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SAP HANA Interview questions
ITIL Foundation - 100 Sample Questions
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MCU-FDTMF Medical Foundation College of Medicine Department of Pathology MULTIPLE CHOICE !" The hallmar# of acute inflammation i$ %" Increa$ed &lood flo' (" )u&or* )u&or* calor* calor* dolor increa$ed increa$ed permea&ility permea&ility of microcirculation microcirculation C" Incr Increa$e ea$ed d +a$cu +a$cular lar perm permea& ea&ility ility D" ,a$cula $cularr $ta$i$ $ta$i$ " The mo$t efficient &actericidal compound pre$ent in neutrophil$ i$ the %" %rachidonic %rachidonic acid meta&olite$ meta&olite$ C" Ly$o$omal en.yme$ (" H/-MPO-Halide $y$tem D" Hydrogen pero0ide 1" Leu#otriene$ are deri+ed from arachidonic acid through the help of thi$ en.yme %" Pho$pholipa$e C" Cycloo0ygena$e (" Lipoo0ygena$e D" Lipo0in$ 2" The %" (" C" D"
hallmar# of chronic inflammation i$ Increa$ed permea&ility permea&ility of microcirculation microcirculation Migratio Migration n of macrop macrophag hage$ e$ at $ite $ite of of in3ury in3ury Ti$$u Ti $$ue e de de$tr $truct uctio ion n Mononu Mononuclea clearr cell cell infiltrat infiltration ion
5" % lymph node &iop$y 'a$ diagno$ed a$ tu&erculo$i$" Thi$ type of necro$i$ i$ characteri$tic characteri$tic of %" Coagulati+e C" Ca$eou$ (" Li6uefacti+e D" 7angrenou$ 8" 9hich of the follo'ing $u&$tance$ accumulate$ in athero$clerotic &lood +e$$el$: %" Fatty acid$ acid$ C" Trygliceride$ Trygliceride$ (" Chole$te Chole$terol rol e$ter$ D" Pho$pholipid$ ;" eutrophil$ (" Eo$inophil$ D" Macrophage$ ?" The outcome of throm&o$i$ 'herein the throm&i tend$ to 7)O9 due to depo$ition of additional platelet$* fi&rin and red &lood cell$ %" )e$olution C" Propagation (" Organi.ation D" )ecanali.ation !/" Mo$t common cau$e of death in &urn patient$ 'ho got into $hoc# i$ %" @ep$i$ C" Dehydration (" CHF D" Hemorrhage !!" Thi$ type of hyper$en$iti+ity reaction i$ mediated &y IgE %" Type I C" Type III (" Type II D" Type I, !" One of the three ma3or component$ of acute inflammation include %" %lteration in +a$cular +a$cular cali&er that that lead$ to a decrea$e decrea$e in &lood &lood flo' (" @tructure change change$ $ in the micro+a$cu micro+a$culature lature permitting permitting pla$ma pla$ma protein$ protein$ and and leu#ocyte$ to lea+e the circulation C" Ti$$u Ti$$ue e de$tr de$truct uctio ion n D" Healing Healing &y connect connecti+e i+e ti$$ue ti$$ue
!1" Heat and redne$$ in acute inflammation i$ due to the follo'ing pathogenetic mechani$m %" Increa$ed +a$cular permea&ility C" @ta$i$ (" Increa$ed &lood flo' D" Leu#ocytic margination !2" The uterine endometrial lining thic#en$ during the proliferati+e pha$e of the men$trual cycle" Thi$ i$ due to %" Hypertrophy C" Hyperpla$ia (" Dy$pla$ia D" Metapla$ia !4" 9hich of the follo'ing di$order$ i$ mo$t li#ely to &e a$$ociated 'ith an e0udate$ rather than a tran$udate: %" Conge$ti+e heart failure C" @uppurati+e inflammation (" >ephrotic $yndrome D" Peritoniti$ !5" 9hich of the follo'ing condition$ 'ill >OT cau$e edema: %" @odium retention C" O&$truction of lymph flo' (" Increa$ed hydro$tatic pre$$ure D" Increa$ed oncotic pre$$ure !8" The role of hi$tamine in acute inflammatory re$pon$e include %" Platelet relea$e and aggregation (" Increa$ed +a$cular permea&ility of the +enule$ C" Increa$ed +a$cular permea&ility of the arteriole$ D" Mem&rane ly$i$ !;" The central figure in chronic inflammation i$ the Macrophage &ecau$e of it$ role in %" (rea#do'n of collagen and fi&ronectin (" Production of / and >itric o0ide meta&olite$ C" Emigration from the &lood $tream to $ite of in3ury D" Inhi&ition &y cyto#ine$ and o0idi.ed lipid$ !?" % &iop$y of the $tomach re+eal an area of malignant change characteri.ed &y +ari$i.ed* compactly arranged neopla$tic gland$ lined &y moderately differentiated cell$" 9hich of the follo'ing term$ refer to malignant tumor of glandular epithelium: %" @arcoma C" Teratoma (" Chori$toma D" %denocarcinoma /" 9hich of the follo'ing $tatement$ in >OT true of red infarct$: %" It occur$ in organ$ 'ith dou&le &lood $upply (" Commonly found in the heart and #idney$ C" @een in +enou$ occlu$ion 'ith infarction D" @een in organ$ 'ith 'ell de+eloped ana$tomo$i$ !" 9hich of the follo'ing condition$ i$ a complication of &oth direct in3urie$ to the lung$ and $y$temic di$order$: %" %telecta$i$ C" Diffu$e al+eolar damage (" Pulmonary edema D" Pulmonary conge$tion " 9hich of the follo'ing condition$ of the lung i$ characteri.ed &y a&normal permanent enlargement of the air $pace di$tal to the terminal &ronchiole accompanied &y de$truction of their 'all$ 'ithout o&+iou$ fi&ro$i$: %" Emphy$ema C" Chronic &ronchiti$ (" (ronchial a$thma D" (ronchiecta$i$ 1" % $pectrum of immunologically mediated predominantly inter$titial lung di$order$ cau$ed &y inten$e often prolonged e0po$ure to inhaled organic du$t$ and occupational antigen$ i$ %" Pulmonary al+eolar proteino$i$ (" (ronchioli$ o&literan$-organi.ing pneumonia C" De$6uamati+e inter$titial pneumoniti$ D" Hyper$en$iti+ity pneumoniti$
2" %n acute fe&rile re$piratory di$ea$e characteri.ed &y patchy inflammatory change$ in the lung$ confined to the al+eolar $epta and pulmonary inter$titium %" Primary atypical pneumonia C" (ronchopneumonia (" Lo&ar pneumonia D" Lo&ular &ronchopneumonia 4" % $y$temic di$ea$e of un#no'n cau$e characteri.ed &y non-ca$eating granuloma in many ti$$ue$ and organ$ particularly in the hilar lymph node$* lung$* eye* and $#in i$ %" @ilico$i$ C" Idiopathic pulmonary fi&ro$i$ (" @arcoido$i$ D" %$&e$to$i$ 5" Mo$t common &enign tumor of the lung di$co+ered incidentally a$ a coin le$ion on routine A-)ay e0amination i$ %" (ronchial carcinoid$ C" Hamartoma (" Thymoma D" (ronchogenic cy$t 8" Mo$t common cau$e of a$piration pneumonia i$ ho$pitali.ed patient$ %" @treptococcu$ pneumonia C" Haemophilu$ influen.ae (" @taphylococcu$ aureu$ D" P$eudomona$ aerogino$a ;" Mo$t common type of a$thma that &egin$ in childhood and triggered &y en+ironmental antigen$ $uch a$ du$t* pollen$ and food i$ %" >on-atopic a$thma C" %topic a$thma (" Drug induced a$thma d" Occupational %$thma
?" Mo$t common manife$tation of a$&e$to$ e0po$ure often containing calcium $een on the anterior and po$terior a$pect of the parietal pleura %" %$&e$to$ &ody C" Ferruginou$ &odie$ (" Pla6ue$ D" %mphi&ole 1/" 9hich of the follo'ing $yndrome i$ characteri.ed &y the appearance of proliferati+e glomerulonephriti$ and necroti.ing hemorrhagic inter$titial pneumoniti$: %" 7oodpa$ture $yndrome C" Barteagner $yndrome (" Paraneopla$tic $yndrome D" Lam&ert-Eaton mya$thenic $yndrome 1!" Mo$t common location of $econdary tu&erculo$i$ in the lung %" Hilar area C" Peripheral (" (a$e D" %pe0 1" % fatal complication of ruptured aortic aneury$m and +a$cular trauma %" Chylothora0 C" Hydrothora0 (" Hemothora0 D" Empyema 11" Mang uanito* 5/-year-old man* ha$ &een $mo#ing for many year$* he e0perienced chronic cough and 'eight lo$$ for the pa$t 5 month$* no fe+er no nau$ea and +omiting" He had one &out of hemopty$i$ and 'ent to the E) for con$ultation" A-ray $ho'$ a 5 cm ma$$ on the medial upper lo&e" (roncho$copy $ho'$ a ma$$ on the $egmental &ronchu$" 9hich of the follo'ing cytologic finding$ i$ li#ely to &e found in thi$ patient: %" Pre$ence of acid fa$t organi$m on $putum e0am (" Pre$ence of malignant $6uamou$ cell$ in $putum C" Pre$ence of numerou$ necrotic de&ri$ and inflammatory cell$ in $putum D" Pre$ence of reacti+e me$othelial cell$ in pleural fluid e0am
12" Mang uan* 54-year-old male 'ith a hi$tory of $mo#ing 'ith producti+e cough for many year$ came in at the emergency room 'ith difficulty of &reathing" Che$t A-ray $ho'$ prominent &lood +e$$el$ and large heart" Patient 'ent into cardiore$piratory arre$t" )e$u$citation done &ut to no a+ail" Hi$tologic $ection ta#en from the lung at autop$y $ho'$ enlargement of the mucu$ $ecreting gland$ of the trachea and &ronchi" 9hat i$ the mo$t li#ely diagno$i$: %" Emphy$ema C" Chronic &ronchiti$ (" (ronchial a$thma D" (ronchiecta$i$ 14" Mang Tony* 44-year-old man ha$ no ma3or medical pro&lem$ in the pa$t year* 2 month$ prior to con$ultation the patient e0perience malai$e and 'eight lo$$ of !/ #g" The patient i$ a non-$mo#er* no fe+er* no difficulty of &reathing" Che$t A-ray $ho'$ a multiple $olid nodule$ $cattered throughout the lung field$" 9hat i$ the mo$t li#ely diagno$i$: %" (ronchogenic carcinoma C" Malignant me$othelioma (" Meta$tatic carcinoma D" (ronchioal+eolar carcinoma 15" Mang Toma$* 24-year-old man had an epi$ode of myocardial infarction he 'a$ &rought to the emergency room and 'a$ intu&ated" Upon intu&ation he $uffer$ a$piration of ga$tric content$" For the ne0t 4 day$ he de+elop$ non-reproducti+e cough and fe+er" Che$t A-ray $ho'$ a 1 cm ma$$ in the right lung 'ith ele+ated air fluid le+el" 9hat i$ the mo$t li#ely diagno$i$: %" (ronchopulmonary $e6ue$tration C" %telecta$i$ (" (ronchiecta$i$ D" Lung a&$ce$$ 18" Hemodynamic pulmonary edema $een in conge$ti+e heart failure i$ due to %" Increa$ed oncotic pre$$ure C" Increa$ed hydro$tatic pre$$ure (" Decrea$ed inter$titial o$motic pre$$ure D" Increa$ed al&umin 1;" @udden death in patient$ 'ith pulmonary em&oli$m i$ cau$ed &y %" (loc#age of &lood flo' through the lung$ (" %telecta$i$ C" De+elopment of chronic o&$tructi+e pulmonary di$ea$e D" De+elopment of pulmonary hyperten$ion 1?" % lymphohematogenou$ di$$emination of pulmonary tu&erculo$i$ 'ould gi+e ri$e to %" ,acitary fi&roca$eou$ tu&erculo$i$ C" Tu&erculou$ &ronchopneumonia (" Pott$ di$ea$e D" Miliary tu&erculo$i$ 2/" The plau$i&le mechani$m in the de+elopment of emphy$ema i$ %" Increa$e relea$e of ela$ta$e in neutrophil$ and macrophage$ (" Increa$e alpha-! anti-tryp$in en.yme C" Pre$ence of o&$truction of a tumor of foreign &ody 'ith concomitant infection D" Increa$e re$pon$i+ene$$ of the &ronchial tree 2!" The ma3or cau$e of celiac $prue i$ %" (acterial infection (" Deficiency of ,itamin (! C" Hyper$en$iti+ity to gliadin fraction of 'heat gluten D" Lymphatic o&$truction 2" 9hich of the follo'ing $tatement$ i$ >OT a characteri$tic of 9hipple$ Di$ea$e: %" Cau$ed &y a gram-po$iti+e actinomycete (" It i$ a $y$temic condition that may in+ol+e any organ of the &ody C" There i$ an increa$ed incidence of $mall inte$tinal adenocarcinoma D" ,illi e0panded &y the den$e infiltrate of macrophage$ impart$ a $haggy gro$$ appearance to the inte$tinal muco$al $urface 21" The hi$tologic criterion for the diagno$i$ of acute appendiciti$ i$ &a$ed on finding thi$ type of cell infiltrating the mu$culari$ propia %" Hi$tiocyte$ C" Lymphocyte$ (" Monocyte$ D" >eutrophil$
22" 9hich of the follo'ing $tatement$ i$ >OT a characteri$tic of Crohn$ Di$ea$e: %" %$$ociated 'ith e0trainte$tinal manife$tation$ li#e migratory polyarthriti$ and an#ylo$ing $pondyliti$ (" 7ranulomatou$ reaction in all layer$ of in+ol+ed inte$tine C" )e$pon$e to $urgery i$ good D" @#ip area$ are $een &et'een in+ol+ed $egment$ of inte$tine 24" Di$accharida$e deficiency i$ cla$$ified under 'hich of the follo'ing ma3or cau$e$ of mala&$orption $yndrome %" Defecti+e Intraluminal dige$tion (" Lymphatic o&$truction C" Primary muco$al cell a&normalitie$ D" )educed $mall inte$tinal $urface area 25" In ulcerati+e coliti$* inflammation i$ limited to the %" Muco$a C" @ero$a (" @u&muco$a D" Tran$mural layer 28" Large area$ of hemorrhagic green ulceration of the muco$a and green-&lac# necro$i$ through the 'all* e0tending to the $ero$a of the appendi0 i$ mo$t li#ely a$$ociated to 'hich of the follo'ing $tage$ of acute appendiciti$: %" %cute gangrenou$ appendiciti$ C" %cute $uppurati+e appendiciti$ (" Early acute appendiciti$ D" )uptured acute appendiciti$ 2;" Leon* 4-year-old male complained of intermittent diarrhea and lo'er a&dominal pain" %n upper 7-I $erie$ $ho'ed $egmental narro'ing in the ileum" Micro$copic finding$ of the le$ion $ho'ed inflammation from the muco$a to the $ero$a 'ith the pre$ence of non-ca$eating granuloma$" The mo$t li#ely diagno$i$ i$ %" Celiac $prue C" Crohn$ di$ea$e (" Tropical $prue D" 9hipple$ di$ea$e 2?" Henry* 24-year-old* male $uffer$ from epi$odic a&dominal &loating 'ith flatulence and e0plo$i+e diarrhea after attending a 'ee#-long community cele&ration of the dairy indu$try during the re$t of the year* he doe$ not con$ume mil# $ha#e$ or ice cream and i$ not $ymptomatic" 9hich of the follo'ing condition$ &e$t account$ for the$e finding$: %" Celiac $prue C" Di$accharida$e deficiency (" Ulcerati+e coliti$ D" 9hipple$ di$ea$e 4/" o$ie* 2/-year-old female* ha$ a total $erum &iliru&in concentration of ;" ? mgdl and a direct &iliru&in le+el of 5"; mgdl" The $erum %lanine aminotra$fera$e %LTG le+el i$ !4 UL* and the a$partate aminotran$fera$e %@TG le+el i$ !/; UL" % li+er &iop$y $ho'$ hi$tologic finding$ characteri$tic for @clero$ing cholangiti$" 9hich of the follo'ing ga$trointe$tinal tract di$ea$e i$ mo$t li#ely to coe0i$t in thi$ patient: %" Celiac $prue C" Tropical $prue (" Ulcerati+e coliti$ D" 9hipple$ di$ea$e 4!" % middle-aged male complain$ of food $tic#ing $ome'here &et'een mouth and $tomach" Monometry re+eal$ a peri$tal$i$" The mo$t po$$i&le diagno$i$ i$ %" @teno$i$ due to $e+ere ga$troe$ophageal reflu0 (" Parae$ophageal hiatal hernia C" %chala$ia D" en#er$ di+erticulum 4" o$hua* 4-year-old* medical $tudent de+eloped $harp epiga$tric pain relie+ed &y eating" %n upper 7" I" $erie$ demon$trated a ! cm ga$tric ulcer" 9hich of the follo'ing feature$ i$ not compati&le 'ith the clinical finding$: %" The $i.e of the ulcer doe$ not differentiate a &enign from malignant ulcer" (" Heaping-up margin i$ rare in the &enign ulcer &ut characteri$tic of malignant le$ion C" The &a$e of the peptic ulcer i$ $mooth and clean D" Ulcerati+e le$ion in the greater cur+ature i$ more li#ely to &e cla$$ic peptic ulcer
41" oan* 4-year-old* female* de+eloped diarrhea* a&dominal pain* and rectal &leeding" @igmoido$copy $ho'ed numerou$ ulcer$" Idiopathic inflammatory &o'el di$ea$e 'a$ con$idered" 9hich of the follo'ing finding$ i$ more compati&le to Crohn$ Di$ea$e than to ulcerati+e coliti$: %" Crypt a&$ce$$ formation deep in muco$a (" Increa$e incidence of adenocarcinoma of colon C" P$eudopolyp formation &et'een ulcer$ D" Pre$ence of granuloma$ in the colonic 'all 42" Ce$ar* 14-year-old male had a hi$tory of heart &urn* regurgitation of $our &ra$h* dy$pnea* &urning e$ophageal pain and $lo'ly &ut progre$$i+e dy$phagia" He 'a$ admitted to the emergency room &ecau$e of lo&ar pneumonia" The mo$t po$$i&le cau$e of hi$ pneumonia i$ due to a$piration and can &e attri&uted to 'hich of the follo'ing condition$: %" E$ophageal atre$ia C" @liding hiatal hernia (" )eflu0 e$ophagiti$ D" E$ophageal di+erticulum 44" Imelda* 5-year-old* girl* had a &loc#y* reddi$h &ro'n ra$h and 'a$ treated 'ith a$pirin* $he de+eloped fatty change of the li+er" The mo$t li#ely diagno$i$ i$ %" @u´ @clero$ing panencephaliti$ (" ,aricella-o$ter infection C" )eye$ $yndrome D" Poliomyeliti$ 45" )onnie* 24-year-old* alcoholic 'ent on a &inge for 'ee#$" He 'a$ found comato$e and in li+er failure" Hi$ li+er at autop$y $ho'ed $e+eral hepatocyte$ 'ith hyaline Mallory &odie$ in the cytopla$m" Thi$ finding i$ mo$t typical of %" %lcoholic hepatiti$ C" Hepatic $teato$i$ (" %lcoholic cirrho$i$ D" Hepatocellular tumor 48" Fely* !;-year-old* female* pre$ent$ 'ith a&dominal pain locali.ed to the right lo'er 6uadrant* nau$ea and +omiting* mild fe+er* and an ele+ation of the peripheral leu#ocyte count to !80!/ ?L" E0amination of the $urgically re$ected appendi0 i$ mo$t li#ely to re+eal %" %n appendi0 'ith normal appearance (" >eutrophil$ 'ithin the mu$cular 'all C" Lymphoid hyperpla$ia and multinucleated giant cell$ 'ithin the mu$cular 'all D" % dilated lumen filled 'ith mucu$ 4;" >elia* 1;-year-old* female* complain$ of fatigue and pruritu$" @he i$ found to ha+e high $erum al#aline pho$phata$e and $lightly ele+ated $erum &iliru&in le+el$* and $erum antimitochondrial auto&odie$ are pre$ent" % li+er &iop$y re+eal$ a mar#ed Lymphocytic infiltrate in the portal tract$" Occa$ional granuloma$ are al$o $een" The mo$t li#ely diagno$i$ i$ %" Primary @clero$ing cholangiti$ C" ,iral hepatiti$ ( infection (" Primary &iliary cirrho$i$ D" Impacted gall$tone 4?" The finding$ of multiple* pale* yello'* hard round $tone$ 'ithin the gall&ladder i$ >OT a$$ociated 'ith 'hich of the follo'ing: %" Oral contracepti+e C" O&e$ity (" (iliary infection D" Hyperlipidemia $yndrome$ 5/" Dilated $inu$oid$ and irregular cy$tic $pace$ filled 'ith &lood 'ithin the li+er 'hich may rupture leading to ma$$i+e intra-a&dominal hemorrhage* are mo$t commonly a$$ociated 'ith %" @alicylate$ C" E$trogen (" %na&olic $teroid$ D" %cetaminophen 5!" Tran$mural infarct$ commonly in+ol+e the$e three arterial +e$$el$ of the heart" The LE%@T affected one i$ the %" Left anterior de$cending C" )ight coronary (" Left circumfle0 D" )ight circumfle0
5" The heat failure cell$ are &y nature %" %l+eolar lining cell$ (" Macrophage$
C" Polymorphonuclear cell$ D" Eo$inophil$
51" %ngina that i$ un$ta&le i$ clinically de$cri&ed a$ %" Tran$ient C" Precipitated &y phy$ical $tre$$ (" )elie+ed &y re$t D" Progre$$i+e 52" Thi$ organ i$ not prominent affected in right-$ided failure %" Li+er C" Bidney$ (" Lung$ D" (rain 54" % cardiac ma$$ form an infant on micro$copic e0amination re+ealed <$pider cell$<" 9hat type of tumor i$ thi$: %" Leiomyoma C" )ha&domyoma (" My0oma D" Fi&roma 55" Ca$e$ of patent ductu$ arterio$u$ that are not i$olated are commonly a$$ociated 'ith the follo'ing condition$* E0cept %" ,@D C" Coarctation (" %@D D" Pulmonary $teno$i$ 58" Hi$topathology e0amination of the heart of a patient 'ho died of %MI $ho'ed coagulati+e necro$i$* edema* hemorrhage and neutrophilic infiltrate$" Ho' old i$ the infarct: %" 1/ minute$ C" ! day (" ! hour$ D" ! 'ee# 5;" >oli* !4-year-old* $tudent* had $ore throat and a 'ee# later de+eloped $'ollen 3oint$ and a murmur in the aortic +al+e area" 9hat i$ the diagno$i$: %" Infecti+e endocarditi$ C" @LE (" )heumatic heart di$ea$e D" Diphtheria 5?" Daniel* 14-year-old man* 'ho recently had an infarct de+eloped a loud pericardial friction ru&" Thi$ i$ due to %" %nother infarct C" @erou$ pericarditi$ (" Purulent pericarditi$ D" Fi&rinou$ pericarditi$ 8/" 7eorge* 2/-year-old male* died of $ep$i$ 'ith DIC" Upon autop$y* $mall ma$$e$ of fi&rin throm&i 'ere $een in the heart +al+e$" Ho' do you interpret thi$: %" Patient had infecti+e endocarditi$ C" Patient had >(TE (" Patient had rheumatic heart di$ea$e D" It i$ normal finding 8!" The &ile $alt$ aid in the emul$ification of dietary fat$ in the inte$tine$" They are compo$ed of &ile acid$ that ha+e &een con3ugated 'ith %" %l&umin C" 7lucoronic acid (" %mino acid D" 7luco$e 8" The mil#y appearance of $erum after fat inge$tion i$ called po$t prandial lipemia" The lipemic appearance i$ cau$ed &y the pre$ence of %" Chole$terol C" Fatty acid$ (" Chylomicron$ D" Pho$pholipid$ 81" 9hich of the follo'ing apolipoprotein$* 'hen pre$ent in an increa$ed concentration* 'ould &e a$$ociated 'ith a decrea$ed ri$# of coronary artery di$ea$e: %" %po %-I C" %po (-!// (" %po (-2; D" %po C-II 82" 9hich type of inflammation i$ mo$t characteri$tic of acute rheumatic fe+er: %" Myocarditi$ C" Pancarditi$ (" Pericarditi$ D" Endocarditi$
84" Thi$ di$ea$e of the heart pre$ent$ on early cyano$i$ %" %trial $eptal defect C" Patent ductu$ arterio$u$ (" Truncu$ arterio$u$ D" %trio+entricular $eptal defect 85" 9hich of the follo'ing $tatement$ a&out heart failure i$ true: %" )ight $ided failure may re$ult in hepatomegaly (" Cor pulmonale u$ually i$ due to $e+ere pulmonic $teno$i$ C" The clinical manife$tation of heart failure mo$t commonly reflect right-$ided failure D" Dy$pnea i$ a re$ult of &lood $ta$i$ in the e0tremitie$ 88" 9hich of the follo'ing di$ea$e$ re$ult$ from a familial a&$ence of high-den$ity lipoprotein: %" Bra&&e$ C" 7aucher$ (" Tangier D" Tay-@ach$ 8;" The en.yme that e0i$t$ chiefly in $#eletal mu$cle* heart and &rain i$ gro$$ly acti+e mu$cular dy$trophy and ri$e$ early in myocardial infarction i$ %" Lipa$e C" Tran$mina$e (" Lactate dehydrogena$e D" Creatine #ina$e 8?" uanito* 12-year-old 'a$ found to ha+e total chole$terol of 4 mgdl and an HDL chole$terol of ;1 mgdl" (a$ed on the$e re$ult$* thi$ indi+idual %" I$ a &orderline high ri$# of coronary heart di$ea$e (" @hould &e coun$eled to modify hi$ diet to reduce hi$ total chole$terol C" @hould &e con$ulted to $ee hi$ phy$ician immediate to follo'-up te$ting D" I$ pro&a&ly not &orderline high ri$# for coronary heart di$ea$e" ;/" % &lood $pecimen i$ dra'n for lipoprotein phenotyping" The te$t re$ult$ o&tained are !" Triglyceride$ - 14 mgdl >, 2/-!52 mgdlG " Total chole$terol - !?/ mgdl >, le$$ than // mgdlG 1" Pre&eta - lipoprotein fraction increa$ed 2" (eta- lipoprotein fraction normal 4" Chylomicron$ pre$ent 5" @erum appearance mil#y The &e$t e0planation for the$e re$ult$ 'ould &e that the indi+idual e0hi&ited characteri$tic of %" % normal indi+idual C" Type II hyperlipoproteinemia (" % non-fa$ting $erum protein D" Type I, hyperlipoproteinemia ;!" Hemoglo&in (art$ i$ compo$ed of %" Four alpha chain$ (" Four &eta chain$
C" Four gamma chain$ D" T'o alpha* t'o &eta chain$
;" Ho'ell-olly &odie$ are compo$ed of %" D>% (" )>%
C" Iron D" Mitochondria
;1" The mo$t mature cell that can undergo mito$i$ i$ the %" Myelo&la$t C" Metamyelocyte (" Promyelocyte D" Myelocyte ;2" ,a$odilation and &ronchocon$triction 'ould &e a$$ociated 'ith 'hich &lood cell %" Eo$inophilic C" (a$ophil$ (" >eutrophil$ D" Monocyte$ ;4" Lymphocyte$ that produce immunoglo&ulin$ in re$pon$e to antigenic $timulation are de$ignated %" ( Lymphocyte$ C" Pla$ma cell$ (" T lymphocyte$ D" Thymocyte$
;5" To0ic granulation i$ mo$t commonly o&$er+ed a$ a Cytopla$mic inclu$ion of %" Lymphocyte$ C" Monocyte$ (" Eo$inophil$ D" >eutrophil$ ;8" 9hich of the follo'ing organ$ i$ >OT a $ite for hematopoie$i$ in the fetu$: %" Li+er C" @pleen (" (one marro' D" Bidney ;;" In early infancy the mo$t numerou$ cell$ of the &one marro' are %" Erythro&la$t$ C" 7ranulocytic precur$or$ (" Lymphocyte$ D" Hi$tiocyte$-monocyte$ ;?" 9hich cell cla$$ification i$ de$cri&ed &y the follo'ing @econd mo$t numerou$ cell in the &lood u$ually $mall and round inten$ely &lue cytopla$m and nucleu$ 'ith clumped dar# purple chromatin: %" Monocyte C" Lymphocyte (" >ull cell D" Pla$macyte ?/" 9hich of the follo'ing i$ mo$t +aria&le in normal marro': %" Differential count of 4// cell$ C" ME ratio (" Cellularity D" Iron $tage ?!" 9hich of the follo'ing i$ not a crucial area of )(C $ur+i+al and function: %" Integrity of )(C cellular mem&rane C" Cell meta&oli$m (" Intra+a$cular hemoly$i$ D" hemoglo&in $tructure ?" 9hich of the follo'ing group$ of a&normal hemoglo&in$ are una&le to tran$port or deli+er o0ygen: %" Car&o0yhemoglo&in and methemoglo&in (" Methemoglo&in and fetal hemoglo&in C" Car&o0yhemoglo&in* $ulfhemoglo&in* and fetal hemoglo&in D" Car&o0yhemoglo&in* methemoglo&in and $ulfhemoglo&in ?1" Production of primary granule$ cea$e$ and production of $econdary granule$ commence$ 'ith 'hat cell $tage: %" Myelocyte C" Myelo&la$t (" Promyelocyte D" Metamyelocyte ?2" % decrea$ed in 'hich of the follo'ing la&oratory re$ult$ i$ >OT a u$ual diagno$tic criterion for anemia: %" Hemoglo&in C" hematocrit (" Platelet count D" )(C count ?4" 9hat i$ diagno$tic +alue of reticulocyte count in the e+aluation of anemia: %" Determine$ re$pon$e and potential of the &one marro' (" Determine$ compen$ation mechani$m$ for anemia C" Determine$ the corrected )(C count after the calculation D" Determine$ the potential $ampling error for )(C count ?5" % &one marro' ha$ large cell$ that ha+e eccentric py#notic nuclei" The cytopla$m of the$e cell $tain$ +ery pale and ha$ a $triated appearance %" Mega #aryo&la$t$ C" 7aucher$ cell$ (" )eed-@tern&erg cell$ D" Large myelo&la$t$ ?8" 9hich of the follo'ing i$ >OT a factor to &e e+aluated in the interpretation of a &one marro' a$pirate $mear: %" Maturation of red and 'hite &lood cell$ $erie$ (" ME ratio C" Type and amount of hemoglo&in D" E$timate of &one marro' acti+ity
?;" Lito 8-year-old ha$ a total 9(C count of 20!/ ?L" The differential count i$ a$ follo'$ >eutrophil$ - ; >, " 45G Lypmhocyte$ - 54 >, "12G (and - "/ >, "-G Monocyte$ - "4 >, - "2G 9hich of the follo'ing $tatement$ i$ true: %" The percentage of lymphocyte$ i$ normal (" The a&$olute num&er of lymphocyte$ i$ lo' C" There i$ an a&$olute lymphocyto$i$ D" There i$ a relati+e lymphocyto$i$ ??" The follo'ing condition$ fa+or$ diagno$i$ of CML rather than a leu#omoid reaction* EACEPT %" %&$ence of eo$inophil$ and &a$ophil$ in the peripheral &lood (" Lo' L%P $core 'ith myelo&la$t$ through $eg$ in the peripheral &lood C" Ph chromo$ome D" Enlarge $pleen !//" The principal defect in chronic granulomatou$ di$ea$e i$ in %" Chemota0i$ C" Phagocyto$i$ (" Ly$o$omal function D" Production of o0ygen and radical
)eference Pathologic (a$i$ of Di$ea$e 8 th Edition
