Drug of Choice in various diseases

Listed here are the recommended drugs for various medical conditions. * ACUTE ASTHMA ATTACK- Bronchodilator (Terbutaline) * ADDISON’S DISEASE - Corticosteroid (Hydrocortisone) * ADHD- Cylert * AIDS- Zidovudine * ALZHEIMER’S DISEASE - Tacrine Hydrochloride * ANGINA PECTORIS- Nitroglycerin * BENIGN PROSTIC HYPERPLASIA- Fenasteride (Proscar) * CARDIAC ARREST- Epinephrine * CEREBRAL EDEMA- Mannitol, Corticosteriods * CHICKEN POX- Acyclovir  * CHORIOCARCINOMA- Methotrexate * CHRONIC ALCOHOLISM- Disulfiram * CHRONIC ASTHMA- Corticosteriod * CONGESTIVE HEART FAILURE- Digoxin, Furosemide * CUSHING’S DISEASE - Glucocorticoid Synthesis Inhibitor (Mitotane) * DELIRIUM TREMENS- Librium * DYSENTERY- Ciprofloxacin * FEBRILE SEIZURE- Phenobarbital * FILARIASIS- Hetrazan * GOUTY ARTHRITIS- Colchicine, Allopurinol * GRAVE’S DISEASE - Propylthiouracil * HEPATIC ENCEPHALOPATHY- Neomycin, Lactulose * HISTOPLASMOSIS- Amphoterecin * HYPERKALEMIA- Kayexalate * HYPERTENSIVE CRISIS- Sodium Nitropusside * HYPOVOLEMIC SHOCK- Dopamine, Dob utamine * INCREASE INTRACRANIAL PRESSURE- Mannitol * LEPROSY- Dapsone * LEPTOSPIROSIS- Tetracycline * MALARIA- Chloroquine * MECONIUM PLUG SYNDROME- Acetylcysteine * MULTIPLE SCLEROSIS- Baclofen * MYASTHENIA GRAVIS- P yridostigmine (Mestinon) * MYOCARDIAL INFARCTION- Morphine Sulfate * MYOCLONIC SEIZURE- Valproic Acid * MYXEDEMA COMA- Levothyroxine * OBSESSIVE COMPULSIVE PERSONALITY DISORDER- Aprazolam (Xanax) * PANIC ATTACKS- Aprazolam (Xanax) * PARAGONIMIASIS- Praziquantel * PARKINSON’S DISEASE - Levodopa * PARTIAL SEIZURE- Carbamazipine * PATENT DUCTUS ARTERIOSUS- Indo methacin * PRETERM LABOR- Yutopar  * PULMONARY EDEMA- Furosemide * RHEUMATOID ARTHRITIS- Aspirin * SCABIES- Lindane * SCHISTOSOMIASIS- Praziquantel * SINUS BRADYCARDIA- Atropine Sulfate * SINUS TACHYCARDIA- Propanolol, Metoprolol * STATUS ASTHMATICUS- Epinephrine * STATUS EPILEPTICUS- Diazepam * TETANUS SPASM- Diazepam * TOURETTE’S SYNDROME - Haloperidol * TRICHOMONIASIS- Metronidazole * TYPHOID FEVER- Chloramphenicol * VENTRICULAR FIBRILLATION- Lidocaine Hydrochloride

Drug of Choice for Different Diseases For MRSA Infection-Vancomycin For Malaria in Pregnancy-Chloroquine For Whooping Cough or Perteusis- Erythromycin For Kawasaki disease-IV Ig For Warferin Overdose-Vit-K  For Heparin Overdose-Protamine For hairy Cell Leukemia-Cladirabine For Multiple Myeloma- Melphalan For CML-Imatinib For Wegner's granulomatosis-Cyclophosphamide For HOCM- Propranolol For Delirium Tremens-Diazepam For Drug Induced Parkinsonism-Benzhexol For Diacumarol Poisoning-Vit-K  For Type-1 Lepra Reaction-Steroids For Type- 2 Lepra Reaction-Thalidomide For Allergic Contect Dermatitis-Steroids For PSVT- 1st-Adenosine, 2nd-Verapamil, 3rd-Digoxin For Z-E Syndrome- Proton Pump Inhibitor  For Chancroid-Cotrimoxazole For Dermatitis Herpetiformis-Dapsone For Spastic Type of Cerebral Palsy-Diazepam For Herpis Simplex Keratitis-Trifluridine For Herpes Simplex Orolabialis-Pancyclovir  For Neonatal Herpes Simplex-Acyclovir  For Pneumocystis carinii Pneumonia- CotrimoxazoleFor Nodulo Cystic Acne-Retinoic acid For Trigeminal Neuralgia-Carbamezapine For Actinomycosis-Penicillin For Plague- Streptomycin For Opioid Withdrawal- Methadone 2nd-Clonidine For Alcohol Withdrawal- Chlordiazepoxide 2nd-Diazepam For Post Herpetic Neuralgia- Fluphenazine For WEST Syndrome-ACTH For Diabetic Diarrhoea- Clonidine For Lithium Induced Neuropathy-Amiloride

MYCOSES

DRUG OF CHOICE

ALTERNATIVE(S)

Aspergillosis

Voriconazole

Itraconazole a

Blastomycosis

An AMB preparation

Echinocandin

Itraconazole (used in milder forms or after more severe disease is stabilized with an AMB a  preparation)

Posaconazole

a

An AMB preparation

Ketoconazole

Itraconazole capsule (for mild to moderate disease)

Fluconazole PO

Echinocandin

ABLC

Candidiasis Candidemia and invasive candidiasis

a

An AMB preparation

Fluconazole IV or PO

ABCD LAMB

Oropharyngeal candidiasis

Fluconazole PO

Ketoconazole Itraconazole Clotrimazole troche  Nystatin oral suspension AMB oral suspension c

AMB IV Esophageal candidiasis

Fluconazole PO

Ketoconazole Itraconazole c

AMB IV

d

Echinocandin Vulvovaginal candidiasis

Coccidioidomycosis

Fluconazole

,e

PO single dose

Ketoconazole

Topical azole preparations

Itraconazole

 Nystatin vaginal tablet

Boric acid

An AMB

Ketoconazole

a

 preparation (for rapidly  progressive disease)

Itraconazole Voriconazole Posaconazole

Fluconazole PO or IV (for  subacute/chronic disease or  coccidioidal meningitis) a

Cryptococcosis

An AMB preparation +Flucytosine

AMB intrathecal

LAMB Voriconazole Posaconazole

Chronic suppressive therapy with fluconazole PO in AIDS patients (lifelong)

g

Itraconazole capsule Chronic suppressive therapy with itraconazole capsule or AMB (weekly) in AIDS  patients (lifelong)

Dermatophytosis (other  than dermatophytic onychomycosis)

Terbinafine

Griseofulvin

Itraconazole capsule

Fluconazole Topical therapy

Histoplasmosis

AMB (for severe disease)

ABLC

Itraconazole (for mild to moderate disease)

ABCD LAMB Ketoconazole Fluconazole

Chronic suppressive therapy with itraconazole capsule in AIDS  patients (lifelong)

Chronic suppression therapy with itraconazole capsule, fluconazole PO or AMB (weekly) in AIDS patients (lifelong)

Onychomycosis Candida

onychomycosis

Dermatophytic onychomycosis

Itraconazole capsule Terbinafine

Griseofulvin

Itraconazole oral capsule

Topical cicloprox

olamine Fluconazole a

Paracoccidioidomycosis

An AMB preparation Itraconazole (for mild to moderate disease)

Pseudallescheriasis

Voriconazole

Ketoconazole

Itraconazole Ketoconazole Posaconazole Sporotrichosis Cutaneous and lymphocutaneous sporotrichosis

Itraconazole

Potassium iodide

Systemic sporotrichosis

An AMB preparation (for severe disease)

Fluconazole PO a

Fluconazole PO

Itraconazole (for mild to moderate disease) Chronic suppressive therapy with itraconazole capsule in AIDS  patients (lifelong) Zygomycosis

a

An AMB preparation

Posaconazole