Recap IMMUNOLOGY AND SEROLOGY, Intensive Recap ISBB, Medtech review blood bank, Intro to medtech (BB) Study online at quizlet.com/comb quizlet.com/combine/108592495 ine/108592495,110693773,1 ,110693773,144790205,144 44790205,144842779 842779 1.
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Not more than twice a week
2.
<1 kda
Non immunogenic
3.
<6 kda
Weakly immunogenic
4.
1/2 inch
Secure the needle by threading it up the vein by how many inch?
5.
1.06
6.
31. 24
hrs
Gy (2500 rads)
Minimum dose for irradiation of RBC at the center of blood bag
33.
37 'C +
IgG
Conversion factor of grams to mL
34.
45 days
Longets duration of blood
1-10•c
Transport temperature for RBC components
35.
Angle of the needle to the skin for bleeding
7.
1 month
Deferral for Accutane
45• reduce to about 10-20• once in skin
8.
1 month (other name of accutane)
Isotretinoin
36.
48 hours
Interval between plateletpheresis
37.
48 hours
Apheresis
1 week
Double- or triple-platelet product
38.
50-100
Pulse rate for donation
Shelf life of heparin as anticoagulant
39.
56 degree celcius for 30 minutes
Complement inactivation, 4 hours valid if not used heat again for 10 minutes
9.
10. 2 11.
days
2 months
32. 25
RBC shelf life after hermetic seal is broken (16•c)
Deferral for recent blood donation
12. 2
weeks
Measles
40.
PPF and NSA are pasteurized:
13. 2
weeks
Deferral for mumps, rubeola, yellow fever, polio, typhoid live attenuated vaccine
60•c for 10 minutes
41.
-65 •c
Storage of FFP (7 years)
42.
72 hours
Aspirin
43.
72 hours
Tooth extraction
44.
80 IU of factor VIII 150 mg/dL of Fibrinogen
Cryoprecipitate must contain
45.
130 pounds 5'1"
Double RBC pheresis: Height and Weight requirement for male
46.
150 pounds 5'5"
Height and Weight requirement for female
47.
170-260 microns
1st generation filter
48.
AABB: 1 year NVBSP: 6 months
Travel to malarial endemic country
49.
AABB: 3 years Resident in a malarial endemic country (>3 NVBSP: 1 year years)
50.
ACD
Most common anticoagulant for apheresis
14.
3.0 x10^10 platelets
SDP
15.
3-4 days
Transfused platelets have a life span of
16.
4 hours
Unit should be transfused
17.
4 weeks
German measles
18.
4 weeks
Chicken pox
19.
5,00010,000/uL
RDP will raise patient's platelet count up to
20.
5.5 x10^10 platelets
RDP
21.
6-8 units of pooled platelets
1 SDP is equivalent to
10.5 mL/kg
Maximum amount of blood that could be collected in a donor (including the sample for testing)
22.
23.
10 years
Previous ABO and Rh of patient must be retained for
24.
12 months
Dental surgery
51.
Acquired A
Tn activated erythrocytes c
25.
12 months/ 1 year
Previous ABO and Rh of patient must be available immediately for
52.
Activated B cell
26.
12 months/ 6 months
Rabies vaccine
Added marker CD25 (antigens,super antigens,mitogens: monoclonal,oligoclonal,polyclonal respectively),LPS ACTIVATED
15 minutes
Blood must be collected within
53.
27.
Activated T cell
CD 25 positive(Pag nagka experience kana)
28.
16-24 donors According to FDA and AABB, it is acceptable to screen donors for infectious diseases in pools of how many donors?
54.
Active
Antigen exposure
29.
-18 •c
30. 24
hours
Storage of Cryoprecipitate and FFP (1 year) Granulocyte concentrate
55.
Adaptive: cellular components
T( thymus dependent and majority of lymphocytes 60-80%)and B cells
56.
Adaptive: humoral compnents
Cytokines and antibodies
57.
Adaptve immunity
Specific and memory( mahilig magtanim ng galit )
58.
Adjuvants
Enhances immune response to an antigen ( alum precipitate,squaline,MF-59, Freud's complete adjuvants
59.
Adsol
AS-1
60.
Affinity
Association constant between Ab and a univalent Ag
61.
Agglutination 2
Antigen is soluble
62.
Albumin
Negative acute phase reactant
63.
Aldomet (alpha methyldopa) Chlorpropamide
Drugs that may produce autoantibody to Kidd
64.
Alloanti-Jk3
Looks like inseparable anti-JkaJkb
65.
Alpha interferon
Interferes viral replication,aka LEUKOCYTE INTERFERON, activated by NULL cells
Alternative pathways
LPS(gram neg bacteria)
67.
Antibodies
Tag antigens for destruction and removal
68.
Antibody
Are made up of PROTEINS
69.
Anticoagulant for DAT(in vivo)
EDTA
70.
Anti-M
Enhanced at an acidic environment
71.
Anti toxin
Antibodies against toxins
72.
Anti-U
Rare; formed in S-s- individuals; enhanced by enzyme
66.
73.
74.
APC(endocytose) Presents antigens to T CELLS, DENDRITIC CELLS,MACROPHAGES,Bcells ( connection from adaptive to innate immunity) Apheresis
whole blood is withdrawn, a desired component is separated and retained and the remainder of the blood is returned to the donor
75.
Apheresis or hemapheresis
To separate or remove/ to take away
76.
APRs with 2 or 4 times increase
Alpha 1 anti trypsin,fibrinogen,haptoglobulin
77.
APRs with 50% increase
Alpha 2 macroglobulin,C3, ceruloplasmin
78.
Artificial active
Antigen was injected (vaccination,toxoids)
79.
Artificial passive
Antibodies was injected ( anti toxin injection,HBIg,Rhogam)
80.
AS-3
Additive without mannitol
81.
Autoantibodies and autoimmune diseases SLE
RA
*Anti dsDNA abs Anti sm( smith) abs *Rheumatoid factor that targets Fc portion of another antibody( IgM against the Fc portion of IgG) *Antibodies against insulin or beta cell( produces insulin) *anti parietal cell antibodies
DM 1
Pernicious Anemia
Cells of the stomach that produces HCL and Intrinsic factor for the absorption of vitamin b12 *warm(Bind RBC at warm temp) and cold(bind RBC at rt or refrigerated temp) autoantibodies
Autoimmune Hemolytic Anemia
*anti microsomal abs(anti thyroid peroxidase antibody); anti thyroglobulin abs *anti TSH receptor abs or anti TSIg
Hashimotos Thyroiditis
Graves disease
*anti glomerular basement membrane abs
*anti neutrophilic abs Goodpasteure Syndrome
*anti centromere abs * abs to adrenal gland
CREST *anti myelin sheath abs Addisons diseas *anti acetylcholine receptor abs MS Myasthenia gravis *antibodies to platelets Primary biliary cirrhosis Chronic active hepatitis ITP
82.
Autoantibodies and autoimmune diseases SLE
RA
DM 1
" '
85.
Avidity
Measure overall binding between Ag binding sites and multivalent antigen
86.
B cells
Cortex,20-30%,capable of producing antibodies,humoral immune response,can be transferred to a normal serum with a serum from a hypersensitive individual
87.
Beta interferon
Aka Epithelial,fibroblast or fibroepithelial interferon; antiviral,produced by FIBROBLASTS
88.
Beta Lysin
Effective against gram postive EXCEPT strep,released by platelets
89.
Blood banking
the procedures involved in collecting, storing and processing blood and the distribution of RBCs & blood components
*warm(Bind RBC at warm temp) and cold(bind RBC at rt or refrigerated temp) autoantibodies
90.
Blood Collection
450mL w/ CPDA-1(citratephosphate-dexteose-adenine) coagulant; allows storage for up to 35 days.
*anti microsomal abs(anti thyroid peroxidase antibody); anti thyroglobulin abs
91.
Blood group systems
a group of antigens produced at a single gene locus or closely linked loci
92.
Blood transfusion
goal: 75% of the RBCs transfused from one person to another should remain viable for 24 hrs.
93.
Bombay (Oh)
No agglutination with anti-H
*anti glomerular basement membrane abs
94.
Bombay phenotype
Agglutination in O cells
95.
Bone marrow and thymus
Primary lymphoid tissue
*anti neutrophilic abs
96.
Bood type O
Greates amounts of H antigens
97.
BP
180/100 max
98.
C1 inh
Dissociates c1 complex, deficiency leads to HANE
99.
C1q
Bnds to Fc portion of IgG and IgM
100.
C1r
Activates C1s
101.
C1s
Cleaves C4 and C2
102.
C2
Binds to C4b to form C3 convertase
103.
C2 and C4 def
SLE LIKE SYNDROME
104.
C2 def
Common most human def
105.
C3
Central pivot point and key intermediate of all pathways
106.
C3 def
Severe recurrent infections,glomerulonephritis,most potent or severe
107.
C4
Part of C3 concertase
108.
C4b2a3b( classical) / C5 convertase C3bBb3b(alternative)
*Anti dsDNA abs Anti sm( smith) abs *Rheumatoid factor that targets Fc portion of another antibody( IgM against the Fc portion of IgG) *Antibodies against insulin or beta cell( produces insulin) *anti parietal cell antibodies
Pernicious Anemia
Autoimmune Hemolytic Anemia
Hashimotos Thyroiditis
Cells of the stomach that produces HCL and Intrinsic factor for the absorption of vitamin b12
*anti TSH receptor abs or anti TSIg Graves disease
Goodpasteure Syndrome
CREST
*anti centromere abs
Addisons diseas
* abs to adrenal gland
MS
*anti myelin sheath abs
Myasthenia gravis
*anti acetylcholine receptor abs *anti mitochondriL antibody *anti smooth muscle antibody
Primary biliary cirrhosis
*antibodies to platelets
Chronic active hepatitis ITP 83.
Autoantigen/ autologous antigen
Hosts own antigen
84.
Autologous
donor and recipient are the same person
109.
C4b2a(classical)/C3bBb(alternative) C3 convertase
110.
C5-8 def
Neisseria infection
111.
C8
Starts spore formation in membrane
112.
C9
132.
Complement activation
Not associated with decreased cell susceptibility to phagocytosis
133.
Complement binding site
Ch2 for IgG, ch3 for IgM
134.
Inhibition of hemolysis
Polymerizes to cause lysis
Complement fixation test
135.
Complex(unique)
More immunogenic
136.
Component therapy the transfusion of the specific blood component needed by a patient used primarily to treat anemia or blood loss and insufficient coagulation proteins or platelets to provide adequate hemostasis.
113.
Calcium
C1qrs
114.
Calor
Heat production
115.
CALOR(unit of heat production)
Heat production
116.
CD2
Sheep rbc receptor ( forms rosettes)
117.
CD2
Rosette formation with sheep RBC
137.
Concanavaline A Activates T cells Phytohemagglutinin
118.
CD3
Mature T cells,antigen receptor
138.
Constant region of Ab
Located in the carboxy terminal end
139.
Covalent interaction 1
Does not included
140.
CPDA-1
35 days
141.
CPDA-2 Additive solutions
42 days
142.
Cross reactivity
Phenomenon where some abs secreted one plasma cell can bind a similar but not identical epitope. Although an ab may react with a similar ag, the binding strength differs
143.
CRP
Most potent APR(more than hundred times increase)
119.
CD4
Helper cells(2/3)
120.
CD4:CD8 ratio (HIV)
1:2(reversed) targets T helper cells( CD4 needed by the virus to penetrate inside the cell)
121.
CD8
Cytotoxic and suppresor cells(1/3)
122.
cesium/cobalt
Use in irradiating blood components
123.
Chemotactic agents
C3a,C5a
124.
Chemotaxis
Directed movement of phagocyte towards chem stimulus
144.
Davidsohn differential heterophile antibody test
Forsmann abs( absorbed by GUINEA PIG KIDNEY CELLS) IM SERUM SICKNESS
125.
Chido/Rodgers
Located in C4A and C4B in chromosome 6
145.
DCe
Prevalent Rh phenotype in Asian
146.
DCe
Common in chinese
147.
Dce
Prevalent in Blacks
148.
Dce
Common in Black american
149.
Decreasing osmolality of solution
Deglycerolization of RBCS
150.
Dendritic cells
Most effective APC
151.
Density Gradient Centrifugation Using FicollHypaque (Top to bottom after centrifugation) Plasma Mononuclear cell Ficoll hypaque Rbc and granulocytes
Lymphocyte harvesting
126.
127.
CIE
Classical pathway
Antisera and patients serum move towards each other when electric current is applied IgG or IgM activators, (pinakamatinde)
128.
Colton
Resides in CHIP
129.
Complement
Required for RBC lysis
130.
Complement
Set of 14 -20 serum proteins,beta region(serum protein electrophoresis)
131.
Complement activation
Nota associated with decreased cell susceptibility to phagocytosis
Dia and Dib
Located in Anion exchange molecule (AE-1)
180.
Gamma interferon
Immunoregulation,aka IMMUNOINTERFERON,activated by T CELLS
Disseminated vasodilation
Hypersensitivity reaction
154.
DOLOR
Pain( nerves)
181.
Gamma region
Where antibody reside after serum electrophoresis
155.
Double Negative stage (1)
No cd4 and cd8( walang pangarap kasi bata)
182.
Ge (-2-3-4)
Leach phenotype; elliptocytosis
183.
Gel tech Advantage
Standardization
Double Positive stage(2)
Cd4 and cd8 positive( nag aral ng elem gusto lahat)
184.
Gibson
ACD discoverer
185.
Group AB RH NEGATIVE WITH NO HISTORY OF PRIOR TRANSFUSION needs FFP
Group AB,RH POSITIVE
157.
Double spurs
Non identity
158.
DR 3
SLES, Autoimmune thyrod disease, Dermatitis Herpetiformis
159.
DR 4
Rheumatoid arthritis
186.
Group A individuals
Acquired B happens to
160.
Eosinophil
Suppress inflammatory responses
187.
Group O
Anti a anti b and anti ab
161.
Epitope
Antigenic determinant
188.
Group O and Group B
Acquired A happens to
162.
ESR
Non specific indication of inflammation
189.
Haptens
163.
Exogenous antigens
Antibodies will function more effectively
Not immunogenic by themselves but can be immunogenic when coupled with a high molecular weight substance
164.
Factor B
Binds c3b to form c3 convertase
190.
HBeAg
Marker for hepatitis B infections
165.
Factor D
Cleaves factor B
191.
HBsAb
166.
Factor VIII
Expiration time pf components in FFP is based on
Not required for testing donor's unit
192.
Hct
38%
Kinetic,single immnunodiffusion
193.
Hemoglobin
12.5g/dL
194.
Heparin
Anticoagulant for cardiopulmonary bypass
195.
Hepatitis C
Associated with hepatocellular carcinoma and cirrhosis
196.
Hepatitis G
Frequently occurs as a coinfection with hepatitis C
197.
Hereditary spherocytosis Southeast asian ovalocytosis Congenital acanthocytosis
Mutation in AE-1
198.
HES
Increase separation of RBCs and WBCs
199.
Heterologous antigen
Causes cross reaction
200.
Higher dosage
More immunogenic
201.
Hinge region
Found between Ch1 and Ch 2
152. 153.
156.
167.
Fahey
168.
False The specimen is refrigerated prior to serum negative cold separation agglutinin test
169.
Fc
WBC Bingding site
170.
Febrile reactions
Reduction of cytokines and leukocytes prevent
171.
Fibrin glue
1-2 units of cryoprecipitate + thrombin
172.
Fibroblast
Repair( kung broken ka kailangan mo to para maghilom ang sugat ng nakaraan ) walang forever haha jk
173.
First line of defenses
Unbroken skin Normal flora Secretions
174.
Fisher-Race
3 closely linked genes
175.
Forward
Ag
176.
Fresh Frozen Plasma
If the unit is in the low volume range (300404 mL) what component must NOT be made?
202.
Hinge region
Between ch1 and ch2
177.
FTA ABS ABsorbent
Reiter treponeme
203.
HLA
Molecular basis for T cells to discriminate self from nonself
178.
FUNCTIO LAESA
Loss of function
204.
HLA B27
Marker for Ankilosing Spondilitis/Arthritis Spondylitis
179.
Fy6
Important in invasion of P. vivax
205.
HLA B 27
Ankylosing spondylitis, Bomboo Spine Disorder
206.
HLA CLASS 2
T helper cell
207.
HLA class 2
B cell
208.
Homologous Induces antibody and reacts specifically with antigen it
209.
hr"
e
210.
hr'
c
211.
Hybridoma
Cells that have the ability to reproduce indefinitely and synthesize antibodies ( cancer cell plus B cell) MAY FOREVER SA HYBRIDOMA
212.
IgA dimeric
Predominantly found in secretions,contains secretory component that protects is when in the body secretions
213.
IgA monomeric
Predominantly found in blood
214.
IgD and IgM
Surface Igs on B cells
215.
IgE
Binds basophils,mast cells leading to allergic reaction but when binds to eosinophil can used as anti helminthic
216.
IgG
Warm reactive
217.
IgG1
Most efficient in crossing the placenta
218.
IgG 2
Cannot cross or weak in crossing the placenta
219.
IgG3
Mos efficient in activating complement
220.
IgG4
Do not activate the complement
221.
IgM
222.
237.
Immune mediated NHTR
More common in women Occurence: 1:200 units
238.
Immune organs
Lymph,spleen,bone marrow,thymus,appendix,lymphoid
Immuniti against HEPA B virus
Anti HBsq
240.
Immunization
Generating protection against disease by administering antigen( vaccination)
241.
Immunogens
Antigens that can stimulate the adaptive immune response
242.
Immunohematology
academic knowledge and procedures involving the study of the immunologic responses to blood components.
243.
Indefinite/ permanent
Tegison
239.
244. Interleukins(
cytokines)
Messenger proteins or signal molecules,produced by WBCs
245.
Intradermal>subcutaneous Antigenecity degree or IM
246.
Ionic bonds and Hydrogen Hydrophilic reaction bonds 1
247.
IV AND IP
Effective
248.
Jk(a-b-)
Found in polynesians, japanese, indonesians, chinese, filipinos
Cant cross the placenta
249.
K0K0
Kell null phenotype
IgM
Cold reactive
250.
Kell
223.
IgM
Most potent activator
2nd most immunogenic blood group system next to Rh
224.
IgM
Most efficient in agglutination,can bind up to 10 same antigens, effective also in complement activation,natural antibodies in the ABO category,primary response antibody
251.
Kupffer cell
Liver macrophages
252.
Le(a+b-)
Lele, sese in secretions
253.
Le(a+b+)
Intermediate to Lewis positive, secretor
225.
IgM and IgA j chain
254.
Leukopheresis
Not more than twice a week
226.
IgM and IgE
They are the only ab that have an extended constant heavy chains
255.
Lewis
No HDN cant cross the placenta
IgM and IgG
Can only activate the complement
256.
Lewis antibodies
227.
Neutralized bu pooled human sera
228.
IgM IgD
Found in surface of circulating Bcells
257.
Lewis antigen
Absorb in the plasma by red cells
IL1
Fever( proinflammatory)
258.
230.
IL 3
Mutlti colony stimulating factor
Lewis blood group system(formation from birth to adult)
(a-b-)(a+b-)(a+b+)(a-b+)
229.
231.
IL 3
Multi colony stimulating factor
259.
LISS
232.
IL 3
Multicolony stimulating factor( stimulates proliferation of numerous cells)
10-15 minutes KAILANGAN NILA NG TIME TO GET TO KNOW EACH OTHER
233.
IL6
Increases CRP level
260.
LocLized vasodilation
Primary response to acute inflammation
234.
IL12
Activates NK CELLS
261.
Louis Pasteur
Father of Immunology
235.
Immature B cell
CD 19,CD24,CD45R, IgM molecules on the surface,CD21,CD40,MHC class II
262.
Loutit and Mollison
ACD was invented by
236.
Immediate spin +
IgM
263.
LPS
Activates B cells
264.
Lysis
Ultimate goal of complement activation
265.
Lysosomal enzymes
Lactoferrin,lysozymes,defensins
266.
Mature B cell
CD 19,CD24,CD45R, IgM and IgDmolecules on the surface,CD21,CD40,MHC class II
267.
Mature T cells(3)
Cd4 or cd8 positive ( nagcollege kailangang pumili lang ng isang kurso) hindi practikal pag gawin mo lahat kailangan mong magdesisyon ng tama at isa. puwede kanang sumabak sa totoong laban ng buhay. Exposure though. Hehe
268.
MBL Pathway
Activation occurs when there is presence of mannose in the bacterial surfaces
269.
MHC
Chromosome 6 short arm, codes for HLA
270.
MHC CLASS I
All nucleated cells,presents antigento CD8 positve cells
271.
MHC CLASS II
Found in B cells, Macrophages and Neutrophils,presents antigen to CD 4 positive cells
272.
MHC CLASS III
No role in antigen presentation
273.
Missing abs
Type l
274.
MN SYSTEM
Sialoglycoprotein
275.
Molecules with repeating units
Less immunogenic
Monoclonal Antibodies
Are not frequently occuring in nature
Mother with Group A with anti D in serum,best for intruterine transfusion?
O Rh Negative irradiated RBCS
276.
277.
278.
NSugar attached to L-fucose in type A acetylgalactosamine individuals
279.
Natural active
Natural exposure to antigen( disease process)
280.
Natural immunity
Innate or inborn
281.
Natural passive
Natural exposure to antibody ( transplacental transfer of antibody to the fetus, IgG, colostrum IgA)
282.
283.
Neocytes
Neocytes
To avoid hemochromatosis/ hemosiderosis/ iron overload what mus be transfused to the patient? Young RBCs used in patients with thalassemia
284.
NK
Kills infected cells that harbors the microorganism inside it; lymphocytes(third population);NULL cells;5-15 % total lypmhocyte population;CD 16,56; kills viruses(targets primarily the viralenveloped proteins) and tumor cells even without sensitization by releasing PERFORINS
285.
NK cells
5-15 percent
286.
Non A-G hepatitis
Post transfusion Hepatitis
287.
None; but Kidd Major sequelae of Delayed HTR may cause major delayed hemolysis
288.
None; provided the donor is symptom free and afebrile
Deferral for toxoids, killed or synthetic vaccines
289.
Normal CD4:CD8 ratio
2:1
290.
Nutricel
AS-3
291.
One light chain and one half heavy chain
Antigen binding site
292.
Opsonins
C3b,CRP,Ig
293.
PAMP
Where pattern recognition receptors bind
294.
Papain
Three fragments
295.
Papain
3 fragment of antibodies
296.
Paratope
Antibody determinant
297.
Passive
Antibody exposure
298.
Paul bunell test
Positive or negative only
299.
PCR
Molecular approach
300.
PEG (polyethylene Enhances interaction of antigen glycol) antibody reaction
301.
Pepsin
Stomach( chief cells) targets peptides
302.
Pepsin
Two fragments
303.
Plasma cell
Synthesize antibody
304.
Plasma cell
Produces Antibody
305.
Plasmapheresis
Every 4 weeks
306.
Plateletpheresis Leukopheresis
24 times per year
307.
Pokeweed mitogen
Activates B and T cells
308.
Postzone Antigen in excess, so insufficient Phenomenon(false reactive sites on antibody for lattice negative) formation
309.
Pre B cell
CD 19,CD24,CD45R, mu chains in cytoplasm
310.
Precipitation
Soluble antigen with soluble antibodies
311.
Precipitation 2
Particulate antigen
340.
RUBOR
Redness
312.
Presumtive Heterophile antibody test positive
Agglutination
341.
Sebum,lactic acid,fatty acids
Found in the skin
342.
Antibody titer shoul be HIGHER
313.
Private
Unique to an individual or family
314.
Pro B cell
CD 19,CD24,CD45R
Secondary anamnestic response
315.
Proline
Found in the Hinge region,reponsible for its flexibility
343.
Antibody titer should be HIGHER
316.
Properdin
Stabilizes the c3bBb
Secondary anamnestic response
344.
Sensitivity
317.
Proteins> Polysaccharides> Lipids and Nucleic acid
Degree of immunogenecity
Ability to be positive in the presence of its homologous antigen
345.
Sensitization
Aka COATING
346.
Specificity
Prozone Phenomenon(false negative)
Antibody in excess, so insufficient reactive sites on the antigen for lattice formation
Ability to be negative in the presence of homologous antigen
347.
Stages of agglutination
1. Sensitization/ Coating 2. Lattice formation
319.
Public antigen
Found commonly in about 98% of population
348.
320.
Pulse
80/100
Stages of complement activation
Recognition Activation MAC
321.
R1r
Most common Rh positive phenotype
349.
Streps in HYBRIDOMA TECHNOLOGY
322.
R1/r2
Most common in blacks
323.
Rare blood type
frozen rbc up to 10 yrs.
324.
Ratio of kappa and lambda
2:1
325.
RBC
universal
326.
Reactive oxygen intermediated
Superoxide anion,h2o2,hydroxyl radicals
327.
Reaginic Antibody
Former name of IgE
1. Immunize the mouse with the antigen of interest 2. Removal of spleen from the mouse 3. Removal of RBCs from the spleen cells 4. Fusion of spleen cells with the myeloma cells 5. Put cell mixture in the medium HYPOXANTHINE-AMINOPTERINTHYMIDINE 6. Identify hybridoma cell that produces the antibody of interest.
328.
Red cellpheresis
Every 16 months
329.
Reverse
Ab
350.
B cell surface markers
330.
Reversible
Antigen antibody reactions WALANG FOREVER MAGHIHIWALAY DIN SILA
Surface Ig Fc receptor C3 receptor
351.
Svedberg
Sedimentation rate of Immunoglobulins
318.
LL, MM, LM(hybridoma cell)
331.
rh'
C
352.
T cell
60-80 percent
332.
rh"
E
353.
Temp
37C highest
333.
RHD RHCE
Genes that control Rh activity
354.
Terumo corp
Optisol
355.
Th1
Against intracellular antigens
334.
Rh null
---/---
356.
Th2
Against extracellular antigens
335.
Rho
D
357.
Therapeutic
336.
Rhogam (RhIg) contain anti D antibodies
Prevention of HDN (agains D antigen)
removal of a blood component to alleviate the symptoms caused by an underlying disease.
358.
Thymus
337.
Rouleaux formation
Stacked coin appearence add NSS do disperse reaction
Organ that atrophied as one ages,butterfly shape organ
359.
TNF
Effective agains gram negative
338.
RPR
Serum is no longer heated thus called rapid test
360.
Toxoids
Originally toxins that were made to become non toxic
339.
rr
Most common Rh negative phenotype
361.
TPI
Livinf treponema pallidum
362.
TRALI FNHTR
Anti-leukocyte antibody
363.
Transfusion medicine
medical practice and techniques associated with replacement of RBCs and blood components.
364.
Transfusion related sepsis
Platelet concentrate( because it is stored at room temperature)
365.
Transfusion transmitted Virus
Torque Teno Virus
366.
True Agglutination
Remains intact after dispersing NSS
367.
TUMOR
Swelling( because of basophils promoting vasodilation): instant access of cells
368.
Type 2
Precursor chain for RBC; Beta(1,4) linkage; Glycoproteins, Glycolipids, Glycosphingolipids
369.
Type ll Type of hypersensitivity reactions HDN
370.
Type of Allergic reactions hypersensitivity Hay fever reactions Asthma Type l
HDN Post transfusion hemolytc reaction Autoimmune hemolytic anemia
Tye ll
SLE RHEUMATOID ARTHRITIS Arthus reaction Serum sickness
Type lll Tuberculin injection Contact dermatitis
Type lV 371.
Van Der Waals Force 1
Hydrophobic reaction
372.
Variable domains
Occur in the both heavy and light chain
373.
Variable region of Ab
Located in the amino terminal region
374.
Vasodilation
Primary response to acute inflammation
375.
Vasodilation
Primari response to acute inflammation
376.
Vicea graminea
Lectin source pf Anti-N
377.
Weight
50kg/110lbs
378.
Weight, Height, Hematocrit
Double RBC pheresis requirements
379.
Whole blood
same blood type
380.
Zone of Equivalence(+)
Most antibody is precipitated by the least amount of antigen
