Microbiology Practice Test III

MCQ-Series

Practice Test III

Pre-clinical Sciences Time: 1 hr

Microbiology Email:[email protected] Total Marks: 100 | Pass Mark: 60

MedicalMicrobiology Pleaseuseadarkpencil/pentocompl Pleaseuseadarkpencil/pentocompletethetest.Readtheinstruc etethetest.Readtheinstructionsatthe tionsatthe beginingcarefully.ThisisanSample beginingcarefully.ThisisanSampleTestPaperonMedica TestPaperonMedical/ClinicalMicrobiolo l/ClinicalMicrobiology. gy. PleaseNote:Thereisnonegativemarking.

MultipleChoiceQuestions MultipleChoiceQuestions 1. All of the following organisms organisms cannot be grown grown in (artificial) (artificial) culture culture media media except: A Mycobacterium leprae

C Borrelia burgdorferi

B Treponema pallidum

D Human papillomaviruses

2. Which of the following statements statements about desensitization desensitization is incorrect? A may involve sublingual immunotherapy

C direct the immune response toward humoral immunity

B causes an increase in allergen-specific Ig G

D direct the immune response toward cellular immunity

3. Drug of choice choice for treating treating nongonococcal nongonococcal urethritis urethritis due to Chlamydia Chlamydia trachomatis: trachomatis: A Co-trimoxazole

C Erythromycin

B Azithromycin

D Ofloxacin

4. Spongospo Spongospora ra subter subterranea ranea belongs belongs to to Class: Class: A Myxomycetes

C Plasmodiophoromycetes

B Chytridiomycetes

D Oomycetes

5. The causa causati tive ve agent agent of glan glander ders: s: pseudomallei A Burkholderia pseudomallei

C Burkholderia mallei

B Burkholderia cepacia

D Burkholderia solanacearum

6. What enters enters the human host when an infected Anopheles Anopheles mosquito mosquito bites a person? A Merozoites

C Sporozoites

B Oocysts

D Trophozoites

Pre-clinical Science

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MCQ-Series

Practice Test III

Microbiology

7. Regarding complement complement receptor receptor (CR2), (CR2), spot the correct correct statement statement(s): (s): A acts as a receptor for E-B virus

C helps to clear away immune complexes

binds to com complem plement C3d C3d B binds

binds to to compl complem ement ent C5a C5a D binds

8. One of the following has no relationship relationship with virulence virulence of group group A streptococci: streptococci: A Streptolysin O

C M proteins

B Lipoteichoic acid

D T proteins

9. Transplacental transmission transmission of of infections infections can occur with all of the following except: A Yaws

C Malaria

B Varicella

D Cytomegalovirus

10. Source Source of infectio infection n of Seven-day Seven-day fever: fever: A Swine

C Rat urine

B Dog urine

D Mice

11. Regarding Schistosoma Schistosoma haematobium haematobium,, correct correct statement statement is: A caused by a Nematode

C raw crabs are intermediate host

B treatment of choice is Pyrantel pamoat pamoatee

D eggs hatch in freshwater to produce Miracidia

12. Which of the following following treatment treatment is highly highly effective effective in Schistosomi Schistosomiasis asis due to Schistosoma haematobium? A Pyrantel pamoate

C Ivermectin

B Surgical excision

D Praziquantel

13. Treatmen Treatmentt of choice for for hydatid hydatid cyst due to Echinococc Echinococcosis osis:: A Surgical excision

C Thiabendazole

B Praziquantel

D Bithionol


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MCQ-Series

Practice Test III

Microbiology

14. Killed Killed Trep Trepone onem mes are used used in in A Treponema pallidum haemagglutination haemagglutination (TPHA) (TPHA )

C Treponema pallidum agglutination (TPA)

B Venereal Disease Research Laboratories (VDRL)

D Treponema pallidum immobilization (TPI)

15. The causative causative organi organism sm of Rift Rift Valley Valley fever belong belongss to genus: genus: A Flavivirus

C Phlebovirus

B Orthobunyavirus

D Alphavirus

16. Commercially Commercially available preparation 'Serameba' used in serological serological testing is A Enzyme immunoassay

C Ouchterlony double diffusion

B Counterelectrophoresis

D Latex agglutination technique

17. Which of the following statements statements about Streptolysin-O Streptolysin-O (SLO) is/are is/are incorrect? incorrect? A is a leukocidin

C is oxygen stable

B is a hemolysin

D causes alpha hemolysis

18. The most most widely used used specific specific test for for Treponema Treponema pallidu pallidum: m: A fluorescent treponemal antibody-absorption (FTA-ABS)

C Rapid Plasma Reagin (RPR) D T. pallidum hemagglutination (TPHA)

B Venereal Disease Research Laboratories (VDRL)

19. All of the followin following g are tests for nontre nontreponem ponemal al antigens antigens except: except: A Rapid Plasma Reagin test

C T. pallidum complement fixation

B Wassermann test

D VDRL

20. Which of the following drugs helps to eradicates eradicates dwarf tapeworm tapeworm (Hymenolepis (Hymenolepis nana)? nana)? A Pyrantel pamoate

C Diethylcarbamazine

B Ivermectin

D Praziquantel

21. 21. SV40 V40 is a A avian leukosis virus

C simian cytomegalovirus

B simian polyomavirus

D simian immunodeficiency virus


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MCQ-Series

Practice Test III

Microbiology

22. Regarding Regarding Streptoc Streptococcus occus pyogenes, pyogenes, spot the the correct statem statements: ents: produces es nonant nonantige igeni nicc hemol hemolysi ysin n A produc streptolysin O

C streptolysin S is oxygen instable D serum ASO titer > 180 units indicates infection with S pyogenes

B streptolysin S combines with antistreptolysin O

23. Ig M antibodies antibodies is involved in in which of the the following type type of hypersensitive hypersensitive imm immune une reactions? A Type II hypersensitivity reaction

C Type III hypersensitivity reaction

B Type IV hypersensitivity reaction

D Type I hypersensitivity reaction

24. Treponema pallidum organism is best visible/det visible/detected ected with with A Transmitted light microscopy

microscopy C Phase-contrast microscopy

microscopy B Dark-field microscopy

D Infrared microscopy

25. Not a dim dimorphi orphicc fungu fungus: s: A Coccidioides posadasii

C Histoplasma capsulatum

B Blastomyces dermalitidis

D Cryptococcus gattii

26. What is correct correct about Polio Polio vaccines vaccines?? Note: Note: OPV ? Oral Oral Polio Polio Vaccin Vaccine, e, and eIPV eIPV ? enhanc enhanced ed (inac (inacti tivat vated) ed) poli polio o vaccin vaccine. e. A eIPV has a greater chance of reversion to virulence than OPV

C trivalent OPV has a higher seroconversion rate than monovalent OPV

secretion of IgA is is B OPV-induced secretion less than eIPV-induced secretion of IgA

D monovalent OPV has a higher seroconversion rate than trivalent OPV

27. Which of the following organisms organisms is the causative causative agent of Rat-bite fever? fever? A Spirillum minor

Tropheryma whipplei C Tropheryma

B Bartonella henselae

D Borrelia recurrentis

28. The causative causative agent of Chromoblastomy Chromoblastomycosis cosis (chromomycosi (chromomycosis): s): A Hortaea werneckii

C Piedraia hortai

B Fonsecaea pedrosoi

D Microsporum gypseum


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MCQ-Series

Practice Test III

Microbiology

29. The causative organism of Murray Murray Valley encephalitis belongs to which genus? A Phlebovirus

C Hantavirus

B Alphavirus

D Flavivirus

30. Which of the following Bacteria produce filaments filaments and looks like like Fungi? A Acremonium

C Actinomycetes

B Actinomyces

D Ascomycetes

31. Indicator organism organismss for the presence of pathogenic pathogenic microorganism microorganismss in water includes includes all except: A E. coli

C Streptococcus bovis

B Staphylococcus aureus

D Clostridium perfringenes

32. Madura Madura foot foot is due due to ________ __________ __ infecti infection. on. A Actinomycosis

C Actinomyces

B Actinomycetes

D all of the above

33. Which of the following diseases leaves leaves a sequelae sequelae following following resolution? resolution? Pharyngoconjunctival fever A Pharyngoconjunctival

Norwalk vir viral al gastr gastroen oenter terit itis is C Norwalk

B Epidemic keratoconjunctivitis

D Hantavirus pulmonary syndrome

34. Actinom Actinomycosi ycosiss infecti infection on is is due due to: to: A Actinomycetemcomitans

Actinomyces israelii C Actinomyces

B Actinomadura pelletierii

D Actinomycetes

35. Complement Complement activation activation pathway that plays an important important role role in innate, innate, nonspecific immune defense against invasion by bacteria and fungi: A lectin complement pathway

C classical complement pathway

B alternative complement pathway

both a & b D both

36. Treatmen Treatmentt of choice of Fasciol Fascioliasi iasiss due to Fasciola Fasciola hepatica hepatica is: A Pyrantel pamoate

C Surgical excision

B Diethylcarbamazine

D Bithionol


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MCQ-Series

Practice Test III

Microbiology

37. The causativ causativee organism organism of Lyme Lyme disease: disease: A B. burgdorferi

C B. fragilis

B B. malayi

D B. recurrentis

38. Which of the following following serotypes of C. trachomatis trachomatis is the causative causative agent of Inclusion conjunctivitis of the newborn? A C. trachomatis A

C C. trachomatis D

B C. trachomatis L1

D C. trachomatis B

39. Which Which of the the followin following g is not not an Opsonin Opsonin?? A fibronectin

C complement C3b

B complement C5a

D mannose-binding protein

40. The vector vector of Kyasanu Kyasanurr Forest Forest disease: disease: A Fleas

C Tick

B Mosquito

D Mites

41. A tick-b tick-born ornee viral viral dis diseas ease: e: A Crimean-Congo hemorrhagic fever

C Korean hemorrhagic fever

B Lassa fever

D Hantavirus pulmonary syndrome

42. Monili Monilinia nia fructico fructicola la belon belongs gs to: to: A Basidiomycetes

C Ascomycetes

B Chytridiomycetes

D Zygomycetes

43. Regarding Ebola Ebola viruses, viruses, all of the following statements statements are correct except: except: A negative sense single-stranded RNA virus

C assembly: budding from plasma membrane

belongss to Flavi Flavivir virid idae ae famil family y B belong

D replication: cytoplasm

44. Chines Chinesee live liverr flu fluke ke is Echinostoma ilocanum A Echinostoma

C Clonorchis sinensis

B Hymenolepis diminuta

D Opisthorchis felineus


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MCQ-Series

Practice Test III

Microbiology

45. Francisel Francisella la tulare tularensis nsis is resist resistant ant to: to: A Streptomycin

C Penicillin

B Gentamicin

D Tetracycline

46. Which of the following following of Plasmodium Plasmodium develops and differentiat differentiates es into male male and female female gametocytes? A Trophozoites

C Merozoites

B Sporozoites

D Schizonts

47. The virus virus that that causes causes Banzi belon belongs gs to Genus: A Alphavirus

C Flavivirus

B Hantavirus

D Phlebovirus

48. Regarding Serologic Serologic tests tests for Syphilis, spot the the incorrect incorrect statements statements:: A VDRL remains positive for life

C antigen in FTA-ABS is killed T. palli pallidum dum

B antigen in RPR is beef heart cardiolipin

D FTA-ABS does not decline with treatment

49. According to modified modified Jone's Jone's criteria, which of the following following is not a major manifestation manifestation of Rheumatic fever? A Carditis

C Chorea

B Arthralgia

D Erythema marginatum

50. Oral metro metronidaz nidazole ole is the the treatmen treatmentt of choice choice for A Bacterial Vaginosis

C Ascariasis

B Trichinosis

D Amebic dysentery

51. All of the following following are associat associated ed with Streptococ Streptococcus cus pyogenes pyogenes except: except: A neuraminidase

C lipoteichoic acid

B coagulase

D M protein

52. Basid Basidom omyc ycet etes es:: A Filobasidiella neoformans

C Claviceps purpurea

Neurospora ora crass crassaa B Neurosp

campestris D Agaricus campestris


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18-03-2017

MCQ-Series

Practice Test III

Microbiology

53. Correct about Tetanus and its causative causative organism organism Clostridium Clostridium tetani: A tetanospasmin is a potent exotoxin B C. tetani is a nonmotile pleomorphic organism

C tetanospasmin is heat stable neurotoxin D tetanolysin has a MW of 150000 daltons

54. The enzymes enzymes produced by Clostridium Clostridium perfringens include all except: except: A coagulase

protease se C protea

B lecithinase

D collagenase

55. Which of the following microorganism microorganismss causes indolent indolent cutaneous cutaneous infections? infections? A Mycobacterium kansasii

C Mycobacterium ulcerans

B Mycobacterium scrofulaceum

D Mycobacterium abscessus

56. Croup Croup is is assoc associat iated ed with with:: A Rhinovirus

C Parainfluenza virus

B Coxsackievirus

D Adenovirus

57. A rodentrodent-bor borne ne viral viral dise disease ase:: A West Nile fever

C Lassa fever

B Crimean-Congo hemorrhagic fever

D Rift Valley fever

58. True about Atypical Atypical Mycobact Mycobacteria: eria: Mycobacterium A Group IV includes Mycobacterium abscessus

C Group II includes Mycobacterium ulcerans

pathogeni enicc only only in anima animals ls B pathog

D classified according to Lancefield groups

59. Which Which of the follo following wing fungi fungi are Dermatop Dermatophyte hytes? s? A Trichosporon beigelii

C Blastomyces dermatitidis

B Microsporum gypseum

D Geotrichum candidum

60. Penicill Penicillin in G is is not effectiv effectivee against: against: A S. bovis

C S. pneumoniae

B E. faecalis

D C. perfringens


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MCQ-Series

Practice Test III

Microbiology

61. Noca Nocard rdia iaee are: are: mycobacteria A Atypical mycobacteria

C Spirochaete

B Fungi

D Actinomycetes

62. All of the following following antibiotics antibiotics are are derived from the Streptomyces Streptomyces spp. except: A clavulanic acid

C tetracyclines

B vancomycin

D erythromycin

63. Which Which among among the the given given following following is is a 'threadworm 'threadworm'? '? medinensis A Dracunculus medinensis

Necatorr ameri american canus us C Necato

Strongyloides stercoralis B Strongyloides

D Enterobius vermicularis

64. Green sulfur sulfur bacter bacteria ia belongs belongs to: A Eubacteria

C Archaeabacteria

B Halobacterium

D Algae

65. The most most common common causes of actinomycetoma actinomycetoma (mycetoma): (mycetoma): A Actinomyces israelii

C Actinomycetem comitans

B Actinomyces naeslundii

D Actinomadura madurae

66. Leptospira icterohaemorrhagiae icterohaemorrhagiae is the the cause of of which disease in in humans? humans? A Marsh fever

C Weil's disease

B Ft. Bragg fever

D Swineherd’s disease

67. Drug of first first choice for the treatment treatment of hookworm infestation infestation due to Ancylostoma Ancylostoma duodenale: A Ivermectin

C Thiabendazole

B Mebendazole

D Diethylcarbamazine

68. All of the the followin following g are arbovir arboviral al diseases diseases except except:: Nipah viral viral enceph encephali aliti tiss A Nipah

C Dengue

B Japanese B encephalitis

D Yellow fever


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MCQ-Series

Practice Test III

Microbiology

69. Dwarf tapeworm tapeworm that that infests infests small small intest intestine ine is: is: A Trichinella spiralis

C Hymenolepis nana

B Hymenolepis diminuta

D Dipylidium caninum

70. Haemoci Haemocin n is produ produced ced by: by: A H. influenzae

C S. aureus

B E. coli

D P. aeruginosa

71. Match the following following parasites parasites with the the corresponding corresponding mode mode of transmi transmission: ssion: 1.

Clonorchis sinensis

1. Bite of deer flies

2.

Trichinella spiralis

2. Uncooked pork

3.

Paragonimus westermani

3. Raw crabs

4.

Loa loa

4. Undercooked freshwater fish

5.

Onchocerca volvulus

5. Bite of black fly Simulium

72. Which of the following organisms organisms is generally identified identified by coagulase production? A Staphylococcus epidermidis

C Streptococcus viridans

B Streptococcus pyogenes

D Staphylococcus aureus

73. Which Which of the following following is a nonentero nonenterococcal coccal Group Group D Streptococci Streptococci?? A Streptococcus pyogenes

C Streptococcus bovis

B Streptococcus agalactiae

D Streptococcus viridans

74. Example Example of Type Type III hypersen hypersensit sitivit ivity y reaction: reaction: A Erythroblastosis fetalis

C Serum sickness

B Allergic contact dermatitis

D Tuberculin test

75. Which Which of the follo following wing typical typically ly infects infects cattle? cattle? A Brucella canis

C Brucella suis

B Brucella melitensis

D Brucella abortus

76. All of the following following are examples examples of organisms organisms that causes Zoonoses except: except: A Streptobacillus moniliformis

C Brucella melitensis

B Trypanosoma cruzi

D Streptomyces coelicolor


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MCQ-Series

Practice Test III

Microbiology

77. Histolysai Histolysain n which which is is a cyste cysteine ine protease, protease, is is secrete secreted d by: Histoplasma capsulatum A Histoplasma

C Entamoeba histolytica

Ancylostoma duodenale B Ancylostoma

D Schistosoma haematobium

78. Which of the following bears cytotoxic cytotoxic character of hypersensitivity hypersensitivity reactions? A Type II hypersensitivity

C Type IV hypersensitivity

B Type I hypersensitivity

D Type III hypersensitivity

79. The sour source ce of Vancom Vancomyci ycin n is: is: Streptomyces peucetius A Streptomyces

C Ammi majus

B Anamirta cocculus

D Amycolatopsis orientalis

80. All of of the the followin following g are DNA viruses viruses except: except: A Coxsackievirus

C Epstein-Barr virus

B Herpes simplex virus type 1

D Adenovirus

81. Regarding DNA-dependent DNA polymerase, polymerase, which of the the following following statements statements is/are incorrect? A it uses DNA template for catalysis

C catalyse polymerisation only in 3' ? 5' dire direct ctio ion n

B catalyse polymerisation only in 5'? 5'? 3' di direct rectio ion n

D replication is continuous on both strands

82. The Human Influenza Influenza virus isolates isolates includes includes all of the following following information information except: except: A strain number

C year of isolation

B host of origin

D geographic origin

83. In complem complement ent fixatio fixation n test: test: A immune complex fixes the complement and sequesters it

C complement-bound immune complex causes hemolysis

B complement fixes the immune complex and sequesters it

anti-erythrocyte antibody plus D anti-erythrocyte immune complex causes hemolysis

84. The causative causative agent agent of undula undulant nt fever, fever, or Malta Malta fever is: is: A B. bronchiseptica

C B. melitensis

B F. tularensis

D B. malayi


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18-03-2017

MCQ-Series

Practice Test III

Microbiology

85. Ascom Ascomye yecet cetes es:: neoformans A Cryptococcus neoformans

C Rhizopus stolonifer

B Claviceps purpurea

Hicidiomyces apophysatus D Hicidiomyces

86. Regarding Regarding serolo serological gical tests tests for Syphil Syphilis: is: A TPI is a test for nontreponemal antigens

C FTA-ABS is a test for treponemal antigens

B TPHA is a test for treponemal antibodies

D VDRL is a test for nontreponemal antibodies

87. The causative causative agent agent of Lymphog Lymphogranul ranulom omaa venereum venereum:: A Chlamydia trachomatis

C Klebsiella granulomatis

B Haemophilus ducreyi

D Sporothrix schenckii

88. Which Which among among the given given followi following ng is a Helmint Helminth? h? A Trypanosoma cruzi

C Entamoeba histolytica

B Schistosoma haematobium

D Giardia lamblia

89. One of the late sequelae sequelae of strept streptococcu ococcuss pyogenes pyogenes infectio infection: n: A acute glomerulonephritis

pyoderm ma C pyoder

B sore throat

D erysipelas

90. All of the following following microorganis microorganisms ms secrete neurotoxins neurotoxins except: A Corynebacterium diphtheriae

C Clostridium tetani

B Clostridium botulinum

D Clostridium difficile

91. Yellow Yellow fever virus virus is a memb member er of the genus genus A Orthobunyavirus

C Alphavirus

B Phlebovirus

D Flavivirus

92. Regarding Regarding phagocyt phagocytosis osis spot the the incorrect incorrect stateme statements: nts: phagocyto ytosis sis can can occur occur in the the A phagoc absence of serum antibodies

phagocyt ytosi osiss is greatl greatly y enhance enhanced d by C phagoc opsonins

B granulocytic phagocytes live longer than macrophages

phagocyt ytosi osiss causes causes increa increased sed D phagoc glycolysis


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18-03-2017

MCQ-Series

Practice Test III

Microbiology

93. Which of the following statements statements about nongonococcal urethriti urethritiss is/are incorrect? A causative organism is Chlamydia trachomatis

C 50% of women are asymptomatic D dark inclusion bodies characteristic of Chlamydia trachomatis

B 50% of cases of NGU are due to ureaplasma urealyticum

94. Lymphokines Lymphokines and macrophages macrophages are involved in which type type of hypersensitiv hypersensitivity ity reactions? reactions? A Type I hypersensitivity reaction

C Type IV hypersensitivity reaction

B Type III hypersensitivity reaction

D Type II hypersensitivity reaction

95. All of the following primary primary exposure to infection infection provides provides lifelong lifelong immuni immunity ty to reinfections except in: A Infectious mononucleosis

C Herpangina

B Chicken pox

D Measles

96. Zika Zika virus virus belong belongss to Famil Family: y: A Bunyaviridae

C Reoviridae

B Filoviridae

D Flaviviridae

97. An extracellular protein protein that binds binds to prothrombin prothrombin in host cells to to form staphylothr staphylothrombin ombin Neuramin inida idase se A Neuram

C Coagulase

B Hyaluronidase

D Staphylokinase

98. All of the the following following are are dimorph dimorphic ic fungi fungi except: except: Histoplasma capsulatum A Histoplasma

C Penicillium marneffei

neoformans B Cryptococcus neoformans

D Sporothrix schenckii

99. In Heterophyiasis, Heterophyiasis, the parasite Heterophyes heterophyes heterophyes infects infects which organ systems systems of humans? A Liver

C Lymph nodes

B Small intestine

D Subcutaneous

100. The causative organism of necrotizing necrotizing fasciitis fasciitis due to flesh eating bacteri bacteri is: A Clostridium perfringens

C Streptococcus pyogenes

B Staphylococcus aureus

D Klebsiella oxytoca


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MCQ-Series

Practice Test III

Microbiology

Disclaimer:Thisquestionseriesisamocktestforpractice.Studentscanundertakethe examundertimesettings.Thismocktestisdesignedtorecapcriticalandessential factsrelatedtoPre-clinicalsciencedomains.Questionsarebasedontheoretical understandingofthetopicswhichlinkstobedsideclinicalapproach. Pleasenote:MultipleChoiceQuestionswithinaccuratelanguageorwrongchoices maybetterbeleftunanswered.Thispracticeseriesisavailablefreetodownload,and designedforthebenefitofgraduateandpost-graduatemedicalstudents. Everyattempthasbeenmadetovalidateeachandeveryquestion/answer.All remainingerrorsaredeeplyregretted.Authorwillnotbeheldresponsibleforany errors.Pleaseconsultthestandardtextbooksgiveninthereferencesectionfor anydiscrepancy. ReferenceTextbooks: 1.MedicalMicrobiology:Jawetz,Melnick&Adelberg's,24thEdition,Lange McGraw-Hillpublications 2.Microbiology:PrescottM.Lansing(Ed):Prescott-Harley-Klein,5thEdition McGraw-Hillpublications Author AuthorEm Email: ail:sidha sidhart rta12 a123@ 3@yah yahoo. oo.com com


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Microbiology Practice Test III

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