DRUG STUDY DRUG Penicillin G Benzathine
(Penadur)
CLASSIFICATION
Anti-infective, Antibiotic
MECANISM OF ACTION
INDICATION
CONTRAINDICATION
SIDE EFFECTS
NURSING RESPONSIBILITY
CNS: Lethargy, Interferes with Severe infections Concentrations Before bacterial cell wall caused by sensitive - Allergies to penicillins,hallucinations, - Observe 15 rights of drug synthesis during organisms cephalosporins, or otherseizures administration. active (streptococci) allergens - Reduce dosage with hepatic or GI: Glossitis, multiplication, - URTI caused by renal failure. causing cell wall sensitive stomatitis, gastritis, - Assess for hypersensitivity to drug. Precaution sore mouth, furry - Assess for any contraindications to death and resultant streptococci - Renal disorders tongue, black bactericidal activity - Treatment of - Pregnancy the drug. ³hairy´ tongue, against susceptible syphilis, bejel, - Lactation - Educate about side effects of drug. nausea, vomiting, During bacteria. congenital syphilis, diarrhea, abdominal pinta, yaws - Drug is not for IV use. Do not Drug interaction pain, bloody inject or mix with other IV - Prophylaxis of Drug to drug rheumatic fever and - Decreased effectiveness diarrhea, solutions. chorea with tetracyclines enterocolitis, - Give IM injection in upper outer - Inactivation of parenteral pseudomembranous quadrant of the buttock. aminoglycosides colitis, nonspecific - Avoid contact with the needle. (amikacin, gentamicin, hepatitis - Withdraw needle as quickly as kanamycin, neomycin, GU: Nephritis possible to avoid discomfort. tobramycin) - Stay with patient throughout whole Hematologic: duration of administration. Anemia, Drug to food thrombocytopenia, After - Monitor client for at least 30 - none reported leukopenia, minutes. neutropenia, prolonged bleeding- Arrange for regular follow-up, itme including blood tests, to evaluate Hypersensitivity: effects. Rash, fever, - Instruct to report difficulty wheezing, breathing, rashes, severe pain at injection site, mouth sores, unusual anaphylaxis bleeding or bruising. Local: Pain, - Instruct to take medication as phlebitis, thrombosis
at injection site, directed for the full course of Jarisch-Herxheimertherapy, even if feeling better. reaction when used to treat syphilis
