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W H A T I S M S M? M?
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Th e MS M Mir a c
T H E D I S C O VE VE R Y OF MSM NATURAL S O U R C ES ES O F MS M MSM AND H UMA UMAN N HEALTH WH Y DO HUMANS NEED
T h e o f fi f i c ia ia l w e b s i t e o f t h e
M S M - Me M e d ic a l I n f o r m a t io n F o u n d a t io n
A n o n - p r o f it it o r g a n i s a t i o n lo l o c a t e d in i n t h e H a g u e , Ne Ne t h e r l a n d (
[email protected])
W H A T I S MS M ?
SULFUR?
Protein Structure Connective Tissue Cell Membrane Permeability Metabolism WH Y DO HUMANS NEED MSM?
MSM is an abbreviation of methylsulfonylmethane, methylsulfonylmethane, an organic form of sulfur. The chemical formula of MSM® is CH3SO2CH3. It is the form in which sulfur appears in nature in all living organisms, and in which it biologically active. MSM is an odorless, white, crystalline powder that highly soluble in hot water and in a wide range of organic solvents (1) Biologically active sulfur has unbelievable preventive and therapeutic properties. The medicinal activities of biological sulfur are so allencompassing, encompassing, and are based on such obvious principles, that its disc is generally considered one of the biggest advances in orthomolecular medicine in the second half of this century.
Preferred Dietary Source of Sulfur THE DI SCOVERY OF MSM Protection of the Mucosa About forty years ago, Dr. Stanley Jacob and Dr. Robert Herschler, ch WHAT CAN MSM with the pulp and paper plant Crown Zellerbach Corporation, were ask find a use for lignin, one of the primary waste products of the plant. D O F O R YO U ? Oxidation of lignin in a reactor was shown to result in the formation o Chronic Pain Synergetic Effect DMSO (Dimethylsulfoxide), a natural, organic form of sulfur. This wat soluble compound has a strong and bitter taste, and is absorbed rapid Antioxidant through the skin. Workers coming in contact with the DMSO-containin Detoxification wastewater, noticed their perspiration began smelling like DMSO, and Neurological tasted its bitterness in their mouths. Moreover, the water appeared to Sign up to vote on this title special medicinal qualities. Many stories about miraculous recoveries a Diseases Useful not Not useful Certain is, benefits still go around, but they can be authenticated. Allergies however, that cuts, scrapes, burns and sprains recovered more quickl Autoimmune when dipped in this water. Several workers also noticed that condition Diseases
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D E TO XI F I C A TI O N (3). Algae and several forms of plankton in oceans are capable of abs SYMPTOMS
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LITERATURE
massive amounts of inorganic sulfur from seawater, and to convert th a simple, organically-bound form. When these algae and planktonic organisms die, enzymatic processes result in the breakdown of the molecules into DMS, or Dimethylsulfide. This compound is volatile and poorly soluble in water. It collects in the stratosphere, where it is oxid under the influence of ultraviolet l ight into DMSO (Dimethylsulfoxide) further converted into MSM (Methylsulfonylmethane). DMSO and MSM highly soluble in water, and therefore concentrate easily in atmospher water vapor, returning to earth in the form of rain. Plant roots rapidly collect and concentrate these sulfur sources. Laboratory research has shown, that a one ppm mixture of radioactive labeled DMSO and MSM concentrate hundred fold in plant roots within hours (4).
Rainwater in particular therefore contains a lot of MSM. It is also abun found in fresh fruit and vegetables in amounts generally ranging from mg/kg (3). Raw milk from cows which graze in pastures contains 2 to mg/kg MSM. Due to the volatile nature of MSM, it is rapidly lost due t heating during the preparation of food. It is also lost when vegetables fruit are left for a period of time, heated or not. Pasturized milk there contains less than 0.25 mg/kg MSM, roughly the same amount as fou milk from cows fed dried, artificial food (3). Due to our present day's dietary patterns, it is unavoidable that modern man suffers from a ch shortage of MSM.
MSM AND HUMAN HEALTH
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The natural level of MSM in the circulatory system of an adult human UnlockNormal full accessadults with a free trial. 4 to 11 mg MSM per day in is about 0.2 mg/kg. excrete urine. Several studies suggest, that the systemic concentration of MS drops in mammals with increasing age, possibly as a result of changin Download With Free Trial or body metabolism. Some research suggests, that there is a minimu concentration of MSM that must be maintained in the body to preserv normal function and structure (8, 9). Low concentrations of MSM in ou bodies have been linked with unspecified complaints of fatigue, depre high sensitivity to physical and psychological stress, and with a large number of degenerative diseases (5, 6). MSM is an important source sulfur, but also has unique propertiesSign related to its up to vote on chemical this title structure biological activities. To understand the preventive and therapeutic useful Useful Not properties of MSM, a distinction needs to be made between "why hum need sulfur" vs. "why humans need MSM" .
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is made up of a unique collection of amino acids in a specific combina Two molecules cysteine can oxidize and bond together through sulfur ) bonds (5). These sulfur bonds are the key factors that hold proteins shape, and determine the form properties and biological activity of pr
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Nails and hair primary consist of a tough protein with a high sulfur con called keratin. Flexible tissues like connective tissue and cartilage, con proteins with flexible sulfur bonds. Collagen is the most abundant pro the body, and a major component of all connective tissue. In skin, col works with fibers of another protein called elastin, to give skin its elas In cartilage, the sulfur containing proteoglycans glucosamine and chondroitin form with collagen a fibrous protein substance that give cartilage its structure and flexibility (5, 6).
The importance of the connective tissue for the body goes beyond sim keeping cells together. The first biophysical regulatory model was developed by Prof. Dr. Pischinger which he termed the "Vegetative Bu Structure." This theory was further developed by Prof. Dr. Heine who described proteoglycans and glycosamines, and by Dr. Popp, a biophy who showed the importance of electromagnetic fields in bio-informati Their research has demonstrated that the soft, connective tissue, the extracellular matrix which surrounds cells, serves more purposes that structural and connective. It also is important in the transport of nutri electrolytes, signal compounds and atomic and subatomic particles. T the soft connective tissue forms an essential communication network You're Reading of a Preview the body through the transfer fine matter bio-information (13 -16). Unlock full access with a free trial.
As many people notice later in life, the flexible tissues lose their elast properties. A shortage of sulfur is the likely cause of this problem. The Download With Free Trialand joints, rippling of the skin consequences are stiffening of muscles decreased elasticity of lung tissues and arterial blood vessels. Withou doubt, the transfer of bio-information through soft connective tissue deceases also, and the occurrences of diseases at advanced age may be caused by a decrease in communication between cells and body tis Ce l l Me m b r a n e P e r m e a b i lit y
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Useful Not useful All cells (and all organelles within cells) are surrounded by membrane membrane consists of two layers of molecules situated opposite of
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Recent insight in free radical pathology has shown that the thiol (-SH) groups of sulfur containing amino acids can protect cell membrane pr chains from oxidation. But that is not all. Studies by Dr. Johanna Bud have demonstrated that sulfur containing amino acids in cell membra resonate with the double connections of the fatty acids, resulting in th release of electrons. Electron clouds are formed, which can move alon fatty acid chains. In this manner, electrical currents evolve which form basis of all electrical energy in the body. This energy can be measured heartbeat, nerve stimulations, muscle contractions, in short, in all che and electrical reactions which make life possible. Metabolism
Enzymes are proteins which control all-important life functions. For example, they regulated all metabolic processes in our bodies. Sulfur bridges are responsible for the spatial structure of enzymes. Without bridges, enzymes would lack biological activity due to deviations in th spatial structure. Shortages in sulfur cause reduced production of biologically active enzymes, which result in a reduction of many meta processes. Sulfur is important for the cellular energy production in glucose is metabolized under the release of energy.
Most important, sulfur plays a role in the electron transport system, a of iron/sulfur proteins in mitochondria, the energy factories of the cell Furthermore, sulfur participates in the vitamin-B Thiamine (B1) en Bio These vitamins are essential for converting carbohydrates into energy burning glucose. Insulin is a hormone excreted by the pancreas which Reading a blood Preview mainly functionsYou're to regulate the sugar level. Insulin therefore p an important role in the carbohydrate metabolism. Each insulin molec Unlock full access with a free trial. consists of two amino acid chains, connected to one another by sulfur bridges (Figure 4). These sulfur bridges are very important for the pro functioning of insulin. Without bridges, the hormone loses its Download Withthese Free Trial biological activity.
WHY DOES THE HUMAN BODY NEED MSM? P r e f e r r e d D ie t a r y S o u r c e o f S u lfuSign r up to vote on this title
Useful Not useful It is generally believed that in humans, the sulfur-containing amino ac methionine and cysteine are the most important sources of sulfur. Ho since the discovery of the earth's sulfur cycle, this theory is i ncreasing
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explained by the way food is processed in our western society, which causes the loss of the majority of the naturally present MSM. It is the for good reason that MSM is referred to as "The Forgotten Nutrient" (6 P r o t e c t io n o f t h e Mu c o s a
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Additional experiments with MSM containing radiolabeled sulfur demonstrated that after ingestion, MSM is bound to the mucosa. Apparently, MSM is binding to receptor sites at the mucous membran surface in the intestinal and urogenital tracts and the respiratory syst By doing so, it presents a blocking interface between host and environ (4). There are many health-benefitting implications to such natural interactions. Allergens and parasites cannot bind to the mucosa, toxin oxidized and free radicals are eliminated.
WHAT CAN MSM DO FOR YOU?
Deficiencies in biological sulfur can result in less optimal functioning o cell, tissue and organ in the body. Inorganic sulfur is poorly assimilate Organic, biologically active sulfur is therefore extremely important for health of every living organism. MSM is the natural source of biologica sulfur. Use of MSM has the following benefits: Ch r o n i c P a in
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Perhaps the most remarkable discovery regarding MSM is, that MSM effective pain killer which works with many types of chronic pain. In Unlock full access with a free trial. 1999 a remarkable book was published: “The Miracle of MSM: The Na Solution for Pain”. This book is based on the experience of two medica Download With MSM. Free Trial doctors who have worked with The authors are: Stanley W. Jac M.D., Head of the DMSO Pain Clinic in Portland, OR, and Professor at Oregon Health Sciences University; and Ronald M. Lawrence, M.D., Ph Founder of the International Association for the Study of Pain, and the American Association for the Study of Headaches. Both doctors discus extensive experience with MSM in this book. Combined, they have ov years of experience with fighting pain with MSM. They conclude th Sign up tochronic vote on this titleabout 70% h more than 18,000 patients that suffer from pain, Usefuli.e.,the Notpain useful experienced benefits from the use of either dimini MSM, or disappeared altogether.
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MSM is a natural analgetic: it blocks the transfer of pain impuls through nerve fibers (C-fibers). MSM blocks inflammations and inflammatory processes. MSM enhances the activity of cortisol, a natural anti-inflammatory hormone produced by the body. MSM improves the permeability of cell membranes. This impro the uptake of nutrients and many vitamins and the elimination waste products and excess cellular fluids. MSM dilates bloood vessels, enhancing the blood circulation. too, helps to eliminate waste products from the body, which sp up healing. MSM is a muscle relaxant. This is an important and often overlo benefit of MSM. Many chronic pains are aggrevated by chronic muscle tension in the body. MSM aids the natural defense mechanisms in the body by regu the prostaglandin metabolism, and regulates the formation of anitbodies and immune complexes.
MSM slows down and restores crosslinking in collagen. Crosslin in collagen is a natural process in scar formation, causing hard often painful scar tissues. Particularly in the case of burn scars, which large surface areas may be affected, this may lead to chr pain. MSM heals scar tissue which makes the skin more flexible Dramatic examples are known of people who have treated burn with a MSM ointment and have seen their scars almost disappe have eliminated associated pains.
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MSM is considered a potentiator of most vitamins and other nutrients, as vitamin C, Coenzyme Q10, all B- vitamins, vitamin A, D en E, amin acids, selenium, calcium, magnesium en many others. MSM improves cellular uptake of these nutrients, and prolongs their lives (5, 6, 8). T body can better utilize the nutrients, and taking dietary supplements more efficient. Additionally, fewer dietary supplements need to be tak Sign up to vote on this title Antioxidant
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MSM is a strong antioxidant, capable of binding and inactivating free
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body's anti oxidation system. When neutralizing free radicals, the bod a variety of antioxidant enzymes that contain sulfur amino acids, and their structure and biological activity from sulfur bonds (S-S). Besides provides the sulfur for the amino sulfur acids methionine, cysteine an taurine, that are considered powerful antioxidants. When split off, the SH) groups of these amino acids are capable of neutralizing free radic (17). Sulfur is also necessary for the formation of what is considered t most powerful nutritional antioxidant, glutathion (5). And as stated be MSM potentiates the effect of well known nutritional antioxidants as th vitamins C and E, coenzyme Q10, selenium etc. (5, 7). MSM itself also appears to act as an antioxidant (7). The mucosa contains a carbon-s bond cleaving enzyme, termed C-S lyase. Studies suggest that when to the mucosa, cleavage of MSM provides an electron deficient group CH3SO2 which can neutralize free radicals (4). Detoxification
MSM is known to dissolve in many organic and inorganic compounds ( Bound to the mucosa and split into an electron deficient group CH 3 MSM reacts with toxins, affects inactivation and speeds excretion (4). Furthermore, MSM enhances the permeability of cell membranes, mak easier for nutrients to be taken up by the cells, and waste products to eliminated. Practically speaking, MSM drastically increases the ability cells to excrete toxic waste products. Many health practitioners workin with MSM will state, that it is the most powerful detoxifying nutraceut pharmaceutical agent they have ever worked with.
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A recent example shows the dramatic detoxification action of MSM. A artist sought help in a psychiatric institution for severe mental compla Unlock full access with a free trial. Anti-depressives worsened his complaints to such degree that he deci look for alternative care. Microscopic examination of his blood using th Blood / HLB testDownload showed undeniably that the man suffered from sever With Free Trial heavy metal and solvent poisoning caused by the paints which he use his art work. This person subsequently sought the help of various trad and alternative medical professionals who prescribed various pharmaceutical drugs, homeopathic and orthomolecular detoxifier as bioresonance therapy. After one and one half years of detoxification t blood picture had somewhat improved, but he still exhibited severe to Sign up to vote on this title symptoms (Figure a). Useful Not useful
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microscopic examination showed that his blood had returned to norma (Figure b), and he indicated that, for the first time since seeking treat he had noticed a significant improvement in his condition. N e u r o l o g ic a l D is e a s e s
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The brain is extremely sensitive to the effects of toxic materials such heavy metals and organic compounds. Many of these compounds tend accumulate in nerve cells where they can cause severe oxidative dam Neurological disturbances such as Alzheimer's and Parkinson's disease be the result. MSM is one of the few antioxidants which can easily pas blood-brain barrier. It prevents and repairs oxidative damage and res cell membrane elasticity and permeability. This allows the nerve cells start excreting waste products.
The powerful action of MSM is illustrated in the following example. An woman suffered from poisoning caused by exposure to aluminum. Thi heavy metal had accumulated in her brains and caused severe neurol damage. The woman had been confined to her bed for six years, unab communicate with her surroundings. All this time she had not spoken word. Medical doctors could no longer help her and had given up on h She was completely dependent on her husband who took complete ca her needs. A natural health care practitioner advised two teaspoons o (about 15 grams) daily. The MSM passed the blood brain barrier, and restored the permeability of the brain cell membranes, following whic brain cells were allowed to purge the heavy metal poisons. Two weeks the orthomolecular physician prescribed a warm bath to her in which Reading Preview substances had You're been added to a help her eliminate the released poisons through the skin. After twenty minutes in this bath, the woman sudde with a free trial. now." These were the first w smiled and saidUnlock "Gee,full I access feel much better she had spoken in years. Several months later, the woman was capab leading a normalDownload life againWith (7). Free Trial Allergies
MSM alleviates the symptoms of a large number of allergies including allergies, contact allergies, inhalation allergies, etc. The major anti-all property of MSM is probably caused by to this bind to the mucos Signits upability to vote on title present a natural blocking interface between and allergens. Bes useful Useful hosts Not MSM alleviates allergies through detoxification and elimination of free radicals, and improvement of cell permeability. A direct correlation be concentration of MSM used and resistance to allergens has been
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Researchers have found that two-month old mice who were given wat containing a 3% solution of MSM for a period of three months suffered degeneration of articular cartilage. In the control group of mice receiv only tap water, 50% of the animals were found to have focal degener of articular cartilage. Nearly all (95%) control animals had inflammato reaction in the synovial tissues, compared to less severe inflammator reaction in 50% of the MSM group (8, 10). The beneficial effect of MS due in part to its ability to improve cell permeability, allowing harmfu substances (lactic acid, toxins) to flow out while permitting nutrients t in, thereby preventing a pressure buildup in cells that causes inflamm in the joints (5).
Mice prone to the development of Autoimmune Lymphoproliferative D (ALD) were fed a diet that included a 3% solution of MSM as drinking from the age of one month. The mean life span of the control group w months, whereas the mean life span of the MSM group was extended more than 10 months of age. The MSM group showed decreased antinuclear antibody responses and significant diminution of lymphadenop splenomegaly and anemia development, thus suggesting that MSM pr significant protection against the development of the autoimmune dis ALD (12). Other experiments were conducted on mice bred for their propensity to acquire the autoimmune disease Systemic Lupus Erythematosus (SLE).
These experiments showed MSM to have a protective effect both befo after the onset of the disease. Mice which are maintained on a diet inc 3% MSM in their drinking water from age one month, suffered lower d You're Reading a Preview rates and liver damage than control groups drinking only tap water. A seven months 30% of the control group had died, while all the MSM Unlock full access with a free trial. were still alive. Also, when mice seven months old and already showin signs of advanced lupus were fed the MSM diet, 62% of the animals w Download With Free Trial still alive after nine months compared to 14% for the control group th received only tap water (8). Cancer
Several experiments have shown, that oral administration of MSM can Sign up to vote on this title protect rats against the onset of cancer. In one study, rats specially b be susceptible to breast cancer when Usefulcertain useful given Notcarcinogenic compounds, were fed a diet containing MSM for a period of eight days control group did not receive MSM. Following this preliminary period,
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Parasites
One of the most amazing discoveries on MSM is its anti-parasitic actio against Giardia, Trichomonas, roundworms, nematodes, Enterobius an other intestinal worms (5). Animal studies include laboratory mice, determined to have pin worms (Enterobius) by fecal cast examination were given commercial food and drinking water, both containing 2% M by weight. After 17 days, fecal examination indicated the feces were f worms and eggs. The blood level of MSM in one animal examined exc 30 ppm or mg/kg (3). Human studies include a man with confirmed lam blia , apparently contacted from contaminated water in a primitive He was given 500 mg MSM three times a day for 14 days. By the eigh he was free of symptoms, and two stool specimens collected one wee were free of the organism (3). In another study, Trichom ona s vag inal successfully treated by oral dosage of 1 gram MSM a day, and a daily topical application of 5% aqueous MSM for one week (3).
The major antiparasitic property of MSM is probably caused by its abil bind to the mucosa and present a natural blocking interface between and parasites. It's as though MSM puts down a coating on the mucosa which parasites find impenetrable and can't cling to. Unable to stick, t parasites are simply flushed out of the body (5, 9). In vitro research h shown the antiparasitic, antifungal and antibacterial action of MSM concentrations. MSM concentrations of 1 mg/mL and less demonstrate significant inhibition of Giard ia lam blia . However, at 20 mg/mL concentrations it was strongly inhibitory, and concentrations above 40 mg/mL promptly killed the organism. According to Dr. Herschler, one You're a Preview safely administer up toReading 1-2 gram MSM per kg body weight on a daily One therefore builds a safely tolerated blood level up to 4000 ppm Unlock full access with a free trial. which level is highly toxic to many infective organisms yet is harmless the host (3).
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A growing number of natural physicians are expressing concerns abou parasites. It is becoming increasingly clear that they can be a continu source of poisoning which can spread throughout the body and affect immune system. It is an intriguing thought that MSM maybe nature's original means of protecting us against parasites. Sign up to vote on this title Diabetes
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The sulfur-containing B vitamin biotin is a critical part of glucokinase,
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cured by using MSM. An elderly woman was slated to have an operati performed on both wrists. On the advice of the author she started usi MSM. A month later her symptoms had all but disappeared, and the operation was no longer necessary.
Athletes who compete vigorously can learn from trainers of million-do racehorses. For many years and with great success, trainers administ MSM to their prize horses before a race to prevent muscle soreness, a afterwards to lessen the risk of cramping and improve physical recove (4). The physical fatigue syndrome following intense athletic activity i competitive sports, which usually persist for 8-10 days in athletes, wa gone in 2-3 days in individuals who had ingested 1-2 gram MSM per d the preceding six months (3) Co n s t ip a t io n a n d S t o m a c h Ac id it y
One study reveals, that at least 75% of individuals taking one or more antacids or H 2 histamine receptor antagonists against stomach acidity able to sharply reduce or eliminate such medication within a week of initiating MSM as a dietary supplement. In another study, twenty-one subjects with a history of constipation were given 500 mg daily doses MSM together with 1 gram of ascorbic acid. All subjects with abnorma function returned to normal and remained normal while MSM was par their diet (5). These studies point out, that MSM often gives more reli from stomach acidity and constipation, than commonly prescribed medication. Many people have experienced, that one of the most exci and rewarding benefits for those who begin taking MSM, has been the You're Reading a Preview prompt and continuing relief from stomach acidity and constipation problems (7). Unlock full access with a free trial.
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MSM allows the body to more effectively take up oxygen. In the first p it improves the elasticity of the lung cells and the permeability of long membranes, allowing more air to be breathed and oxygen to pass thr the membranes into the blood stream. Secondly, MSM prevents and corrects the clotting of red blood cells, allowing the blood to absorb m to vote on this title oxygen. Moreover, by improving the Sign cell up membrane permeability, cell throughout the body can take up more oxygen from blood, and he Not the useful Useful produce more energy. People suffering from lung dysfunctions may be greatly from treatment with MSM. In one study, seven human subject respiratory deficiency were given MSM in amounts ranging from 250
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from seven months to over one year, none of them became ill (3). On stress study involved two groups of 25 goldfish, which were removed a large aquarium and placed in two identical, small aquariums. One g was fed ordinary goldfish food, and the other group received the same with 2% by weight of MSM added. Movement confinement, temperatu changes and marginal oxygenation stressed the fish in both aquarium equally. After five days, only one fish of the MSM group had died, aga 11 (almost 50%) of the control group (3).
It is common practice in intensive cattle breeding to add antibiotics to animal feed to promote growth and prevent the outbreak of stress-re diseases. Animal products such as meat, milk and eggs contain residu antibiotics, which are readily consumed. The abundant usage of antibi is largely responsible for the creation of resistent bacteria strains. We known examples are the "hospital bacterium" MRSA (meticillin resista S t a p h y lo c o cc u s a u r e u s ), and the VRE's (vancomycin-resistant enteroc Today, increasing resistance of bacteria is considered one of the majo threats of human health. It is an intriguing thought that adding MSM animal feed might reduce stress and improve animal health to a level the usage of antibiotics can be strongly reduced. Skin
Sulfur is called nature's "beauty mineral," because it keeps the skin sm and youthful, and the hair glossy. Sulfur is necessary for production o collagen and keratin, protein necessary for health and maintenance of nails and hair (6). Several experiments have shown, that all kinds of You're Reading Preview dermatological disorders whichaare often allergy-related, respond favo to a diet supplemented by MSM. Oral dosages of MSM have shown to Unlock fullRosaceae access with aand free trial. effective against acne, dry, scaly or itching skin(3). Wh used topically in the form of an ointment or lotion, MSM is helpful in treating skin disorders including acne, psoriasis, eczema, dermatitis, Download With Free Trial dandruff, scabies, diaper rash and certain fungal infections (1, 6). Sca resulting from operations and from burns also respond well to topical application. New scars can heal so perfectly, that they are almost invi Old scars, too, can improve markedly. F O R W H O M I S M S M I N T EN D E D ?
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Not useful Useful MSM is intended for everyone who appreciates good health and intend keep this as long as possible. Sport enthusiasts and athletes can use improve their performance and sped up recovery. People with degene
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The optimal dosage depends on the nature and intensity of the compl In most cases, it is sufficient to take an initial dose of three 1-gram ta twice daily (children ten and under take a tablet twice daily, older tha take two tablets twice daily). After several months this dosage can be reduced to two tablets twice daily. People with serious ailments have shown to benefit from higher dosages, up to four 1-gram tablets three times daily. Such a high dosage may be advised to fight parasital infe Case studies have been reported in which patients did not show notice improvement until they received a daily dosage of 30 grams (6). Such extreme dosage is not generally recommended for most people, altho no negative effects were reported (3,6).
It is recommended to gradually increase the dosage from two tablets daily, and not to increase the dose as long as detoxification symptom persist. Although uncommon, these symptoms may include nausea an headaches (see below). MSM is best taken with a glass of water one h hour prior to taking a meal. As it tends to stimulate one's energy leve generally advisable not to take it prior to retiring for the night.
You're Reading a Preview HOW S A FE I S M S M? Unlock full access with a free trial.
MSM is considered to be one of the least toxic substances in biology, in toxicity to water. When MSM was administered to human volunteer Download With Free Trial toxic effects were observed at intake levels of 1 gram per kg of body per day for 30 days. Intravenous injections of 0.5 grams per kg body weight daily for five days a week produced no measurable toxicity in h subjects. The lethal dose (LD50) of MSM for mice is more than 20 g/k body weight. MSM has been widely tested as a food ingredient withou reports of allergic reactions. An unpublished Oregon Health Sciences of six University study of the long-term toxicity of MSM over a period Sign up to vote on this title months, showed no toxic effects. More than 12,000 patients were trea Usefulwithout useful (8). Nottoxicity with MSM at levels above two gramsdaily,
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Herschler, R.J.: Methylsulfonylmethane and Methods of Use. Un States Patent 4,296,130: 1981. Herschler, R.J.: Methylsulfonylmethane in Dietary Products. Un States Patent 4,616,039: 1986. Herschler, R.J.: Dietary Products and Uses Comprising Methylsulfonylmethane. United States Patent 4,863,748: 1989. Herschler, R.J.: MSM: a Nutrient for the Horse. Eq. Vet. Data, 1 Mindell, E.L.: The MSM Miracle. Enhance Your Health with Orga Sulfur. Good Health Guides, Keats Publishing, Inc, Connecticut, 1997. Ley, B.M.: The Forgotten Nutrient MSM: on Our Way Back to H with Sulfur. Health Learning Handbooks, BL Publications, Califo 1998. Owen, B.: Ask Dr. Bob?? Why MSM?? Health Hope Publishing H California, 1997 Jacob, S.W: The Current Status of MSM in Medicine. Am. Acad. Prev., 1983. Jacob, S.W. and Herschler, R.J.: Introductory Remarks: Dimethylsulfoxide after Twenty Years. Ann. N.Y. Acad. Sci.: 198 Moore, R.D. and Morton, J.I.: Diminished Inflamatory Joint Dis Mice Ingesting Dimethylsulfoxide (DMSO) or Methylsulfonylmet (MSM). Fed. of Am. Soc. for Exp. Biol., Proceedings 69th Ann. Meeting 1985: 692. Richmond, V.L.: Incorporation of Methylsulfonylmethane into G Pig Serum Proteins. Life Sciences 1986, vol. 39, pp 263-268. Morton, J.I. and Siegel, B.V.: Effects of Oral Dimethylsufoxide You're Reading a Preview (DMSO) and Dimethylsulfone (MSM) on Murine Autoimmune Lymphoproliferative Disease. Proc. Of the Soc. for Exper. Bio. a Unlock full183, accesspp. with227-230. a free trial. Med. 1986, vol. Munck-Khoe, L.K. de: Vitaminen, Hardware of Software? Deel 1 Ortho 14(5), 1996: With 204-211. Download Free Trial Munck-Khoe, L.K. de: Vitaminen, Hardware of Software? Deel 2 Ortho 14(6), 1996: 252-261. Vos, R. de: De Magie Van Het Leven Zit in De Chemie. Folia Or 1998 (1): 7-10. Lamers, H.J.: Ferdinand Huneke, Ontdekker en Grondlegger va Neuraaltherapie. Tijdschr. Voor Integr. Geneesk. 1996;12(1): Sign up to vote on this title 22. Nieuwenhuis, R.A.: Anti-oxidanten, De Effectieve Beschermers Useful Not useful Onze Gezondheid. Orthos Media, Den Haag, 1993
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