In humans, what organ is considered Thymus responsible for producing T lymphocytes? Cells that syntesize antibody are?
Mature B lymphocytes
Rejection of a transplant is characteristic of Cellular immune which of the immune response systems? system The secondary or anamnestic response causes proliferation of what antibodies?
IgG
The primary response causes proliferation IgM of what antibodies? Immunoglobulins are part of what type of immunity?
Humoral
Which lymphocytes are responsible for cellular immunity, tissue graft rejection, delayed hypersensitivity reactions and immunologic surveillance?
T lymphocytes
A low molecular-weight substance that rarely stimulates the production or Hapten antibodies, but can react with an antibody if present. When can hapten ilicit an immune response?
When attached to a carrier protein
An antigen that reacts with antibodies from Alloantigen within the same species. An antibody produced in response to an Autoantibody antigen possessed by the same individual. An antibody produced in one species that reacts with an antigen from another species.
Heterophile antibody
What is another name for a Heterophile antibody?
xenoantibody
What immune antibody reacts best at 37C, IgG resistant to treatment with sulfhydryl compounds, and often requires the addition of antihuman globulin to produce 1
agglutination? Which of the immune antibodies is the largest, arranged in a pentamer, and cannot cross the placental barrier?
IgM
Which immune antibody activates the complement cascade by way of the alternate pathway once aggregated?
IgA
Which immune antibody is a reaginic antibody that binds to mast cells by the Fc IgE portion and is associated with immediate hypersensitivity? By their amino acids in How are the 5 classes of immunoglobulins the constant region of distinguished? their heavy classes. Which phenomenon is due to excess of antibody in relation to antigen, preventing the formation of a lattice?
prozone due to antibody excess.
Which test for syphilis is primarily used for screening for the treponemal antibody; is RPR sensitive but lacks specificity? Which laboratory test is specific and is used for a comfirmatory test when testing for the treponemal antigen?
FTA-ABS
What substance is produced by the liver in inflammation, necrotic, and infectious CRP diseases? What type of test is the ASO test?
neutralization test
The antistreptolysin O present in a person with group A streptococcal infection, No lysis of the red neutralizes the reagent streptolysin. What blood cells. is the postive result going to show? Which blood group antibody is mainly IgM, reacts best at 4C, associated with atypical Anti-I pneumonia, and cold autoimmune hemolytic anemia? Which antigens should be tested for when HLA antigens assessing histocompatibility for organ transplantation, paternity testion, or for the
2
selection of platelet and granulocyte donors? What is the minimum time interval for blood 8 weeks donation? The blood group that reacts LEAST strongly with anti-H lectin is?
A1B
The blood group that reacts the strongest with anti-H lectin is?
O
Which 2 antibodies are most often naturally occurring, react best at room temp., and anti-M and anti-N can agglutinate cells in saline medium? Which blood group system antigens are primarily in the plasma and adsorbed onto Lewis red cells. Which type of blood group cells are used for antibody screening tests?
Group O, Rh-pos
Cell bound IgG may Why is it important that antiglobulin serum detach from the red be added immediately after washing the cells if delayed cells? addition. A patient who has repeated severe nonhemolytic febrile transfusion reactions and Leukocyte-Poor Red requires transfusion of blood for oxygenBlood Cells carryig capacity should be transfused with what type of blood product? What test is the best and quickest way to Direct antiglobulin test determine acute hemolysis in a transfusion on the posttransfusion reaction? specimen Which antibody is most often associated with delayed hemolytic transfusion reactions?
Jka
An acute hemolytic transfusion reaction is most commonly due to?
An ABO mismatch
Be processed into What should be done with a donor unit that components that contains 37 degree C reacting antibodies? contain minimal amounts of plasma. Whole blood collected in CPDA-1 may be
3
35 days
stored for how many days? What is the only solution that can be added to blood or components before or during a Normal Saline. transfusion? The temperature of a refrigerator that contains stored blood should not exceed what temperature?
6 degrees C
What is the term for average strength of Avidity binding between antigens and antibodies? What is the term for nonspecific attachment of substances to the surfaces of insoluble particles?
Adsorption
What is the term for the use of reagents to remove certain antigens from a mixture by Absorption serologic reaction? Allergic reaction to grass pollen is an example of which type of hypersensitivity reaction?
type I hypersensitivity reaction
Anaphylactic reactions that occur with in minutes and are mediated by IgE antibodies are considered which type of hypersensitivity reaction?
Type I hypersensitivity reaction
Autoimmune hemolytic anemias and thrombocytopenic purpura are caused by antibodies directed against an individual's own red cells. Which type of hypersensitivity reaction is this?
Type II hypersensitivity reaction
Immune complexes are deposited in an individuals tissues in the diseases of Systemic lupus erythematosus and poststreptococcal glomerulonephritis. Which type of hypersensitivity reaction is this?
Type III hypersensitivity reaction.
During TB skin reaction and contact dermatitis, sensitized T cells release lymphkines following a secondary exposure to antigen. Which type of hypersensitivity reaction is this?
