Preparation of Sulfanilic Acid

 Name:

Trixie Babes Capio

Date of Experiment: Sept. 30 –Oct 4, 20!

"ab #artner:

Dina "acson

Date of S$bmission: Oc October %, 20!

&astin Da'e Estan(arte

S)NT*ES+S O S-"N+"+C C+D Experiment No. !

/ES-"TS ND D+SC-SS+ON S$faniic aci( 14minobenenes$fonic aci(, C!* NO  NO3S, is one of t5e most important inte interm rme( e(ia iate tess mate materi ria as. s. +t is main main6 6 $se( $se( in (6es (6es an( an( bri7 bri75t 5ten ener ers. s. S$f S$fan ani iic ic aci( aci( is 85ite to 7ra6 po8(er t5at is si75t6 so$be in co( 8ater. S$faniic aci( is aso con'erte( to s$fa (r$7s, cae( s$faniami(e, s$faniami(e, one of t5e eariest s6nt5etic antibiotics $se( to treat bacteria infection.

i7$re . S$faniic ci( To prepare s$faniic aci(, aniine 8as s$fonate(. niine is an or7anic compo$n( 8it5 t5e form$a C!*9N*2. +t is benene 8it5 an amino 7ro$p attac5e( to it. Benene is a stabe compo$n( 5o8e'er 8it5 t5e amino 7ro$p present, its reacti'it6 increases. T5is 5i75 reacti'it6 is  bro$75t b6 t5e amino 7ro$p. +t is an acti'atin7 7ro$p 7 ro$p or eectron(onor, (onatin7 eectrons to t5e rin7 t5at increases t5e abiit6 of t5e rin7 to react to eectrop5ies. T5is 5i75 reacti'it6 (ri'es t5e reaction of s$f$ric aci( to aniine.

i7$re 2. /eaction of niine an( S$f$ric ci( to pro($ce S$faniic ci(.

-ni;e ot5er eectrop5iic s$bstit$tion, t5is s$fonation process in'o'es reaction of t5e *SO4 at t5e basic amino 7ro$p. T5e pro($ct m$st t5en be 5eate( $pto %0
i7$re 3. Ort5o, =eta an( #ara attac;s in niine

To reco'er t5e s$faniic aci(, it 8as precipitate( b6 a((ition of t5e cooe( so$tion to cr$s5e( ice. T5e experimenters 5a'e s$ccessf$6 reco'ere( t5e precipitate 5o8e'er fitration 8as con($cte( b6 t5e next meetin7. B6 t5e time of fitration, t5e precipitate 8as (isso'e( bac;  to t5e so$tion. T5e so$tion 8as 5eate( a7ain an( pace( into co( bat5 to precipitate t5e s$faniic aci( ass$min7 t5at t5e reaction is re'ersibe. fter 5eatin7 an( ice bat5 5o8e'er, t5e  precipitate (i( not appear. +f reco'ere( t5e cr$(e 8i be (ecoorie( $sin7 acti'ate( c5arcoa. >Coor? 8as consi(ere( as imp$rit6 so t5e acti'ate( carbon absobs ar7e coore( moec$es present re($cin7 t5e 6ie(. T5e precipitate 8as aso p$rifie( b6 recr6staiation to form a cr6staine s$faniic aci(.

CONC"-S+ON T5e experiment (i( not 6ie( an6 pro($ct since t5e precipitate 8as (isso'e bac; into t5e so$tion. Consi(erin7 t5at t5e s$fonation reaction of t5e compo$n( 8as a re'ersibe reaction (es$fonation co$( occ$r an( s$fonation it bac; ma6 aso ta;e t8o to t5ree 5o$rs of 5eatin7 time 85ic5 8as (iffic$t to ac5ie'e t5e time of experiment since t5e time 7i'en 8as on6 an 5o$r  to t8o. Ot5er errors co$( be in;e( to t5e errors in meas$rin7 t5e startin7 materias, incompete reactions, an( pro($ct oss ($e to t5e proce($re an( stora7e of t5e so$tion.

/EE/ENCES

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Smit5, &.@. Or7anic C5emistr6. =c@ra8*i: Ne8 )or;, 20. 3r( E(ition. =c=$rr6, &. Or7anic C5emistr6. Ce7na7e "earnin7: -S, 200. %t5 E(ition. S$faniic ci(. Can75o$ "in7an7 )$e7$o C5emica Co., "t(.5ttp:AA888.6

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7c5em.com.cn 1(ate accesse( Oct 9, 20! niine. T5e C5emo$rs Compan6.5ttp:AA888.c5emo$rs.com 1(ate accesse( Oct 9,

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20! exan(er, E. S$fonation Of mines it5 $min7 S$f$ric ci(. T5e Con'erse

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=emoria "aborator6 Of *ar'ar( -ni'ersit6. 14!