HAAD Examination - Sample Questions by Pinoy Med Tech International on Sunday, November 20, 2011 at 6:18am HAAD EXAM Notes 0ctober 7, 2011 1.
Me ng Computation for the Coefficient of Variation, given na anf SD nya, kukuhanin mo na lang ang Mean ; eto po ang formula
Mean= kunin nyo lang average ng given vaules CV = 1.
(SD x100) /mean The analyte that is increased in Myocardial Infarction Aspartate and Creatine Kinase
1.
There’s a question about CBC with a normal Hct and RBC Ct. but mapapasin nyo na yung MCHC nya eh umabot ng 3-folds sa normal plus o ang iba pang RBC indces nya, -indicative of Codl agglutinin Disease.
What would you do Ans; Warm the sample @ 37 degree celscius 4. In chronic active hepatitis, high titers of which of the following antibodies are seen? a. antimitochondrial b. anti-smooth muscle - answer c. anti-DNA d. anti-parietal cell
1.
In the indirect fluorescent antinuclear antibody test, a speckled pattern may indicate the
presence of antibody to: a. histone b. Sm c. RNA d. DNA - answer
6. Which of the following is associated with Glanzmann's thrombasthenia?
a. normal bleeding time b. normalADP aggregation c. abnormal initial wave ristocetin aggregation d. absence of clot retraction-answer 7. A patient has had massive trauma involving replacement of one blood volume with Red Blood Cells and crystalloid. She is currently experiencing oozing from mucous membranes and surgical incisions. Laboratory values are as follows: PT Normal APTT Normal Breeding time Prolonged Platelet count 20 x 1 03/@ Hemoglobin 1 1.4 g/dL
What is the blood component of choice for this patient?
a. Platelets b. Cryoprecipitated AHF c. Fresh Frozen Plasma d. Prothrombin Complex -Pero sa case na to, nireshuffle lang nila yung question, Given ang blood component tapos ang itatanong e kung alin ang mag pprolong na Test Answer; BLEEDING TIME ; Increased
8. A patient had a multiple transfusion of whole blood, suddenly the patient develops bleeding and oozing from mucous membranes, this is indicative of Dilultional thrombocytopenia - answer Dilutional Coag Factor def The following results were obtained on an electronic particle counter:
Patient Normal WBC 5.1x103/p~ 5.0-10.0x103/~ RBC 2.94 x lo6/ .6-6.2 x lo6/&
low
Hgb 13.8 g/dL 4- 1 8 g/dL
low
Hct 35.4% -0%-54% MCV 128 fL 82-90 fL MCH 46.7 pg 27-31 pg
low high high
MCHC 40% 32%-36%
high
What step should be taken before recycling the sample? a. clean the apertures b. warm the specimen -answer c. replace the lysing agent d. dilute the specimen -suspect a cold agglutinin’s are present
9. There is a question abou a sickle cell patient who develops shortness of breath, sharp and -intense pain in the lower back; this is due to
-Splenic sequestration crisis / vaso occlusive crisis
10. In the indirect fluorescent antinuclear antibody test, a speckled pattern may indicate the presence of antibody to: a. histone b. Sm- answer c. RNA d. DNA Anti-smooth muscle antibodies are antibodies (immunoglobulins) formed against smooth muscle. These antibodies are typically associated with autoimmune hepatitis. Anti-DNA – for Systemic lupus Erythematosus (SLE)
11. Gaucher’s Dse - It is a genetic disease in which a fatty substance (lipid) accumulates in cells and certain organs – Tay Sach’s Dse - disease occurs when harmful quantities of gangliosides accumulate in the nerve cells of the brain, eventually leading to the premature death of those cells. Tangier disease (also known as "Familial alpha-lipoprotein deficiency"[1]:535) is a rare inherited disorder characterized by a severe reduction in the amount of high density lipoprotein (HDL), often referred to as "good cholesterol," in the bloodstream. to sa HAAD)
12. Marker for Hepa B Infection;
(Eto naitanong
HbsAg - answer anti HBS HBsAg: Hepatitis B surface antigen is a marker of infectivity. Its presence indicates either acute or chronic HBV infection.
Anti-HBs: Antibody to hepatitis B surface antigen is a marker of immunity. Its presence indicates an immune response to HBV infection, an immune response to vaccination, or the presence of passively acquired antibody. (It is also known as HBsAb, but this abbreviation is best avoided since it is often confused with abbreviations such as HBsAg.)
Anti-HBc (total): Antibody to hepatitis B core antigen is a nonspecific marker of acute, chronic, or resolved HBV infection.
IgM anti-HBc: IgM antibody subclass of anti-HBc. Positivity indicates recent infection with HBV (within the past 6 mos). Its presence indicates acute infection.
HBeAg: Hepatitis B “e” antigen is a marker of a high degree of HBV infectivity, and it correlates with a high level of HBV replication. It is primarily used to help determine the clinical management of patients with chronic HBV infection.
Anti-HBe: Antibody to hepatitis B “e” antigen may be present in an infected or immune person. In persons with chronic HBV infection, its presence suggests a low viral titer and a low degree of infectivity.
13. Marker for Acute Hepa A infection Anti HAV IgM and IgG Total Anti-HAV IgM -answer
14. Certain antibodies produce this kind of substances that induces red cell lysis in vivo; Complement- answer 15. Which one is a sample of an Auto immune disease --- Hashimoto’s thyroditis 16. Rash, urticaria and Hives are examples of; - Allergic reactions 17. General principle for Platelet storage must be ;
Must be gently agitated RT - answer Must be collected within 12 hrs -wrong 18. Which of the following sets of laboratory findings is consistent with hemolytic anemia? a. normal or slightly increased erythrocyte survival; normal osmotic fragility b. decreased erythrocyte survival; increased catabolism of heme - answer c. decreased serum lactate dehydrogenase activity; normal catabolism of heme d. normal concentration of haptoglobin; marked hemoglobinuria
19. Which of the following would be affected by allowing a urine specimen to remain at room temperature for three hours before analysis? a. occult blood b. specific gravity c. pH- answer d. protein *pH will increase = alkaline urine 20. The pH of a urine specimen measures the: a. free sodium ions b. free hydrogen ions -answer c. total acid excretion d. volatile acids 21. The presence of leukocytes in urine is known as: a. chyluria b. hematuria c. leukocytosis d. pyuria-answer 22. An ammonia-like odor is characteristically associated with urine from patients who: a. are diabetic b. have hepatitis c. have an infection with Proteus sp - answer d. have a yeast infection -proteus produces urease which the converts urea in urine into ammonia in the presence of oxygen 23. Which blood component does not require crossmatching? FFP - answer Platelets RBC
24.. Urine that develops a port wine color after standing may contain: a. melanin b. porphyrins-answer c. bilirubin d. urobilinogen 25. Sign of RBC hemolysis ; Dereased RBC Survival rate and Increase Hema catabolism 26. An outbreak of Staphylococcus aureus has occurred in a hospital nursery. In order to establish the epidemiological source of the outbreak, it is helpful to do:
a. plasmid fingerprinting/ pulse/ phage-typing---answer b. serological typing c. coagulase testing d. catalase testing 27. A technologist is reading a Gram stain from a CSF and observes small structures suggestive of gram-negative coccobacilli. Chemistry and hematology CSF results that would indicate bacterial meningitis include:
WBC
Glucose
Protein
increased
increased
increased
b. decreased
decreased
decreased
c . increased
decreased
increased
d. decreased
increased
decreased
a.
-answer
28. The streptococci most likely to have a high MIC (minimum inhibitory concentration) with penicillin are:
a. enterococci-answer b. unable to grow in 6.5% NaCl solution c. typed as Lancefield group A streptococci d. susceptible to bacitracin 29. An unusual number of Mycobacteria gordonae have been isolated. This organism is reported as a "probable contaminant." The MOST likely source is:
a. an outbreak of infections due to Mycobacteria gordonae -answer b. contamination by water organisms
c. contamination of commercial Lowenstein-Jensen tubes d. contamination of the specimen collection containers
Mycobacterium spp commonly isolated as a water contaminant – M. gordonae 30. A CSF exhibits a gram positive cocci in chains, exhibiting a beta hemloysis CAMP Test- answer Camp test positive –beta hemolytic srep B 31. CSF Infection wit a positive Oxidase test Meninggococci – answer When you say meningococci , is is caused by Neisseria meningitidis which is an Oxidase positive org
32. Study the Biochem of the following; E.coli - Indole +, Motile + VP – CitrateA. baumahnii - Catalase positive, Oxidase NEGATIVE, non motile, beta hemolytic P.aerugunosa Oxidase positive, glucose fermetaion, pyocyanin + Klebsiella pneumonia – Indole -, VP +/-, LIA +, Non motile Edwardsiella--- ???? Providencia
-Indole +, H2S-, ODC+
Yersinia enteroclitica ODC, Urea, Indol +ve Proteus – indole +, urease +, swarming 33. In the assay of lactate dehydrogenase, which of the following products is actually measured3 a. NADH -asnwer b.ATP c. lactic acid d. pyruvic acid
LDH-1 (4H) - in the heart and RBCs
LDH-2 (3H1M) - in the reticuloendothelial system
LDH-3 (2H2M) - in the lungs
LDH-4 (1H3M) - in the kidneys, placenta, and pancreas
LDH-5 (4M) - in the liver and striated muscle[1
Usually LDH-2 is the predominant form in the serum. A LDH-1 level higher than the LDH-2 level (a "flipped pattern") suggestsmyocardial infarction (damage to heart tissues releases heart LDH, which is rich in LDH-1, into the bloodstream)
34. The electrophoretic pattern of a plasma sample compared with a serum sample shows a: a. broad prealbumin peak b. sharp fibrinogen peak-answer c. diffuse pattern because of the presence of anticoagulants d. decreased globulin fractio
35. A condition in which erythrocyte protoporphyrin is increase -IDA 36. . Which of the following serum protein fractions is most likely to be elevated in patients with nephrotic syndrome? a. alpha-1 globulin b. alpha-1 globulin and alpha-2 globulin c. alpha-2 globulin and beta globulin--answer d. beta globulin and gamma globulin 37. Acute hepatitis - aminotransferase markedly increase, AST markedly increase ALT slightly increase 38. Analysis of CSF for oligoclonal bands is used to screen for which of the following disease states? a. multiple myeloma b. multiple sclerosis- answer c. myasthenia gravis d. von Willebrand's disease
Multiple Myeloma- Bence Jones Protein Myasthenia Gravis - One test is for antibodies against the acetylcholine receptor
39. A characteristic of the Bence Jones protein that is used to distinguish it from other urinary proteins is its solubility: a. in ammonium sulfate b. in sulfuric acid c. at 40°C-60°C
d. at 100°C-amswer 40. Increased serum albumin concentrations are seen in which of the following conditions? ,' a. nephrotic syndrome b. acute hepatitis c. chronic inflammation d. dehydration-answer 41. A patient's blood was drawn at 8 AM for a serum iron determination. The result was 85 yg/dL. A repeat specimen was drawn at 8 PM; the serum was stored at 4OC and run the next morning. The result was 40yg/dL. These results are most likely due to: a. iron deficiency anemia b. improper storage of the specimen c. possible liver damage d. the time of day the second specimen was drawn-answer
