranitidine, lactation.
CNS: Headache, malaise, dizziness, somnolence, insomnia, vertigo
HISTORY: Allergy to ranitidine, impaired renal or hepatic function, lactation, pregnancy
BRAND NAME: Gen- Ranitidine (CAN)
ROUTE: Po FREQUENCY: Bid
*maintenance therapy for duodenal ulcer at reduced dosage. *short term therapy treatment and maintenance therapy of active, benign gastric ulcer ulcer *short term treatment for GERD *phatologic hypersecretor y conditions *treatment of
*use cautiously with impaired renal or hepatic function, pregnancy.
CV: Tachycardia, bradycardia DERMATOLOGIC: Rash, alopecia GU: Gynecomadtia, impotence, decrese libido GI: Constipation, diarrhea, nausea, vomiting, abdominal pain, hepatitis. HEMATOLOGIC: Leukopenia, thrombocytopenia , pancytopenia.
PHYSICAL: Skin lesions, baseline ECG, liver evaluation, abdominal examination. INTERVENTION: -administer drug with meal and at bed time. -provide concurrent antacid therapy to relieve pain. TEACHING POINTS: -Take drug with meal and at bed time. May continue 3-4 weeks or longer. -report sore throat, unusual bruising or bleeding, tarry stools, severe headache, muscle or joint pain.
erosive esophagitis *treatment of heartburn, acid indigestion, sour stomach
