Patricia Dian A
148114049
Mulia Toyomas
148114062
Aquina Nino
148114055
Alexander ito
14811406!
Dic"y Prasetya
148114052
A#at$a %atna
148114068
De&&y Permatasari
14811405!
'ulius Denis (
1481140!1
Petrus )e&rian
148114058
%a&ulas Tri Nu#ro$o
148114081
(laudia Daranti"a
148114085 148114085
PRASUGREL A. Indikasi Indikasi dan Contoh Contoh Merek Merek Dagan Dagang g
*ntu" +asien den#an masala$ ,antun# yan# serius- seran#am ,antun#- an#io+lasty Mer" Da#an# . /ient Medsca+e- 20163 B. Mekanisme Prasu#rel adala$ se&ua$ +rodru# yan# $arus dimeta&olisme ole$ $ati terle&i$ da$ulu untu" menda+at"an meta&olit a"tinya3 Meta&olit a"tinya a"an menem+el +ada rese+tor +latelet ADP P2'12 yan# a"an mence#a$ a"tiasi dan a#re#asi +latelet3 &at ini meru+a"an anta#onist rese+tor +latelet ADP P2'12
Dru#&an"- 20163 C. Dosis Pertama "ali +em&erian 60 m#3 etela$ itu di&eri"an 10 m# +3o +er$ari- namun ,i"a 77 60 "# ma"a dosis yan# da+at di&eri"an 5 m# +3o +er$ari Medsca+e- 20163 D. Profil Profil Farma Farmakok kokine inetik tik A7%7 7ioaaila&ility . :!8; Pea" +lasma time . <0 min A&sor+tion . :!9; DT%7* Teri"at Teri"at +rotein . meta&olit a"ti- 98; olume olume distri&usi distri &usi . 44=48 > M/TA7>M %a+idly $ydroly?ed in intestine to actie meta&olite ia ('P
MNATN @al=lie . ! $r ran#e- 2=15 $r (learance . 112=166 >$r /xcretion . *rine 68;- eces 2!; Medsca+e- 2016 E. Efek fek Sam Sam ing ing 7leedin#- anemia- sa"it "e+ala- sa"it +un##un#- mual Medsca+e- 20163 F. !ont !ontra rain indi dika kasi si @i+ersensitiitas- actie +at$olo#ic &leedin# misalnya intracranial $emora#i"- stro"e Medsca+e- 20163
G. !e !ele le" "iha ihan
Bele&i$an Prasu#rel mem+unyai ee" yan# le&i$ +oten dan onset ce+at di&andin#"an clo+ido#rel3 Ta&letCise- 20163 #. !ek$rangan Da+at menye&a&"an dan menin#"at"an resi"o ter,adinya +endara$an- tida" da+at di&eri"an "e+ada +asien &erusia diatas !5 ta$un3 Tida" da+at di&eri"an "e+ada +asien yan# a"an men,alani (oronary Artery 7y+ass ratin# (A73 Pem&erian o&at "e+ada +asien Canita $amil +erlu di+ertim&an#"an Medsca+e- 20163
Daftar P$staka
Dru#&an"- 2016- Prasugrel, CCC3dru#&an"3cadru#sD706209- dia"ses tan##al 2! Noem&er 2016Medsca+e- 2016- Prasugrel - CCC3Medsca+e3com+rasu#rel- dia"ses tan##al 2! Noem&er 20163 Ta&letCise- 2016- Prasu#rel @ydroc$loride- CCC3ta&letCise3commedicine= id+rasu#rel= $ydroc$loride- dia"ses tan##al 2! Noem&er 20163
