MR-96A

MR-96A Microplate Reader

Service Manual

© 2007 Shenzhen Mindray Bio-medical Electronics Co., Ltd. All rights Reserved. For this Manual, the issued Date is 2007-05 (Version: 1.0).

Intellectual Property Statement SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (hereinafter called Mindray) owns the intellectual property rights to this Mindray product and this manual. This manual may refer to information protected by copyrights or patents and does not convey any license under the patent rights of Mindray, nor the rights of others. Mindray does not assume any liability arising out of any infringements of patents or other rights of third parties. Mindray intends to maintain the contents of this manual as confidential information. Disclosure of the information in this manual in any manner whatsoever without the written permission of Mindray is strictly forbidden. Release, amendment, reproduction, distribution, rent, adaption and translation of this manual in any manner whatsoever without the written permission of Mindray is strictly forbidden. , , , trademarks or trademarks owned by Mindray in other trademarks that appear in this manual are without the intention of improperly using them. respective owners.

, are the registered China and other countries. All used only for editorial purposes They are the property of their

Responsibility on the Manufacturer Party Contents of this manual are subject to changes without prior notice. All information contained in this manual is believed to be correct. Mindray shall not be liable for errors contained herein nor for incidental or consequential damages in connection with the furnishing, performance, or use of this manual. Mindray is responsible for safety, reliability and performance of this product only in the condition that:

all installation operations, expansions, changes, modifications and repairs of this product are conducted by Mindray authorized personnel; the electrical installation of the relevant room complies with the applicable national and local requirements; the product is used in accordance with the instructions for use.

WARNING: It is important for the hospital or organization that employs this equipment to carry out a reasonable service/maintenance plan. Neglect of this may result in machine breakdown or injury of human health.

i

NOTE: This equipment is to be operated only by clinical professionals, doctors or laboratory experimenters trained by Mindray or Mindray-authorized distributors.

Warranty THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE.

Exemptions Mindray's obligation or liability under this warranty does not include any transportation or other charges or liability for direct, indirect or consequential damages or delay resulting from the improper use or application of the product or the use of parts or accessories not approved by Mindray or repairs by people other than Mindray authorized personnel. This warranty shall not extend to:

any Mindray product which has been subjected to misuse, negligence or accident; any Mindray product from which Mindray's original serial number tag or product identification markings have been altered or removed; any product of any other manufacturer.

Return Policy Return Procedure In the event that it becomes necessary to return this product or part of this product to Mindray, the following procedure should be followed: 1

Obtain return authorization: Contact the Mindray Service Department and obtain a Customer Service Authorization (Mindray) number. The Mindray number must appear on the outside of the shipping container. Returned shipments will not be accepted if the Mindray number is not clearly visible. Please provide the model number, serial number, and a brief description of the reason for return.

2

Freight policy: The customer is responsible for freight charges when this product is shipped to Mindray for service (this includes customs charges).

3

Return address: Please send the part(s) or equipment to the address offered by Customer Service department

Company Contact

ii

Manufacturer:

Shenzhen Mindray Bio-Medical Electronics Co., Ltd.

Address:

Mindray Building, Keji 12th Road South, Hi-tech Industrial Park, Nanshan, Shenzhen 518057, P.R.China

Tel:

+86 755 26582479 26582888

Fax:

+86 755 26582934 26582500

Preface Who Should Read This Manual The manual is written for service professionals authorized by Mindray.

Conventions Used in This Manual Safety Symbols This chart explains the symbols that may be used in this manual. When you see …

WARNING:

BIOHAZARD:

CAUTION:

NOTE:

Then …

Read the statement following the symbol. The statement is alerting you to an operating hazard that can cause personal injury. Read the statement following the symbol. The statement is alerting you to a potentially biohazardous condition. Read the statement following the symbol. The statement is alerting you to a possibility of system damage or unreliable results. Read the statement following the symbol. The statement is alerting you to information that requires your attention.

Preface

1

Contents Preface............................................................................................................... 1 Who Should Read This Manual.......................................................................................... 1 Conventions Used in This Manual...................................................................................... 1

1

System Features ...................................................................................1-1 1.1

Specifications........................................................................................................ 1-3

1.2

Moving Parts......................................................................................................... 1-3

1.3

User Interface ....................................................................................................... 1-4

2

System Installation ...............................................................................2-1

3

Components and Parts.........................................................................3-1

4

3.1

Lamp Housing Assembly ...................................................................................... 3-3

3.2

Optical Fiber Box Assembly.................................................................................. 3-3

3.3

Filter Wheel Assembly .......................................................................................... 3-5

3.4

Filter Wheel Motor Assembly................................................................................ 3-6

3.5

Microplate Holder Module..................................................................................... 3-6

3.6

Bottom Cover Assembly ....................................................................................... 3-8

3.7

Top Cover Assembly............................................................................................. 3-9

Hardware Boards ..................................................................................4-1 4.1

CPU Board............................................................................................................ 4-3 4.1.1 4.1.2

4.2

CPU Extension Board........................................................................................... 4-4 4.2.1 4.2.2 4.2.3 4.2.4

4.3

USB ......................................................................................................... 4-4 LCD Drive and Control............................................................................. 4-5 Touchscreen Control................................................................................ 4-5 Serial Port Communication...................................................................... 4-5

Driver Board.......................................................................................................... 4-6 4.3.1 4.3.2 4.3.3 4.3.4 4.3.5

4.4

Storage .................................................................................................... 4-4 Clock........................................................................................................ 4-4

Serial Port Communication...................................................................... 4-6 Step Motor Drive ...................................................................................... 4-7 Position Signal Detection......................................................................... 4-7 Lamp Control ........................................................................................... 4-7 Analog Board Control .............................................................................. 4-8

Analog Board ........................................................................................................ 4-8 4.4.1 4.4.2 4.4.3

Photoelectricity Conversion & Amplification ............................................ 4-8 Conditioning............................................................................................. 4-9 AD Collection ........................................................................................... 4-9

Contents

I

4.5

Touchscreen Conversion Board .........................................................................4-10 4.5.1 4.5.2 4.5.3 4.5.4

5

4.6

Power Supply Board ........................................................................................... 4-11

4.7

Connecting Diagrams ......................................................................................... 4-11

Maintenance and Service .................................................................... 5-1 5.1

Maintenance .........................................................................................................5-3 5.1.1 5.1.2

5.2

5.3

Replacing Lamp.......................................................................................5-4 Replacing Filter ........................................................................................5-4 Replacing Optical Fiber ...........................................................................5-5

Adjustment............................................................................................................5-5 5.3.1 5.3.2

5.4

Daily Maintenance ...................................................................................5-3 Half-yearly Maintenance ..........................................................................5-3

Service ..................................................................................................................5-3 5.2.1 5.2.2 5.2.3

Adjusting Filter Wheel Motor Assembly ...................................................5-5 Adjusting Belt Tension of Microplate Holder Module ...............................5-6

Software Upgrade.................................................................................................5-6 5.4.1 5.4.2

II

Analog Input Protection .........................................................................4-10 Touchscreen Driver................................................................................4-10 Input/Output Buffer ................................................................................4-10 Power Supply.........................................................................................4-10

Software Upgrade for Driver Board .........................................................5-6 Software Upgrade for CPU Board ...........................................................5-7

Contents

1

System Features

1.1

Specifications........................................................................................................ 1-3

1.2

Moving Parts......................................................................................................... 1-3

1.3

User Interface ....................................................................................................... 1-4

System Features

1-1

1-2

System Features

1 System Features

1.1 Specifications

Dimension: 437mm×332mm×174mm (L×W×H) Weight: about 8.5Kg Power supply: 100-240V~, 50/60Hz Power: 120VA max

Photometric system: optical fibers; interference filters Light source: 20 VA tungsten-halogen lamp Half band-width: 10±2nm Wavelength: 405nm, 450nm, 492nm, 630nm. Another 4 wavelengths can be added according to user’s requirements. Absorbance: 0-3.5 Abs Microplate: 96-/48-well plates

Calculation mode: Absorbance, Qualitative, Quantitative Calibration method: One-point, Point-to-Point, Multi-point, Linear, Exponential, Logarithm, Power, Factor QC rule: 1 control value exceeds ±3SD, 2 consecutive values exceed ±2SD, 5 consecutive values lie on one side of ±2SD, 7 consecutive values lie on one side of the axis

Microplate shaking speed: high, medium, low Microplate shaking time: 0~60s Sample mode: single sample, dual samples Test: 12 tests can be set in a microplate Microplate reading speed: In the Step mode, 12s/plate for single wavelength and 26s/plate for double wavelength; In the Continuous mode, 5s/plate for single wavelength and 12s/plate for double wavelength.

Result saving: 20,000 results can be saved Tests saving: 100 tests can be saved

1.2 Moving Parts The moving parts in the apparatus are the microplate support and the filter wheel.

The microplate support holds the microplate and moves it to the measuring position.

System Features

1-3

The trace of the support is home position → measurement home position → measurement end position → measurement home position → home position. The trace is as long as four plates. The support can move in two mode, Step and Continuous.

The filter wheel rotates the filter of corresponding wavelength to the optical path according to the setting.

1.3 User Interface The apparatus provides friendly user interface.

1-4

System Features

2

System Installation

System Installation

2-1

2-2

System Installation

2 System Installation 1

Ensure the installation field in the hospital is available. Refer to the Operation Manual for installation space, power supply, environmental requirements, etc.

2

Go to the installation site. Check the delivery list and unpack the package.

3

Move the system in place.

4

Open the enclosure to check if cable and screws are loose or disconnected.

5

Connect the system to the power socket with the power cable.

6

Turn on the system.

7

The system begins self-check and prompt information appears on the screen. Check if any warning message appears on the screen and hear if there is abnormal sound from moving parts.

8

Train users. Can the user complete routine tests?

Yes □ No □

Does the user know how to maintain the system?

Yes □ No □

Does the user know how to clean the system?

Yes □ No □

Does the user know how to replace the lamp?

Yes □ No □

System Installation

2-3

3

Components and Parts

3.1

Lamp Housing Assembly ...................................................................................... 3-3

3.2

Optical Fiber Box Assembly.................................................................................. 3-3

3.3

Filter Wheel Assembly .......................................................................................... 3-5

3.4

Filter Wheel Motor Assembly................................................................................ 3-6

3.5

Microplate Holder Module..................................................................................... 3-6

3.6

Bottom Cover Assembly ....................................................................................... 3-8

3.7

Top Cover Assembly............................................................................................. 3-9


3-1

3-2


3 Components and Parts

3.1 Lamp Housing Assembly The lamp housing assembly is shown as the figure below. The lamp is located and fixed by an extension spring, which is not shown in the figure below. Lamp Base

Lamp

Lamp Housing

Magnet

Spring Pins

Plug Screw

Convex Lens

Do not remove the spring pins, which are pressed into the lamp housing, and the magnet, which is stuck in the lamp housing, from the housing unless they are damaged. Before removing the convex lens, unscrew the plug screw first. After placing the lens back or replacing it with a new one, be sure to tighten the plug screw. When removing the lamp from the housing or placing it into the housing, be sure to pinch the lamp tightly to avoid the lamp damage caused by spring force. When disassembling the lamp, take out the lamp along with the lamp base from the housing and then remove the lamp from the base; When assembling the lamp, install the lamp on the base and then place it into the housing. The assembly is located on the bottom cover of the system by two spring pins. Its position should not be adjusted.

3.2 Optical Fiber Box Assembly Optical fibers in the box are shown as the figure below.


3-3

The following figure shows the optical fiber box assembly. Bracket

Retainer Rings

Lenses

Optical Fiber Box

Cover

Diaphragms

Optical Coupler

Filter Wheel Shaft Light Shield Spring Pins Optical Fiber To replace the optical coupler, disassemble the bracket first. Be sure to disassemble optical fibers before replacing the lenses. When disassembling lenses, you can use a cylinder to push out the diaphragm, lens and retainer ring together from the inside. When assembling them, you can use a flat object such as the handle of a screwdriver to push the retainer rings into the box. The diaphragm can touch the flat surface of lens with either side. Do not disassemble the retainer rings often to avoid their performance degradation. Be sure to check if the retainer rings match the lenses well after each installation. If not, replace them with new ones. Dust accumulated on the lenses may degrade system performance. You can use a gas bag or a soft brush to remove dust. Before cleaning, disassemble the microplate holder assembly to expose the lens. Before disassembling the optical fiber assembly, dissemble the optical fiber box assembly first. When fixing the fibers, place their ends close to the inside surface of

3-4


box and do not use excessive force to tighten the retaining screws. Add some specific cohesive material on the screws to secure them. There is no need to maintain the filter wheel shaft unless it cannot be pushed or pulled in the axial direction with its retaining screw removed. The optical fiber box assembly is located on the bottom cover of the system by two spring pins. Its position should not be adjusted.

3.3 Filter Wheel Assembly The filter wheel assembly is shown as the figure below. Diaphragms

Filters

Pressure Springs Press Plate

Filter Wheel

Iron

Blocks

Screws

Do not remove the iron, which is pressed into the filter wheel, from the wheel unless it is damaged. To take out the iron from the wheel, use a column such as the handle of a screwdriver to push it out from the bigger side of the wheel. Replace filters when their performance degrade. Before replacing them, release the screws and remove the press plate and then pressure springs. Be sure to place filters into their corresponding holes in the wheel according to the wavelengths labeled on them and make their wider sides face the wheel bottom. Exercise caution to prevent filters from being stained or damaged. Then place blocks into the other holes with their sides having apertures facing the wheel bottom. Finally, place pressure springs and the press plate back, aim the three holes in the press plate at any three ones in the wheel, and then tighten the screws. The three diaphragms are different with the largest one for 450nm, the smallest one for 630nm, and the last one for 492nm. You can place a diaphragm with its either side facing a filter. Dust accumulated on the filter wheel may degrade its performance. Use a gas bag or a soft brush to clean it. Be sure to install the lamp housing assembly and the optical fiber box assembly before installing the filter wheel assembly. The location of filter wheel assembly is fixed automatically by the filter wheel shaft on the optical fiber box assembly and the magnet in the lamp housing assembly.


3-5

After installing the filter wheel assembly, be sure to check if it rotates smoothly. If not, find out the problem and resolve it.

3.4 Filter Wheel Motor Assembly The filter wheel motor assembly is shown as the figure below.

Spring Pin Gear

Motor Bracket

Screws

The gear is plastic. Replace the gear when it is damaged. Use diagonal cutting pliers to cut the hub and replace the gear with a new one. The spring pin cannot be used any more and be sure to replace it with a new one. Install the filter wheel motor assembly after the lamp housing assembly, the optical fiber box assembly and the filter wheel assembly are installed. Adjust the location of the filter wheel motor assembly when installing it to make the gear and the filter wheel mesh well.

3.5 Microplate Holder Module The microplate holder module is shown as the figure below.

3-6


Cover

Cell Backing

Analog Board

Retainer Ring

Roller Wheel

Microplate Holder Assembly

Shelf

Roller Shaft

Spring Pin Guide Bar Receiver

Belt Wheel

Guide Bar Optical Coupler

Motor

Bottom Plate

When maintaining the module, check if screws are tighten, if the microplate holder assembly moves smoothly, and if the tension of the belt is appropriate. If not, find out the problem and resolve it. Wipe the two guide bars and the surface of roller shaft and lubricate them with grease lubricant every half year. You can use a gas bag or a soft brush to remove dust on the shelf and the analog board. Be sure to disassemble the analog board before cleaning. The tension is appropriate when the site is depressed 4±0.4mm as pressure of 0.2N is added on the belt. Do not add excessive tension on the belt. The microplate holder assembly is shown as the figure below.


3-7

Tension Block

Press Block

Press Plate

Spring Sheet

Nut Grid Bar

Microplate Holder

The grid bar and the nut are stuck to the assembly with epibond. When maintaining the assembly, check the grid bar and the spring sheet. If the grid bar is loose or disconnected, stick it. If the spring sheet cannot work, disassemble and adjust it, or replace it with a new one.

3.6 Bottom Cover Assembly The bottom cover assembly is shown as the figure below.

3-8


Water Retaining Plate

CPU Extension Board

Driver Board CPU Board Power Supply Enclosure

Pillar

Power Supply Board

Hinge Bases Power Switch

Power Jack

Support Leg

Bottom Cover

Replace the power switch, the power jack, or the boards with new ones when they are damaged. Be sure to connect them correctly after the replacement. Keep the grounding terminal on the bottom cover clean and rustfree and connect the earth wire to the grounding terminal.

3.7 Top Cover Assembly The top cover assembly is shown as the figure below.


3-9

Recorder Cover

LCD Dust Filter

Recorder Base Fan

Recorder

Top Cover

Touchscreen Touchscreen Backing LCD LCD Base Inverter Insulator Inverter Touchscreen Conversion Board

Press Plate Hinge

Indicator Movable Cover

LCD Conversion Board Connection Base

The LCD dust filter and the indicator are stuck to the top cover. The touchscreen and the LCD are stuck together with the touchscreen backing between them. The touchscreen backing is stuck to the touchscreen. The touchscreen and the LCD can be separated from each other. There is no need to maintain the top cover assembly unless the recorder, the screens or the indicator cannot work. Be sure to connect cables correctly after maintaining the assembly.

3-10


4 4.1

CPU Board............................................................................................................ 4-3 4.1.1 4.1.2

4.2

Serial Port Communication...................................................................... 4-6 Step Motor Drive ...................................................................................... 4-7 Position Signal Detection......................................................................... 4-7 Lamp Control ........................................................................................... 4-7 Analog Board Control .............................................................................. 4-8

Analog Board ........................................................................................................ 4-8 4.4.1 4.4.2 4.4.3

4.5

USB ......................................................................................................... 4-4 LCD Drive and Control............................................................................. 4-5 Touchscreen Control................................................................................ 4-5 Serial Port Communication...................................................................... 4-5

Driver Board.......................................................................................................... 4-6 4.3.1 4.3.2 4.3.3 4.3.4 4.3.5

4.4

Storage .................................................................................................... 4-4 Clock........................................................................................................ 4-4

CPU Extension Board........................................................................................... 4-4 4.2.1 4.2.2 4.2.3 4.2.4

4.3

Hardware Boards

Photoelectricity Conversion & Amplification ............................................ 4-8 Conditioning............................................................................................. 4-9 AD Collection ........................................................................................... 4-9

Touchscreen Conversion Board ......................................................................... 4-10 4.5.1 4.5.2 4.5.3 4.5.4

Analog Input Protection ......................................................................... 4-10 Touchscreen Driver................................................................................ 4-10 Input/Output Buffer ................................................................................ 4-10 Power Supply......................................................................................... 4-10

4.6

Power Supply Board........................................................................................... 4-11

4.7

Connecting Diagrams ......................................................................................... 4-11

Hardware Boards

4-1

4-2

Hardware Boards

4 Hardware Boards The hardware system consists of the following units and boards:

Main control unit: CPU board, CPU extension board Driver unit: Driver board Data collection unit: Analog board MMI unit: LCD conversion board, Touchscreen conversion board Power supply unit: Power supply board

4.1 CPU Board The CPU board, which constructs a minimal CPU system using a 32-bit SCM, and the CPU extension board constitute the main control unit. The CPU board communicates with the CPU extension board using the multiple bus mode and through CPU external interfaces.

Hardware Boards

4-3

4.1.1 Storage Flash, which uses Flex Bus to communicate with CPU, stores program of CPU. DDR SDRAM, which is controlled by the SDRAM controller integrated in CPU, is configured on the CPU board. Additionally, to store important parameters, EEPROM is configured on the CPU board.

4.1.2 Clock The CPU board has real-time clock circuit, which includes real-time clock, battery, etc., to achieve the real-time clock function.

4.2 CPU Extension Board The CPU extension board realizes the following functions for CPU external interfaces:

USB LCD drive & control Touchscreen control Recorder serial port communication Buzzer control PC serial port communication

CPU Extension Board UART3

Recorder

UART2

Driver Board

UART0

PC

SPI

LCD Contrast/Brightness Adjustment

CPU Board

VARM

VRAM

UART1 FPGA

Flex Bus

Touchscreen Conversion Board

SPI Display Driver Buzzer Controller

USB Controller

LCD Display Buzzer

USB Port

4.2.1 USB The USB controller on the CPU extension board communicates with CPU through PCI bus and communicates with USB ports to perform the USB function.

4-4

Hardware Boards

There are USB power supply controller and ESD between the USB controller and USB ports.

4.2.2 LCD Drive and Control The CPU extension board uses FPGA to drive and control the LCD. The FPGA receives data from CPU through FlexBus, stores the display data of CPU into VRAM, and outputs the data in VRAM to LCD according to the display schedule of LCD, whose control signals are driven by a buffer. CPU adjusts the digital potentiometers on the CPU extension board through SPI bus to adjust the contrast and brightness of LCD.

4.2.3 Touchscreen Control The CPU extension board uses FPGA to control the touchscreen. The FGPA achieves the following functions:

Extending a serial port to communicate with CPU Extending SPI port to control the touchscreen conversion board Realizing the data communication protocol with the software

4.2.4 Serial Port Communication The UART0 and UART2 ports of the CPU board communicate with PC and the driver board through the LVTTL↔RS232 level translator. The UART3 port communicates with the recorder through the LVTTL↔TTL level translator.

Hardware Boards

4-5

4.3 Driver Board The driver board consists of circuits of movement control and data collection. The driver board receives instructions from main control unit to control and drive moving parts, detect position signals, collect photoelectrical data, and transmit data to the main control unit.

4.3.1 Serial Port Communication The CPU of the driver board communicates with the main control unit through the LVTTL↔RS232 level translator.

4-6

Hardware Boards

4.3.2 Step Motor Drive

The CPU outputs two groups of signals, one (including the step pulse signal “step1” and the direction signal “dir1”) for the movement step motor and the other (including the step pulse signal “step2” and the direction signal “dir2”) for the rotation step motor. The signals are converted by LVTTL→TTL translators and then transmitted to the step motor drivers to control the step motors.

4.3.3 Position Signal Detection

The movement position signal and the rotation position signal are transmitted through the U17 shaping circuit and the CPLD to the CPU.

4.3.4 Lamp Control

The lamp needs +6V when working and +2V on standby. The voltage is provided by the DC/DC unit, which is controlled by the VSW signal from the CPU and sends VLAMP signal to the lamp. The VLAMP signal also feeds to the overvoltage/overcurrent protection unit, which controls the DC/DC unit to stop power supply to the lamp when overvoltage or overcurrent occurs. The MOS 1 and MOS 2, which are controlled by LAMPON and RSHT signals respectively, protect the lamp from being damaged by spike pulse during the switch.

Hardware Boards

4-7

4.3.5 Analog Board Control

There are three groups of signals to control the analog board: digital potentiometer control signal DCPx, channel gating signal CHx, and AD collection control signals AD_Ox and AD_Ix. All signals are generated from CPLD and processed by level translators.

4.4 Analog Board

The analog board consists of the following:

Photoelectricity conversion and amplification circuit, which converts current and voltage and reverses and amplifies signals Conditioning circuit, which have functions of multiple channel gating, gain adjustment and voltage following AD collection circuit

4.4.1 Photoelectricity Conversion & Amplification The circuit converts current and voltage of 8 paths of signals from photoelectric cells and reverses and amplifies them.

4-8

The current and voltage conversion circuit converts the signals from the photoelectric cells to voltage output. The reversion and amplification circuit reverses and amplifies the output from the conversion circuit, which is negative voltage, before outputting it to the conditioning circuit.

Hardware Boards

Analog Potentiometer Adjustment In the photoelectricity conversion and amplification circuit, the analog potentiometers should be adjusted to keep voltage the same. The potentiometers and their corresponding channels are shown as the following: Channel 1: VR1

Channel 2: VR2

Channel 3: VR3

Channel 4: VR4

Channel 5: VR5

Channel 6: VR6

Channel 7: VR7

Channel 8: VR8

4.4.2 Conditioning The 8 paths of signals from the photoelectricity conversion and amplification circuit travel through the multiple channel gating circuit, gain adjustment circuit and voltage following circuit to reach the AD collection circuit.

The multiple channel gating circuit selects specific channels to condition signals. The gating is realized by the multiplexer. The gain adjustment circuit makes the output signals approach to the maximum input amplitude voltage of the AD collection circuit. The gain is adjusted through the resistance of digital potentiometer (U12). Signals from the gain adjustment circuit are input into the voltage following circuit.

4.4.3 AD Collection The AD collection circuit converts analog signals from the conditioning circuit to digital signals.

A 16-bit resolution converter performs AD conversion. The reference source provides 5V reference voltage for the AD converter.

Hardware Boards

4-9

Signals between the analog board and the driver board are processed by the input/output buffer.

4.5 Touchscreen Conversion Board The touchscreen conversion board:

Tests if the touchscreen is clicked； Converts and transfers clicking position signals from the touchscreen.

4.5.1 Analog Input Protection A diode is used to prevent signals from the touchscreen from exceeding the input range of touchscreen driver. The diode also provides high-speed discharge circuit to eliminate static charges.

4.5.2 Touchscreen Driver

The touchscreen driver receives coordinate signals from the touchscreen and communicates with the input/output buffer through the input control signal CONTROLn and the output status signal STATEn.

4.5.3 Input/Output Buffer The input/output buffer converts 5V signals from the CPU extension board to 3.3V signals that can be used by the touchscreen driver, and also converts 3.3V signals from the touchscreen driver to 5V signals.

4.5.4 Power Supply The touchscreen conversion board is powered by the CPU extension board, which provides 5V signals.

4-10

Hardware Boards

4.6 Power Supply Board The power supply board outputs:

+5V: 2.0A, which is supplied to the boards; +12V: 3.0A, which is supplied to the lamp, analog board and recorder; +24V: 0.3A, which is supplied to step motors; -12V: 0.1A, which is supplied to the analog board.

The power supply board consists of:

EMI filter circuit; Rectification and filter circuit; Flyback converter, which outputs +12V, +24V and -12V; Voltage reducing circuit, which generates +5V from the +24V input; Overcurrent and overvoltage protection circuits for outputs;

4.7 Connecting Diagrams

Hardware Boards

4-11

4-12

Hardware Boards

Hardware Boards

4-13

CPU Extension Board 0104-30-62523 J8

1

2

3

4

5

6

7

7 7

8 8

8

Cable 0104-20-62484

J2

1 2 1 2

3 3

J2 4 5 4 5

6 6

Touchscreen Conversion Board 0104-30-62489 J1

1

2

3

4

Touchscreen 0000-10-11105

4-14

Hardware Boards

Hardware Boards

4-15

5 5.1

Maintenance ......................................................................................................... 5-3 5.1.1 5.1.2

5.2

Replacing Lamp....................................................................................... 5-4 Replacing Filter........................................................................................ 5-4 Replacing Optical Fiber ........................................................................... 5-5

Adjustment............................................................................................................ 5-5 5.3.1 5.3.2

5.4

Daily Maintenance ................................................................................... 5-3 Half-yearly Maintenance .......................................................................... 5-3

Service.................................................................................................................. 5-3 5.2.1 5.2.2 5.2.3

5.3

Maintenance and Service

Adjusting Filter Wheel Motor Assembly ................................................... 5-5 Adjusting Belt Tension of Microplate Holder Module ............................... 5-6

Software Upgrade................................................................................................. 5-6 5.4.1 5.4.2

Software Upgrade for Driver Board ......................................................... 5-6 Software Upgrade for CPU Board ........................................................... 5-7


5-1

5-2


5 Maintenance and Service

5.1 Maintenance 5.1.1 Daily Maintenance The following maintenance can be performed by users.

Check if the indicator can light up normally. Check if the screen can work and display properly. Check if the recorder can work properly. Check if there is abnormal sound when the system is running. Clean the surface of the system. See the Operation Manual for details.

5.1.2 Half-yearly Maintenance Clean the guide bar of the microplate holder module and the filter wheel shaft and lubricate them with grease lubricant.

5.2 Service If you want to open the enclosure, power off the system first and release the screws shown in the figure below.

Screws


5-3

5.2.1 Replacing Lamp Replace the lamp with a new one when the system instructs to do or the service time of the lamp has added up to 2,000 hours. 1

Power off the system. Wait at least 30 minutes for the lamp and its housing to cool down.

CAUTION: The hot lamp and its housing may burn you. Be sure not to go to the next step until they have cooled down. 2

Remove the screws on the front of enclosure and open the enclosure.

3

Pinch the rear of the lamp and gently press it down. Pull the lamp out as you see its opening out of the lamp housing. Be sure to pinch the lamp tightly to avoid the lamp damage caused by spring force.

4

Remove the lamp from the lamp base.

5

Insert a new lamp into the lamp base.

6

Pinch the rear of the lamp. Keep the center of the lamp rear a little lower than the center of the lamp opening and move the lamp gently to press the extension spring in the lamp housing. When the lamp opening reaches the locating hole in the lamp housing, raise the lamp rear gently and the lamp will be located automatically by the spring force. Be sure to pinch the lamp tightly to avoid the lamp damage caused by spring force.

CAUTION: Never touch either the light entrance of the lamp or the convex lens in the lamp housing. In case the entrance is dirty, clean it with ethanol-soaked defatted cotton.

5.2.2 Replacing Filter 1

Power off the system. Wait at least 30 minutes for the filter wheel to cool down.

CAUTION: The hot filter wheel may burn you. Be sure not to go to the next step until it has cooled down. 2


3

Use a hex wrench to release the retaining screw on the filter wheel shaft. Push the shaft into the hole and remove the filer wheel.

4

Use a phillips screwdriver to remove the screws on the press plate of the filter wheel. After removing the press plate and pressure springs, replace the filters with new ones. Then assemble the filter wheel in the reverse sequence.

CAUTION: Never touch optical parts, such as filters and diaphragms. Place each filter into its own hole in the filter wheel.

5-4


5.2.3 Replacing Optical Fiber 1

Power off the system.

2


3

Use a phillips screwdriver to release the five retaining screws on the microplate holder module and remove the module.

4

Disconnect the cable between the optical coupler and the driver board. Use a hex wrench to release retaining screws and disassemble the optical fiber box.

5

Use a phillips screwdriver to release the four retaining screws on the optical fiber box cover and remove the cover.

6

Use a hex wrench to release the retaining screws on all fiber ends. Remove the eight small ends and then the big end to remove the whole fiber.

7

Put the big end of the new fiber into the box and then the eight small ends. Be sure to rotate the big end slightly to make the fiber smooth. Put the ends close to the inside surface of the box and secure them with retaining screws.

8

Complete the assembling in the reverse sequence of steps 3-5.

CAUTION: The curve radius of the fiber must be larger than or equal to 20cm. Otherwise, the fiber may be damaged.

5.3 Adjustment 5.3.1 Adjusting Filter Wheel Motor Assembly Be sure to install the filter wheel assembly before adjusting or installing the filter wheel motor assembly. When disassembling/assembling the filter wheel equipped with the system, you need not adjust the filter wheel motor assembly. It is recommended to check if the filter wheel and the motor gear mesh well after the filter wheel, especially a new one, is installed. Adjust the location of the filter wheel motor assembly as necessary. 1


2


3

Install the filter wheel assembly and then tighten the retaining screw on the shaft. Check if the filter wheel assembly can rotate smoothly.

4

To adjust the location of filter wheel motor assembly: Move the motor assembly close to the filter wheel until there is no back lash between them (you can feel by hand that the filter wheel almost has no circumferential gap). Tighten screws on the bracket to secure the motor assembly.


5-5

5

To check if the filter wheel and the motor gear mesh well: Rotate the gear by hand to make a piece of paper (about 0.04mm thick) move between the gear and the filter wheel. If both of the following are reached, the adjustment is successful. Otherwise, adjust the motor assembly again.

When the paper is between the gear and the filter wheel, feel by hand that the gear and the filter wheel have no circumferential gap between them; When the paper is rotated out, the pressure marks on the paper are of the same size in the gear tooth width direction.

5.3.2 Adjusting Belt Tension of Microplate Holder Module Adjust belt tension after the belt is replaced or loose. 1


2


3

Disconnect the cable connected to the analog board. Use a phillips screwdriver to release screws on the microplate holder module and then remove the module and the cable rack.

4

Release the retaining screw on the tension block. Put the belt tension adjustment fixture against the belt wheel and the roller wheel to make the pressure head on the belt. Rotate the adjustment screw to make the belt tension in the scale range of fixture. Then secure the tension block.

5

Assemble the cable rack and then the microplate holder module. Connect the cable.

5.4 Software Upgrade 5.4.1 Software Upgrade for Driver Board The software of the driver board to be upgraded is listed as below: Software

No.

No.+Version

File/folder included

Software of P89LV51RD2BBC on Driver board of microplate reader

G62526

G62526-XX

meibiao.hex

Main board upgrading

G35269

G35269-XXXXXX

Down300CE.ex e

software(Englihs/CE)

The steps of software upgrade for the driver board are as follows: 1

5-6

Ensure the serial port of PC is connected to the driver board.


2

Double-click the software whose icon is shown as follows to run it.

After the software works, the following dialog box pops up.

3

Set up parameters in the dialog box: Select the model and serial port according to the actual condition; Set Baud Rate to 19200, Check Bit to none, Unit to main control unit, and File to meibiao.hex.

4

Click Start to perform the upgrade.

5

After the upgrade is completed, click Exit.

5.4.2 Software Upgrade for CPU Board You can use a USB flash drive to upgrade software for the CPU board. The software to be upgraded is listed as follows. Software

No.

No.+Version

File/Folder included

Software of CPU board of microplate reader (English)

G62565

G62565-xxxxx

meibiao

G62559-01

G62559-01-xxxxxx

mdres (folder)

Resource microplate English)

package of reader (96A,


5-7

Software

No.

No.+Version

File/Folder included

Print template (English)

G62572-02

G62572-02-xxxxxx

templates (folder)

G62567

G62567-xxxxxx

gs

Resource package of print software (GS) of microplate reader

G62568

G62568-xxxxxx

share (folder)

Printer drive (Hpijs) microplate reader

G62569

G62569-xxxxxx

hpijs

G62570

G62570-xxxxxx

gpio_drv.o

Print software (GS) microplate reader

of

of

Device drive of microplate reader

The steps of upgrade are as follows.

5-8

1

Insert the USB flash drive to the PC. Clear the USB flash drive and ensure it has no virus.

2

Create a directory in the USB flash drive. The directory is \hd\soft\.

3

Copy the files and folders listed in the table above to \hd\soft\.

4

Remove the USB flash disk from PC.

5

Insert the USB flash disk having the copied files and folders to the USB port on the microplate reader.

6

Power on the microplate reader. The initialization takes about 15 seconds and after that the following dialog box pops up.

7

Click Yes and then the following dialog box pops up.


8

The whole upgrade takes about five minutes. As the upgrade is completed, the following dialog box pops up.

Click OK.


5-9

P/N: 0104-20-62564 (1.0)

MR-96A

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