Pathology 2009-2010 MBBS MCQs 1. Fibrocystic changes a) is the most most commo common n breast breast disord disorder er in women women b) is due to abnor abnormal mal respons response e to ovarian ovarian hormo hormones nes c) is associated with in-situ carcinoma d) has high high risk risk of develop developing ing breast breast canc cancer er e) is also also know known n as fibroade fibroadenoma noma.. 2. Endometrial cancer is a) associated associated with use of intrauterine intrauterine contraceptiv contraceptive e device device b) associat associated ed with with excess excess estro estrogen gen c) obesi obesity ty as as a risk risk fact factor or d) clear clear cell cell CA is the the most most commo common n e) associat associated ed with HPV infectio infection n 3. In the area of molecular pathology and molecular diagnosis, a) The detection detection of monoclona monoclonality lity is essential essential in diagnosing diagnosing biopsy biopsy samples samples of breast cancer. b) Microsomal Microsomal instability instability are helpful helpful in diagnosin diagnosing g HNPCC HNPCC c) The detection detection of monoclona monoclonality lity is essential essential in diagnosing diagnosing biopsy samples samples of lymphomas d) HER2-neu HER2-neu gene detection by by FISH test test is used used to diagnose diagnose inherited inherited breast breast cancer e) FAP is caused caused by by mutations mutations in the mis-match mis-match repair genes. genes. 4. Granulomas a) are mainly mainly compose compose of macrophage macrophages, s, epitheloid epitheloid cells and and lymphocytes lymphocytes b) are always always cause caused d by infectio infections ns c) are mediated mediated by CD4+T CD4+T lympho lymphocyte cytes s d) are mediated by IL-2 and alpha IFN e) always contain area of central necrosis 5. The sequence of metaplasia-dysplasia-neoplasia occurs in the neogenesis of a) squamous cell carcinoma bladder b) carcinoi carcinoid d of the small small intest intestine ine c) adenoca adenocarcin rcinoma oma of of the Barret Barret's 's oespha oesphagus gus d) squamous cell carcinoma of the lungs e) malig maligna nant nt lympho lymphoma ma 6. In acute inflammation a) decrease decreased d blood blood flow to to affect affected ed part part b) increase increased d vascular vascular permea permeabilit bility y to proteins proteins c) is associated with local 5 hydroxytrytamine release d) caused caused by mechan mechanical ical trauma trauma e) a manifestation of the ability of normal tissues to respond to damage
7. Regarding Osteoarthritis a) cartil cartilage age fibril fibrillat lation ion b) pannus formation c) ebur eburna nati tion on of bone bone d) herbe herberd rden' en's s nodes nodes e) osteophyte formation 8. Macrophages a) play a role role in in graft graft rejectio rejection n b) are involve involved d in antig antigen en recog recognitio nition n c) Have membrane membrane receptors receptors for Fc Fc fragment fragment of antibodies antibodies d) Is involv involved ed in type 4 hyperse hypersensit nsitivit ivity y e) Have Have no phagocy phagocytic tic properti properties es 9. Low grade lymphomas: a) Incu ncurabl able b) monoclo monoclonal nal prolifer proliferatio ation n of large lympho lymphoid id cells c) clinic clinicall ally y aggre aggress ssive ive 10. 11. Which of the following helps in the grading of a tumor? a) the presence or absence of metastases in the lymph node b) the degree degree of diff differen erentiat tiation ion c) the presence presence of tumo tumorr necro necrosis sis d) mito mitoti tic c acti activi vity ty e) the prese presence nce of cells cells in the vascu vascular lar space spaces s 12. Successful healing of long bones depends upon: a) appos appositi ition on of the the fragm fragmen ents ts b) Surgica Surgicall remova removall of the the hema hematoma toma c) Free Free mob mobili ility ty of of the the limb limb d) The The abse absence nce of infe infecti ction on e) Eleva Elevatio tion n of of the the lim limb b 13. Small cell carcinoma of the lung is: a. Is not assoc associate iated d with cigarett cigarette e smokin smoking. g. b. Is usuall usually y found found in the peripher periphery y of the lung lung.. c. Is more more common common in women women than men. men. d. Often Often prod produces uces ectopic ectopic hormone hormones s e. Has Has a poor poor progn prognos osis. is. 14. Adult respiratory distress syndrome: a) pulmonar pulmonary y edema edema is a feature feature b) hyaline membrane is present in alveoli
c) has has a hig high h mor morta tali lity ty d) associated with acute pancreatitis e) can occur occur follow following ing diffu diffuse se alveola alveolarr injury injury 15. 16. Fall in blood pH from 7.40 to 7.10 a) represents represents an approximate approximate doubling doubling of H+ concentration concentration b) characte characterist risticall ically y caused by persiste persistent nt vomiting vomiting c) characte characterist risticall ically y caused caused by hyperven hyperventila tilation tion d) can be accomp accompanie anied d by elevated elevated serum serum potassium potassium e) is inco incompa mpatib tible le with with life life 17. What of the following causes elevated total CSF protein: a) CNS tu tumour our b) CVA c) Epilepsy d) Viral iral men menin ingi giti tis s e) CNS tra trau uma 18. H Pylori a) associat associated ed with gastric gastric carcino carcinoma ma and lymphom lymphoma a b) causes causes a chroni chronic c lymphoid lymphoid infiltra infiltration tion c) is a urea-producing organism d) is usually usually found found in areas areas of of intestin intestinal al metapla metaplasia sia e) causes a chronic chronic gastritis gastritis by invading the mucosal mucosal epithelium epithelium 19. Pseudomembranous Colitis a) caused by clostridium difficile toxin b) is present present in immunos immunosuppr uppresse essed d individua individuals ls c) toxin mediated mediated injury causes epithelial epithelial shedding shedding and and necrosis necrosis d) pseudomembrane pseudomembranes s present present by desloughi desloughing ng of of epithelium epithelium e) associat associated ed with antibiot antibiotic ic use 20. Concerning SLE a) circulating circulating immune immune complexes complexes responsible responsible for glomerulonephrit glomerulonephritis is b) absolute absolute increa increase se in T supp suppress ressor or cells cells c) renal renal biopsy biopsy seldom seldom required required for for directing directing therap therapy y d) renal biopsy biopsy includes includes active diffuse diffuse proliferating proliferating glomerulone glomerulonephritis phritis e) ITP can be be initial initial mani manifesta festation tion of SLE SLE Please feel free to contact for further data of fallowing u niversities Fees, admission, classes, environment http://pakdata.net
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National Defence University University,, Islamabad Virtual Vi rtual University of o f Pakistan, Pakistan, Lahore National University of Science and Technology Technology,, Rawalpindi Quaid-e-Azam University, University, Islamabad Pakistan Institute of Development Economics, Economics, Islamabad Pakistan Institute of Engineering & Applied Sciences, Sciences, Islamabad National University of Modern Languages, Languages, Islamabad International Islamic University, University, Islamabad Institute of Space Technology (IST), Islamabad Federal Urdu University of Arts, Science and Technology, Technology, Islamabad and Karachi COMSATS Institute of Information Technology, Technology, Islamabad Bahria University, University, Islamabad Allama Iqbal Open University, University, Islamabad Air University, University, Islamabad Riphah International University, University, Islamabad National University of Computer and Emerging Sciences, Sciences, Islamabad Foundation University, University, Rawalpindi Center for Advanced Studies in Engineering, Engineering, Islamabad University of Azad Jammu and Kashmir , Muzaffarabad Mohi-ud-Din Islamic University, University, Nerian Sharif AJK Al-Khair University (Mir Pur AJK), AJK), Bolan University of Medical & Health Sciences, Sciences, Quetta Balochistan University of Engineering and Technology Technology,, Khuzdar Balochistan University of Information Technology Technology,, Engineering and Management Sciences,, Quetta Sciences Lasbela University of Agriculture, Water Water & Marine Science, Science, Lasbela Sardar Bahadur Khan Women University, University, Quetta University of Balochistan, Balochistan, Quetta Institute of Management Sciences (IMSciences), Hayatabad Frontier Women University, University, Peshawar Gomal University, University, Dera Ismail Khan Islamia College University, University, Peshawar Kohat University of Science & Technology echnology,, Kohat Khyber University of Medical and Health Sciences, Sciences, Peshawar NWFP Agricultural Agricultural University University,, Peshawar Pakistan Military Academy, Academy, Abbotabad The University of Science & Tecnology Tecnology,, Bannu University of Engineering and Technology (NWFP), (NWFP), Peshawar University of Hazara, Hazara, Hazara University of Malakand, Malakand, Chakdara University of Peshawar , Peshawar Qurtaba University of Science & Information Technology Technology,, D. I. Khan, Khan, Peshawar CECOS University of Information Technology and Emerging Sciences, Sciences, Peshawar City University of Science and Information Technology, Technology, Peshawar Gandhara University, University, Peshawar
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Ghulam Ishaq Khan Institute of Engineering Sciences and Technology Technology,, Swabi Northern University, University, Nowshera Preston University, University, Kohat Sarhad University of Science and Information Technology Technology,, Peshawar Abasyn University, University, Peshawar Gandhara College of Arts, Arts, Peshawar Karakurum International University, University, Gilgit Allama Iqbal Open University, University, Gilgit Bahauddin Zakariya University, University, Multan
King Edward Medical University, University, Lahore • •
Fatima Jinnah Women University, University, Rawalpindi Government College University, University, Lahore
Lahore University of Management Sciences • • • • • • • • • • • • • •
Government College University University,, Faisalabad The Islamia University of Bahawalpur , Bahawalpur Kinnaird College for Women Women,, Lahore King Edward Medical College, College, Lahore Lahore College for Women Women University, University, Lahore National College of Arts, Arts, Lahore National Textile University, University , Faisalabad University of Agriculture, Agriculture, Faisalabad University of Arid Agriculture, Agriculture, Rawalpindi University of Education, Education, Lahore University of Engineering and Technology, Technology, Lahore, Faisalabad University of Engineering and Technology, Technology,Taxila University of Health Sciences, Sciences, Lahore University of Gujrat, Gujrat, Gujrat
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University of the Punjab, Punjab, Lahore, Gujranwala University of Sargodha, Sargodha, Sargodha University of Veterinary and Animal Sciences Sciences,, Lahore Virtual Vi rtual University of o f Pakistan, Pakistan, Lahore Hajvery University, Lahore Beaconhouse National University, University, Lahore Forman Christian College, College, Lahore GIFT University, University, Gujranwala Imperial College of Business Studies, Studies, Lahore Institute of Management Sciences, Lahore, Lahore, Pak-AIMS Pak-AIMS,, Lahore Lahore School of Economics, Economics, Lahore Lahore University of Management Sciences, Sciences, Lahore Minhaj International University, University, Lahore National College of Business Administration Administration and Economics, Economics, Lahore School of Business & Commerce, Commerce, Rawalpindi University Of Management and Technology, Technology, Lahore University of Central Punjab, Punjab, Lahore University of Faisalabad, Faisalabad, Faisalabad University of Lahore, Lahore, Lahore University of South Asia, Asia, Lahore Superior University, University, Lahore International Islamic University, University, Bahawalpur University College Lahore, Lahore, Lahore University of Munawwar-ul-islam.Gujrat Munawwar-ul-islam.Gujrat Bahria University, University, Karachi Campus Dawood College of Engineering and Technology,Karachi Technology,Karachi Dow University of Health Sciences, Sciences, Karachi Institute of Business Administration Administration,, Karachi Liaquat University of Medical and Health Sciences, Sciences, Jamshoro, Hyderabad Mehran University of Engineering and an d Technology, Technology, Jamshoro, Hyderabad NED University of Engineering & Technology Technology,, Karachi Pakistan Naval Academy, Academy, Karachi Quaid-e-Awam Quaid-e-A wam University of Engineering, Science and Technology, Technology, Nawabshah Shah Abdul Latif Bhitai University, University, Khairpur Sindh Agriculture University, University, Tandojam Institute of Business Administration (IBA) Sukkur University of Karachi, Karachi, Karachi University of Sindh, Sindh, Jamshoro, Hyderabad Aga Khan University, University, Karachi Baqai Medical University, University, Karachi Dadabhoy Institute of Higher Education, Education, Karachi DHA Suffa University, University, Karachi Greenwich University, University, Karachi Hamdard University, University, Karachi Indus Institute of Higher Education, Education, Karachi
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Indus Valley Valley School of Art and Architecture, Architecture, Karachi National University of Computer and Emerging Sciences, Sciences, formerly FAST Institute of Computer Science Karachi Campus Institute of Business & Technology (BIZTEK), Karachi Institute of Business Management, Management, Karachi Iqra University, University, Karachi Isra University, University, Hyderabad Jinnah University for Women Women,, Karachi Karachi Institute of Economics & Technology (PAF KIET), Karachi KASB Institute of Information Technology Technology,, Karachi Mohammad Ali Jinnah University, University, Karachi Nazeer Hussain University, University, Karachi Newports Institute of Communications and Economics, Economics, Karachi Preston Institute of Management Sciences and Technology, Technology, Karachi Preston University, University, Karachi Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology Technology,, Karachi Sir Syed University of Engineering and Technology echnology,, Karachi Textile Text ile Institute of o f Pakistan, Pakistan, Karachi University of East, East, Hyderabad Ziauddin Medical University, University, Karachi