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Pathways Hipertensi
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Pathways Hipertensi
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Sri Kuspartianingsih
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19 B. Pathways Hipertensi (Price & Wilson,1995) Volume cairan ekkstraselular
Tekanan perfusi ginjal
Na+ tubuh
Peregangan afferent arteri glomerulus
Na+ macula dens tubulus ginjal
Stimulus juxtaglomerulus (apparatus) rennin Angiotensinogen
Angiotensin I Angiotensin II
Pembuluh darah
Stimulus korteks adrenal
Tekanan darah
Produksi aldosteron Volume cairan extracellular
Tek arteri
Beban kerja jantung
Sclerosis ssistemik
Kontraksi vena
Bood clot &
Fungsi vascular
Trombosis/pecahnya Trombosis/pecahnya vascular
Ventricle hypertensi Elastisitas ventricle
Perdarahan cerebrum Kontraktilitas ventricle
Lesi jar cerebral
Cardiac Output
Jaringan
Reabsorbsi H+
O2 & CO2
Nousea-vomitus Nutrisi < kebutuhan
Nyeri kepala
ekserbasi
stroke
Sal cerna
Korosi sal cerna
Perdarahan ginjal
ginjal O2 & CO2
Metabolisme anaerob Stimulus peka nyeri kapiler
otak
jantung
otot
Beban jantung
Ang.T I & II Vaso kontriksi vascular Mengekspesikan HT myalgia
kelemahan
Dekom cordis
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